Combinations of drugs have demonstrated potential therapeutic results in controlling the progression of cancer, with a possible decrease in toxicity and unfavorable side efects. Experimental screening is no longer fea...
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Combinations of drugs have demonstrated potential therapeutic results in controlling the progression of cancer, with a possible decrease in toxicity and unfavorable side efects. Experimental screening is no longer feasible due to the vast number of possible medication combinations. As a result, the scientific community is becoming more and more interested in creating computational models that can quickly and precisely identify prospective drug combinations. Our methodology employs therapeutically significant drugs and cell line properties in machine learning techniques. Our suggested stacked machine learning model outperforms all other machine learning models taken into consideration. It employs Random Forest and XGBoost as base learners and Logistic Regression as a meta learner. The results of our research underscore the remarkable efficacy of our approach. Not only does it address the complexities of the task at hand, but it also showcases its potential to enhance predictive accuracy within this domain. The comparative analysis reveals that our model exhibits a noteworthy performance improvement across multiple evaluation metrics. Our findings represent a significant step forward in the quest for improved cancer treatment strategies.
Low-light images often suffer from limited visibility and multiple types of degradation, rendering low-light image enhancement (LIE) a nontrivial task. Some endeavors have been made to enhance low-light images using c...
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Reviewing the empirical and theoretical parameter relationships between various parameters is a good way to understand more about contact binary *** this investigation,two-dimensional(2D)relationships for P–MV(system...
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Reviewing the empirical and theoretical parameter relationships between various parameters is a good way to understand more about contact binary *** this investigation,two-dimensional(2D)relationships for P–MV(system),P–L1,2,M1,2–L1,2,and q–Lratiowere *** sample used is related to 118 contact binary systems with an orbital period shorter than 0.6 days whose absolute parameters were estimated based on the Gaia Data Release 3 *** reviewed previous studies on 2D relationships and updated six parameter ***,Markov chain Monte Carlo and Machine Learning methods were used,and the outcomes were *** selected 22 contact binary systems from eight previous studies for comparison,which had light curve solutions using spectroscopic *** results show that the systems are in good agreement with the results of this study.
The fast-paced growth of artificial intelligence applications provides unparalleled opportunities to improve the efficiency of various *** as the transportation sector faces many obstacles following the implementation...
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The fast-paced growth of artificial intelligence applications provides unparalleled opportunities to improve the efficiency of various *** as the transportation sector faces many obstacles following the implementation and integration of different vehicular and environmental aspects *** congestion is among the major issues in this regard which demands serious attention due to the rapid growth in the number of vehicles on the *** address this overwhelming problem,in this article,a cloudbased intelligent road traffic congestion prediction model is proposed that is empowered with a hybrid Neuro-Fuzzy *** aim of the study is to reduce the delay in the queues,the vehicles experience at different road junctions across the *** proposed model also intended to help the automated traffic control systems by minimizing the congestion particularly in a smart city environment where observational data is obtained from various implanted Internet of Things(IoT)sensors across the *** due preprocessing over the cloud server,the proposed approach makes use of this data by incorporating the neuro-fuzzy ***,it possesses a high level of accuracy by means of intelligent decision making with minimum error *** results reveal the accuracy of the proposed model as 98.72%during the validation phase in contrast to the highest accuracies achieved by state-of-the-art techniques in the literature such as 90.6%,95.84%,97.56%and 98.03%,*** far as the training phase analysis is concerned,the proposed scheme exhibits 99.214% accuracy. The proposed prediction modelis a potential contribution towards smart cities environment.
Immersive Technologies have been conventionally used in almost every research area such as medical field, educational domain, tourism, history and heritage and many more. But it has immensely contributed in the medica...
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In this paper, we address the complex problem of detecting overlapping speech segments, a key challenge in speech processing with applications in speaker diarization, automatic transcription, and multi-speaker recogni...
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Early diagnosis of osteonecrosis of the femoral head (ONFH) can inhibit the progression and improve femoral head preservation. The radiograph difference between early ONFH and healthy ones is not apparent to the naked...
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Video encryption is crucial for ensuring the confidentiality of sensitive video data, especially in finance, healthcare, and government industries. With the increasing use of video conferencing and online video stream...
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Navigating the world with visual impairments presents unique challenges, often limiting independence and safety. This research introduces SafeStride, a novel algorithm designed to empower visually impaired individuals...
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Lung cancer remains a major concern in modern oncology due to its high mortality rates and multifaceted origins,including hereditary factors and various clinical *** stands as the deadliest type of cancer and a signif...
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Lung cancer remains a major concern in modern oncology due to its high mortality rates and multifaceted origins,including hereditary factors and various clinical *** stands as the deadliest type of cancer and a significant cause of cancer-related deaths *** diagnosis enables healthcare providers to administer appropriate treatment measures promptly and accurately,leading to improved prognosis and higher survival *** significant increase in both the incidence and mortality rates of lung cancer,particularly its ranking as the second most prevalent cancer among women worldwide,underscores the need for comprehensive research into efficient screening *** in diagnostic techniques,particularly the use of computed tomography(CT)scans,have revolutionized the identification of lung *** scans are renowned for their ability to provide high-resolution images and are particularly effective in detecting small,calcified areas,crucial for identifying earlystage lung ***,there is growing interest in enhancing computer-aided detection(CAD)*** algorithms assist radiologists by reducing false-positive interpretations and improving the accuracy of early cancer *** study aims to enhance the effectiveness of CAD systems through various ***,the Contrast Limited Adaptive Histogram Equalization(CLAHE)algorithm is employed to preprocess CT scan images,thereby improving their visual *** refinement is achieved by integrating different optimization strategies with the CLAHE *** CutMix data augmentation technique is applied to boost the performance of the proposed model.A comparative analysis is conducted using deep learning architectures such as InceptionV3,ResNet101,Xception,and *** study evaluates the performance of these architectures in image classification tasks,both with and without the implementation of the CLAHE *** empirical findings of the study demonst
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