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检索条件"机构=Program in Structural and Computational Biology and Molecular Biophysics"
256 条 记 录,以下是81-90 订阅
排序:
Identifying interaction sites in "Recalcitrant" proteins: Predicted protein and RNA binding sites in REV proteins of HIV-1 and EIAV agree with experimental data
Identifying interaction sites in "Recalcitrant" proteins: Pr...
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11th Pacific Symposium on Biocomputing 2006, PSB 2006
作者: Terribllini, Michael Lee, Jae-Hyung Yan, Changhui Jernigan, Robert L. Carpenter, Susan Honavar, Vasant Dobbs, Drena Bioinformatics and Computational Biology Graduate Program LH. Baker Center for Bioinformatics and Biological Statistics Iowa State University Ames IA 50010 United States Department of Computer Science Iowa State University Ames IA 50010 United States Department of Biochemistry Biophysics and Molecular Biology Iowa State University Ames IA 50010 United States Department of Genetics Development and Cell Biology Iowa State University Ames IA 50010 United States Artificial Intelligence Research Laboratory Center for Computational Intelligence Learning and Discovery Iowa State University Ames IA 50010 United States Department of Veterinary Microbiology and Pathology Washington State University Pullman WA. 99164 United States
Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation or gene expression, protein synthesis, and replication and assembly of many vi... 详细信息
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Causes of evolutionary divergence in prostate cancer
arXiv
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arXiv 2025年
作者: Esentürk, Emre Sahli, Atef Haberland, Valeriia Ziuboniewicz, Aleksandra Wirth, Christopher Bova, G. Steven Bristow, Robert G. Brook, Mark N. Brors, Benedikt Butler, Adam Cancel-Tassin, Géraldine Cheng, Kevin C.L. Cooper, Colin S. Corcoran, Niall M. Cussenot, Olivier Eeles, Ros A. Favero, Francesco Gerhauser, Clarissa Gihawi, Abraham Girma, Etsehiwot G. Gnanapragasam, Vincent J. Gruber, Andreas J. Hamid, Anis Hayes, Vanessa M. He, Housheng Hansen Hovens, Christopher M. Imada, Eddie Luidy Jakobsdottir, G. Maria Jung, Chol-Hee Khani, Francesca Kote-Jarai, Zsofia Lamy, Philippe Leeman, Gregory Loda, Massimo Lutsik, Pavlo Marchionni, Luigi Molania, Ramyar Papenfuss, Anthony T. Pellegrina, Diogo Pope, Bernard Queiroz, Lucio R. Rausch, Tobias Reimand, Jüri Robinson, Brian Schlomm, Thorsten Sørensen, Karina D. Uhrig, Sebastian Weischenfeldt, Joachim Xu, Yaobo Yamaguchi, Takafumi N. Zanettini, Claudio Lynch, Andy G. Wedge, David C. Brewer, Daniel S. Woodcock, Dan J. Nuffield Department of Medicine University of Oxford United Kingdom Manchester Cancer Research Centre The University of Manchester United Kingdom Norwich Medical School University of East Anglia United Kingdom Nuffield Department of Surgical Sciences University of Oxford United Kingdom Prostate Cancer Research Center Faculty of Medicine and Health Technology Tampere University Finland Manchester Cancer Research Centre Cancer Research UK Manchester Institute The University of Manchester United Kingdom Christie NHS Foundation Trust United Kingdom Div Cancer Sciences Faculty of Biology Medicine & Health University of Manchester United Kingdom The Institute of Cancer Research United Kingdom Germany Germany Medical Faculty Heidelberg Faculty of Biosciences Heidelberg University Germany Wellcome Sanger Institute United Kingdom France Sorbonne Université GRC n°5 Predictive Onco-Urology APHP Tenon Hospital France Computational Biology Program Ontario Institute for Cancer Research Canada Department of Medical Biophysics University of Toronto Canada Department of Urology Royal Melbourne Hospital Australia Department of Surgery The University of Melbourne Australia Department of Urology Western Health Australia The Royal Marsden NHS Foundation Trust London United Kingdom University of Copenhagen Denmark Finsen Laboratory Copenhagen University Hospital - Rigshospitalet Denmark Germany Cambridge Biomedical Campus Addenbrooke's Hospital Site S Wards Building United Kingdom University of Konstanz Germany School of Medical Sciences University of Sydney Faculty of Medicine & Health Australia School of Health Systems & Public Health University of Pretoria South Africa Manchester Cancer Research Centre University of Manchester United Kingdom Princess Margaret Cancer Centre University Health Network Department of Medical Biophysics University of Toronto Canada Department of Surgery The Collaborative Centre for Genomic Cancer Medicine The University of Melbourne
Cancer progression involves the sequential accumulation of genetic alterations that cumulatively shape the tumour phenotype. In prostate cancer, tumours can follow divergent evolutionary trajectories that lead to dist... 详细信息
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Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals
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Cell 2025年 第10期188卷 2794-2809.e21页
作者: Mi, Xuelong Chen, Alex Bo-Yuan Duarte, Daniela Carey, Erin Taylor, Charlotte R. Braaker, Philipp N. Bright, Mark Almeida, Rafael G. Lim, Jing-Xuan Ruetten, Virginia M.S. Wang, Yizhi Wang, Mengfan Zhang, Weizhan Zheng, Wei Reitman, Michael E. Huang, Yongkang Wang, Xiaoyu Li, Lei Deng, HanFei Shi, Song-Hai Poskanzer, Kira E. Lyons, David A. Nimmerjahn, Axel Ahrens, Misha B. Yu, Guoqiang Bradley Department of Electrical and Computer Engineering Virginia Polytechnic Institute and State University Arlington 22203 VA United States Janelia Research Campus Howard Hughes Medical Institute Ashburn 20147 VA United States Department of Molecular and Cellular Biology Harvard University Cambridge 02138 MA United States Graduate Program in Neuroscience Harvard Medical School Boston 02115 MA United States Waitt Advanced Biophotonics Center The Salk Institute for Biological Studies La Jolla 92037 CA United States Department of Biochemistry & Biophysics University of California San Francisco San Francisco CA United States Neuroscience Graduate Program University of California San Francisco San Francisco CA United States Centre for Discovery Brain Sciences University of Edinburgh Edinburgh BioQuarter Edinburgh EH16 4SB United Kingdom Gatsby Computational Neuroscience Unit UCL London W1T 4JG United Kingdom Kavli Institute for Fundamental Neuroscience San Francisco CA United States Department of Automation Tsinghua University Beijing 100084 China IDG/McGovern Institute for Brain Research Tsinghua University Beijing 100084 China New Cornerstone Science Laboratory Tsinghua-Peking Center for Life Sciences Beijing Frontier Research Center for Biological Structure School of Life Sciences Tsinghua University Beijing 100084 China State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain Science Fudan University Shanghai 200032 China Beijing National Research Center for Information Science and Technology Beijing 100084 China
Optical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new or improved biosensors and microscopy technology. This creates maj... 详细信息
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Origin of Overstretching Transitions in Single-Stranded Nucleic Acids
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Physical Review Letters 2013年 第18期111卷 188302-188302页
作者: Zackary N. Scholl Mahir Rabbi David Lee Laura Manson Hanna S-Gracz Piotr E. Marszalek Program in Computational Biology and Bioinformatics Duke University Durham North Carolina 27708 USA Department of Mechanical Engineering and Materials Science Center for Biologically Inspired Materials and Material Systems Duke University Durham North Carolina 27708 USA Department of Molecular and Structural Biochemistry North Carolina State University Raleigh North Carolina 27708 USA
We combined single-molecule force spectroscopy with nuclear magnetic resonance measurements and molecular mechanics simulations to examine overstretching transitions in single-stranded nucleic acids. In single-strande... 详细信息
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Erratum to: An approach to compare genome tiling microarray and MPSS sequencing data for transcript mapping
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BMC Research Notes 2009年 第1期2卷 1-2页
作者: Rajkumar Sasidharan Ashish Agarwal Joel Rozowsky Mark Gerstein Molecular Biophysics and Biochemistry Department Yale University New Haven CT 06520 USA Department of Plant Biology Carnegie Institution for Science Stanford California 94305 USA Interdepartmental Program in Computational Biology and Bioinformatics Yale University New Haven CT 06520 USA Department of Computer Science Yale University New Haven CT 06520 USA
We are correcting the abstract of our published article ([1]). The sentence that starts "We observe that 4.5% of MPSS tags...." was not scientifically complete in the original abstract, having only two of th...
来源: 评论
structural genomics is the largest contributor of novel structural leverage
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Journal of structural and Functional Genomics 2009年 第2期10卷 181-191页
作者: Nair, Rajesh Liu, Jinfeng Soong, Ta-Tsen Acton, Thomas B. Everett, John K. Kouranov, Andrei Fiser, Andras Godzik, Adam Jaroszewski, Lukasz Orengo, Christine Montelione, Gaetano T. Rost, Burkhard Department of Biochemistry and Molecular Biophysics Columbia University New York NY 10032 630 West 168th St. United States Northeast Structural Genomics Consortium (NESG) Columbia University Center for Computational Biology and Bioinformatics (C2B2) Columbia University New York NY 10032 1130 St. Nicholas Ave. United States Department of Biomedical Informatics Columbia University New York NY 10032 630 West 168th St. United States Center for Advanced Biotechnology Department of Molecular Biology and Biochemistry Rutgers University Piscataway NJ 679 Hoes Lane United States Protein Structure Initiative Knowledge Base and RCSB PDB Department of Chemistry and Chemical Biology Rutgers University Piscataway NJ 08854-8087 610 Taylor Rd. United States New York SGX Research Center for Structural Genomics (NYSGXRC) Department of Systems and Computational Biology Albert Einstein College of Medicine New York NY United States Joint Center for Structural Genomics (JCSG) Burnham Research Institute San Diego CA United States Midwest Center of Structural Genomics (MCSG) Department of Structural Biology University College of London (UCL) London WC1E 6BT United Kingdom Department of Biochemistry Robert Wood Johnson Medical School University of Medicine and Dentistry of New Jersey Piscataway NJ 08854 United States New York Consortium on Membrane Protein Structure (NYCOMPS) Columbia University New York NY 10032 1130 St. Nicholas Ave. United States
The Protein structural Initiative (PSI) at the US National Institutes of Health (NIH) is funding four large-scale centers for structural genomics (SG). These centers systematically target many large families without s... 详细信息
来源: 评论
structural genomics target selection for the New York consortium on membrane protein structure
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Journal of structural and Functional Genomics 2009年 第4期10卷 255-268页
作者: Punta, Marco Love, James Handelman, Samuel Hunt, John F. Shapiro, Lawrence Hendrickson, Wayne A. Rost, Burkhard Department of Biochemistry and Molecular Biophysics Columbia University New York NY 10032 630 West 168th Street United States Columbia University Center for Computational Biology and Bioinformatics (C2B2) New York NY 10032 1130 St. Nicholas Ave. United States New York Consortium on Membrane Protein Structure New York Structural Biology Center New York NY 10027 89 Convent Avenue United States Department of Biological Sciences Columbia University New York NY 10032 United States Howard Hughes Medical Institute Columbia University New York NY 10032 United States Northeast Structural Genomics Consortium (NESG) New York NY 10032 1130 St. Nicholas Ave. United States
The New York Consortium on Membrane Protein Structure (NYCOMPS), a part of the Protein Structure Initiative (PSI) in the USA, has as its mission to establish a high-throughput pipeline for determination of novel integ... 详细信息
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Late Residual γ-H2AX Foci In Murine Skin are Dose Responsive and Predict Radiosensitivity In Vivo. (vol 172, pg 1, 2010)
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RADIATION RESEARCH 2010年 第3期173卷 399-400页
作者: Bhogal, N. Kaspler, P. Jalali, F. Hyrien, O. Chen, R. Hill, R. P. Bristow, R. G. [a]Applied Molecular Oncology and Radiation Medicine Program Ontario Cancer Institute/Princess Margaret Hospital (UHN) Toronto Ontario Canada [b]Department of Biostatistics and Computational Biology University of Rochester Medical Center Rochester New York [c]Departments of Medical Biophysics and Radiation Oncology University of Toronto Toronto Ontario Canada Bhogal N. Kaspler P. Jalali F. Hyrien O. Chen R. Hill R. P. and Bristow R. G. Late Residual γ-H2AX Foci In Murine Skin are Dose Responsive and Predict Radiosensitivity In Vivo.
Accurate biodosimetry is needed to estimate radiation doses received in vivo from accidental or unwarranted radiation exposures. We investigated the use of DNA repair foci (e.g. γ-H2AX) at late times after irradiatio... 详细信息
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Network Analysis as a Grand Unifier in Biomedical Data Science
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Biomedical Data Science 1000年 第1期1卷 153-180页
作者: Patrick McGillivray Declan Clarke William Meyerson Jing Zhang Donghoon Lee Mengting Gu Sushant Kumar Holly Zhou Mark Gerstein 1Department of Molecular Biophysics and Biochemistry Yale University New Haven Connecticut 06520 USA email: mark@*** 2Program in Computational Biology and Bioinformatics Yale University New Haven Connecticut 06520 USA 3Department of Computer Science Yale University New Haven Connecticut 06520 USA
Biomedical data scientists study many types of networks, ranging from those formed by neurons to those created by molecular interactions. People often criticize these networks as uninterpretable diagrams termed hairba... 详细信息
来源: 评论
computational approaches to understanding protein aggregation in neurodegeneration
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Journal of molecular Cell biology 2014年 第2期8卷 104-115页
作者: Rachel L. Redler David Shirvanyants Onur Dagliyan Feng Ding Doo Nam Kim Pradeep Kota Elizabeth A. Proctor Srinivas Ramachandran Arpit Tandon Nikolay V. Dokholyan Department of Biochemistry and Biophysics University of North Carolina at Chapel Hill Chapel Hill NC USA Program in Cellular and Molecular Biophysics University of North Carolina at Chapel Hill Chapel Hill NC USA Curriculum in Bioinformatics and Computational Biology University of North Carolina at Chapel Hill Chapel Hill NC USA Center for Computational and Systems Biology University of NorthCarolina at Chapel Hill chapel Hill NC USA Department of Physics and Astronomy Ctemson University Ctemson SC USA Cellular Growth Mechanisms Section Laboratory of Cell and Developmental Signaling Frederick National Laboratory for Cancer Research Frederick MD USA Division of Basic Sciences Fred Hutchison Cancer Research Center Seatt{e WA USA
The generation of toxic non-native protein conformers has emerged as a unifying thread among disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Atomic-level detail regardi... 详细信息
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