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检索条件"机构=Protein Structure-Function and Research Laboratory"
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Crystallization scale purification of α7 nicotinic acetylcholine receptor from mammalian cells using a BacMam expression system
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中国药理学报（英文版） 2015年 第8期36卷 1013-1023页
作者： Hao CHENG Chen FAN Si-wei ZHANG Zhong-shan WU Zhi-cheng CUI Karsten MELCHER Cheng-hai ZHANG VARI-SIMM Center Center for Structure and Function of Drug Targets CAS-Key Laboratory of Receptor Research Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China National Center for Protein Science Shanghai State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 201210 China VARI-SIMM Center Center for Structure and Function of Drug Targets CAS-Key Laboratory of Receptor Research Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 China Laboratory of Structural Sciences Van Andel Research Institute Grand Rapids MI 49503 USA
Aim:To report our methods for expression and purification of α7 nicotinic acetylcholine receptor (α7-nAChR), a ligand-gated pentameric ion channel and an important drug target.
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