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检索条件"机构=Program in Structural and Computational Biology and Molecular Biophysics"
263 条 记 录,以下是81-90 订阅
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NMR solution structure of Thermotoga maritima protein TM1509 reveals a Zn-metalloprotease-like tertiary structure
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Journal of structural and Functional Genomics 2005年 第1期6卷 51-62页
作者: Hervé Du Penhoat, Catherine Li, Zhaohui Atreya, Hanudatta S. Kim, Seho Yee, Adelinda Xiao, Rong Murray, Diana Arrowsmith, Cheryl H. Szyperski, Thomas Department of Chemistry University of Buffalo State University of New York Buffalo NY 14260 United States Department of Microbiology and Immunology Institute for Computational Biomedicine B-314 Weill Medical College of Cornell University New York NY 10021 1300 York Avenue United States Division of Molecular and Structural Biology Ontario Cancer Institute Toronto Ont. Canada Department of Medical Biophysics University of Toronto Toronto Ont. Canada Center for Advanced Biotechnology and Medicine Department of Molecular Biology and Biochemistry Rutgers University Piscataway NJ 08854 679 Hoes Lane United States Northeast Structural Genomics Consortium Rutgers University Piscataway NJ 08854 610 Taylor Road United States Chemistry Department Rutgers University Piscataway NJ 08854 610 Taylor Road United States
The 150-residue protein TM1509 is encoded in gene YF09_THEMA of Thermotoga maritima. TM1509 has so far no functional annotation and belongs to protein family UPF0054 (PFAM accession number: PF02130) which contains at ... 详细信息
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BPS2025 - Development and benchmarking of the open force field initiative self-consistent force field for proteins and small molecules
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Biophysical Journal 2025年 第3期124卷 483a-484a页
作者: Chapin E. Cavender Pavan K. Behara Anika J. Friedman Joshua T. Horton Alexandra R. McIsaac Louis G. Smith Matthew W. Thompson Jeffrey Wagner Lily Wang Brent R. Westbrook John D. Chodera Daniel Cole David L. Mobley Michael R. Shirts Michael K. Gilson Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San Diego La Jolla CA USA Center for Neurotherapeutics University of California Irvine Irvine CA USA Department of Chemical and Biological Engineering University of Colorado Boulder Boulder CO USA School of Natural and Environmental Sciences Newcastle University Newcastle upon Tyne United Kingdom Open Force Field Consortium Open Molecular Software Foundation Davis CA USA Department of Biochemistry and Biophysics University of Pennsylvania Philadelphia PA USA Computational & Systems Biology Program Memorial Sloan Kettering Cancer Center New York NY USA Department of Pharmaceutical Sciences and Department of Chemistry University of California Irvine Irvine CA USA
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Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and-C2
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细胞研究(英文版) 2017年 第8期27卷 989-1001页
作者: Meisheng Ma Jun-Jie Liu Yan Li Yuwei Huang Na Ta Yang Chen Hua Fu Ming-Da Ye Yuehe Ding Weijiao Huang Jia Wang Meng-Qiu Dong Li Yu Hong-Wei Wang The State Key Laboratory of Membrane Biology Tsinghua University-Peking University Joint Center for Life Sciences School of Life Sciences Tsinghua University Beijing 100084 China Molecular Biophysics and Integrated Bioimaging Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Ministry of Education Key Laboratory of Protein Sciences Tsinghua-Peking Joint Center for Life Sciences Beijing Advanced Innovation Center for Structural Biology School of Life SciencesTsinghua University Beijing 100084 China The State Key Laboratory of Membrane Biology Tsinghua University-Peking University Joint Center for Life Sciences School of Life Sciences Tsinghua University Beijing 100084 China Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science Tsinghua University Beijing 100084 China MOH Key Laboratory of Systems Biology of Pathogens Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100730 China National Institute of Biological Sciences Beijing 102206 China
Phosphatidylinositol 3-phosphate (PI3P) plays essential roles in vesicular trafficking,organelle biogenesis and *** class Ⅲ phosphatidylinositol 3-kinase (PI3KC3) complexes have been identified in mammals,the ATG14L ... 详细信息
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Microano-fabrication technologies for cell biology
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Medical & Biological Engineering & Computing 2010年 第10期48卷 1023-1032页
作者: Qian, Tongcheng Wang, Yingxiao Department of Bioengineering and the Beckman Institute for Advanced Science and Technology University of Illinois at Urbana–Champaign Urbana USA Department of Biomedical Engineering Peking University Beijing People’s Republic of China Department of Integrative and Molecular Physiology Center for Biophysics and Computational Biology Institute for Genomic Biology Neuroscience Program University of Illinois at Urbana–Champaign Urbana USA
Micro/nano-fabrication techniques, such as soft lithography and electrospinning, have been well-developed and widely applied in many research fields in the past decade. Due to the low costs and simple procedures, thes...
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Distinct mechanisms of FAK mechanoactivation by different extracellular matrix proteins
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医用生物力学 2013年 第S1期28卷 69-71页
作者: Jihye Seong Arash Tajik Jie Sun Jun-Lin Guan Martin J.Humphries Susan E.Craig Asha Shekaran Andrs J.García Ning Wang Yingxiao Wang Neuroscience Program University of Illinois Department of Mechanical Science and Engineering University of Illinois Department of Bioengineering & Beckman Institute for Advanced Science and Technology University of Illinois Division of Molecular Medicine and Genetics Departments of Internal Medicine and Cell & DevelopmentalBiologyUniversity of Michigan Medical School Wellcome Trust Centre for Cell-Matrix Research Faculty of Life SciencesUniversity of Manchester Woodruff School of Mechanical Engineering and Petit Institute for Bioengineering and Bioscience Georgia Institute of Technology Department of Biomedical Engineering School of Life Science and TechnologyHuazhong University of Science and Technology Department of Integrative and Molecular Physiology Center for Biophysics and Computational BiologyInstitute for Genomic BiologyUniversity of Illinois Department of Bioengineering University of California
Introduction Cells can sense and respond to the mechanical microenvironment by converting forces into biochemical signals inside the cells,***[1-3].Focal adhesions are the major sites of interaction between a cell and... 详细信息
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ϕ-Value Analysis for Ultrafast Folding Proteins by NMR Relaxation Dispersion
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Journal of the American Chemical Society 2009年 第2期132卷 450-451页
作者: Jae-Hyun Cho Nichole O’Connell Daniel P. Raleigh Arthur G. Palmer, III Department of Biochemistry and Molecular Biophysics Columbia University 630 West 168th Street New York New York 10032 and Department of Chemistry and Graduate Program in Biochemistry and Structural Biology State University of New York at Stony Brook Stony Brook New York 11794
Proteins that fold rapidly, on the (sub-) microsecond time scale, offer the prospect of direct comparison between experimental data and molecular dynamics simulations. However, experimental studies for such proteins f... 详细信息
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Identifying interaction sites in "Recalcitrant" proteins: Predicted protein and RNA binding sites in REV proteins of HIV-1 and EIAV agree with experimental data
Identifying interaction sites in "Recalcitrant" proteins: Pr...
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11th Pacific Symposium on Biocomputing 2006, PSB 2006
作者: Terribllini, Michael Lee, Jae-Hyung Yan, Changhui Jernigan, Robert L. Carpenter, Susan Honavar, Vasant Dobbs, Drena Bioinformatics and Computational Biology Graduate Program LH. Baker Center for Bioinformatics and Biological Statistics Iowa State University Ames IA 50010 United States Department of Computer Science Iowa State University Ames IA 50010 United States Department of Biochemistry Biophysics and Molecular Biology Iowa State University Ames IA 50010 United States Department of Genetics Development and Cell Biology Iowa State University Ames IA 50010 United States Artificial Intelligence Research Laboratory Center for Computational Intelligence Learning and Discovery Iowa State University Ames IA 50010 United States Department of Veterinary Microbiology and Pathology Washington State University Pullman WA. 99164 United States
Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation or gene expression, protein synthesis, and replication and assembly of many vi... 详细信息
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Causes of evolutionary divergence in prostate cancer
arXiv
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arXiv 2025年
作者: Esentürk, Emre Sahli, Atef Haberland, Valeriia Ziuboniewicz, Aleksandra Wirth, Christopher Bova, G. Steven Bristow, Robert G. Brook, Mark N. Brors, Benedikt Butler, Adam Cancel-Tassin, Géraldine Cheng, Kevin C.L. Cooper, Colin S. Corcoran, Niall M. Cussenot, Olivier Eeles, Ros A. Favero, Francesco Gerhauser, Clarissa Gihawi, Abraham Girma, Etsehiwot G. Gnanapragasam, Vincent J. Gruber, Andreas J. Hamid, Anis Hayes, Vanessa M. He, Housheng Hansen Hovens, Christopher M. Imada, Eddie Luidy Jakobsdottir, G. Maria Jung, Chol-Hee Khani, Francesca Kote-Jarai, Zsofia Lamy, Philippe Leeman, Gregory Loda, Massimo Lutsik, Pavlo Marchionni, Luigi Molania, Ramyar Papenfuss, Anthony T. Pellegrina, Diogo Pope, Bernard Queiroz, Lucio R. Rausch, Tobias Reimand, Jüri Robinson, Brian Schlomm, Thorsten Sørensen, Karina D. Uhrig, Sebastian Weischenfeldt, Joachim Xu, Yaobo Yamaguchi, Takafumi N. Zanettini, Claudio Lynch, Andy G. Wedge, David C. Brewer, Daniel S. Woodcock, Dan J. Nuffield Department of Medicine University of Oxford United Kingdom Manchester Cancer Research Centre The University of Manchester United Kingdom Norwich Medical School University of East Anglia United Kingdom Nuffield Department of Surgical Sciences University of Oxford United Kingdom Prostate Cancer Research Center Faculty of Medicine and Health Technology Tampere University Finland Manchester Cancer Research Centre Cancer Research UK Manchester Institute The University of Manchester United Kingdom Christie NHS Foundation Trust United Kingdom Div Cancer Sciences Faculty of Biology Medicine & Health University of Manchester United Kingdom The Institute of Cancer Research United Kingdom Germany Germany Medical Faculty Heidelberg Faculty of Biosciences Heidelberg University Germany Wellcome Sanger Institute United Kingdom France Sorbonne Université GRC n°5 Predictive Onco-Urology APHP Tenon Hospital France Computational Biology Program Ontario Institute for Cancer Research Canada Department of Medical Biophysics University of Toronto Canada Department of Urology Royal Melbourne Hospital Australia Department of Surgery The University of Melbourne Australia Department of Urology Western Health Australia The Royal Marsden NHS Foundation Trust London United Kingdom University of Copenhagen Denmark Finsen Laboratory Copenhagen University Hospital - Rigshospitalet Denmark Germany Cambridge Biomedical Campus Addenbrooke's Hospital Site S Wards Building United Kingdom University of Konstanz Germany School of Medical Sciences University of Sydney Faculty of Medicine & Health Australia School of Health Systems & Public Health University of Pretoria South Africa Manchester Cancer Research Centre University of Manchester United Kingdom Princess Margaret Cancer Centre University Health Network Department of Medical Biophysics University of Toronto Canada Department of Surgery The Collaborative Centre for Genomic Cancer Medicine The University of Melbourne
Cancer progression involves the sequential accumulation of genetic alterations that cumulatively shape the tumour phenotype. In prostate cancer, tumours can follow divergent evolutionary trajectories that lead to dist... 详细信息
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Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals
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Cell 2025年 第10期188卷 2794-2809.e21页
作者: Mi, Xuelong Chen, Alex Bo-Yuan Duarte, Daniela Carey, Erin Taylor, Charlotte R. Braaker, Philipp N. Bright, Mark Almeida, Rafael G. Lim, Jing-Xuan Ruetten, Virginia M.S. Wang, Yizhi Wang, Mengfan Zhang, Weizhan Zheng, Wei Reitman, Michael E. Huang, Yongkang Wang, Xiaoyu Li, Lei Deng, HanFei Shi, Song-Hai Poskanzer, Kira E. Lyons, David A. Nimmerjahn, Axel Ahrens, Misha B. Yu, Guoqiang Bradley Department of Electrical and Computer Engineering Virginia Polytechnic Institute and State University Arlington 22203 VA United States Janelia Research Campus Howard Hughes Medical Institute Ashburn 20147 VA United States Department of Molecular and Cellular Biology Harvard University Cambridge 02138 MA United States Graduate Program in Neuroscience Harvard Medical School Boston 02115 MA United States Waitt Advanced Biophotonics Center The Salk Institute for Biological Studies La Jolla 92037 CA United States Department of Biochemistry & Biophysics University of California San Francisco San Francisco CA United States Neuroscience Graduate Program University of California San Francisco San Francisco CA United States Centre for Discovery Brain Sciences University of Edinburgh Edinburgh BioQuarter Edinburgh EH16 4SB United Kingdom Gatsby Computational Neuroscience Unit UCL London W1T 4JG United Kingdom Kavli Institute for Fundamental Neuroscience San Francisco CA United States Department of Automation Tsinghua University Beijing 100084 China IDG/McGovern Institute for Brain Research Tsinghua University Beijing 100084 China New Cornerstone Science Laboratory Tsinghua-Peking Center for Life Sciences Beijing Frontier Research Center for Biological Structure School of Life Sciences Tsinghua University Beijing 100084 China State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain Science Fudan University Shanghai 200032 China Beijing National Research Center for Information Science and Technology Beijing 100084 China
Optical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new or improved biosensors and microscopy technology. This creates maj... 详细信息
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Origin of Overstretching Transitions in Single-Stranded Nucleic Acids
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Physical Review Letters 2013年 第18期111卷 188302-188302页
作者: Zackary N. Scholl Mahir Rabbi David Lee Laura Manson Hanna S-Gracz Piotr E. Marszalek Program in Computational Biology and Bioinformatics Duke University Durham North Carolina 27708 USA Department of Mechanical Engineering and Materials Science Center for Biologically Inspired Materials and Material Systems Duke University Durham North Carolina 27708 USA Department of Molecular and Structural Biochemistry North Carolina State University Raleigh North Carolina 27708 USA
We combined single-molecule force spectroscopy with nuclear magnetic resonance measurements and molecular mechanics simulations to examine overstretching transitions in single-stranded nucleic acids. In single-strande... 详细信息
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