Carbyne, a one-dimensional (1D) carbon allotrope with alternating triple and single bonds, has the highest known mechanical strength but is unstable to bending, limiting synthesis to short linear chains. Encapsulation...
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DNA tetrahedro n nano structure (DTN) is one of the simplest DNA nano structures and has bee n successfully applied for biose nsin g, imagi ng, and treatment of can cer. To facilitate its biomedical applications and p...
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DNA tetrahedro n nano structure (DTN) is one of the simplest DNA nano structures and has bee n successfully applied for biose nsin g, imagi ng, and treatment of can cer. To facilitate its biomedical applications and pote ntial clinical tran slation, fun dame ntal un derstandi ng of DTN's transportation among major organs in living organisms becomes increasingly important. Here, we describe the efficient renal clearanee of DTN in healthy mice by using positron emission tomography (PET) imaging. The kidney elimination of DTN was later applied for renal function evaluation in murine models of unilateral ureteral obstruction (UUO). We further established a mathematical program of DTN to validate its changes of transportation pattern in healthy and UUO mice. We believe the establishment of pharmacokinetic profiles and mathematical model of DTN may provide in sight for future optimization of DNA nano structures for biomedical applications.
We investigate the thermal-transport properties of the kagome antiferromagnet Cd-kapellasite (Cd-K). We find that a field-suppression effect on the longitudinal thermal conductivity κxx sets in below approximately 25...
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We investigate the thermal-transport properties of the kagome antiferromagnet Cd-kapellasite (Cd-K). We find that a field-suppression effect on the longitudinal thermal conductivity κxx sets in below approximately 25 K. This field-suppression effect at 15 T becomes as large as 80% at low temperatures, suggesting a large spin contribution κxxsp in κxx. We also find clear thermal Hall signals in the spin liquid phase in all Cd-K samples. The magnitude of the thermal Hall conductivity κxy shows a significant dependence on the sample’s scattering time, as seen in the rise of the peak κxy value in almost linear fashion with the magnitude of κxx. On the other hand, the temperature dependence of κxy is similar in all Cd-K samples; κxy shows a peak at almost the same temperature of the peak of the phonon thermal conductivity κxxph which is estimated by κxx at 15 T. These results indicate the presence of a dominant phonon thermal Hall κxyph at 15 T. In addition to κxyph, we find that the field dependence of κxy at low fields turns out to be nonlinear at low temperatures, concomitantly with the appearance of the field suppression of κxx, indicating the presence of a spin thermal Hall κxysp at low fields. Remarkably, by assembling the κxx dependence of κxysp data of other kagome antiferromagnets, we find that, whereas κxysp stays a constant in the low-κxx region, κxysp starts to increase as κxx does in the high-κxx region. This κxx dependence of κxysp indicates the presence of both intrinsic and extrinsic mechanisms in the spin thermal Hall effect in kagome antiferromagnets. Furthermore, both κxyph and κxysp disappear in the antiferromagnetic ordered phase at low fields, showing that phonons alone do not exhibit the thermal Hall effect. A high field above approximately 7 T induces κxyph, concomitantly with a field-induced increase of κxx and the specific heat, suggesting a coupling of the phonons to the field-induced spin excitations as the origin of κxyph.
When a charged particle penetrates through an optical interface, photon emissions emerge—a phenomenon known as transition radiation. Being paramount to fundamental physics, transition radiation has enabled many appli...
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When a charged particle penetrates through an optical interface, photon emissions emerge—a phenomenon known as transition radiation. Being paramount to fundamental physics, transition radiation has enabled many applications from high-energy particle identification to novel light sources. A rule of thumb in transition radiation is that the radiation intensity generally decreases with the decrease of particle velocity v; as a result, low-energy particles are not favored in practice. Here, we find that there exist situations where transition radiation from particles with extremely low velocities (e.g., v/c<10−3) exhibits comparable intensity as that from high-energy particles (e.g., v/c=0.999), where c is the light speed in free space. The comparable radiation intensity implies an extremely high photon extraction efficiency from low-energy particles, up to 8 orders of magnitude larger than that from high-energy particles. This exotic phenomenon of low-velocity-favored transition radiation originates from the interference of the excited Ferrell-Berreman modes in an ultrathin epsilon-near-zero slab. Our findings may provide a promising route toward the design of integrated light sources based on low-energy electrons and specialized detectors for beyond-standard-model particles.
Multivalent interactions between protein‐oligomer‐fused binding pairs allowed highly monodisperse assembly of two protein oligomers, where spacing between oligomers can be widely varied. Two different oligomers or t...
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Multivalent interactions between protein‐oligomer‐fused binding pairs allowed highly monodisperse assembly of two protein oligomers, where spacing between oligomers can be widely varied. Two different oligomers or three oligomers can also be discretely assembled into protein layer structures via this *** approaches to design monodisperse protein assemblies require rigid, tight, and symmetric interactions between oligomeric protein units. Herein, we introduce a new multivalent‐interaction‐driven assembly strategy that allows flexible, spaced, and asymmetric assembly between protein oligomers. We discovered that two polygonal protein oligomers (ranging from triangle to hexagon) dominantly form a discrete and stable two‐layered protein prism nanostructure via multivalent interactions between fused binding pairs. We demonstrated that protein nano‐prisms with long flexible peptide linkers (over 80 amino acids) between protein oligomer layers could be discretely formed. Oligomers with different structures could also be monodispersely assembled into two‐layered but asymmetric protein nano‐prisms. Furthermore, producing higher‐order architectures with multiple oligomer layers, for example, 3‐layered nano‐prisms or nanotubes, was also *** a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re‐organized for online delivery, but are not copy‐edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the *** note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Correlated quantum phenomena in one-dimensional (1D) systems that exhibit competing electronic and magnetic order are of strong interest for studying fundamental interactions and excitations, such as Tomonaga-Luttinge...
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Photonic technologies continue to drive the quest for new optical materials with unprecedented responses. A major frontier in this field is the exploration of nonlocal (spatially dispersive) materials, going beyond th...
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