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检索条件"机构=Program in Neuroscience and Medical Scientist Training Program"
520 条 记 录,以下是171-180 订阅
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Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
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Neuron 2025年
作者: Gao, Yu Dong, Qiping Arachchilage, Kalpana Hanthanan Risgaard, Ryan D. Syed, Moosa Sheng, Jie Schmidt, Danielle K. Jin, Ting Liu, Shuang Sandoval, Soraya O. Knaack, Sara Eckholm, Magnus T. Chen, Rachel J. Guo, Yu Doherty, Dan Glass, Ian Levine, Jon E. Wang, Daifeng Chang, Qiang Zhao, Xinyu Sousa, Andre M.M. Waisman Center University of Wisconsin-Madison Madison 53705 WI United States Department of Pediatrics University of Washington School of Medicine Seattle 98195 WA United States Department of Neuroscience University of Wisconsin-Madison Madison 53705 WI United States Wisconsin National Primate Research Center University of Wisconsin-Madison Madison 53705 WI United States Department of Biostatistics and Medical Informatics University of Wisconsin-Madison Madison 53705 WI United States Department of Computer Sciences University of Wisconsin-Madison Madison 53706 WI United States Department of Medical Genetics University of Wisconsin-Madison Madison 53705 WI United States Department of Neurology University of Wisconsin-Madison Madison 53705 WI United States Neuroscience Training Program University of Wisconsin-Madison Madison 53705 WI United States
The prefrontal cortex (PFC) is critical for myriad high-cognitive functions and is associated with several neuropsychiatric disorders. Here, using Patch-seq and single-nucleus multiomic analyses, we identified genes a... 详细信息
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Prospective evaluation of data-driven models to predict daily risk of Clostridioides difficile infection at 2 large academic health centers (vol 2, pg 1, 2022)
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INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY 2023年 第10期44卷 1705-1705页
作者: Kamineni, Meghana Otles, Erkin Oh, Jeeheh Rao, Krishna Young, Vincent B. Li, Benjamin Y. West, Lauren R. Hooper, David C. Shenoy, Erica S. Guttag, John G. Wiens, Jenna Makar, Maggie Electrical Engineering and Computer Science Department Massachusetts Institute of Technology Cambridge Massachusetts Medical Scientist Training Program University of Michigan Medical School Ann Arbor Michigan Department of Industrial and Operations Engineering University of Michigan College of Engineering Ann Arbor Michigan Division of Computer Science and Engineering University of Michigan College of Engineering Ann Arbor Michigan Department of Internal Medicine Division of Infectious Diseases University of Michigan Medical School Ann Arbor Michigan Infection Control Unit Massachusetts General Hospital Boston Massachusetts Division of Infectious Diseases Massachusetts General Hospital Boston Massachusetts Harvard Medical School Boston Massachusetts
Many data-driven patient risk stratification models have not been evaluated prospectively. We performed and compared the prospective and retrospective evaluations of 2 Clostridioides difficile infection (CDI) risk-pre...
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Cooperative Gsx2-DNA binding requires DNA bending and a novel Gsx2 homeodomain interface (Jun, gkae522, 2024)
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NUCLEIC ACIDS RESEARCH 2024年 第13期52卷 8037-8037页
作者: Webb, Jordan A. Farrow, Edward Cain, Brittany Yuan, Zhenyu Yarawsky, Alexander E. Schoch, Emma Gagliani, Ellen K. Herr, Andrew B. Gebelein, Brian Kovall, Rhett A. Department of Molecular and Cellular Biosciences University of Cincinnati College of Medicine Cincinnati OH 45267 USA. Graduate Program in Molecular and Developmental Biology Cincinnati Children's Hospital Research Foundation Cincinnati OH 45229 USA. Medical-Scientist Training Program University of Cincinnati College of Medicine Cincinnati OH 45229 USA. Division of Developmental Biology Cincinnati Children's Hospital Medical Center 3333 Burnet Avenue MLC 7007 Cincinnati OH 45229 USA. Division of Immunobiology Cincinnati Children's Hospital Medical Center 3333 Burnet Avenue Cincinnati OH 45229 USA. Department of Medical Education University of Cincinnati College of Medicine Cincinnati OH 45229 USA. Department of Chemistry Xavier University Cincinnati OH 45207 USA. Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH 45229 USA.
The conserved Gsx homeodomain (HD) transcription factors specify neural cell fates in animals from flies to mammals. Like many HD proteins, Gsx factors bind A/T-rich DNA sequences prompting the following question: How...
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Long-term olfactory loss post-COVID-19:Pathobiology and potential therapeutic strategies
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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年 第2期10卷 148-155页
作者: Sarah Kim John B.Finlay Tiffany Ko Bradley J.Goldstein Department of Head and Neck Surgery&Communication Sciences Duke UniversityDurhamNorth CarolinaUSA Medical Scientist Training Program Duke UniversityDurhamNorth CarolinaUSA Department of Neurobiology Duke UniversityDurhamNorth CarolinaUSA
An acute loss of smell emerged as a striking symptom present in roughly half of the people infected with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virus in the early phases of the COVID-19 *** mos... 详细信息
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Structural and Biophysical Analysis of the Calcium-Activated Chloride Channel Regulator 1 (CLCA1) VWA Domain Suggests Mode of TMEM16A Engagement
SSRN
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SSRN 2019年
作者: Berry, Kayla N. Brett, Tom J. Immunology Program and Medical Scientist Training Program Department of Internal Medicine Division of Pulmonary and Critical Care Department of Cell Biology and Physiology Department of Biochemistry and Molecular Biophysics Washington University School of Medicine St. LouisMO63110 United States
The secreted protein calcium-activated chloride channel regulator 1 (CLCA1) utilizes a von Willebrand Factor type A domain (VWA) to bind to and potentiate the calcium activated chloride channel TMEM16A. To gain insigh... 详细信息
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Regulation of sister chromatid cohesion by nuclear PD-L1
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细胞研究(英文版) 2020年 第7期30卷 590-601页
作者: Jia Yu Bo Qin Ann M.Moyer Somaira Nowsheen Xinyi Tu Haidong Dong Judy C.Boughey Matthew P.Goetz Richard Weinshilboum Zhenkun Lou Liewei Wang Department of Molecular Pharmacology and Experimental Therapeutics Mayo Clinic Rochester MN 55905 USA Department of Oncology Mayo Clinic Rochester MN 55905USA Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN 55905 USA Mayo Clinic Graduate School of Biomedical Sciences Mayo Clinic School of Medicine and the Mayo Clinic Medical Scientist Training Program Mayo Clinic Rochester MN 55905 USA Departments of Urology and Immunology Mayo Clinic Rochester MN 55905 USA Department of Surgery Mayo Clinic Rochester MN 55905 USA
programmed death ligand-1 (PD-L1 or B7-H1) is well known for its role in immune checkpoint regulation,but its function inside the tumor cells has rarely been *** we report that nuclear PD-L1 is important for cancer ce... 详细信息
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Regulation of stem and progenitor cells in the adrenal cortex
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Current Opinion in Endocrine and Metabolic Research 2019年 8卷 66-71页
作者: Finco, Isabella Mohan, Dipika R. Hammer, Gary D. Lerario, Antonio Marcondes Department of Internal Medicine Division of Metabolism Endocrinology and Diabetes University of Michigan Ann Arbor MI United States Medical Scientist Training Program University of Michigan Ann Arbor MI United States Doctoral Program in Cancer Biology University of Michigan Ann Arbor MI United States Department of Molecular and Integrative Physiology University of Michigan Ann Arbor MI United States Rogel Cancer Center University of Michigan Ann Arbor MI United States Department of Cell & Developmental Biology University of Michigan Ann Arbor MI United States
The adrenal cortex is an endocrine organ comprised of three histological zones, the outermost zona glomerulosa, the intermediate zona fasciculata, and the innermost zona reticularis. High plasticity of the adrenal gla... 详细信息
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New strategies for applying targeted therapies to adrenocortical carcinoma
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Current Opinion in Endocrine and Metabolic Research 2019年 8卷 72-79页
作者: Mohan, Dipika R. Lerario, Antonio Marcondes Finco, Isabella Hammer, Gary D. Medical Scientist Training Program University of Michigan Ann Arbor MI United States Doctoral Program in Cancer Biology University of Michigan Ann Arbor MI United States Department of Internal Medicine Division of Metabolism Endocrinology and Diabetes University of Michigan Ann Arbor MI United States Department of Molecular and Integrative Physiology University of Michigan Ann Arbor MI United States Department of Cell & Developmental Biology University of Michigan Ann Arbor MI United States University of Michigan Rogel Cancer Center University of Michigan Ann Arbor MI United States
Adrenocortical carcinoma (ACC) is a rare, aggressive, and frequently deadly cancer. Up to 75% of all patients will eventually develop metastatic disease, and our current medical therapies for ACC provide limited — if... 详细信息
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Abstract #4370 Immune responses at the maternal-fetal interface following restraint stress in late gestation
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Brain, Behavior, and Immunity 2019年 81卷 45-46页
作者: Antonson, A.M. Rajasekera, T.A. Chen, H.J. Gur, T.L. The Ohio State University Institute for Behavioral Medicine Research 460 Medical Center Drive Rm 113 Columbus OH 43210 United States NIDCR CTOC T32 Training Fellowship United States Medical Scientist Training Program United States Department of Psychiatry and Behavioral Health United States
来源: 评论
Rb analog Whi5 regulates G1 to S transition and cell size but not replicative lifespan in budding yeast
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Translational Medicine of Aging 2019年 3卷 104-108页
作者: Crane, Matthew M. Tsuchiya, Mitsuhiro Blue, Ben W. Almazan, Jared D. Chen, Kenneth L. Duffy, Siobhan R. Golubeva, Alexandra Grimm, Annaiz M. Guard, Alison M. Hill, Shauna A. Huynh, Ellen Kelly, Ryan M. Kiflezghi, Michael Kim, Hyunsung D. Lee, Mitchell Lee, Ting-I. Li, Jiayi Nguyen, Bao M.G. Whalen, Riley M. Yeh, Feng Y. McCormick, Mark Kennedy, Brian K. Delaney, Joe R. Kaeberlein, Matt Department of Pathology University of Washington Seattle WA United States Department of Genome Sciences University of Washington Seattle WA United States Medical Scientist Training Program University of Washington Seattle WA United States Department of Biochemistry and Molecular Biology University of New Mexico Albuquerque NM United States Buck Institute for Research on Aging Novato CA United States Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston SC United States
An increase in cell size with age is a characteristic feature of replicative aging in budding yeast. Deletion of the gene encoding Whi5 results in shortened duration of G1 and reduced cell size, and has been previousl... 详细信息
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