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检索条件"机构=Program in Structural and Computational Biology and Molecular Biophysics"
263 条 记 录,以下是71-80 订阅
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structural basis of cyclic nucleotide selectivity in cGMP dependent protein kinase II
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BMC Pharmacology and Toxicology 2015年 第1期16卷 1-2页
作者: James C. Campbell John E. Ladbury Choel Kim Kevin Y. Li Jeong Joo Kim Albert S. Reger Gilbert Huang Shinya Matsuda Keizo Yuasa Banumathi Sankaran Todd M. Link Structural and Computational Biology and Molecular Biophysics Program Baylor College of Medicine Houston Texas USA Department of Biochemistry and Molecular Biology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Pharmacology Baylor College of Medicine Houston Texas USA Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston Texas USA Department of Biochemistry & Cell Biology Rice University Houston USA Department of Biological Science and Technology The University of Tokushima Graduate School Tokushima 770-8506 Japan Berkeley Center for Structural Biology Lawrence Berkeley National Laboratory Berkeley California USA
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Characterization of the retinal proteome during rod photoreceptor genesis
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BMC Research Notes 2010年 第1期3卷 1-8页
作者: Barnhill, Alison E Hecker, Laura A Kohutyuk, Oksana Buss, Janice E Honavar, Vasant G Greenlee, Heather West Interdepartmental Neuroscience Program Iowa State University Ames IA United States Department of Biomedical Sciences Iowa State University Ames IA United States Bioinformatics and Computational Biology Program Iowa State University Ames IA United States Department of Biochemistry Biophysics and Molecular Biology Iowa State University Ames IA United States Department of Computer Science Iowa State University Ames IA United States National Animal Disease Center Ames IA 50010 United States Mayo Clinic Department of Ophthalmology Rochester MN 55905 United States
Background. The process of rod photoreceptor genesis, cell fate determination and differentiation is complex and multi-factorial. Previous studies have defined a model of photoreceptor differentiation that relies on i... 详细信息
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EXPERIMENTAL AND THEORETICAL STUDIES OF HYDROGEN BONDS IN FE-S PROTEINS
EXPERIMENTAL AND THEORETICAL STUDIES OF HYDROGEN BONDS IN FE...
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第十二届北京分析测试学术报告会暨展览会(BCEIA 2007)
作者: William M.WESTLER I-Jin LIN Erika B.GEBEL Timothy E.MACHONKIN Bin XIA John L.MARKLEY National Magnetic Resonance Facility at Madison University of Wisconsin-Madison Department of Biochemistry University of Wisconsin-Madison Graduate Program in Biophysics University of Wisconsin-Madison Program in Molecular and Computational Biophysics Johns Hopkins University Department of Chemical Biology College of Life Sciences Peking University
Iron-sulfur proteins are ubiquitous and essential to *** addition to their functional roles as electron transport proteins in photosynthesis and respiration,iron-sulfur proteins also are involved in nitrogen fixation,... 详细信息
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Comparison of experimental and computed protein anisotropic temperature factors
Comparison of experimental and computed protein anisotropic ...
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IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)
作者: Lei Yang Guang Song Robert L. Jernigan Program of Bioinformatics and Computational Biology Department of Biochemistry Biophysics and Molecular Biology Iowa State University Ames IA USA Department of Computer Science Iowa State University Ames IA USA Department of Biochemistry Biophysics and Molecular Biology L. H. Baker Center for Bioinformatics and Biological Statistics Iowa State University Ames IA USA
Because of its appealing simplicity, the anisotropic network model (ANM) has been widely accepted and applied to study many molecular motion problems: such as the molecular mechanisms of GroEL-GroES function, alloster... 详细信息
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From mechanism to medicine: The progress and potential of epigenetics in osteoarthritis
Osteoarthritis and Cartilage Open
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Osteoarthritis and Cartilage Open 2025年 第3期7卷 100621-100621页
作者: Roberts, Jack B. Rockel, Jason S. Mulders, Rick Capellini, Terence D. Appleton, C. Thomas Phanstiel, Douglas H. Lories, Rik Geurts, Jeroen Ali, Shabana Amanda Bhutani, Nidhi Stone, Laura Cruz-Almeida, Yenisel Jurisica, Igor Boer, Cindy G. Ramos, Yolande F.M. Rice, Sarah J. Kapoor, Mohit Biosciences Institute Newcastle University Newcastle upon Tyne United Kingdom Division of Orthopedics Osteoarthritis Research Program Schroeder Arthritis Institute University Health Network and Krembil Research Institute University Health Network Toronto ON Canada Department of Medical Biophysics and Computer Science University of Toronto Toronto ON Canada Department of Biomedical Data Sciences Section Molecular Epidemiology Leiden University Medical Center Leiden Netherlands Department of Human Evolutionary Biology Harvard University Cambridge MA United States Bone and Joint Institute and Department of Medicine Schulich School of Medicine and Dentistry Western University London Canada Curriculum in Bioinformatics and Computational Biology University of North Carolina Chapel Hill NC United States Laboratory of Tissue Homeostasis and Disease Skeletal Biology and Engineering Research Centre Department of Development and Regeneration KU Leuven Leuven Belgium Division of Rheumatology University Hospitals Leuven Leuven Belgium Rheumatology Department of Musculoskeletal Medicine Lausanne University Hospital and University of Lausanne (CHUV-UNIL) Lausanne Switzerland Bone and Joint Center Henry Ford Health + Michigan State University Health Sciences Detroit MI United States Department of Orthopaedic Surgery Stanford School of Medicine Stanford CA United States Department of Anesthesiology School of Medicine University of Minnesota Minneapolis MN United States Pain Research and Intervention Center of Excellence (PRICE) at the University of Florida Gainesville FL United States Department of Internal Medicine Genomics Medicine Center Erasmus MC University Medical Center Rotterdam Netherlands Department of Laboratory Medicine and Pathobiology University of Toronto Toronto ON Canada Department of Surgery University of Toronto Toronto ON Canada
Objective: Osteoarthritis (OA) is a chronic, degenerative disease of the articular joints. The disease presents an enormous clinical and economic burden globally, due in part to the lack of disease modifying therapies...
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14 Quantitative modeling of transcription factor binding specificities using DNA shape
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Journal of Biomolecular Structure and Dynamics 2015年 第SUPP 1期33卷 8-9页
作者: Tianyin Zhou[a] Ning Shen[b] Lin Yang[a] Namiko Abe[c] John Horton[b] Richard S. Mann[c] Harmen J. Bussemaker[d] Raluca Gordan[b] Remo Rohs[a][*] [a] Molecular and Computational Biology Program University of Southern California Los Angeles CA 90089 USA[b] Center for Genomic and Computational Biology Duke University Durham NC 27708 USA[c] Department of Biochemistry and Molecular Biophysics Columbia University Medical Center New York NY 10032 USA[d] Department of Biological Sciences Columbia University New York NY 10027 USA
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Convolutional neural networks for automated annotation of cellular cryo-electron tomograms
arXiv
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arXiv 2017年
作者: Chen, Muyuan Dai, Wei Sun, Stella Y. Jonasch, Darius He, Cynthia Y. Schmid, Michael F. Chiu, Wah Ludtke, Steven J. Graduate Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine HoustonTX77030 United States Verna Marrs and McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine HoustonTX77030 United States Department of Biological Science Centre for BioImaging Sciences National University of Singapore 14 Science Drive 4 Singapore117543 Singapore
Cellular Electron Cryotomography (CryoET) offers the ability to look inside cells and observe macromolecules frozen in action. A primary challenge for this technique is identifying and extracting the molecular compone... 详细信息
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A Bayesian model for SNP discovery based on next-generation sequencing data
A Bayesian model for SNP discovery based on next-generation ...
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IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)
作者: Yanxun Xu Xiaofeng Zheng Yuan Yuan Marcos R Estecio Jean-Pierre Issa Yuan Ji Shoudan Liang Department of Statistics Rice University Houston TX USA Department of Bioinformatics and Computational Biology University of Texas M.D. Anderson Cancer Center Houston TX USA Graduate Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine Houston TX USA Department of Biochemistry and Molecular Biology University of Texas M.D. Anderson Cancer Center Houston TX USA Fels Institute for Cancer Research and Molecular Biology Temple University Philadelphia PA USA CCRI NorthShore University HealthSystem Chicago IL USA
A single-nucleotide polymorphism (SNP) is a single base change in the DNA sequence and is the most common polymorphism. Since some SNPs have a major influence on disease susceptibility, detecting SNPs plays an importa... 详细信息
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Autofix for backward-fit sidechains: Using MolProbity and real-space refinement to put misfits in their place
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Journal of structural and Functional Genomics 2009年 第1期10卷 83-93页
作者: Headd, Jeffrey J. Immormino, Robert M. Keedy, Daniel A. Emsley, Paul Richardson, David C. Richardson, Jane S. Department of Biochemistry Duke University Medical Center 211 Nanaline Duke Building Durham NC 27710 United States Computational Biology and Bioinformatics Program Duke University Durham NC 27708 United States Department of Immunology University of Washington School of Medicine Seattle WA 98195 United States Laboratory of Molecular Biophysics Department of Biochemistry University of Oxford Oxford Oxfordshire 0X1 3QU United Kingdom
Misfit sidechains in protein crystal structures are a stumbling block in using those structures to direct further scientific inference. Problems due to surface disorder and poor electron density are very difficult to ... 详细信息
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Advances to tackle backbone flexibility in protein docking
arXiv
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arXiv 2020年
作者: Harmalkar, Ameya Gray, Jeffrey J. Department of Chemical and Biomolecular Engineering Johns Hopkins University BaltimoreMD United States Program in Molecular Biophysics Institute for Nanobiotechnology Center for Computational Biology Johns Hopkins University BaltimoreMD United States
computational docking methods can provide structural models of protein-protein complexes, but protein backbone flexibility upon association often thwarts accurate predictions. In recent blind challenges, medium or hig... 详细信息
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