检索结果-内蒙古大学图书馆

CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia

引用

BLOOD 2017年 130卷 560-560页

作者： Chang, Yunchao Woessner, David W. Lin, Wenwei Chen, Taosheng Xu, Beisi Fan, Yiping Tan, Haiyan Peng, Junmin Kasper, Lawryn Churchman, Michelle L. Loh, Mignon L. Hunger, Stephen P. Seth, Aman Gascoigne, Karen Brindle, Paul K. Mullighan, Charles G. Department of Pathology St. Jude Children's Research Hospital Memphis TN Department of Chemical Biology and Therapeutics St. Jude Children's Research Hospital Memphis TN Department of Computational Biology St. Jude Children's Research Hospital Memphis TN Proteomics St. Jude Children's Research Hospital Memphis TN Department of Structural Biology St. Jude Children's Research Hospital Memphis TN Department of Developmental Neurobiology St. Jude Children's Research Hospital Memphis TN Department of Pediatrics Benioff Children's Hospital and the Helen Diller Family Comprehensive Cancer Center University of California at San Francisco San Francisco CA Division of Oncology and the Center for Childhood Cancer Research Children's Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania Philadelphia PA Hematological Malignancies Program St. Jude Children's Research Hospital Memphis TN Department of Discovery Oncology Genentech Inc. South San Francisco CA Department of Biochemistry St. Jude Children's Research Hospital Memphis TN

560

关键词：

来源：评论

学校读者我要写书评

暂无评论

Modeling Protein Structure in Macromolecular Assemblies at Near Atomic Resolutions

引用

Microscopy and Microanalysis 2015年第S3期21卷 541-542页

作者： Matthew L. Baker Muyuan Chen Philip R. Baldwin Steven J. Ludtke Wah Chiu National Center for Macromolecular Imaging Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston TXUSA Program in Structural and Computational Biology Baylor College of Medicine Houston TXUSA

来源：评论

学校读者我要写书评

暂无评论

structural basis of cyclic nucleotide selectivity in cGMP dependent protein kinase II

引用

BMC Pharmacology and Toxicology 2015年第1期16卷 1-2页

作者： James C. Campbell John E. Ladbury Choel Kim Kevin Y. Li Jeong Joo Kim Albert S. Reger Gilbert Huang Shinya Matsuda Keizo Yuasa Banumathi Sankaran Todd M. Link Structural and Computational Biology and Molecular Biophysics Program Baylor College of Medicine Houston Texas USA Department of Biochemistry and Molecular Biology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Pharmacology Baylor College of Medicine Houston Texas USA Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston Texas USA Department of Biochemistry & Cell Biology Rice University Houston USA Department of Biological Science and Technology The University of Tokushima Graduate School Tokushima 770-8506 Japan Berkeley Center for Structural Biology Lawrence Berkeley National Laboratory Berkeley California USA

来源：评论

学校读者我要写书评

暂无评论

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

引用

BMC pharmacology & toxicology 2017年第SUPPL 1期18卷 64-64页

作者： Todd Milne, G. Sandner, Peter Lincoln, Kathleen A. Harrison, Paul C. Chen, Hongxing Wang, Hong Clifford, Holly Qian, Hu Sheng Wong, Diane Sarko, Chris Fryer, Ryan Richman, Jeremy Reinhart, Glenn A. Boustany, Carine M. Pullen, Steven S. Andresen, Henriette Moltzau, Lise Román Cataliotti, Alessandro Levy, Finn Olav Lukowski, Robert Frankenreiter, Sandra Friebe, Andreas Calamaras, Timothy Baumgartner, Robert McLaughlin, Angela Aronovitz, Mark Baur, Wendy Wang, Guang-Rong Kapur, Navin Karas, Richard Blanton, Robert Hell, Stefan Waldman, Scott A. Lin, Jieru E. Colon-Gonzalez, Francheska Kim, Gilbert W. Blomain, Erik S. Merlino, Dante Snook, Adam Erdmann, Jeanette Wobst, Jana Kessler, Thorsten Schunkert, Heribert Walter, Ulrich Pagel, Oliver Walter, Elena Gambaryan, Stepan Smolenski, Albert Jurk, Kerstin Zahedi, Rene Klinger, James R. Benza, Raymond L. Corris, Paul A. Langleben, David Naeije, Robert Simonneau, Gérald Meier, Christian Colorado, Pablo Chang, Mi Kyung Busse, Dennis Hoeper, Marius M. Masferrer, Jaime L. Jacobson, Sarah Liu, Guang Sarno, Renee Bernier, Sylvie Zhang, Ping Flores-Costa, Roger Currie, Mark Hall, Katherine Möhrle, Dorit Reimann, Katrin Wolter, Steffen Wolters, Markus Mergia, Evanthia Eichert, Nicole Geisler, Hyun-Soon Ruth, Peter Feil, Robert Zimmermann, Ulrike Koesling, Doris Knipper, Marlies Rüttiger, Lukas Tanaka, Yasutake Okamoto, Atsuko Nojiri, Takashi Kumazoe, Motofumi Tokudome, Takeshi Miura, Koichi Hino, Jun Hosoda, Hiroshi Miyazato, Mikiya Kangawa, Kenji Kapil, Vikas Ahluwalia, Amrita Paolocci, Nazareno Eaton, Philip Campbell, James C. Henning, Philipp Franz, Eugen Sankaran, Banumathi Herberg, Friedrich W. Kim, Choel Wittwer, M. Luo, Q. Kaila, V. Dames, S. A. Tobin, Andrew Alam, Mahmood Rudyk, Olena Krasemann, Susanne Hartmann, Kristin Prysyazhna, Oleksandra Zhang, Min Zhao, Lan Weiss, Astrid Schermuly, Ralph Moyes, Amie J. Chu, Sandy M. Baliga, Reshma S. Hobbs, Adrian J. Michalakis, Stylianos Mühlfriedel, Regine Schön, Christian Fischer, Dominik M. Wilhelm, Barbara Zobor, Ditta Kohl, Ironwood Pharmaceuticals Cambridge USA Bayer AG Drug Discovery - Cardiovascular Research Wuppertal Germany Department of Cardiometabolic Diseases Research Boehringer Ingelheim Pharmaceuticals Ridgefield USA Department of Small Molecule Drug Research Boehringer Ingelheim Pharmaceuticals Ridgefield USA Department of Pharmacology University of Oslo and Oslo University Hospital Oslo Norway Institute of Experimental Medical Research University of Oslo and Oslo University Hospital Oslo Norway Center for Heart Failure Research University of Oslo and Oslo University Hospital Oslo Norway Department of Pharmacology Toxicology and Clinical Pharmacy Institute of Pharmacy University of Tuebingen Tuebingen Germany Physiologisches Institut Universität Würzburg Würzburg Germany Molecular Cardiology Research Institute Tufts Medical Center Boston USA Present Affiliation: Division of Cardiology University of Pittsburgh Medical Center Pittsburgh USA Present Affiliation: Department of Medicine Brown University School of Medicine Providence USA Division of Cardiology Tufts Medical Center Boston USA Max Planck Institute for Biophysical Chemistry Göttingen and German Cancer Research Center (DKFZ) Heidelberg Germany Department of Pharmacology and Experimental Therapeutics Thomas Jefferson University Philadelphia USA Institut für Kardiogenetik and Universitäres Herzzentrum Lübeck Universität zu Lübeck Lübeck Germany & DZHK e.V. (German Center for Cardiovascular Research) Partner Site Hamburg/Kiel/Lübeck Lübeck Germany Deutsches Herzzentrum München Klinik für Herz- und Kreislauferkrankungen Technische Universität München Munich Germany Center for Thrombosis & Hemostasis Universitätsklinikum der Johannes Gutenberg-Universität Mainz Mainz Germany Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V Dortmund Germany Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences St. Petersburg Russia UCD Conway Institute UCD School of Medicine

来源：评论

学校读者我要写书评

暂无评论

Erratum to: Somatic Mosaicism: Implications for Disease and Transmission Genetics

引用

Trends in genetics : TIG 2016年第2期32卷 138页

作者： Ian M Campbell Chad A Shaw Pawel Stankiewicz James R Lupski Department of Molecular and Human Genetics Baylor College of Medicine Houston TX 77030 USA. Department of Molecular and Human Genetics Baylor College of Medicine Houston TX 77030 USA Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine Houston TX 77030 USA Department of Statistics Rice University Houston TX 77005. Department of Pediatrics Baylor College of Medicine Houston TX 77030 USA Texas Children's Hospital Houston TX 77030 USA Human Genome Sequencing Center Baylor College of Medicine Houston TX 77030 USA.

来源：评论

学校读者我要写书评

暂无评论

Seeing the Portal in Membrane-containing Bacteriophage PRD1 by Cryo-EM

引用

Microscopy and Microanalysis 2014年第S3期20卷 1250-1251页

作者： Chuan Hong Xiangan Liu Hanna M. Oksanen Joanita Jakana Dennis H. Bamford Wah Chiu Graduate Program in Structural and Computational Biology and Molecular Biophysics Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston TX 77030 USA Institute of Biotechnology and Department of Biosciences University of Helsinki FIN-00014 Helsinki Finland

来源：评论

学校读者我要写书评

暂无评论

Visualizing Virus Assembly Intermediates Inside Marine Cyanobacteria by Zernike Phase Contrast Electron Cryo-Tomography

引用

Microscopy and Microanalysis 2014年第S3期20卷 202-203页

作者： Chiu, Wah Dai, Wei Fu, Caroline Raytcheva, Desislava Flanagan, John Khant, Htet A Liu, Xiangan Rochat, Ryan H Haase-Pettingell, Cameron Piret, Jacqueline Ludtke, Steve J Nagayama, Kuniaki Schmid, Michael F King, Jonathan A National Center for Macromolecular Imaging Verna and Marrs Mclean Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston TX USA Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine Houston TX USA Department of Biology Massachusetts Institute of Technology Cambridge MA USA Department of Biology Northeastern University Boston MA USA National Institute for Physiological Sciences National Institutes of Natural Sciences 5-1 Higashiyama Myodaiji Okazaki Japan

来源：评论

学校读者我要写书评

暂无评论

EMAN2.1 - A New Generation of Software for Validated Single Particle Analysis and Single Particle Tomography

引用

Microscopy and Microanalysis 2014年第S3期20卷 832-833页

作者： SC Murray JG Galaz-Montoya G Tang JF Flanagan SJ Ludtke Graduate Program in Structural and Computational Biology & Molecular Biophysics Baylor College of Medicine One Baylor Plaza Houston TX 77025 National Center for Macromolecular Imaging Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine One Baylor Plaza Houston TX 77025 Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine One Baylor Plaza Houston TX 77025

来源：评论

学校读者我要写书评

暂无评论

11th German Conference on Chemoinformatics (GCC 2015) Abstracts

引用

JOURNAL OF CHEMINFORMATICS 2016年第SUPPL 1期8卷 1-27页

作者： [Anonymous] GDCh-CIC Division Associated Board Member Beilstein-Institut zur Förderung der Chemischen Wissenschaften Trakehner Str. 7-9 60487 Frankfurt Germany. ufechner@beilstein-institut.de. Division Medicinal Chemistry Amsterdam Institute for Molecules Medicines and Systems (AIMMS) VU University Amsterdam The Netherlands. Centre for Bioinformatics Uni Hamburg Bundesstr. 43 20146 Hamburg Germany. Sanofi-Aventis Deutschland GmbH 65926 Frankfurt am Main Germany. stefan.guessregen@***. Sanofi-Aventis Deutschland GmbH 65926 Frankfurt am Main Germany. GlaxoSmithKline Stevenage SG1 2NY UK. nicola.j.richmond@***. Discngine Paris 75011 France. Organisch-Chemisches Institut Westfälische Wilhelms-Universität Münster Germany. marwin.segler@wwu.de. Organisch-Chemisches Institut Westfälische Wilhelms-Universität Münster Germany. Bundeskriminalamt Wiesbaden Central Analytics II 65173 Wiesbaden Germany. Department of Chemistry and Biochemistry University of California Santa Barbara CA 93111 USA. shea@chem.ucsb.edu. Department of Chemistry and Biochemistry University of California Santa Barbara CA 93111 USA. Chemistry Department Ludwig-Maximilians-Universität München Butenandtstr. 7 81377 Munich Germany. Inorganic Chemistry and Center for Nanointegration University of Duisburg-Essen Essen Germany. CAM-D Technologies Essen Germany. Institute for Bioinformatics and Chemoinformatics Westphalian University of Applied Sciences Recklinghausen Germany. Institute for Bioinformatics and Chemoinformatics Westphalian University of Applied Sciences Recklinghausen Germany. achim.zielesny@w-hs.de. Leiden University Leiden Netherlands. j.fraaije@chem.leidenuniv.nl. Culgi BV Berlin Germany. Physikalische Chemie III TU Dortmund 44227 Dortmund Germany. stefan.kast@tu-dortmund.de. Centre for Molecular Informatics Department of Chemistry University of Cambridge Lensfield Road Cambridge CB2 1EW United Kingdom. kcb27@cam.ac.uk. Centre for Molecular Informatics Department of Chemistry

来源：评论

学校读者我要写书评

暂无评论

Origin of Overstretching Transitions in Single-Stranded Nucleic Acids

引用

Physical Review Letters 2013年第18期111卷 188302-188302页

作者： Zackary N. Scholl Mahir Rabbi David Lee Laura Manson Hanna S-Gracz Piotr E. Marszalek Program in Computational Biology and Bioinformatics Duke University Durham North Carolina 27708 USA Department of Mechanical Engineering and Materials Science Center for Biologically Inspired Materials and Material Systems Duke University Durham North Carolina 27708 USA Department of Molecular and Structural Biochemistry North Carolina State University Raleigh North Carolina 27708 USA

We combined single-molecule force spectroscopy with nuclear magnetic resonance measurements and molecular mechanics simulations to examine overstretching transitions in single-stranded nucleic acids. In single-stranded DNA and single-stranded RNA there is a low-force transition that involves unwinding of the helical structure, along with base unstacking. We determined that the high-force transition that occurs in polydeoxyadenylic acid single-stranded DNA is caused by the cooperative forced flipping of the dihedral angle formed between four atoms, O5’-C5’-C4’-C3’ (γ torsion), in the nucleic acid backbone within the canonical B-type helix. The γ torsion also flips under force in A-type helices, where the helix is shorter and wider as compared to the B-type helix, but this transition is less cooperative than in the B type and does not generate a high-force plateau in the force spectrums of A-type helices. We find that a similar high-force transition can be induced in polyadenylic acid single-stranded RNA by urea, presumably due to disrupting the intramolecular hydrogen bonding in the backbone. We hypothesize that a pronounced high-force transition observed for B-type helices of double stranded DNA also involves a cooperative flip of the γ torsion. These observations suggest new fundamental relationships between the canonical structures of single-and double-stranded DNA and the mechanism of their molecular elasticity.

关键词： NUCLEAR magnetic resonance spectroscopy SINGLE-stranded DNA NUCLEOTIDE sequence DEOXYRIBOSE ATOMIC force microscopy

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：