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Mental Health in Allergic Rhinitis: Depression and Suicidal Behavior

Current Treatment Options in Allergy 2017年第1期4卷 71-97页

作者： Amritwar, Ameya U. Lowry, Christopher A. Brenner, Lisa A Hoisington, Andrew J. Stiller, John W. Hamilton, Robert Postolache, Teodor T. Mood and Anxiety Program University of Maryland School of Medicine Baltimore MD United States Saint Elizabeths Hospital-DBH Psychiatry Residency Training Program Washington DC United States Department of Integrative Physiology and Center for Neuroscience University of Colorado Boulder Boulder CO United States Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE) Denver CO United States Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC) Denver CO United States Department of Psychiatry Physical medicine and Rehabilitation and Neurology University of Colorado Anschutz Medical Campus Aurora CO United States Department of Civil and Environmental Engineering US Air Force Academy 2354 Fairchild Dr. Suite 6H-161 Colorado Springs CO United States Division of Allergy and Clinical Immunology Department of Medicine Johns Hopkins Asthma and Allergy Center Baltimore MD United States VISN 5 Capitol Health Care Network Mental Illness Research Education and Clinical Center (MIRECC) Baltimore MD United States

A high proportion of suicides visit their medical provider in the month prior to death, but depression, suicidal thoughts, and substance use are seldom addressed. For the clinicians routinely treating a substantial pa... 详细信息

A high proportion of suicides visit their medical provider in the month prior to death, but depression, suicidal thoughts, and substance use are seldom addressed. For the clinicians routinely treating a substantial patient population with allergic diseases, there are additional concerns, as allergy has been linked with both depression and suicidal behavior. While psychotropic medications may affect diagnosis of allergies, medications used to treat allergies impact mood and behavior. Thus, we present an overview of the overlap of allergic rhinitis with depression and suicidal behavior in adults, based on clinical and epidemiological data, and our research and clinical experience. In summary, we suggest: (1) inquiring among patients with allergies about personal and family history of depression, substance use disorders, suicidal ideation, and attempts;(2) increased mindfulness regarding the potential effects of allergy medications on mood and behavior;and (3) for people identified with certain types of depression or increased suicide risk, a systematic multilevel collaborative approach. While, for practical reasons the majority of patients with depression will continue to be treated by general or family practitioners, the allergy-treating provider should always consider integrated care for bipolar, psychotic, or suicidal depression and incomplete remission, or relapsing and highly recurrent course. While awaiting results of a much needed basic and clinical research to guide the clinical approach to patients with comorbid allergic rhinitis and depression, the simple steps recommended here are expected to lead to improved clinical outcomes in depression, and, perhaps, contributing to lowering the highly resilient suicide *** objectives: a) Present overlaps between allergy, allergen exposure, depression, and suicidal behavior in adults and b) Familiarize allergists with the principles of diagnosis and treatment of depression in adults and importance to mon

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Publisher Correction: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

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Nature communications 2019年第1期10卷 5257页

作者： Katherine A Michaelis Mason A Norgard Xinxia Zhu Peter R Levasseur Shamilene Sivagnanam Shannon M Liudahl Kevin G Burfeind Brennan Olson Katherine R Pelz Diana M Angeles Ramos H Carlo Maurer Kenneth P Olive Lisa M Coussens Terry K Morgan Daniel L Marks Medical Scientist Training Program Oregon Health & Science University Portland OR USA. Brenden-Colson Center for Pancreatic Care Oregon Health & Science University Portland OR USA. Papé Family Pediatric Research Institute Oregon Health & Science University Portland OR USA. Department of Computational Biology Oregon Health & Science University Portland OR USA. Department of Cell Developmental and Cancer Biology Knight Cancer Institute Oregon Health & Science University Portland OR USA. Departments of Medicine and Pathology and Cell Biology Columbia University Medical Center New York NY USA. Department of Pathology Oregon Health & Science University Portland OR USA. Brenden-Colson Center for Pancreatic Care Oregon Health & Science University Portland OR USA. marksd@ohsu.edu. Papé Family Pediatric Research Institute Oregon Health & Science University Portland OR USA. marksd@ohsu.edu.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

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Nature biotechnology 2020年第11期38卷 1356页

作者： Hyun Min Kang Meena Subramaniam Sasha Targ Michelle Nguyen Lenka Maliskova Elizabeth McCarthy Eunice Wan Simon Wong Lauren Byrnes Cristina M Lanata Rachel E Gate Sara Mostafavi Alexander Marson Noah Zaitlen Lindsey A Criswell Chun Jimmie Ye Department of Biostatistics and Center for Statistical Genetics University of Michigan School of Public Health Ann Arbor Michigan USA. hmkang@umich.edu. Biological and Medical Informatics Graduate Program University of California San Francisco San Francisco California USA. Institute for Human Genetics (IHG) University of California San Francisco San Francisco California USA. Institute for Computational Health Sciences University of California San Francisco San Francisco California USA. Department of Epidemiology and Biostatistics University of California San Francisco San Francisco California USA. Department of Bioengineering and Therapeutic Sciences University of California San Francisco San Francisco California USA. Medical Scientist Training Program (MSTP) University of California San Francisco San Francisco California USA. Department of Microbiology and Immunology University of California San Francisco San Francisco California USA. Diabetes Center University of California San Francisco San Francisco California USA. Innovative Genomics Institute University of California Berkeley Berkeley California USA. Department of Neurology University of California San Francisco San Francisco California USA. Developmental and Stem Cell Biology Graduate Program University of California San Francisco San Francisco California USA. Department of Medicine University of California San Francisco San Francisco California USA. Rosalind Russell/Ephraim P Engleman Rheumatology Research Center University of California San Francisco San Francisco California USA. Department of Statistics University of British Columbia Vancouver British Columbia Canada. UCSF Helen Diller Family Comprehensive Cancer Center University of California San Francisco San Francisco California USA. Chan Zuckerberg Biohub San Francisco California USA. Lung Biology Center University of California San Francisco San Francisco California USA. Department of Orofacial Sciences Universi

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Correction to: Dynamic linear models guide design and analysis of microbiota studies within artificial human guts

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Microbiome 2018年第1期6卷 212页

作者： Justin D Silverman Heather K Durand Rachael J Bloom Sayan Mukherjee Lawrence A David Program in Computational Biology and Bioinformatics Duke University CIEMAS Room 2171 101 Science Drive Box 3382 Durham NC 27708 USA. Medical Scientist Training Program Duke University Durham NC 27708 USA. Center for Genomic and Computational Biology Duke University Durham NC 27708 USA. Department of Molecular Genetics and Microbiology Duke University Durham NC 27708 USA. University Program in Genetics and Genomics Duke University Durham NC 27708 USA. Departments of Statistical Science Mathematics Computer Science Biostatistics & Bioinformatics Duke University Durham NC 27708 USA. Program in Computational Biology and Bioinformatics Duke University CIEMAS Room 2171 101 Science Drive Box 3382 Durham NC 27708 USA. lawrence.david@duke.edu. Center for Genomic and Computational Biology Duke University Durham NC 27708 USA. lawrence.david@duke.edu. University Program in Genetics and Genomics Duke University Durham NC 27708 USA. lawrence.david@duke.edu. Department of Molecular Genetics and Microbiology Duke University Durham NC 27708 USA. lawrence.david@duke.edu.

AbstractFollowing publication of the original article [1], the authors noticed an error in the presentation of equations in the PDF version.

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SERUM TRIGLYCERIDES IN ALZHEIMER'S DISEASE: RELATION TO NEUROIMAGING, CSF, AND GENETIC VARIATION

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Alzheimer's & Dementia 2019年第7期15卷 P1320-P1321页

作者： Megan Bernath Sudeepa Bhattacharyya Kwangsik Nho Dinesh Kumar Barupal Oliver Fiehn Rebecca Baillie Shannon L. Risacher Matthias Arnold Tanner Y. Jacobson John Q. Trojanowski Leslie M. Shaw Michael W. Weiner P. Murali Doraiswamy Rima F. Kaddurah-Daouk Andrew J. Saykin Indiana University School of Medicine Indianapolis IN USA Indiana Alzheimer Disease Center Indianapolis IN USA Indiana University Medical Scientist Training Program Indianapolis IN USA Department of Medical and Molecular Genetics Indianapolis IN USA University of Arkansas for Medical Sciences Little Rock AR USA Indiana University School of Informatics and Computing Indianapolis IN USA NIH-West Coast Metabolomics Center Davis CA USA NIH-West Coast Metabolomics Center University of California Davis Davis CA USA Rosa & Co LLC San Carlos CA USA Helmholtz Zentrum Muenchen Oberschleißheim Germany German Center for Diabetes Research (DZD) Neuherberg Germany University of Pennsylvania Philadelphia PA USA Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Center for Neurodegenerative Disease Research University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Perelman School of Medicine University of Pennsylvania Department of Pathology and Laboratory Medicine Philadelphia PA USA Center for Imaging of Neurodegenerative Diseases San Francisco Veterans Affairs Medical Center San Francisco CA USA UCSF Department of Radiology and Biomedical Imaging San Francisco CA USA Duke University Medical Center Durham NC USA Duke Institute of Brain Sciences Duke University Durham NC USA Department of Psychiatry and Behavioral Sciences Duke University Durham NC USA Department of Medicine Duke University Durham NC USA Department of Radiology and Imaging Sciences Indiana University School of Medicine Indianapolis IN USA

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Analytical strategies for studying stem cell metabolism

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Frontiers in Biology 2015年第2期10卷 141-153页

作者： James M. Arnold William T. Choi Arun Sreekumar Mirjana Maletic-Savatic Department of Molecular and Cell Biology Baylor College of Medicine Houston TX 77030 USA Program in Developmental Biology and Medical Scientist Training Program Baylor College of Medicine Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital Houston TX 77030 USA Departments of Pediatrics-Neurology and Neuroscience and Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine Houston TX 77030 USA

Owing to their capacity for self-renewal and pluripotency, stem cells possess untold potential for revolutionizing the field of regenerative medicine through the development of novel therapeutic strategies for treatin... 详细信息

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Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease

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Nature communications 2018年第1期9卷 4333页

作者： Rebecca Aron Pasquale Pellegrini Edward W Green Daniel C Maddison Kwadwo Opoku-Nsiah Jinny S Wong Aaron C Daub Flaviano Giorgini Steven Finkbeiner Center for Systems and Therapeutics & Taube/Koret Center for Neurodegenerative Disease Gladstone Institutes 1650 Owens St. 94158 San Francisco CA USA. Taube-Koret Center for Neurodegenerative Disease 94158 San Francisco CA USA. Yumanity Therapeutics 02139 Cambridge MA USA. Department of Genetics and Genome Biology College of Life Sciences University of Leicester Adrian Building University Road LE1 7RH Leicester UK. DKFZ 69120 Heidelberg Germany. Graduate Program in Chemistry and Chemical Biology Department of Pharmaceutical Chemistry University of California-San Francisco 94158 San Francisco CA USA. Center for Systems and Therapeutics & Taube/Koret Center for Neurodegenerative Disease Gladstone Institutes 1650 Owens St. 94158 San Francisco CA USA. sfinkbeiner@gladstone.ucsf.edu. Taube-Koret Center for Neurodegenerative Disease 94158 San Francisco CA USA. sfinkbeiner@gladstone.ucsf.edu. Graduate Program in Biomedical Sciences University of California-San Francisco 94158 San Francisco CA USA. sfinkbeiner@gladstone.ucsf.edu. Graduate Program in Neuroscience University of California-San Francisco 94158 San Francisco CA USA. sfinkbeiner@gladstone.ucsf.edu. Graduate Program in Medical Scientist Training Program University of California-San Francisco 94158 San Francisco CA USA. sfinkbeiner@gladstone.ucsf.edu. Department of Neurology and Physiology University of California-San Francisco 94158 San Francisco CA USA. sfinkbeiner@gladstone.ucsf.edu.

The original version of this Article incorrectly gave a publication date of 8 October 2018; this should have been 28 September 2018. This has now been corrected in the PDF and HTML versions of the Article.

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Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

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Journal of neuroinflammation 2018年第1期15卷 169页

作者： Megan F Duffy Timothy J Collier Joseph R Patterson Christopher J Kemp Kelvin C Luk Malú G Tansey Katrina L Paumier Nicholas M Kanaan D Luke Fischer Nicole K Polinski Olivia L Barth Jacob W Howe Nishant N Vaikath Nour K Majbour Omar M A El-Agnaf Caryl E Sortwell Department of Translational Science and Molecular Medicine Michigan State University 400 Monroe Avenue NW Grand Rapids MI 49503-2532 USA. Neuroscience Graduate Training Program Michigan State University Grand Rapids MI USA. Mercy Health Hauenstein Neuroscience Medical Center Grand Rapids MI USA. Center for Neurodegenerative Disease Research Department of Pathology and Laboratory Medicine University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Department of Physiology Emory University School of Medicine Atlanta GA USA. MD/PhD Program Michigan State University Grand Rapids MI USA. Neurological Disorders Research Center Qatar Biomedical Research Institute (QBRI) Hamad Bin Khalifa University (HBKU) Education City Qatar. Life Sciences Division College of Science and Engineering Hamad Bin Khalifa University (HBKU) Education City Qatar. Department of Translational Science and Molecular Medicine Michigan State University 400 Monroe Avenue NW Grand Rapids MI 49503-2532 USA. caryl.sortwell@hc.msu.edu. Mercy Health Hauenstein Neuroscience Medical Center Grand Rapids MI USA. caryl.sortwell@hc.msu.edu.

After publication of the original article [1] it was noted that the name of author, D. Luke Fisher, was erroneously typeset in both the PDF and online formats of the manuscript as Luke D. Fisher.

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P1-471: QUANTITATIVE T1 IN ALZHEIMER'S DISEASE

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Alzheimer's & Dementia 2018年第7S_PART_9期14卷

作者： Akshay Kohli Andrew P. Merluzzi Jennifer M. Oh Sanjay Asthana Sterling C. Johnson Andrew L. Alexander Steven Kecskemeti Barbara B. Bendlin Neuroscience Training Program University of Wisconsin School of Medicine and Public Health Madison WI USA Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health Madison WI USA Wisconsin Alzheimer's Disease Research Center Madison WI USA Geriatric Research Education and Clinical Center William S. Middleton Memorial Veterans Hospital Madison WI USA VA Geriatric Research Education and Clinical Center William S. Middleton Memorial Veterans Hospital Madison WI USA Department of Medical Physics University of Wisconsin - Madison Madison WI USA

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QUANTITATIVE T1 IN ALZHEIMER’S DISEASE

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Alzheimer's & Dementia 2018年第7期14卷 P503-P503页

作者： Akshay Kohli Andrew P. Merluzzi Jennifer M. Oh Sanjay Asthana Sterling C. Johnson Andrew L. Alexander Steven Kecskemeti Barbara B. Bendlin Neuroscience Training Program University of Wisconsin School of Medicine and Public Health Madison WI USA Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health Madison WI USA Wisconsin Alzheimer's Disease Research Center Madison WI USA Geriatric Research Education and Clinical Center William S. Middleton Memorial Veterans Hospital Madison WI USA VA Geriatric Research Education and Clinical Center William S. Middleton Memorial Veterans Hospital Madison WI USA Department of Medical Physics University of Wisconsin - Madison Madison WI USA

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