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IEEE International Symposium on Electromagnetic Compatibility - EMC Europe

作者： Keisuke Fukumasu Masayuki Nunokawa Umberto Paoletti Kiyoto Matsushima Toshiaki Takami Reliable Electronic Systems Research Department Hitachi Ltd. R&D Group CSU-Production Enginnering Kanagawa Japan Rolling Stock Department Shinkansen Operations Division Central Japan Railway Company Tokyo Japan Technology Research and Development Department Central Japan Railway Company Aichi Japan

In order to reduce malfunctions of on-board equipment due to noise generated by inverters in rolling stock, a method for analyzing magnetic field noise received by on-board equipment is required. To achieve this, it was necessary to identify the main currents among the noise currents flowing near the onboard antenna and to construct a model that takes into account the phase of those currents. In the work reported here, we identified that the imbalance between the left and right rail currents contributes to the magnetic field noise and constructed a vehicle-level analysis model that includes these noise currents. The analysis confirmed that the model can represent the variation of noise fluctuation for each frame structure around the on-board equipment up to 2 MHz.

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Wear Mechanisms in Ti(C,N)-Al2o3 Coated Carbide during Sustainable Machining Cgi

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SSrN 2023年

作者： Lindvall, rebecka diaz, Kevin Monroe Peng, ru Lin Gutnichenko, Oleksandr Sirén, Sebastian Åberg, Lena Magnusson Norgren, Susanne M’Saoubi, rachid Bushlya, Volodymyr Ståhl, Jan-Eric Division of Production and Materials Engineering Department of Mechanical Engineering Sciences LTH Lund University Ole Römers väg 1 Lund221 00 Sweden Division of Engineering Materials Department of Management and Engineering Linköping University Linköping581 83 Sweden Material Technology Processes and Specialists Volvo Group Trucks Operations BE63934 Skövde541 87 Sweden Sandvik Coromant R&D Lerkrogsvägen 13 Stockholm126 80 Sweden R&D Materials and Technology Development Seco Tools AB Björnbacksvägen 10 Fagersta737 82 Sweden

By replacing conventional gray cast iron (GI) with compacted graphite iron (CGI), automotive industry could keep up with stricter regulations on emissions and demands on higher engine performance. CGI has improved properties as to GI but is more difficult to machine. This study evaluates the machining performance at sustainable machining during finish face milling when using minimum quantity lubrication applied vegetable oil with and without graphite nano-additive, resulting in 8% or 17–23% improved tool life respectively as to dry conditions. The major part of the study investigates the wear mechanisms in commercial Ti(C,N)-Al2O3 CVd-coated cemented carbide. The coating degrades by mechanically induced cracking and fractures, oxidation of adhered CGI inside cracks, diffusional dissolution of Ti(C,N) layer, and reaction of Al2O3 layer with MgO inclusions forming a softer (Mg,Fe,Mn)Al2O4 spinel which is easier removed by the superficial plastic deformation due to chip flow. Other oxide inclusions, when deposited on cemented carbide surfaces, prevents adhesion of CGI material and thus reduces the wear rate. CGI adhering to cemented carbide induces diffusional loss of cobalt and carbon that eventually forms (Fex,Co1-x)3C iron carbide at the tool-workpiece interface which can reduce the diffusion rate. Novel findings also relates to the formation of 15 µm deep cracks in the cemented carbide due to inward diffusion of Fe accompanied by its oxidation that speeds up the oxygen ingress and further oxidation of W and Co. However, oxidation was found to provide a positive effect when the adhered CGI completely oxidized to form Fe2SiO4 oxide ceramic Tool Protection Layer which slowed down tool material degradation. © 2023, The Authors. All rights reserved.

关键词： Wear of materials

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New technology for Improving Water Flooding Efficiency by Adjusting Advantage Channels 8th

New Technology for Improving Water Flooding Efficiency by Ad...

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8th International Field Exploration and development Conference, IFEdC 2019

作者： Shao, Li-ming Fang, Ping-liang Wei, Fa-lin dai, Ming-li Li, Wei-tao Research Institute of Petroleum Exploration and Development PetroChina Beijing100083 China CNPC Engineering Technology R&D Company Limited PetroChina Beijing100083 China

ISBN: (纸本)9789811524844

Underground cross-linking profile control and water shutoff and deep fluid flow to chemical agent system are usually composed of main agent, cross-linking agent and additives. The cost of cross-linking agent and additives generally accounts for 30–50% of the total cost of the system. Many inorganic salt ions are widely used as cross-linking agent or additives. In this paper, using Ca2+ and Mg2+ scale forming ion source in CaCl2 water type oilfield high salinity formation water (as water injection) as crosslinking agent, cross-linking of original inorganic microgel is carried out to reduce the cost of steering agent. The formation of nano microscale inorganic microgel with density similar to that of environmental water source can be formed by cross-linking of the steering agent with scale forming ions in formation water. The microgel can be dispersed or suspended in water, and gradually adsorbed on the rock skeleton of the dominant channel such as hole or crack to form a micro gel coating in order to narrow the flow dominant channel and form resistance to flow. The passage of plugging does not die, achieving the purpose of adjusting the dominant channel, expanding the volume and improving the efficiency of water flooding. At the same time, the particle size of the micro gel can prevent it from entering the low permeability matrix to contaminate the oil layer. The diversion agent has the characteristics of rapid dissolution, temperature resistance, salt resistance, environmental protection, long-term effectiveness and no construction risk. Field tests of deep profile control and flooding have been carried out in reservoirs with different temperature and salinity at home and abroad. After profile control diversion in test blocks or well groups, the effect of improving water flooding is good. The average increase of water injection pressure is 2–3 MPa, and the effective rate of increasing oil production and precipitation in oil wells is more than 80%, and the validity p

关键词： Chlorine compounds

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An end-edge-cloud technology architecture for integrated intelligent control of small hydropower - an example from Hunan Province, China 10

An end-edge-cloud technology architecture for integrated int...

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10th International Forum on Electrical Engineering and Automation, IFEEA 2023

作者： Zhou, Zhuomin Liang, Jian Yu, Aiqin Qin, Zhengbin Liu, Haotian Sheng, Yanchao Guo, Wei State Grid Hunan Electric Power Company Limited Hunan Key Laboratory of Energy Internet Supply Demand and Operation Development Planning Department Changsha China State Grid Hunan Electric Power Company Limited Institute of Economic Research Hunan Key Laboratory of Energy Internet Supply Demand and Operation Changsha China State Grid Xiangtan Electric Power Company Limited Institute of Economic Research Changsha China Three Gorges Intelligent Industrial Control Technology Co. Ltd. R&d Department Wuhan China

ISBN: (纸本)9798350309379

The main technical issues for small hydropower currently are aging equipment and insufficient intelligence level, which cannot effectively support the development of new power systems. To solve this problem, this paper proposes an end-edge-cloud technology architecture for intelligent control of small hydropower. Specifically, an intelligent sensing architecture for small hydropower units is proposed, which can fully sense the operating conditions of small hydropower units. An edge computing PLC with IOT functions is proposed, which can effectively integrate the speed regulation, excitation, monitoring and protection algorithms of small hydropower units, and can greatly simplify the complexity of control systems. At the same time, the edge computing PLC transmits the on-site operation data to the cloud platform through high-density compression transmission, and uses big data analysis and processing technology to realize centralized monitoring and remote operation and maintenance of small hydropower stations within the province. Finally, the intelligent sensing, integrated edge control device and cloud platform proposed in this paper are technologically verified at a small hydropower station in Jingshan reservoir, and the results fully demonstrate the effectiveness of this technical architecture. © 2023 IEEE.

关键词： control end-edge-cloud technology architecture IOT-PLC small hydropowert

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A pragmatic mixing model for the evaluation of powder flow properties of multicomponent pharmaceutical blends

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International Journal of Pharmaceutics: X 2025年 9卷

作者： Yanes, daniel Shinebaum, rachael Papakostas, Georgios reynolds, Gavin K. Swainson, Sadie M.E. Oral Product Development Pharmaceutical Technology & Development Operations AstraZeneca Macclesfield SK10 2NA United Kingdom School of Pharmacy University of Nottingham University Park Campus Nottingham NG7 2RD United Kingdom Technical Operations Science & Innovation Pharmaceutical Technology & Development Operations AstraZeneca Macclesfield SK10 2NA United Kingdom Early Product Development and Manufacturing Pharmaceutical Sciences BioPharmaceuticals R&D AstraZeneca Macclesfield SK10 2NA United Kingdom Sustainable Innovation & Transformational Excellence (xSITE) Pharmaceutical Technology & Development Operations AstraZeneca Macclesfield SK10 2NA United Kingdom

Maintaining flowability of pharmaceutical blends is critical for operational efficiency in state-of-the-art continuous direct compression (CdC) manufacturing, with poor flow potentially resulting in API loss, increased experimental work and increased time to market. Consequently, flowability is a crucial consideration in the design of formulations and must be considered throughout the development process when changes are introduced. Traditionally, understanding flow properties has required testing large amounts of material, particularly when evaluating formulation options. This has led to research into developing predictive flow models to reduce experimental burden. Current models with good predictive capacity, such as using granular bond number, require non-routine measurements such as mechanical surface energy. Three mixture designs, each using three pharmaceutical materials, were developed to investigate flow properties and allow the evaluation of a number of mixing models for predicting flowability with minimal experimental input requirements. The resultant models ranged in complexity from simple first order mixture models to more complex third order models with binary and ternary interaction parameters. An analysis of the experimental cost versus prediction accuracy suggested that while the more complex models delivered the most accurate predictions, a first order mass weighted model using inverse FFC was capable of providing good predictions in return for a more manageable experimental burden, with an r² value of 0.68, root mean square error of 2.88 and a mean absolute percentage error of 0.21. This model has the potential to provide valuable insights during early formulation design and development where material is scarce and good flowability is crucial. © 2025 The Authors

关键词： Continuous direct compression design of experiment Pharmaceutical powder flow Powder blends Predictive modelling Shear cell

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SPErA Hydrogen System^(TM)by LOHC-MCH Method for Massive Hydrogen Storage and Transportation

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Journal of Environmental Science and Engineering(A) 2024年第2期13卷 50-60页

作者： Yoshimi Okada Kaji Naohiro Osamu Ikeda Kenichi Imagawa Hironori Kawai Masashi Nagai Yasuhiro Inoue Frontier Business Division Chiyoda Corporation4-6-2 Minatomirai Nishi-kuYokohama 2208765Japan Hydrogen Business Department Chiyoda Corporation4-6-2 Minatomirai Nishi-kuYokohama 2208765Japan R&D Center Chiyoda Corporation3-13 Moriya-cho Kanagawa-kuYokohama 2208765Japan Technology Development Department Chiyoda Corporation4-6-2 Minatomirai Nishi-kuYokohama 2208765Japan

Expanding the hydrogen energy utilization is essential for decarbonization,and the commercialization of hydrogen energy carrier systems that can“store”and“transport”hydrogen in a large scale is *** organic chemical hydride method incorporates hydrogen atoms into the molecular structure of a LOHC(Liquid Organic Hydrogen Carrier)to store and transport hydrogen in a liquid state under normal temperature and pressure,and is a highly safe method with low business *** has been developing the technology since 2002,completed a pilot demonstration in 2014 and named it the SPErA Hydrogen^(TM) System,and successfully completed an international supply chain demonstration that transports hydrogen from Brunei to Japan in a large scale in 2020,moving to the commercialization ***,Chiyoda is conducting feasibility studies with a number of domestic and foreign companies with the aim of commercializing the system as soon as *** this paper,outline,features,development status and our efforts in commercialization of SPErA HydrogenTM System are introduced.

关键词： Hydrogen carrier LOHC Methylcyclohexane MCH toluene

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Novel PdE9 inhibitors, Kr39526 and Kr39582, attenuate cardiac hypertrophy and fibrosis induced by pressure overload

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Journal of Pharmacological Sciences 2025年第4期158卷 353-362页

作者： Jeong Hyun Lee Hyunjin Park Seung Hyeong Lee Su Ah Kim Jun Young Choi Chae Jo Lim Ju-Young Shin Byung Ho Lee Kwang-Seok Oh Data Convergence Drug Research Center Korea Research Institute of Chemical Technology Daejeon South Korea Graduate School of New Drug Discovery and Development Chungnam National University Daejeon South Korea R&D Center Huons co. Ltd. Ansan Gyeonggi-do South Korea Department of Biohealth Regulatory Science Sungkyunkwan University Suwon Gyeonggi-do South Korea School of Pharmacy Sungkyunkwan University Suwon Gyeonggi-do South Korea Department of Medicinal and Pharmaceutical Chemistry University of Science and Technology Daejeon South Korea

The natriuretic peptide and cyclic guanosine monophosphate (cGMP) cascade are promising therapeutic target for heart failure. This study evaluated the pharmacological properties and cardioprotective effects of novel phosphodiesterase 9 (PdE9) inhibitors, Kr39526 and Kr39582, in vitro and in vivo . The potency and selectivity of these compounds were assessed through PdE9 inhibitory activity and subfamily selectivity assays. Functional analyses in cardiomyocytes included calcium mobilization, cellular hypertrophy, and protein expression. The cardioprotective efficacy was investigated using a mouse model of pressure-overload-induced cardiac hypertrophy. Kr39526 and Kr39582 demonstrated potent PdE9A inhibitory activities (IC 50 : 5 ± 2 nM and 0.4 ± 0.1 nM, respectively) with high selectivity. This inhibition led to concentration-dependent calcium influx through maintaining intracellular cGMP levels and significantly suppressed phenylephrine-induced cardiomyocyte hypertrophy. Oral administration (50 mg·kg-1) of these compounds markedly attenuated cardiac hypertrophy and myocardial fibrosis induced by pressure overload. These results suggest that Kr39526 and Kr39582, as potent and selective PdE9A inhibitors, have strong potential for exerting anti-hypertrophic and anti-fibrotic effects in heart failure. These compounds can serve as valuable pharmacological tools to elucidate the roles of PdE9A signaling in heart failure pathophysiology and hold significant promise as potential therapeutic agents.

关键词： Phosphodiesterase 9A Inhibitor Heart failure Cardiac hypertrophy Transverse aortic constriction

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Characteristics of GaInAsP/SOI Hybrid Semiconductor Optical Amplifier with InP-based Two-storied ridge Structure 27

Characteristics of GaInAsP/SOI Hybrid Semiconductor Optical ...

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27th OptoElectronics and Communications Conference/International Conference on Photonics in Switching and Computing, OECC/PSC 2022

作者： Makihara, Yutaka Nishiyama, Nobuhiko Kikuchi, Takehiko Hiratani, Takuo Fujiwara, Naoki Inoue, Naoko Nitta, Toshiyuki Eissa, Moataz Mitarai, Takuya Wang, Yuning Oiso, Yoshitaka Amemiya, Tomohiro Yagi, Hideki Dept. of Electrical and Electronic Engineering Tokyo Institute of Technology Meguro-ku152-8550 Japan Institute of Innovative Research Tokyo Institute of Technology Meguro-ku152-8550 Japan Sumitomo Electric Industries Inc. Yokohama Works Transmission Devices R&d Labs 1 Taya-cho Sakae-ku Yokohama Kanagawa Yokohama244-8588 Japan Optoelectronics Industry and Technology Development Association Sumitomo Edogawabashiekimae Bldg.7F 1-20-10 Sekiguchi Bunkyo-ku Tokyo112-0014 Japan

GaInAsP/SOI hybrid SOAs with the InP-based two-storied ridge structure fabricated by the room temperature surface activated bonding were demonstrated. The wavelength dependence of gain was within 4.0 dB for the wavele... 详细信息

ISBN: (数字)9784885523366

ISBN: (纸本)9784885523366

关键词： Indium phosphide

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Numerical Simulation of Slotted Screen Plugging Mechanism Based on Cfd-dem Coupling

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SSrN 2022年

作者： deng, Fucheng Gao, Zhiwei Cao, Yanfeng deng, Junyu Shen, Xuefeng School of Mechanics Engineering Yangtze University Hubei Jingzhou434000 China CNOOC Research Institute Beijing100028 China CNPC Engineering Technology R&D Company Limited Tianjin300457 China China Petroleum Technology and Development Corporation Beijing100028 China

As the simplest and commonly used mechanical sand control method in well completion, slotted screen sand control is used for filling sand control, independent sand control in thermal production wells or geothermal wells. In order to explore the plugging mechanism of slotted screen and the factors affecting sand production during sand control, the CFd-dEM coupling method is used in this paper. The discrete element method is used to establish the model considering the physical properties of sand particles in the formation, and the fluid flow model is established combined with the finite volume method, and the full coupling solution of the two is realized and the model verification is completed. The effects of particle size distribution, sand concentration, slotted size and fluid velocity on slotted screen plugging are studied, and the plugging mechanism of slotted screen is revealed. The following research results are obtained. First, the retention form of sand particles at the screen gap is the fundamental factor affecting screen plugging. Sand bridging will have a certain probability of collapse, resulting in "false stability". Second, the proportion of larger diameter sand determines the formation time and stability of "sand bridge", and the proportion of smaller diameter sand determines the compactness of solid retention. Third, sand concentration is very important to control the plugging removal frequency of screen. Fourth, the gap size and fluid velocity affect the pressure difference on the screen surface and the stability of the "sand bridge". This study provides a reference for optimizing the selection and production control of slotted screen during the downhole sand control design. © 2022, The Authors. All rights reserved.

关键词： Sand

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Precisely engineered conjugated polyimide cathodes with dense redox-active carbonyl sites for superior lithium-ion battery performance

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Journal of Materials Chemistry A 2025年第23期13卷 17294-17307页

作者： Elnaggar, Mohamed A. dong, Nanxi Kang, Yongjun Liu, Bingxue Lin, daolei Tian, Guofeng Qi, Shengli Wu, dezhen State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Beijing100029 China Department of Chemistry Faculty of Science Benha University Benha13518 Egypt ENFI R&D Institute China ENFI Engineering Corporation No. 12 Fuxing Avenue Haidian District Beijing100038 China China Automotive Battery Research Institute Co. Ltd No. 11 Xingke Dong Street Yanqi Economic Development Zone Huairou District Beijing101407 China

Polyimide cathode materials have enticed tremendous attention as alternatives to transition-metal electrodes owing to their large theoretical capacity, structural diversity, low cost, and rapid reaction kinetics. Conversely, such imide electrodes still face a severe challenge to achieve their energy storage applications satisfactorily due to the insufficient utilization of their redox-active sites originating from their low electronic conductivities. Herein, four functionalized polyimide composites have been fabricated by virtue of an in situ polycondensation reaction between a newly synthesized benzophenone-benzoquinone-based diamine and commercial dianhydrides in the presence of a conductive Super C45 material for application as cathode materials in Li-ion batteries. Such innovative integration of carbonyl groups of benzophenone, benzoquinone, and diimide rings with the Super C45 material not only creates a stable porous structure with abundant accessible redox-active sites but also guarantees fast electron/ion diffusion. Consequently, our targeted PMQP-SP cathode delivers high capacities of 143 mA h g−1 at 0.2C and 122 mA h g−1 at 1C and attains better rate capability besides ultra-stable cycling performance with 85% capacity retention over 500 cycles at 2C. According to dFT calculations, the theoretical results are well consistent with the electrochemical performance of the synthesized composites. Generally, this work suggests an efficient strategy to design novel carbonyl-rich organic electrodes for next-generation green rechargeable batteries. © 2025 The royal Society of Chemistry.

关键词： Lithium-ion batteries

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