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Physical Review Research 2022年第4期4卷 043153-043153页

作者： Yu-Hsueh Chen Ke Hsu Wei-Lin Tu Hyun-Yong Lee Ying-Jer Kao Center for Theoretical Physics and Department of Physics National Taiwan University Taipei 10607 Taiwan Division of Display and Semiconductor Physics Korea University Sejong 30019 Korea Department of Applied Physics Graduate School Korea University Sejong 30019 Korea Interdisciplinary Program in E·ICT-Culture-Sports Convergence Korea University Sejong 30019 Korea Center for Quantum Science and Technology National Taiwan University Taipei 10607 Taiwan National Center for High-Performance Computing Hsinchu City 30076 Taiwan

We propose a simple and generic construction of the variational tensor network operators to study the quantum spin systems by the synergy of ideas from the imaginary-time evolution and the variational optimization of trial wave functions. By applying these operators to simple initial states, accurate variational ground-state wave functions with extremely few parameters can be obtained. Furthermore, the framework can be applied to spontaneously study symmetry-breaking, symmetry-protected topological, and intrinsic topologically ordered phases, and we show that symmetries of the local tensors associated with these phases can emerge directly after the optimization without any gauge fixing. This provides a universal way to identify quantum phase transitions without prior knowledge of the system.

关键词： Magnetism Topological order Quantum many-body systems Tensor network methods

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Power Efficiency Analysis of a Three-phase Inverter for a BLDC Motor Drive with Varying Speeds and Load Torques

Power Efficiency Analysis of a Three-phase Inverter for a BL...

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2019 IEEE PES Asia-Pacific Power and Energy Engineering Conference, APPEEC 2019

作者： Lee, Yong Keun Kim, Jong Kwang Seoul National University of Science and Technology Graduate School of Nano-IT Design Fusion Seoul01811 Korea Republic of

ISBN: (纸本)9781728108131

The power efficiency of a three-phase inverter for a BLDC motor drive is analyzed theoretically and experimentally with varying rotor speeds and load torques to elucidate the effect of the rotor speed and load torque on the power efficiency. Based on the theoretical analysis and the simulation/experimental results, the power efficiency is not affected by the rotor speed but by the load torque. As the load torque increases, the power efficiency is found to decrease. © 2019 IEEE.

关键词： Electric inverters

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Smart bioelectronic materials and systems for regenerative tissue engineering

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Biomaterials 2025年 323卷 123427页

作者： Sang Hoon Hong Jin Huh Ranjit De RoWoon Park Seung Min Yang Hyunsik Choi Ho Sang Jung Sei Kwang Hahn Department of Materials Science and Engineering Pohang University of Science and Technology (POSTECH) 77 Cheongam-ro Nam-gu Pohang Gyeongbuk 790-784 South Korea. Department of Materials Science and Engineering Pohang University of Science and Technology (POSTECH) 77 Cheongam-ro Nam-gu Pohang Gyeongbuk 790-784 South Korea School of Life Science Handong Global University Pohang 37554 South Korea. Nano-Bio Convergence Department Korea Institute of Materials Science (KIMS) Changwon Gyeongnam 51508 South Korea. Nano-Bio Convergence Department Korea Institute of Materials Science (KIMS) Changwon Gyeongnam 51508 South Korea. Electronic address: jhs0626@kims.re.kr. Department of Materials Science and Engineering Pohang University of Science and Technology (POSTECH) 77 Cheongam-ro Nam-gu Pohang Gyeongbuk 790-784 South Korea. Electronic address: skhanb@postech.ac.kr.

Regenerative medicine with stem cells has played a pivotal role in tissue engineering, demonstrating remarkable potential to address degenerative diseases and tissue deficiencies. Despite its great potential, this field faces significant challenges, including the need to control cellular behavior, achieve real-time monitoring, and standardize stimulation protocols. To address these technical hurdles, the integration of stem cells with smart bioelectronic materials and devices has emerged as a groundbreaking paradigm in regenerative medicine, offering huge potential for improved therapeutic outcomes in various tissue engineering applications. In this review, we provide a comprehensive analysis of smart bioelectronic systems in regenerative medicine. It reviews recent advances in bioelectronic materials for cellular interfacing, functional device platforms, and real-time physiological monitoring and biophysical stimulation systems. Furthermore, it highlights how these technologies are applied in vascular, cardiac, neural, and bone tissue engineering to support the regeneration and functional integration. With representative case studies, this review underscores how regenerative bioelectronics enables dynamic, tissue-specific therapies across biomedical fields.

关键词： Bioelectronics Biomaterials Regenerative medicine Smart healthcare Stem cells

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Trends in bimetallic nanomaterials and methods for fourth-generation glucose sensors

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TrAC - Trends in Analytical Chemistry 2023年 162卷

作者： Naikoo, Gowhar A. Arshad, Fareeha Hassan, Israr U. Omar, Fatima Ba Tambuwala, Murtaza M. Mustaqeem, Mujahid Saleh, Tawfik A. Department of Mathematics and Sciences College of Arts and Applied Sciences Dhofar University SalalahPC 211 Oman College of Engineering Dhofar University SalalahPC 211 Oman Lincoln Medical School University of Lincoln Brayford Pool Campus LincolnLN6 7TS United Kingdom Department of Chemistry National Taiwan University No. 1 Section 4 Roosevelt Road Taipei10617 Taiwan Nano-Science and Technology Program Taiwan International Graduate Program Institute of Physic Academia Sinica Taipei106 Taiwan Department of Chemistry King Fahd University of Petroleum & Minerals Dhahran31261 Saudi Arabia

Diabetes mellitus is one of the most rapidly rising chronic diseases around the globe. To combat these rising numbers, active research has been done in recent years to enhance the sensitivity, selectivity, and specificity of glucose biosensors. Despite the easy availability of these enzymatic glucose sensors, these have demonstrated limitations like low stability, short shelf-life, and being easily altered by physical and chemical environmental factors. To overcome these limitations, non-enzymatic sensors, also called fourth-generation glucose sensors, have been developed. These sensors use nanomaterials and do not employ any enzymes therefore exhibit better shelf life, improved sensitivity, and allow for quick detection of glucose without needing additional steps. In recent years, bimetallic nanocomposite-based fourth-generation glucose sensors have gained widespread attention from the scientific community. Owing to the synergistic effect of two distinct metal nanomaterials, these sensors show enhanced reproducibility and excellent stability as compared to monometallic nanomaterials. In this review, we aim to represent a comprehensive overview of the recent developments in the development of bimetallic nanocomposite-based glucose sensors for rapid and accurate glucose detection. After a brief introduction, we discussed the various bimetallic nanomaterials developed in recent years, followed by a discussion on the mechanism of action of such sensors. We then briefly discussed the industrial challenges of developing such sensors and discussed the advantages and disadvantages of bimetallic nanomaterial-based sensors. We finally concluded the review by highlighting the future perspectives of this new and upcoming field. © 2023 Elsevier B.V.

关键词： Glucose sensors

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Author Correction: Ablation of the deubiquitinase USP15 ameliorates nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

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EXPERIMENTAL AND MOLECULAR MEDICINE 2024年第10期56卷 2324-2324页

作者： Baek, Jung-Hwan Kim, Myung Sup Jung, Hye Ryeon Hwang, Min-Seon Lee, Chan-ho Han, Dai Hoon Lee, Yong-ho Yi, Eugene C. Im, Seung-Soon Hwang, Ilseon Kim, Kyungeun Chung, Joon-Yong Chun, Kyung-Hee Department of Biochemistry & Molecular Biology Graduate School of Medical Science Brain Korea 21 Project Yonsei University College of Medicine Seoul South Korea Department of Molecular Medicine and Biopharmaceutical Sciences School of Convergence Science and Technology and College of Medicine or College of Pharmacy Seoul National University Seoul 03080 South Korea Department of Surgery Yonsei University College of Medicine Seoul South Korea Department of Internal Medicine Yonsei University College of Medicine Seodaemun-gu Seoul 03722 South Korea Department of Physiology Keimyung University School of Medicine Daegu 42601 South Korea Department of Pathology Keimyung University School of Medicine Daegu South Korea Department of Pathology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul 03181 South Korea Laboratory of Pathology Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda MD 20892 USA

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Journey across extrinsic tactics for power improvements of triboelectric energy harvesting beyond intrinsic materials and device structures: A concise review

Nano Trends

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nano Trends 2025年 9卷

作者： Tamim, Ahmed Mahfuz Lee, Yebin Park, Jung Hwan Hwang, Geon-Tae Jeong, Chang Kyu Department of Energy Storage/Conversion Engineering of Graduate School & Hydrogen and Fuel Cell Research Center Jeonbuk National University Jeonbuk Jeonju 54896 South Korea Division of Advanced Materials Engineering Jeonbuk National University Jeonbuk Jeonju 54896 South Korea Department of JBNU-KIST Industry-Academia Convergence Research Jeonbuk National University Jeonbuk Jeonju 54896 South Korea Department of Mechanical Engineering (Department of Aeronautics Mechanical and Electronic Convergence Engineering) Kumoh National Institute of Technology Gyeongbuk Gumi 39177 South Korea Department of Materials Science and Engineering Pukyong National University Busan 48513 South Korea

The swift evolution of technologies like the Internet of Things (IoT), artificial intelligence (AI), and big data has created an unparalleled need for self-powered sensors and devices. While traditional power sources such as batteries remain in use, triboelectric nanogenerators (TENGs) have emerged as a promising alternative, capable of converting mechanical energy into electrical energy to power these sensors and devices. However, the practical application of TENGs largely depends on their power output and efficiency. The most promising approaches involve the optimization of material selection, surface modification, and chemical modification techniques to increase the triboelectric effect. Additionally, innovative device designs and charge mechanisms have evolved to improve charge generation and transfer mechanisms, thereby boosting TENG output. This review examines recent progress in methods to improve the power output and power density of TENGs. Rather than concentrating solely on approaches such as material selection, surface modification, or chemical modification, this review explores various strategies for enhancing output power and power density based on solid-solid interactions and alternating current (AC) TENGs. This comprehensive analysis provides valuable insights into current developments in TENG technology, paving the way for future innovations aimed at creating high-performance, self-powered systems for next-generation applications. © 2025 The Author(s)

关键词： Charging mechanism Intermediate layer Power management circuit Power output Switching mechanism

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A sustainable and green approach towards the utilization of biopolymers for effective wound dressing applications: A detailed review

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nano-Structures and nano-Objects 2024年 37卷

作者： Verma, Deepak Okhawilai, Manunya Nangan, Senthilkumar Thakur, Vijay Kumar Gopi, Sreeraj Kuppusamy, Kanagaraj Sharma, Mohit Uyama, Hiroshi International Graduate Program of Nanoscience and Technology Chulalongkorn University Bangkok Thailand Metallurgy and Materials Science Research Institute Chulalongkorn University Bangkok 10330 Thailand Center of Excellence in Polymeric Materials for Medical Practice Devices Department of Chemical Engineering Faculty of Engineering Chulalongkorn University Bangkok 10330 Thailand Biorefining and Advanced Materials Research Centre SRUC Kings Buildings West Mains Road Edinburgh EH9 3JG United Kingdom Centre for Research and Development Chandigarh University Punjab Mohali 140413 India Gdansk University of Technology Faculty of Chemistry Polymer Technology Department Gdansk Poland Molecule Food solutions Pvt Ltd Prestiga Atlanda Karnataka Bengaluru 560034 India Center for Supramolecular Chemistry & Catalysis and Department of Chemistry College of Science Shanghai University 99 Shang-Da Road Shanghai 200444 China Institute of Materials Research and Engineering (IMRE) Agency for Science Technology and Research (A⁎STAR) 2 Fusionopolis Way Innovis #08-03 Singapore 138634 Singapore Department of Applied Chemistry Graduate School of Engineering Osaka University Osaka 565-0871 Japan

Millions of people worldwide are suffering and struggling to obtain the most effective wound care/treatment. In previous years, a steep rise in metabolic disorders such as diabetic wound ulcers has been noticed. The primary function of an effective wound dressing is to protect the wound bed from contamination and provide an accelerated healing environment. Biopolymers, a natural boon, can be used for distinct applications from food packaging, biomedicine, and biomedical applications. Natural and synthetic biopolymers have distinct advantages, such as biocompatibility, biodegradability, and environmental friendliness. Cellulose, chitosan, alginates, hyaluronic acid, collagen, etc., are natural biopolymers primarily used to develop wound dressings. Most common synthetic biopolymers such as PVA, PCL, and PLA are examples of how an individual biopolymer or its blends can be used to develop an effective wound dressing. Biopolymer properties for wound dressing applications can be improved by applying the concepts of nanotechnology, bioengineering, and drug delivery. These improvements may help meet the current and future wound care demands for tissue repair and restoration. The current review focuses on using natural and synthetic functionalized biopolymers for effective wound-dressing applications and exhibiting their antibacterial and antimicrobial properties. © 2024 Elsevier B.V.

关键词： Biopolymer functionalization Drug delivery Natural and synthetic Biopolymers Wound dressings Wounds

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Saca chip enabled circulating tumor cell clusters phenotyping for cancer immunotherapy response monitoring 24

Saca chip enabled circulating tumor cell clusters phenotypin...

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24th International Conference on Miniaturized Systems for Chemistry and Life sciences, MicroTAS 2020

作者： Hsu, Chun-Jieh Kan, Yu-Chia Lee, Chun-Wei Wu, Jen-Kuei Lee, Kang-Yun Feng, Po-Hao Chang, Wei-Chiao Tseng, Fan-Gang Department of Engineering and System Science National Tsing Hua University Taiwan Nano Science and Technology Program International Graduate Program Academia Sinica Taiwan Research Center for Applied Sciences Academia Sinica Taiwan Division of Pulmonary Medicine Department of Internal Medicine Shuang Ho Hospital Taipei Medical University Taiwan Division of Pulmonary Medicine Department of Internal Medicine School of Medicine College of Medicine Taipei Taiwan School of Pharmacy Department of Clinical Pharmacy Taipei Medical University Taiwan

ISBN: (纸本)9781733419017

In the present study, we indicated that the detection of specific subtypes of circulating tumor microemboli (CTM) in post-operative patients could help predict cancer recurrence. By using conventional strategies for detection of non-small-cell lung cancer (NSCLC) circulating tumor cells, is significantly limited due to inherently heterogeneous and dynamic expression of EpCAM, and degradation of cytokeratins during epithelial-tomesenchymal transition. These lead to non-negligible false negative detection of "uncapturable and invisible" single CTCs. To solve the problem, we investigated the clinical significance of CTM subtypes, including single CTCs, multi-CTCs cluster, and WBC-CTCs cluster on SACA chip for studying cancer metastasis and recurrence in patients with lung adenocarcinoma. © 2020 CBMS-0001

关键词： Tumors

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Molecular dynamics insight into drug-loading capacity of dodecylphosphocholine aggregate for doxorubicin

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MCB Molecular and Cellular Biomechanics 2024年 21卷

作者： Shu, Qijiang Lv, Qin Dong, Zhi Wang, Wenping Lin, Zedong Huang, Pengru Institute of Information Yunnan University of Chinese Medicine Kunming650500 China Yunnan Key Laboratory of Southern Medicinal Utilization Yunnan University of Chinese Medicine Kunming650500 China Yunnan Traditional Chinese Medicine Prevention and Treatment Engineering Research Center Yunnan University of Chinese Medicine Kunming650500 China College of Chinese Materia Medica Yunnan University of Chinese Medicine Kunming650500 China Guangdong Provincial Key Lab of Nano-Micro Materials Research School of Advanced Materials Shenzhen Graduate School Peking University Shenzhen518055 China Guangxi Key Laboratory of Information Materials Guangxi Collaborative Innovation Center of Structure and Property for New Energy and Materials School of Material Science & Engineering Guilin University of Electronic Technology Guilin541004 China

The therapeutic effect of doxorubicin (DOX) on various cancers is enticing, but its huge toxic side effects are equally obvious. Loading it into nanocarriers and then delivering the drug is currently the most promising solution. In this work, we investigate the assembly mechanism of dodecylphosphorylcholine (DPC) aggregates for encapsulating DOXs using molecular dynamics simulation with an all-atomic force field. The principal propellants of the drug encapsulation procedure encompass hydrophobic and van der Waals interactions. Additionally, hydrogen bonding and electrostatic interactions wield significant influence in the aggregation dynamics of DPCs. The radial distribution function indicates that when DPC aggregates act as stable carriers exerting strong adhesion to the drugs, intermolecular interactions predominantly manifest within the spatial interval ranging from 0.5 nm to 1.0 nm. All calculated data and visualized images of the system configuration changing with simulation time reveal that after about 30 ns, the changes in DPC aggregation sites tend to ultimately form multiple aggregates and exhibit a good morphology loaded with DOXs. Our study explored the drug-carrying potential of DPC, which provides an important theoretical basis and effective guidance for researchers to design a more suitable DDS for DOX and then break through the bottleneck of the clinical application of DOX. Copyright © 2024 by author(s)

关键词： Molecular dynamics

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Generating function for projected entangled-pair states

arXiv

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arXiv 2023年

作者： Tu, Wei-Lin Vanderstraeten, Laurens Schuch, Norbert Lee, Hyun-Yong Kawashima, Naoki Chen, Ji-Yao Faculty of Science and Technology Keio University 3-14-1 Hiyoshi Kohoku-ku Yokohama223-8522 Japan Center for Nonlinear Phenomena and Complex Systems Université Libre de Bruxelles Belgium University of Vienna Faculty of Physics Boltzmanngasse 5 Wien1090 Austria University of Vienna Faculty of Mathematics Oskar-Morgenstern-Platz 1 Wien1090 Austria Division of Display and Semiconductor Physics Korea University Sejong30019 Korea Republic of Department of Applied Physics Graduate School Korea University Sejong30019 Korea Republic of Interdisciplinary Program in E·ICT-Culture-Sports Convergence Korea University Sejong30019 Korea Republic of Institute for Solid State Physics The University of Tokyo Chiba Kashiwa277-8581 Japan Trans-scale Quantum Science Institute The University of Tokyo Bunkyo Tokyo113-0033 Japan Center for Neutron Science and Technology Guangdong Provincial Key Laboratory of Magnetoelectric Physics and Devices School of Physics Sun Yat-sen University Guangzhou510275 China

Diagrammatic summation is a common bottleneck in modern applications of projected entangled-pair states, especially in computing low-energy excitations of a two-dimensional quantum many-body system. To solve this problem, here we extend the generating function approach for tensor network diagrammatic summation, a scheme previously proposed in the context of matrix product states. Taking the form of a one-particle excitation, we show that the excited state can be computed efficiently in the generating function formalism, which can further be used in evaluating the dynamical structure factor of the system. Our benchmark results for the spin-1/2 transverse-field Ising model and Heisenberg model on the square lattice provide a desirable accuracy, showing good agreement with known results. We then study the spin-1/2 J1-J2 model on the same lattice and investigate the dynamical properties of the putative gapless spin liquid phase. We conclude with a discussion on generalizations to multi-particle excitations. © 2023, CC BY.

关键词： Excited states

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