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Immunotherapy Bridge 2016 and Melanoma Bridge 2016: meeting abstracts

Journal of Translational Medicine 2017年第1期15卷 1-14页

作者： Vera Hirsh Sandro Pignata Melissa Bersanelli Donatello Gasparro Francesco Leonardi Sebastiano Buti Letizia Gnetti Cinzia Azzoni Lorena Bottarelli Enrico Maria Silini Erik Wennerberg Sandra Demaria Claire Vanpouille-Box Karsten Pilones Nils Rudqvist Julie Diamond Silvia Formenti Aranzazu Mediero Bruce Cronstein Zachary S. Morris Emily I. Guy David M. Francis Monica M. Gressett Eric A. Armstrong Shyhmin Huang Jacquelyn A. Hank Anna Hoefges Alexander L. Rakhmilevich Paul M. Harari Paul M. Sondel Stephen D. Gilles Alan J. Korman Yared Hailemichael Willem W. Overwijk Per thor Straten Alessandro Lugli Heather Dawson Annika Blank Inti Zlobec Luigi Fattore Susan Costantini Maria Elena Pisanu Paolo Antonio Ascierto Gennaro Ciliberto Debora Malpicci Mario Acunzo Giulia Romano Giovanni Nigita Carlo Maria Croce Alessandro Laganà Ciro Francesco Ruggiero Alessia Noto Claudia De Vitis Rita Mancini Michael Postow Jason Luke David Stroncek Luciano Castiello Wenjing Chen Ping Jin Jiaqiang Ren Marianna Sabatino Soldano Ferrone Connie PM Duong Marie Vetizou Laurence Zitvogel Marcella Occelli Carolina Cauchi Cristiana Lo Nigro Chiara Varamo Daniela Vivenza Silvia Violante Laura Lattanzio Marco Carlo Merlano Grazia Sciancalepore Giuseppe Forte Michela Rovera Zelda Seia Stefania Palazzini Fabiana Errico Davide Basso Laura Quaranta Fulvio Lavagna Paolo Bosio Duane Moogk Shi Zhong Victoria Fang Janna Dougherty Arianne Perez-Garcia Iman Osman Michelle Krogsgaard Zhiya Yu Nicholas P. Restifo Ivan Liadi Navin Varadarajan William Rittase Cheng Zhu Alan Frey Timea Balatoni Gabriella Liszkay Miklós Kasler Anita Moho Timea Sebestyén Anita Varga Judit Oláh Zsuzsanna Lengyel Gabriella Emri Andrea Ladányi Beatrice Polini Stefano Fogli Sara Carpi Maria Cristina Breschi Paola Nieri Barbara Pardini Alessio Naccarati Nevio Dubbini Antonella Romanini Francesca Morgese Davide Soldato Silvia Pagliaretta Riccardo Giampieri Silvia Rinaldi Mariangela Torniai Agnese Savini Azzurra Onofri Francesca Bianchi Rossana Berardi Donatella Brancorsini Anna Campanati McGill University Health Centre Cedars Cancer Centre Montreal QC Canada Dipartimento Uro-Ginecologico S.C. Oncologia Medica Uro-Ginecologica Istituto Nazionale Tumori Fondazione “G. Pascale” Napoli Italy Medical Oncology University Hospital of Parma Via Gramsci 14 43126 Parma PR Italy Anatomic Pathology Unit University Hospital of Parma Via Gramsci 14 43126 Parma PR Italy Weill Cornell Medicine Cornell University New York NY USA Department of Radiation Oncology Weill Cornell Medical College New York NY USA New York University Langone Medical Center New York NY USA Dept. of Human Oncology School of Medicine and Public Health University of Wisconsin Madison WI USA Provenance Biopharmaceuticals Carlisle MA USA Bristol-Myers Squibb Company Redwood City CA USA Department of Melanoma Medical Oncology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Hematology Center for Cancer Immune Therapy (CCIT) University Hospital Herlev Copenhagen Denmark Department of Immunology and Microbiology University of Copenhagen Copenhagen Denmark Institute of Pathology University of Bern Bern Switzerland Istituto Nazionale per lo Studio e la Cura dei Tumori “Fondazione G. Pascale” Naples Italy Dipartimento di Chirurgia “P. Valdoni” Sapienza Università di Roma Rome Italy IRCCS Pascale Naples Italy Dipartimento Melanoma Tessuti molli Muscolo-Scheletrico e Testa-Collo Oncologia Medica Melanoma Immunoterapia Oncologica e Terapie Innovative Istituto Nazionale Tumori “G. Pascale” Via M. Semmola 80131 Naples Italy Dipartimento di Medicina Sperimentale e Clinica Università degli Studi di Catanzaro “Magna Graecia” Catanzaro Italy Department of Molecular Virology Immunology and Medical Genetics The Ohio State University Comprehensive Cancer Center Columbus OH USA Department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai New York NY USA Dipartimento di Medicina Clinica e Molecolare Sapienza Università di Roma Rome

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Hematopoietic stem and progenitor cells harbor provirus with identical Gag and V3 sequences as residual plasma virus in optimally treated patients

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Journal of Virus Eradication 2015年 1卷 34-34页

作者： V.H. Terry N.T. Sebastian R. Yucha F. Taschuk L.A. McNamara A. Onafuwa-Nuga J. Riddell D. Bixby K.L. Collins Department of Internal Medicine University of Michigan Medical School Ann Arbor MI USA Cellular and Molecular Biology Graduate Program University of Michigan Medical School Ann Arbor MI USA Medical Scientist Training Program University of Michigan Medical School Ann Arbor MI USA Department of Microbiology and Immunology University of Michigan Medical School Ann Arbor MI USA

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Proceedings of the 14th annual conference of INEBRIA

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Addiction Science & Clinical Practice 2017年第1期12卷 1-24页

作者： Aisha S. Holloway Sarah Landale Laura Cariola Jennifer Ferguson Dorothy Newbury-Birch Amy Flynn John R. Knight Lon Sherritt Sion K. Harris Amy J. O’Donnell Eileen Kaner Barbara Hanratty Denise Howel Elaine McColl Ruth McGovern Stephanie Scott Elaine Stamp Ellen Lynch Amy M. Loree Steve Martino Amy C. Justice Kimberly A. Yonkers Kate Gilstead-Hayden Steven J. Ondersma Joy Scheidell Angeline Adam Jennifer McNeely Robert P. Schwartz Li-Tzy Wu Geetha Subramaniam Gaurav Sharma Anne H. Berman Karoline Kolaas Elisabeth Petersén Erik Hedman Kristina Sinadinovic Anna Thurang Sven Andréasson Ingvar Rosendahl Mikael Gajecki Preben Bendtsen Catharina Linderoth Ulrika Müssener Fredrik Spak Ida Gremyr Ann M. Mitchell Brayden N. Kameg Deborah Finnell Christine L. Savage Khadejah F. Mahmoud Benjamin C. Riordan Tamlin S. Conner Jayde A. M. Flett Damian Scarf Bonnie McRee Janice Vendetti Karen Steinberg Gallucci Kate Robaina Brendan J. Clark Kathryne D. Reed Rachel M. Hodapp Ivor Douglas Ellen L. Burnham Jacqueline Jones Laura Aagaard Paul F. Cook Brett R. Harris Jiang Yu Margaret Wolff Meighan Rogers Carolina Barbosa Brendan J. Wedehase Laura J. Dunlap Shannon G. Mitchell Kristi A. Dusek Jan Gryczynski Arethusa S. Kirk Marla T. Oros Colleen Hosler Kevin E. O’Grady Barry S. Brown Colin Angus Sidney Sherborne Duncan Gillespie Petra Meier Alan Brennan Divane de Vargas Janaina Soares Donna Castelblanco Ian Wittman Ryan P. McCormack Mirelis Gonzalez Kelly M. Doran Donna Shelley John Rotrosen Lillian Gelberg E. Jennifer Edelman Christopher J. Cutter Lynn E. Fiellin Patrick G. O’Connor David A. Fiellin Nathan B. Hansen Stephen A. Maisto Yanhong Deng James Dziura Roger Bedimo Cynthia Gibert Vincent C. Marconi David Rimland Maria C. Rodriguez-Barradas Michael S. Simberkoff Kendall J. Bryant Emma L. Giles Grant J. McGeechan Simon Coulton Nadine Hendrie Paolo Deluca Colin Drummond Sadie Boniface Amy Ramsey Harry Sumnall Luke Vale Viviana Alabani Amanda Atkinson Grant Stanley Jo Frankham Eilish Gilvarry Nicola Howe Justine Clephane David Gar Nursing Studies School of Health in Social Science The University of Edinburgh Edinburgh UK Health and Social Care Institute School of Health and Social Care Teesside University Middlesbrough Tees Valley UK School of Health and Social Care Teesside University Middlesbrough Tees Valley UK Alcohol and Public Health Team School of Health and Social Care Middlesbrough Teesside UK Department of Pediatrics Harvard Medical School Boston MA USA Center for Adolescent Substance Abuse Research Boston Children’s Hospital Boston MA USA Institute of Health and Society Newcastle University Baddiley-Clark Building Richardson Road Newcastle Upon Tyne Northumberland UK VA Connecticut Healthcare System Veterans Aging Cohort Study West Haven CT USA Department of Psychiatry Yale University School of Medicine New Haven CT USA Department of Psychiatry Yale School of Medicine VA Connecticut Healthcare New Haven CT USA Department of Psychiatry Yale School of Medicine VA Connecticut Healthcare System West Haven CT USA Yale University School of Medicine New Haven CT USA Merrill-Palmer Skillman Institute and Department of Psychiatry and Behavioral Neurosciences Wayne State University Detroit MI USA Department of Psychiatry and Behavioral Neurosciences Merrill-Palmer Skillman Institute Detroit MI USA Department of Psychiatry and Behavioral Neurosciences and Merrill-Palmer Skillman Institute Wayne State University Detroit MI USA Department of Population Health NYU School of Medicine New York NY USA Friends Research Institute Inc Baltimore MD USA Department of Psychiatry and Behavioral Sciences Department of Medicine and Duke Clinical Research Institute Duke University Medical Center Durham NC USA Center for the Clinical Trials Network National Institute on Drug Abuse National Institutes of Health Bethesda MD USA The EMMES Corporation Rockville MD USA Department of Clinical Neuroscience Center for Psychiatry Research Karolinska Institutet Stockholm Sweden

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Ryanodine受体的功能结构和调节因子

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中国细胞生物学学报 2015年第1期37卷 6-15页

作者：范娟杨瑾周鑫董治龙王李阳 MengMeng Xu 牟玉莲 Miyuki Nishi Williams Issacs 安书成 Hiroshi Takeshima Jianjie Ma 徐学红陕西师范大学生命科学学院细胞遗传及发育生物学实验室西安710062 兰州大学第二医院兰州730030 Medical Scientist Training Program Duke University Medical Center 中国农业科学院北京畜牧兽医研究所北京100093 Graduate School of Pharmaceutical Sciences Kyoto University School of Medicine Johns Hopkins University School of Medicine Ohio State University

Ryanodine受体(ryanodine receptor,Ry R)是位于细胞内内质网/肌浆网膜上的钙离子释放通道蛋白。Ry R是由四个足状结构的亚单位组成的同源四聚体,每个亚单位大于550 k Da,四聚体的总分子量超过2 MDa,是迄今发现的内质网/肌浆网膜上最大... 详细信息

Ryanodine受体(ryanodine receptor,Ry R)是位于细胞内内质网/肌浆网膜上的钙离子释放通道蛋白。Ry R是由四个足状结构的亚单位组成的同源四聚体,每个亚单位大于550 k Da,四聚体的总分子量超过2 MDa,是迄今发现的内质网/肌浆网膜上最大的离子通道。哺乳动物有三种类型的Ry R,其中Ry R1主要分布在骨骼肌中,Ry R2首先发现于心肌,Ry R3主要在脑中有较多分布。Ry R钙离子释放通道在肌肉收缩、突触传递、激素分泌、蛋白折叠和程控性凋亡以及坏死等一系列以细胞功能为基础的生理过程中起着极其重要的作用,因而近些年在医学生物学和药学应用上都有极大的进展。该文就Ry R在机体中的分布、功能结构和调节因子等进行了介绍,其蛋白调节因子二氢吡啶受体(dihydropyridine receptor,DHPR)、钙调蛋白(Calmodulin)、隐钙素(calsequestrin)、FKBP(FK506-binding protein)家族蛋白和小分子调节因子咖啡因、离子等都是Ry R复合体行使细胞生理功能必不可少的因素。

关键词： RyR 功能结构调节因子

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Glioblastoma stem cells:Molecular characteristics and therapeutic implications

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World Journal of Stem Cells 2014年第2期6卷 230-238页

作者： Nermin Sumru Bayin Aram Sandaldjian Modrek Dimitris George Placantonakis Department of Neurosurgery New York University School of Medicine Stem Cell Biology Training Program New York University School of Medicine Medical Scientist Training Program New York University School of Medicine Kimmel Center for Stem Cell Biology New York University School of Medicine Brain Tumor Center New York University School of Medicine

Glioblastoma Multiforme(GBM)is a grade IV astrocytoma,with a median survival of 14.6 *** GBM,stem-like cells,namely glioblastoma stem cells(GSCs),have the ability to self-renew,differentiate into distinct lineages within the tumor and initiate tumor xenografts in immunocompromised animal *** importantly,GSCs utilize cell-autonomous and tumor microenvironment-mediated mechanisms to overcome current therapeutic *** are,therefore,very important therapeutic *** the functional criteria defining GSCs are well defined,their molecular characteristics,the mechanisms whereby they establish the cellular hierarchy within tumors,and their contribution to tumor heterogeneity are not well *** review is aimed at summarizing current findings about GSCs and their therapeutic importance from a molecular and cellular point of view.A better characterization of GSCs is crucial for designing effective GSCtargeted therapies.

关键词： Glioblastoma Glioblastoma stem cells Selfrenewal Differentiation Molecular markers Therapy resistance

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XXIV World Allergy Congress 2015 Seoul, Korea. 14-17 October 2015 Abstracts

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WORLD ALLERGY ORGANIZATION JOURNAL 2016年第1期9卷 1-206页

作者： [Anonymous] Korea University College of Medicine Guro Hospital Seoul South Korea College of Medicine Korea University Seoul South Korea Korea University Guro Hospital Seoul South Korea Seoul National University Boramae Hospital Seoul South Korea Division of Clinical Immunology Faculty of Medicine University of Debrecen Debrecen Hungary Meiji Pharmaceutical University Tokyo Japan Suri Medical Foundation Hospital Uttar Pradesh State India Shahid Beheshti University Tehran Iran Airlangga University Teaching Hospital Surabaya Indonesia Tokyo Metropolitan Police Hospital Tokyo Japan Shinichiro KogaSamsung Changwon Hospital Seoul South Korea Sapporo Tokushukai Hospital Sapporo Japan Department of Dermatology Yonsei University College of Medicine Seoul South Korea Brain Korea 21 PLUS Project for Medical Science Yonsei University College of Medicine Seoul South Korea Sureyyapasa Chest Diseases and Chest Surgery Training Hospital Istanbul Turkey Kangnam Sacred Heart Hospital Seoul South Korea Sakai City Medical Center Sakai Japan Osaka University Suita Japan Yonsei University College of Medicine Seoul South Korea Osaka-Minami Medical Center Kawachinagano Japan Inha University College of Medicine Incheon South Korea Inha University Hospital Incheon South Korea Center for Rhinology and Allergology Wiesbaden Wiesbaden Germany Leti Pharma Gmbh Witten Germany Postgraduate Institute of Medical Education and Research Chandigarh India West Bengal Technical University Kolkata India Institute of Microbiology Academy of Sciences of the Czech Republic Prague Czech Republic Seoul National University Hospital Seoul South Korea Ent and Allergy Centre(INDIA) Panchkula India University of Santo Tomas Hospital Manila Philippines University of Santo Tomas Faculty of Medicine Manila Philippines Kyung Hee University Hospital at Gang-Dong Seoul South Korea Sangji University Wonju South Korea Division of Allergy and Immunology Department of Internal Medicine Yonsei University Colle

A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendritic cells Katsuhiko Matsui, Saki Tamai, Reiko Ikeda A5 An evaluation of variousallergens in cases of allergic bronchial asthma at lucknow and neighbouring districts by intradermal skintest Drsushil Suri, Dranu Suri A6 Evaluation ferqency of ADHD in childhood asthma Marzieh Heidarzadeh Arani A7 Steven johnson syndrome caused by typhoid fever in a child Azwin Lubis, Anang Endaryanto A8 Chronic Bronchitis with Radio Contrast Media Hypersensitivity: A Case with Hypothesized GINA Step 1 Asthma Shinichiro Koga A9 The association between asthma and depression in Korean adult : An analysis of the fifth korea national health and nutrition examination survey (2010-2012) Lee Ju Suk A10 Management of allergic disease exacerbations in pregnancy Yasunobu Tsuzuki A11 Subcutaneous immunotherapy mouse model for atopic dermatitis Seo Hyeong Kim, Jung U Shin, Ji Yeon Noh, Shan Jin, Shan Jin, Hemin Lee, Jungsoo Lee, Chang Ook Park, Kwang Hoon Lee, Kwang Hoon Lee A12 Atopic disease and/or atopy are risk factors for local anesthetic allergy in patients with history of hypersensitivity reactions to drugs? Fatma Merve Tepetam A13 Food hypersensitivity in patients with atopic dermatitis in Korea Chun Wook Park, Jee Hee Son, Soo Ick Cho, Yong Se Cho, Yun Sun Byun, Yoon Seok Yang, Bo Young Chung, Hye One Kim, Hee Jin Cho A14 Anaphylaxis caused by an ant (Brachyponera chinensis) in Japan Yoshinori Katada, Toshio Tanaka, Akihiko Nakabayashi, Koji Nishida, Kenichi A

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Corrigendum to "Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation"

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American journal of medical genetics. Part A 2015年第10期167A卷 2496页

作者： Mark N Ziats Matthew S Comeaux Yaping Yang Fernando Scaglia Sarah H Elsea Qin Sun Arthur L Beaudet Christian P Schaaf Medical Scientist Training Program Baylor College of Medicine Houston Texas. Molecular and Human Genetics Baylor College of Medicine Houston Texas. Jan and Dan Duncan Neurological Research Institute Texas Children's Hospital Houston Texas.

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The relationship between intracranial vascular health and metrics of Alzheimer's disease

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Alzheimer's & Dementia 2015年第7期11卷 P793-P794页

作者： Sara Elizabeth Berman Leonardo Rivera Oliver Wieben Annie M. Racine Lindsay R. Clark Cynthia M. Carlsson Barbara B. Bendlin Lisa C. Bratzke Howard A. Rowley Patrick Turski Henrik Zetterberg Kaj Blennow Sanjay Asthana Sterling C. Johnson University of Wisconsin School of Medicine and Public Health Medical Scientist Training Program Madison WI USA University of Wisconsin-Madison Neuroscience Training Program Madison WI USA Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health Madison WI USA Wisconsin Alzheimer's Institute University of Wisconsin School of Medicine and Public Health Madison WI USA University of Wisconsin-Madison Madison WI USA Neuroscience Training Program University of Wisconsin Madison WI USA Neuroscience and Public Policy Program University of Wisconsin Madison WI USA Geriatric Research Education and Clinical Center Wm. S. Middleton Veterans Hospital Madison WI USA School of Nursing University of Wisconsin School of Medicine and Public Health Madison WI USA University of Wisconsin School of Medicine and Public Health Madison WI USA Clinical Neurochemistry Laboratory Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden UCL Institute of Neurology London United Kingdom Waisman Laboratory for Brain Imaging and Behavior University of Wisconsin-Madison Madison WI USA

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Editorial Commentary: Preventing Malaria in HIV-Infected Pregnant Women

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Clinical Infectious Diseases 2014年第5期58卷 660-662页

作者： Bulterys, Philip L. Kaplan, Jonathan E. Gutman, Julie UCLA-Caltech Medical Scientist Training Program David Geffen School of Medicine University of California Los Angeles Division of Global HIV/AIDS Division of Parasitic Diseases and Malaria Center for Global Health Centers for Disease Control and Prevention Atlanta Georgia

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EFFECTS OF KIBRA POLYMORPHISM ON WHITE MATTER INTEGRITY: FINDINGS FROM THE WISCONSIN REGISTRY FOR ALZHEIMER’S PREVENTION

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Alzheimer's & Dementia 2016年第7期12卷 P54-P55页

作者： Karly Alex Cody Andrew P. Merluzzi Jennifer M. Oh Annie M. Racine Stephanie A. Schultz Elizabeth A. Boots Douglas C. Dean Hui Zhang Nagesh Adluru Catherine L. Gallagher Cynthia M. Carlsson Bruce P. Hermann Howard A. Rowley Sanjay Asthana Mark A. Sager Sterling C. Johnson Andrew L. Alexander Barbara B. Bendlin Ozioma C. Okonkwo Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health Madison WI USA Neuroscience Training Program University of Wisconsin Madison WI USA Waisman Laboratory for Brain Imaging and Behavior University of Wisconsin-Madison Madison WI USA University College London London United Kingdom Alzheimer's Disease Research Center Madison WI USA Geriatric Research Education and Clinical Center Wm. S. Middleton Veterans Hospital Madison WI USA Wisconsin Alzheimer's Institute University of Wisconsin School of Medicine and Public Health Madison WI USA University of Wisconsin School of Medicine and Public Health Madison WI USA Department of Medical Physics University of Wisconsin - Madison Madison WI USA

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