咨询与建议

限定检索结果

文献类型

  • 241 篇 期刊文献
  • 22 篇 会议

馆藏范围

  • 263 篇 电子文献
  • 0 种 纸本馆藏

日期分布

学科分类号

  • 185 篇 理学
    • 114 篇 生物学
    • 59 篇 化学
    • 26 篇 物理学
    • 15 篇 数学
    • 9 篇 统计学(可授理学、...
    • 2 篇 天文学
    • 2 篇 系统科学
  • 141 篇 工学
    • 46 篇 化学工程与技术
    • 38 篇 生物工程
    • 33 篇 生物医学工程(可授...
    • 26 篇 计算机科学与技术...
    • 18 篇 软件工程
    • 7 篇 光学工程
    • 5 篇 材料科学与工程(可...
    • 4 篇 电子科学与技术(可...
    • 3 篇 机械工程
    • 3 篇 动力工程及工程热...
    • 3 篇 信息与通信工程
    • 3 篇 航空宇航科学与技...
    • 2 篇 力学(可授工学、理...
    • 2 篇 仪器科学与技术
    • 2 篇 电气工程
    • 2 篇 控制科学与工程
    • 2 篇 环境科学与工程(可...
  • 58 篇 医学
    • 43 篇 基础医学(可授医学...
    • 29 篇 临床医学
    • 16 篇 药学(可授医学、理...
    • 7 篇 公共卫生与预防医...
  • 43 篇 农学
    • 28 篇 作物学
  • 10 篇 管理学
    • 5 篇 管理科学与工程(可...
  • 1 篇 教育学

主题

  • 14 篇 proteins
  • 7 篇 computational bi...
  • 7 篇 rna
  • 6 篇 machine learning
  • 5 篇 dna
  • 5 篇 amino acids
  • 4 篇 bioinformatics
  • 4 篇 molecular dynami...
  • 3 篇 protein engineer...
  • 3 篇 x ray crystallog...
  • 3 篇 structural genom...
  • 3 篇 single-molecule ...
  • 3 篇 mass spectrometr...
  • 3 篇 protein structur...
  • 2 篇 biology computin...
  • 2 篇 lc-ms/ms
  • 2 篇 molecular struct...
  • 2 篇 cancer
  • 2 篇 protein design
  • 2 篇 structure determ...

机构

  • 10 篇 department of in...
  • 7 篇 department of mo...
  • 6 篇 national institu...
  • 6 篇 division of card...
  • 6 篇 department of tw...
  • 6 篇 university of gl...
  • 6 篇 department of mo...
  • 5 篇 atherogenomics l...
  • 5 篇 leeds institute ...
  • 5 篇 center for psych...
  • 5 篇 institute for pa...
  • 5 篇 department of st...
  • 5 篇 university of pi...
  • 5 篇 arnie charbonnea...
  • 5 篇 institute for ca...
  • 5 篇 ilsbio llc bioba...
  • 5 篇 broad genomics b...
  • 5 篇 framingham heart...
  • 5 篇 faculty of biosc...
  • 5 篇 osaka internatio...

作者

  • 7 篇 mark gerstein
  • 6 篇 gerstein mark
  • 6 篇 wah chiu
  • 5 篇 steven j. ludtke
  • 5 篇 eleftheria zeggi...
  • 5 篇 macarthur daniel...
  • 5 篇 warrell jonathan
  • 5 篇 daly mark j.
  • 5 篇 gerstein mark b.
  • 5 篇 alfoldi jessica
  • 5 篇 yingxiao wang
  • 5 篇 karczewski konra...
  • 5 篇 jihye seong
  • 4 篇 timothy m frayli...
  • 4 篇 danish saleheen
  • 4 篇 andrew t hatters...
  • 4 篇 terho lehtimäki
  • 4 篇 andrew r wood
  • 4 篇 veronique vitart
  • 4 篇 caroline hayward

语言

  • 254 篇 英文
  • 4 篇 其他
  • 4 篇 中文
检索条件"机构=Program in Structural and Computational Biology and Molecular Biophysics"
263 条 记 录,以下是31-40 订阅
排序:
Nucleic acids and molecular biology volume 9
收藏 引用
Chemistry & biology 1996年 第9期3卷 729-730页
作者: Mair E.A. Churchill Department of Cell and Structural Biology Program in Biophysics and Computational Biology and Biochemistry Department University of Illinois at Urbana-Champaign Urbana IL 61801 USA
来源: 评论
Seeing the Portal in Membrane-containing Bacteriophage PRD1 by Cryo-EM
收藏 引用
Microscopy and Microanalysis 2014年 第S3期20卷 1250-1251页
作者: Chuan Hong Xiangan Liu Hanna M. Oksanen Joanita Jakana Dennis H. Bamford Wah Chiu Graduate Program in Structural and Computational Biology and Molecular Biophysics Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston TX 77030 USA Institute of Biotechnology and Department of Biosciences University of Helsinki FIN-00014 Helsinki Finland
来源: 评论
Gorgon and pathwalking: Macromolecular modeling tools for subnanometer resolution density maps
Gorgon and pathwalking: Macromolecular modeling tools for su...
收藏 引用
作者: Baker, Matthew L. Baker, Mariah R. Hryc, Corey F. Ju, Tao Chiu, Wah Verna and Marrs McLean Department of Biochemistry and Molecular Biology National Center for Macromolecular Imaging Baylor College of Medicine Houston TX 77030 United States Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine Houston TX 77030 United States Department of Computer Science and Engineering Washington University in St. Louis St. Louis MO 63130 United States
The complex interplay of proteins and other molecules, often in the form of large transitory assemblies, are critical to cellular function. Today, X-ray crystallography and electron cryo-microscopy (cryo-EM) are routi... 详细信息
来源: 评论
Sorbate induces lysine sorbylation through noncanonical activities of class I HDACs to regulate the expression of inflammation genes
收藏 引用
Science Advances 2025年 第22期11卷
作者: Yi-Cheng Sin Breann Abernathy Zuo-fei Yuan Jason L. Heier Justin E. Gonzalez Laurie L. Parker Douglas G. Mashek Yue Chen Department of Biochemistry Molecular Biology and Biophysics University of Minnesota Twin Cities Minneapolis MN USA. Bioinformatics and Computational Biology Program University of Minnesota Twin Cities Minneapolis MN USA. Center for Proteomics and Metabolomics St. Jude Children’s Research Hospital Memphis TN USA. Department of Medicine Division of Diabetes Endocrinology and Metabolism University of Minnesota Twin Cities Minneapolis MN USA. Institute for the Biology of Aging and Metabolism University of Minnesota Twin Cities Minneapolis MN USA.
Environmental factors may affect gene expression through epigenetic modifications of histones and transcription factors. Here, we report that cellular uptake of sorbate, a common food preservative, induces lysine sorb...
来源: 评论
Enhanced expression of β3-galactosyltransferase 5 activity is sufficient to induce in vivo synthesis of extended type 1 chains on lactosylceramides of selected human colonic carcinoma cell lines
收藏 引用
Glycobiology 2009年 第4期19卷 418-427页
作者: Lin, Chi-Hung Fan, Yao-Yun Chen, Yen-Ying Wang, Shih-Hsin Chen, Chun-I Yu, Lung-Chih Khoo, Kay-Hooi Chemical Biology and Molecular Biophysics Program Taiwan International Graduate Program Academia Sinica Taipei 115 Taiwan Institute of Bioinformatics and Structural Biology National Tsing-Hua University Hsinchu 300 Taiwan Institute of Biological Chemistry Academia Sinica Nankang Taipei 115 Taiwan Taiwan and Institute of Biochemical Science National Taiwan University Taipei 106 Taiwan
In general, an elevated expression of β3-galactosyltrans-ferase (β3GalT) activity contributed by β3GalT5 correlates well with increased biosynthesis and expression of type 1 chain (Galβ1-3GlcNAcβ1-) derivatives s... 详细信息
来源: 评论
Building and Validating Atomic Models for Cryo-EM Density Maps
收藏 引用
Microscopy and Microanalysis 2016年 第S3期22卷 2080-2081页
作者: Matthew L. Baker Muyuan Chen Tunay Durmaz Phil Baldwin Tao Ju Steven J. Ludtke Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine HoustonTXUSA Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine HoustonTXUSA Department of Computer Science and Engineering Washington University in St. Louis St. LouisMOUSA
来源: 评论
Cryo-FIB Lamella Milling: A Comprehensive Technique to Prepare Samples of Both Plunge- and High-pressure Frozen-hydrated Specimens for in situ Studies.
收藏 引用
Microscopy and Microanalysis 2018年 第S1期24卷 820-821页
作者: Miroslava Schaffer Stefan Pfeffer Stephan Kleindiek Julia Mahamid Michael Heymann Andrew J. Smith Tim Laugks Benjamin D. Engel Sahradha Albert Wolfgang Baumeister Max Planck Institute of Biochemistry Dep. of Molecular Structural Biology Martinsried Germany Kleindiek Nanotechnik GmbH Markwiesenstraße 55 Reutlingen Germany Structural and Computational Biology Unit European Molecular Biology Laboratory Heidelberg Max Planck Institute of Biochemistry Dep. of Cellular and Molecular Biophysics Martinsried Germany
来源: 评论
New Strategies for Improving CryoEM Single Particle Analysis in EMAN2.2
收藏 引用
Microscopy and Microanalysis 2017年 第S1期23卷 810-811页
作者: Steven J. Ludtke Tunay Durmaz Muyuan Chen James M. Bell Verna and Marrs McLean Dept. of Biochemistry Baylor College of Medicine Houston TX USA. Graduate Program in Structural and Computational Biology & Molecular Biophysics Baylor College of Medicine Houston TX USA.
来源: 评论
Recognition of self and altered self by T cells in autoimmunity and allergy
收藏 引用
Protein & Cell 2013年 第1期4卷 8-16页
作者: Lei Yin Shaodong Dai Gina Clayton Wei Gao Yang Wang John Kappler Philippa Marrack Howard Hughes Medical Institute and Integrated Department of Immunology National Jewish HealthDenverCO 80206USA Integrated Department of Immunology National Jewish HealthDenverCO80206USA Program in Structural Biology and Biophysics University of Colorado DenverSchool of MedicineAuroraCO 80045USA Department of Biochemistry and Molecular Genetics University of Colorado DenverSchool of MedicineAuroraCO 80045USA
T cell recognition of foreign peptide antigen and toler-ance to self peptides is key to the proper function of the immune ***,in the thymus T cells that rec-ognize self MHC+self peptides are deleted and those with the... 详细信息
来源: 评论
Detection of virus particles in noisy spot-scan electron cryomicroscopy images
Detection of virus particles in noisy spot-scan electron cry...
收藏 引用
IEEE International Conference on Image Processing
作者: P. Thuman-Commike W. Chiu Program in Structural and Computational Biology and Molecular Biophysics Verna and Marrs McLean Department of Biochemistry The W. M. Keck Center for Computation Biology Baylor University College of Medicine Houston TX USA
We present a method to identify and extract virus particle images from noisy spot-scan electron cryomicroscopy images. We use a template matching algorithm to identify virus particles. Due to the high spatial variatio... 详细信息
来源: 评论