Polyetheretherketone(PEEK)has been an alternative material for titanium in bone defect repair,but its clinical application is limited by its poor *** this study,a porous structural design and activated surface modific...
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Polyetheretherketone(PEEK)has been an alternative material for titanium in bone defect repair,but its clinical application is limited by its poor *** this study,a porous structural design and activated surface modification were used to enhance the osseointegration capacity of PEEK *** PEEK scaffolds were manufactured via fused deposition modeling and a polydopamine(PDA)coating chelated with magnesium ions(Mg^(2+))was utilized on the *** surface modification,the hydrophilicity of PEEK scaffolds was significantly enhanced,and bioactive Mg^(2+)could be *** vitro results showed that the activated surface could promote cell proliferation and adhesion and contribute to osteoblast differentiation and mineralization;the released Mg^(2+)promoted angiogenesis and might contribute to the formation of osteogenic H-type ***,porous PEEK scaffolds were implanted in rabbit femoral condyles for in vivo evaluation of *** results showed that the customized three-dimensional porous structure facilitated vascular ingrowth and bone ingrowth within the PEEK *** PDA coating enhanced the interfacial osseointegration of porous PEEK scaffolds and the released Mg^(2+)accelerated early bone ingrowth by promoting early angiogenesis during the coating degradation *** study provides an efficient solution for enhancing the osseointegration of PEEK materials,which has high potential for translational clinical applications.
Quantum-well resonance is achieved through partial confinement in magnetic tunnel junctions (MTJs), which provides an additional operable degree of freedom to regulate quantum-well levels. Using Al/Fe/MgO/Fe/Al and Ag...
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Quantum-well resonance is achieved through partial confinement in magnetic tunnel junctions (MTJs), which provides an additional operable degree of freedom to regulate quantum-well levels. Using Al/Fe/MgO/Fe/Al and Ag/Al/Fe/MgO/Fe/Al/Ag MTJs as examples, via first-principles calculations, we demonstrate that the partial confinement of Δ1 electrons at the Al/Fe interface, and the full confinement at the Fe/MgO interface combine to produce quantum-well resonances in Fe. The quantum-well levels of Fe can be periodically adjusted by two degrees of freedom: Fe and Al thickness. The oscillation period obtained from conductance G↑↑ of MTJs is 2.13 ML Fe (9 ML Al), close to 2.25 ML Fe (8.33 ML Al) calculated by Fermi wave vector in the bcc-Fe (fcc-Al) band. The combination of long and short periods enables quantum-well levels to be finely adjusted. An ultrahigh optimistic TMR effect of 3.05×105% is achieved. Our results provide a way for designing high-performance spintronics devices.
The inverse Faraday effect is an opto-magnetic phenomenon that describes the ability of circularly polarized light to induce magnetism in solids. The capability of light to control magnetic order in solid state materi...
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Extensive research focuses on 2D MXenes ascribed to their adaptable behavior under external parameters, intrinsic ferroelectric nature through oxidation and their tailored conductive ability resulting in exceptional e...
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High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological *** non-invasive neuromodulation methods offer limited precision at the milimeter ***,we report opticallygenerated foc...
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High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological *** non-invasive neuromodulation methods offer limited precision at the milimeter ***,we report opticallygenerated focused ultrasound(OFUS)for non-invasive brain stimulation with ultrahigh *** is generated by a soft optoacoustic pad(SOAP)fabricated through embedding candle soot nanoparticles in a curved polydimethylsiloxane *** generates a transcranial ultrasound focus at 15 MHz with an ultrahigh lateral resolution of 83μm,which is two orders of magnitude smaller than that of conventional transcranial-focused ultrasound(tFUS).Here,we show effective OFUS neurostimulation in vitro with a single ultrasound *** demonstrate submillimeter transcranial stimulation of the mouse motor cortex in *** acoustic energy of 0.6 mJ/cm?,four orders of magnitude less than that of tFUS,is suffcient for successful OFUS *** offers new capabilities for neurosciencestudies and disease treatments by delivering a focus with ultrahigh precision noninvasively.
During epithelial wound healing, cell morphology near the healed wound and the healing rate vary strongly among different developmental stages even for a single species like Drosophila. We develop deformable particle ...
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During epithelial wound healing, cell morphology near the healed wound and the healing rate vary strongly among different developmental stages even for a single species like Drosophila. We develop deformable particle (DP) model simulations to understand how variations in cell mechanics give rise to distinct wound closure phenotypes in the Drosophila embryonic ectoderm and larval wing disc epithelium. We find that plastic deformation of the cell membrane can generate large changes in cell shape consistent with wound closure in the embryonic ectoderm. Our results show that the embryonic ectoderm is best described by cell membranes with an elasto-plastic response, whereas the larval wing disc is best described by cell membranes with an exclusively elastic response. By varying the mechanical response of cell membranes in DP simulations, we recapitulate the wound closure behavior of both the embryonic ectoderm and the larval wing disc.
Visible light-based human–machine interactive media is capable of transmitting electrical readouts to machines and providing intuitive feedback to users ***,many inorganic mechanoluminescent(ML)materials-based intera...
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Visible light-based human–machine interactive media is capable of transmitting electrical readouts to machines and providing intuitive feedback to users ***,many inorganic mechanoluminescent(ML)materials-based interactive media,typically ZnS-loaded phosphors(ZLPs),have been successfully ***,organic ML materials-based solutions were rarely exploited despite their huge merits of strong structural modification,abundant luminescence property,low cost,easy preparation,and so ***,we propose a novel interactive tactile display(ITD)based on organic ML materials(Cz-A6-dye)and triboelectric nanogenerator,with ultra-brightness(130%enhancement)and ultra-low threshold pressure(57%reduction)as compared to *** proposed ITD achieves the conversion of weak mechanical stimuli into visible light and electrical signals simultaneously,without extra power ***,the relationship between the luminous performance of organic ML materials and mechanical force is quantified,benefiting from the uniform ML layer *** by convolutional neural networks,the high-accuracy recognition(97.1%)for handwriting and identity of users is realized at the same ***,the ITD has great potential for intelligent wearable electronics and classified military applications.
In this paper, we develop a novel approach to achieve ultra-high resolution in organic light-emitting diodes (OLEDs) through a photolithography patterning process. It is important to apply a solvent resistant electron...
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Chemical vapor deposition(CVD)has emerged as a promising approach for the controlled growth of graphene films with appealing scalability,controllability,and ***,the synthesis of high-quality graphene films still suffe...
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Chemical vapor deposition(CVD)has emerged as a promising approach for the controlled growth of graphene films with appealing scalability,controllability,and ***,the synthesis of high-quality graphene films still suffers from low production capacity and high energy consumption in the conventional hot-wall CVD *** contrast,owing to the different heating mode,cold-wall CVD(CW-CVD)system exhibits promising potential for the industrial-scale production,but the quality of as-received graphene remains inferior with limited domain size and high defect ***,we demonstrated an efficient method for the batch synthesis of high-quality graphene films with millimeter-sized domains based on CW-CVD *** reduced defect density and improved properties,the as-received graphene was proven to be promising candidate material for electronics and anti-corrosion *** study provides a new insight into the quality improvement of graphene derived from CW-CVD system,and paves a new avenue for the industrial production of high-quality graphene films for potential commercial applications.
This study presents a simple benchtop synthetic protocol for the fabrication of silver (Ag) nanostructures in aqueous media using environmentally friendly and inexpensive reagents under mild experimental conditions. N...
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