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13th International Conference on Information Technology in Medicine and Education, ITME 2023

作者： Wang, Jie Li, Zuoyong Xu, Haiping Cheng, Xuesong Teng, Shenghua College of Electronic and Information Engineering Shandong University of Science and Technology Qingdao266590 China Fujian Provincial Key Laboratory of Information Processing and Intelligent Control College of Computer and Control Engineering Minjiang University Fuzhou350121 China Fujian Key Laboratory of Medical Big Data Engineering Fujian Provincial Hospital Fuzhou350001 China College of Mathematics and Data Science Minjiang University Fuzhou350121 China

ISBN: (纸本)9798350319156

Colorectal cancer is a common malignancy. In colonoscopy images, computer-assisted polyp segmentation helps doctors diagnose and treat disorders more precisely. In recent years, some methods based on deep convolutional neural networks have made significant breakthroughs in this task. However, only a few algorithms explicitly consider the effect of light intensity on segmentation performance, which results in algorithms needing to be more robust for complex samples. This paper proposes a neural network combining a simple encoding structure with a reverse attention module. Specifically, the model uses HarDNet68 as the backbone network, adds a camouflage identification module (CIM) to enhance the capture of polyp details on the underlying features, and finally utilizes adaptive feature fusion with the reverse attention module (RAM). The proposed model effectively addresses the challenge of poor segmentation quality in colonoscopy images caused by inconsistent illumination. Extensive experiments on five datasets show that the proposed model performs well in polyp segmentation. © 2023 IEEE.

关键词： Diseases

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KAC-Unet: A Medical Image Segmentation With the Adaptive Group Strategy and Kolmogorov-Arnold Network

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IEEE Transactions on Instrumentation and Measurement 2025年 74卷

作者： Lin, Shiying Hu, Rong Li, Zuoyong Lin, Qinghua Zeng, Kun Wu, Xiang Fujian University of Technology Fujian Provincial Key Laboratory of Big Data Mining and Applications School of Computer Science and Mathematics Fuzhou350118 China Minjiang University Fujian Provincial Key Laboratory of Information Processing and Intelligent Control School of Computer and Big Data Fuzhou350121 China Fuzhou University Affiliated Provincial Hospital Provincial Clinical Medical College Fujian Medical University Department of Urology Fuzhou350001 China

In the field of deep learning-based medical image segmentation, convolutional neural networks (CNNs) extract image features by combining linear convolutional layers with nonlinear activation functions. However, excessive stacking of linear layers in the network limits the model’s ability to capture fine-grained details. In addition, the feature distribution imbalance caused by the traditional fixed grouping strategy (FGS) can affect the deep model’s capacity to perceive the overall structure of the image. To address these challenges, we propose a medical image segmentation framework, called Kolmogorov-Arnold Network with the adaptive group strategy and contextual Transformer based on Unet (KAC-Unet). First, we propose the adaptive group strategy (AGS) to balance the grouping of different input channels, alleviating the performance degradation caused by differences in group information. Then, we propose the Shift Tokenized Kolmogorov-Arnold Network (KAN) Block to capture complex features in medical images through flexible nonlinear transformations and shift operations. Extensive experiments are conducted on three medical image segmentation datasets. The results demonstrate the effectiveness and superiority of our proposed method compared with state-of-the-art algorithms. © 1963-2012 IEEE.

关键词： Convolutional neural networks

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MEFA-Net: A mask enhanced feature aggregation network for polyp segmentation

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Computers in Biology and Medicine 2025年 186卷 109601-109601页

作者： Ke, Xiao Chen, Guanhong Liu, Hao Guo, Wenzhong Fujian Provincial Key Laboratory of Networking Computing and Intelligent Information Processing College of Computer and Data Science Fuzhou University Fuzhou350116 China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou350116 China

Accurate polyp segmentation is crucial for early diagnosis and treatment of colorectal cancer. This is a challenging task for three main reasons: (i) the problem of model overfitting and weak generalization due to the multi-center distribution of data;(ii) the problem of interclass ambiguity caused by motion blur and overexposure to endoscopic light;and (iii) the problem of intraclass inconsistency caused by the variety of morphologies and sizes of the same type of polyps. To address these challenges, we propose a new high-precision polyp segmentation framework, MEFA-Net, which consists of three modules, including the plug-and-play Mask Enhancement Module (MEG), Separable Path Attention Enhancement Module (SPAE), and Dynamic Global Attention Pool Module (DGAP). Specifically, firstly, the MEG module regionally masks the high-energy regions of the environment and polyps through a mask, which guides the model to rely on only a small amount of information to distinguish between polyps and background features, avoiding the model from overfitting the environmental information, and improving the robustness of the model. At the same time, this module can effectively counteract the "dark corner phenomenon" in the dataset and further improve the generalization performance of the model. Next, the SPAE module can effectively alleviate the inter-class fuzzy problem by strengthening the feature expression. Then, the DGAP module solves the intra-class inconsistency problem by extracting the invariance of scale, shape and position. Finally, we propose a new evaluation metric, MultiColoScore, for comprehensively evaluating the segmentation performance of the model on five datasets with different domains. We evaluated the new method quantitatively and qualitatively on five datasets using four metrics. Experimental results show that MEFA-Net significantly improves the accuracy of polyp segmentation and outperforms current state-of-the-art algorithms. Code posted on https://***/

关键词： Endoscopy

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An Unsupervised Malicious Web Request Detection based on Transformer and Contrastive Learning

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IEEE Transactions on Network and Service Management 2025年

作者： He, Shiming Zhang, Ying Liang, Diqing Sharma, Pradip Kumar Changsha University of Science and Technology School of Computer Science and Technology Hunan Provincial Key Laboratory of Intelligent Processing of Big Data on Transportation Changsha410114 China University of Aberdeen Department of Computing Science AberdeenAB24 3UE United Kingdom

The World Wide Web (Web) is a crucial part of the Internet. Web attacks are becoming more and more serious and complex. Malicious Web request detection aims to rapidly and accurately identify abnormal attacks on the network. Deep learning is being applied to malicious Web request detection, resulting in high detection performance. However, most deep learning-based methods are supervised and ignore special characters, which are hard to detect unknown malicious Web requests. The labels of Web request are fewer and Web request data is insufficient. Therefore, we propose an unsupervised malicious Web request detection based on transformer and contrastive learning (UTCDetector). UTCDetector exploits preprocessing and 2-gram word segmentationto preserve special characters, extracts semantic feature by Transformer, and leverages hypersphere loss function and contrastive learning to handle insufficient Web data without abnormal label. Since the public Web request datasets (CSIC 2010, CSIC TORPEDA 2012, and ECML/PKDD 2007) were created before 2012, we collected Web requests from a university Web application server in 2023 to build a private dataset named School 2023. This dataset contains more modern and complex attacks. The experimental results on the four datasets demonstrate that our method achieves a higher F1-score than other existing methods and ablation variants. © 2004-2012 IEEE.

关键词： Contrastive Learning

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Image Matching Algorithm Under Adverse Conditions Based on SIFT

Image Matching Algorithm Under Adverse Conditions Based on S...

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IEEE International Symposium on Information (IT) in Medicine and Education, ITME

作者： Hao Chen Xinrong Cao Zuoyong Li Lihui Lin College of Computer and Big Data Fuzhou University Fuzhou China Fujian Provincial Key Laboratory of Information Processing and Intelligent Control School of Computer and Big Data Minjiang University Fuzhou China Fujian Key Laboratory of Big Data Application and Intellectualization for Tea Industry School of Mathematics and Computer Science Wuyi University Fujian China

ISBN: (数字)9798350356670

ISBN: (纸本)9798350356687

Image matching technology is crucial in computer vision applications. However, the traditional SIFT (Scale-Invariant Feature Transform) algorithm often faces challenges under adverse conditions, such as a high number of mismatched points and few accurately matched points. Additionally, in practical scenarios, environmental factors like lighting changes and image blurring further reduce image similarity. Therefore, this paper proposes an improved SIFT-based image matching algorithm to address these challenges. First, SIFT is used to extract image features, and a bidirectional FLANN (Fast Library for Approximate Nearest Neighbors) matching strategy is employed to initially filter out incorrect features. Then, the RANSAC (Random Sample Consensus) algorithm is used to screen out unreliable matching point pairs. Finally, the matching accuracy is evaluated based on the remaining pure matching point pairs. Experimental results demonstrate that, compared to the traditional SIFT algorithm, this improved algorithm achieves higher matching accuracy and robustness under adverse conditions, exhibiting superior performance.

关键词： Location awareness Matched filters Accuracy Image matching Lighting Transforms Feature extraction Robustness Libraries Information technology

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TF-DTA: A Deep Learning Approach Using Transformer Encoder to Predict Drug-Target Binding Affinity

TF-DTA: A Deep Learning Approach Using Transformer Encoder t...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Wenjun Li Yiqiang Zhou Xiwei Tang Hunan Provincial Key Laboratory of Intelligent Processing of Big Data on Transportation Changsha University of Science and Technology Changsha China School of Computer Science Hunan First Normal University Changsha China

Bioinformatics is a rapidly growing field that involves the application of computational methods to analyze and interpret biological data. One important task in bioinformatics is predicting the drug-target affinity (DTA), which plays a significant role in drug discovery through virtual screening. Effectively predicting the association between drug molecules and target molecules can speed up the drug discovery process. The DTA can be quantitatively measured. This quantifiable affinity is more precise than a simple binary relationship. In this study, we propose a deep learning model for DTA prediction that utilizes the encoder module of the Transformer architecture. Our proposed model utilizes Convolutional Neural Networks (CNNs) and the encoder module of Transformer to characterize protein and drug sequences. The model outperforms some methods such as KronRLS, SimBoost and DeepDTA as evidenced by superior evaluation metrics such as Mean Squared Error (MSE), Concordance Index (CI), and Regression toward the Mean Index $\left( {r_m^2} \right)$. These results demonstrate the effectiveness of the Transformer’s encoder in extracting meaningful representations from sequences, thereby improving the accuracy of DTA prediction. Deep learning models for DTA prediction can accelerate drug discovery by identifying drug candidates with high binding affinity to specific targets. Compared to traditional methods, the use of machine learning technology enables more effective and efficient drug discovery.

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MFCM-DTI model of multimodal feature fusion: prediction of drug-target interaction

MFCM-DTI model of multimodal feature fusion: prediction of d...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Wenjun Li Wanjun Ma Mengyun Yang Xiwei Tang Hunan Provincial Key Laboratory of Intelligent Processing of Big Data on Transportation Changsha University of Science and Technology Changsha China School of Computer Science Hunan First Normal University Changsha China School of Intelligent Manufacturing Hunan First Normal University Changsha China

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

Drug repositioning is a vital area of biomedicine, where confirming interactions between drugs and specific targets is essential for establishing the efficacy of pharmaceutical agents. Traditional in vitro screening methods have limitations, prompting the use of computer simulations as an effective alternative for predicting drug-target interactions (DTI). This approach has gained significant attention in the scientific community. In this study, we introduce MFCM-DTI, a DTI prediction model that employs multimodal features to accurately capture the intricate interactions between drug molecular structures and key amino acids of target proteins. Our results demonstrate that MFCM-DTI outperforms existing models in prediction accuracy and robustness. Furthermore, MFCM-DTI has been successfully used to predict interactions between key SARS-CoV-2 proteins and existing drugs, providing a solid foundation for developing therapeutic agents against SARS-CoV-2 infection. This study underscores the broad applicability and strong predictive capabilities of MFCM-DTI in drug-protein interaction prediction, opening new avenues for research. The predicted drug targets and interaction data offer valuable insights for future experimental validation and clinical trials, potentially driving innovation in the biomedical field.

关键词： Drugs Proteins Technological innovation Accuracy Predictive models Feature extraction Solids Robustness Coronaviruses Diffusion tensor imaging

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EDSep: An Effective Diffusion-Based Method for Speech Source Separation

EDSep: An Effective Diffusion-Based Method for Speech Source...

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2025 IEEE International Conference on Acoustics, Speech, and Signal processing, ICASSP 2025

作者： Dong, Jinwei Wang, Xinsheng Mao, Qirong School of Computer Science and Communication Engineering Jiangsu University China Jiangsu Engineering Research Center of Big Data Ubiquitous Perception and Intelligent Agriculture Applications China Provincial Key Laboratory of Computational Intelligence and New Technologies in Low-Altitude Digital Agriculture Zhenjiang China Audio Speech and Language Processing Group School of Computer Science Northwestern Polytechnical University Xi'an China

ISBN: (纸本)9798350368741

Generative models have attracted considerable attention for speech separation tasks, and among these, diffusion-based methods are being explored. Despite the notable success of diffusion techniques in generation tasks, their adaptation to speech separation has encountered challenges, notably slow convergence and suboptimal separation outcomes. To address these issues and enhance the efficacy of diffusion-based speech separation, we introduce EDSep, a novel single-channel method grounded in score matching via stochastic differential equation (SDE). This method enhances generative modeling for speech source separation by optimizing training and sampling efficiency. Specifically, a novel denoiser function is proposed to approximate data distributions, which obtains ideal denoiser outputs. Additionally, a stochastic sampler is carefully designed to resolve the reverse SDE during the sampling process, gradually separating speech from mixtures. Extensive experiments on databases such as WSJ0-2mix, LRS2-2mix, and VoxCeleb2-2mix demonstrate our proposed method's superior performance over existing diffusion and discriminative models, validating its efficacy. © 2025 IEEE.

关键词： diffusion score matching speech separation stochastic differential equation

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big-Moe: Bypassing Isolated Gating For Generalized Multimodal Face Anti-Spoofing

Big-Moe: Bypassing Isolated Gating For Generalized Multimoda...

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International Conference on Acoustics, Speech, and Signal processing (ICASSP)

作者： Yingjie Ma Zitong Yu Xun Lin Weicheng Xie Linlin Shen College of Computer Science and Software Engineering Shenzhen University Great Bay University National Engineering Laboratory for Big Data System Computing Technology Shenzhen University Guangdong Provincial Key Laboratory of Intelligent Information Processing

ISBN: (数字)9798350368741

ISBN: (纸本)9798350368758

In the domain of facial recognition security, multimodal Face Anti-Spoofing (FAS) is essential for countering presentation attacks. However, existing technologies encounter challenges due to modality biases and imbalances, as well as domain shifts. Our research introduces a Mixture of Experts (MoE) model to address these issues effectively. We identified three limitations in traditional MoE approaches to multimodal FAS: (1) Coarse-grained experts’ inability to capture nuanced spoofing indicators; (2) Gated networks’ susceptibility to input noise affecting decision-making; (3) MoE’s sensitivity to prompt tokens leading to overfitting with conventional learning methods. To mitigate these, we propose the Bypass Isolated Gating MoE (big-MoE) framework, featuring: (1) Fine-grained experts for enhanced detection of subtle spoofing cues; (2) An isolation gating mechanism to counteract input noise; (3) A novel differential convolutional prompt bypass enriching the gating network with critical local features, thereby improving perceptual capabilities. Extensive experiments on four benchmark datasets demonstrate significant generalization performance improvement in multimodal FAS task. The code is released at https://***/murInJ/big-MoE.

关键词： Convolutional codes Sensitivity Convolution Face recognition Noise Logic gates Feature extraction Security Speech processing Overfitting

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Learning with Open-world Noisy data via Class-independent Margin in Dual Representation Space

arXiv

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arXiv 2025年

作者： Pan, Linchao Gao, Can Zhou, Jie Wang, Jinbao College of Computer Science and Software Engineering Shenzhen University China Guangdong Provincial Key Laboratory of Intelligent Information Processing China National Engineering Laboratory for Big Data System Computing Technology Shenzhen University China

Learning with Noisy Labels (LNL) aims to improve the model generalization when facing data with noisy labels, and existing methods generally assume that noisy labels come from known classes, called closed-set noise. However, in real-world scenarios, noisy labels from similar unknown classes, i.e., open-set noise, may occur during the training and inference stage. Such open-world noisy labels may significantly impact the performance of LNL methods. In this study, we propose a novel dual-space joint learning method to robustly handle the open-world noise. To mitigate model overfitting on closed-set and open-set noises, a dual representation space is constructed by two networks. One is a projection network that learns shared representations in the prototype space, while the other is a One-Vs-All (OVA) network that makes predictions using unique semantic representations in the class-independent space. Then, bi-level contrastive learning and consistency regularization are introduced in two spaces to enhance the detection capability for data with unknown classes. To benefit from the memorization effects across different types of samples, class-independent margin criteria are designed for sample identification, which selects clean samples, weights closed-set noise, and filters open-set noise effectively. Extensive experiments demonstrate that our method outperforms the state-of-the-art methods and achieves an average accuracy improvement of 4.55% and an AUROC improvement of 6.17% on CIFAR80N. Copyright © 2025, The Authors. All rights reserved.

关键词： Contrastive Learning

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