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direct measurement of near-bottom turbulence in deep ocean for predicting behavior of suspended particles in Sagami Bay and the Okinawa Trough, Japan

Direct measurement of near-bottom turbulence in deep ocean f...

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Oceans (Conference)

作者： Yasuo Furushima Hironori Higashi Tatsuo Fukuhara Naoki Furuichi Hiroyuki Yamamoto Research and Development (R&D) Center for Submarine Resources Japan Agency for Marine-Earth Science and Technology (JAMSTEC) Yokosuka Japan National Research Institute of Fisheries Engineering Japan Fisheries Research and Education Agency (FRA) Kamisu Japan

ISBN: (纸本)9781509064298;9780692946909

In this study, turbulent flows were measured using the Expendable Vertical Microstructure Profiler (VMP-X) at the hydrothermal fields in the Okinawa Trough (Iheya North field and Noho site) and Sagami Bay (off Itoh and at Ohmuro Caldera) to characterize the turbulence intensity. For each observation point, the turbulent flow data were successfully measured between the sea surface and the sea floor. In the vicinity of the sea floor off Itoh port, the energy dissipation rate (ε) was measured as 10~(-6) (W kg~(-1)). This value was equivalent to that frequently observed in the surface mixed layer. real-time current measurements are obtained from the Acoustic doppler Current Profiler (AdCP) at the real-time deep Seafloor Observatory off Hatsushima Island, which is operated by JAMSTEC. Strong northeastward flows at the time of turbulent flow measurement were confirmed by AdCP data. Such strong northeastward flows may intensify turbulence near the sea floor. It is important that we clarify the response with turbulent flow data and existing data in this way. As a result of the direct measurement of turbulent flow in the Okinawa Trough, the turbulent energy dissipation rate (ε) near the bottom was approximately 10~(-7) (W kg~(-1)). Turbulent flow was strong from the bottom to a height of around 20 m from the bottom, and water temperature slightly rose at the Noho site in the Okinawa Trough. This fluctuation may be due to the influence of hydrothermal venting. Therefore, the intensity of turbulence (ε: energy dissipation rate) may also be affected by the hydrothermal venting. However, the results obtained using the turbulent flow meter (VMP-X) are only a snapshot, and more in-situ observational data is necessary to understand the dynamics of the bottom mixed layer (turbulent flow). Therefore, data filing in consideration of spatiotemporal dynamics is still necessary.

关键词： Turbulent flow VMP-X Hydrothermal fields Energy dissipation rate Bottom mixed layer

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Study for further introduction of the Electronic Frequency converters to the Tokaido Shinkansen

Study for further introduction of the Electronic Frequency c...

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International Power Electronics Conference

作者： Toshimasa Shimizu Ken Kunomura Masahiko Kai Hiroki Miyajima Teruhisa Matsui General Technology Division Technology Research and Development Department Central Japan Railway Company Aichi Japan Construction Department Central Japan Railway Company Kanagawa Japan Railway system Division Toshiba Infrastructure systems & Solutions Corporation Kanagawa Japan Power System Solution and Distribution System R&D Department Toshiba Corporation Tokyo Japan

In the Tokaido Shinkansen, frequency conversion systems are used for unification of the feeding electric power frequency. For the base power, rotary frequency changers are used for these tolerances against inrush current or temporary heavy load current. Then, the frequency conversion equipment are mainly composed by the rotary frequency changers. In this report, studies are done for further introduction of the electronic frequency converters, replacing rotary frequency changers. And, progresses for replacements are realized by investigating controls, blocking and re-drive system, with reducing special rating.

关键词： Shinkansen Frequency converter Inrush current

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Optimizing Blendstock Composition and Ethanol Feedstock to reduce Gasoline Well-to-Pump CO 2 Emission

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Energy Procedia 2017年 105卷 3642-3647页

作者： Bo Zhang S. Mani Sarathy Amir F.N. Abdul-Manan King Abdullah University of Science and Technology Clean Combustion Research Center Thuwal 23955-6900 Saudi Arabia University of Oxford Chemical Engineering Engineering Science Oxford OX1 3PJ United Kingdom Strategic Transport Analysis Team Fuel Technology R&D Research & Development Center (R&DC) Saudi Aramco Dhahran 31311 Saudi Arabia

Lifecycle CO 2 emission of ethanol blended gasoline was simulated to investigate how fuel properties and composition affect overall emission. Fuel research octane number (rON), octane sensitivity and ethanol content (derived from sugarcane and corn) were varied in the simulations to formulate blended fuels that economically achieve target specifications. The well-to-pump (WTP) simulation results were then analyzed to understand the effects of fuel composition on emission. Elevated ethanol content displaces aromatics and olefins required in gasoline blendstock to reach a target fuel specification. The addition of greater sugarcane-based ethanol percentage in constant aromatics and olefins fuel reduces its WTP CO 2 emission. Corn-based ethanol blending does not offer CO 2 emission offset due to its high production emissions. The mixing of sugarcane-based with corn-based ethanol is shown to be a potentially effective method for achieving a blended fuel with a lower lifecycle CO 2 emission. Besides CO 2 emission, the total greenhouse gas (GHG) emission from land-use conversions (LUC), CH 4 , and N 2 O are also significant in determining the optimal fuel blend. Herein, we present preliminary results showing that total GHG emissions significantly increase when either corn or sugarcane ethanol is blended at even small percentages; detailed results will be addressed in future communications.

关键词： Corn-based ethanol lifecycle analysis ethanol blended gasoline CO 2 emission well-to-wheel emission

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A 510-ppi 8K x 4K LTPS TFT-LCd with 120-Hz Frame-rate driving 54

A 510-ppi 8K x 4K LTPS TFT-LCD with 120-Hz Frame-Rate Drivin...

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54th Annual SId Symposium, Seminar, and Exhibition 2016, display Week 2016

作者： Mochizuki, Kazuhide Hayashi, Hirotaka Nakamura, Takashi Kato, Hirofumi Oyama, Atsunori Okita, Mitsutaka Matsui, Yasuyuki Kimura, Hiroyuki Japan Display Inc. Ground Technology R&D Dept. Research & Development Center 3300 Hayano Chiba-ken Mobarashi297-86222 Japan

We have developed a 510[ppi] 8K4K LTPS TFT-LCd with 120[Hz] frame rate driving. High mobility of the TFT allows simple panel configuration. Shrinkage of the channel width and thinner insulator for the storage capacito... 详细信息

ISBN: (纸本)9781510832909

关键词： Thin film transistors

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Open data from the Third Observing run of LIGO, Virgo, KAGrA, and GEO

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Astrophysical Journal, Supplement Series 2023年第2期267卷 29-29页

作者： Abbott, r. Abe, H. Acernese, F. Ackley, K. Adhicary, S. Adhikari, N. Adhikari, r.X. Adkins, V.K. Adya, V.B. Affeldt, C. Agarwal, d. Agathos, M. Aguiar, O.d. Aiello, L. Ain, A. Ajith, P. Akutsu, T. Albanesi, S. Alfaidi, r.A. Al-Jodah, A. Alléné, C. Allocca, A. Almualla, M. Altin, P.A. Amato, A. Amez-droz, L. Amorosi, A. Anand, S. Ananyeva, A. Andersen, r. Anderson, S.B. Anderson, W.G. Andia, M. Ando, M. Andrade, T. Andres, N. Andrés-Carcasona, M. Andrić, T. Ansoldi, S. Antelis, J.M. Antier, S. Aoumi, M. Apostolatos, T. Appavuravther, E.Z. Appert, S. Apple, S.K. Arai, K. Araya, A. Araya, M.C. Areeda, J.S. Arène, M. Aritomi, N. Arnaud, N. Arogeti, M. Aronson, S.M. Arun, K.G. Asada, H. Ashton, G. Aso, Y. Assiduo, M. Assis de Souza Melo, S. Aston, S.M. Astone, P. Aubin, F. AultONeal, K. Babak, S. Badalyan, A. Badaracco, F. Badger, C. Bae, S. Bagnasco, S. Bai, Y. Baier, J.G. Baiotti, L. Baird, J. Bajpai, r. Baka, T. Ball, M. Ballardin, G. Ballmer, S.W. Baltus, G. Banagiri, S. Banerjee, B. Bankar, d. Baral, P. Barayoga, J.C. Barber, J. Barish, B.C. Barker, d. Barneo, P. Barone, F. Barr, B. Barsotti, L. Barsuglia, M. Barta, d. Barthelmy, S.d. Barton, M.A. Bartos, I. Basak, S. Basalaev, A. Bassiri, r. Basti, A. Bawaj, M. Bayley, J.C. Baylor, A.C. Bazzan, M. Bécsy, B. Bedakihale, V.M. Beirnaert, F. Bejger, M. Bell, A.S. Benedetto, V. Beniwal, d. Benoit, W. Bentley, J.d. Ben Yaala, M. Bera, S. Berbel, M. Bergamin, F. Berger, B.K. Bernuzzi, S. Beroiz, M. Berry, C.P.L. Bersanetti, d. Bertolini, A. Betzwieser, J. Beveridge, d. Bevins, N. Bhandare, r. Bhandari, A.V. Bhardwaj, U. Bhatt, r. Bhattacharjee, d. Bhaumik, S. Bianchi, A. Bilenko, I.A. Bilicki, M. Billingsley, G. Bini, S. Birnholtz, O. Biscans, S. Bischi, M. Biscoveanu, S. Bisht, A. Biswas, B. Bitossi, M. Bizouard, M.-A. Blackburn, J.K. Blair, C.d. Blair, d.G. Blair, r.M. Bobba, F. Bode, N. Boër, M. Bogaert, G. Boileau, G. Boldrini, M. Bolingbroke, G.N. Bonavena, L.d. Bondarescu, r. Bondu, F. Bonilla, E. Bonilla, G.S. Bonnand, r. Booker, P. Bork, r. Boschi, V. Bose, N. LIGO Laboratory California Institute of Technology Pasadena 91125 CA United States Graduate School of Science Tokyo Institute of Technology 2-12-1 Ookayama Meguro-ku Tokyo 152-8551 Japan Dipartimento di Farmacia Università di Salerno Salerno Fisciano I-84084 Italy INFN Sezione di Napoli Napoli I-80126 Italy OzGrav School of Physics & Astronomy Monash University Clayton 3800 VIC Australia The Pennsylvania State University University Park 16802 PA United States University of Wisconsin-Milwaukee Milwaukee 53201 WI United States Louisiana State University Baton Rouge 70803 LA United States OzGrav Australian National University Canberra 0200 ACT Australia Max Planck Institute for Gravitational Physics (Albert Einstein Institute) Hannover D-30167 Germany Leibniz Universität Hannover Hannover D-30167 Germany Inter-University Centre for Astronomy and Astrophysics Pune 411007 India University of Cambridge Cambridge CB2 1TN United Kingdom Instituto Nacional de Pesquisas Espaciais São Paulo São José dos Campos 12227-010 Brazil Cardiff University Cardiff CF24 3AA United Kingdom INFN Sezione di Pisa Pisa I-56127 Italy International Centre for Theoretical Sciences Tata Institute of Fundamental Research Bengaluru 560089 India Gravitational Wave Science Project National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Dipartimento di Fisica Università degli Studi di Torino Torino I-10125 Italy INFN Sezione di Torino Torino I-10125 Italy SUPA University of Glasgow Glasgow G12 8QQ United Kingdom OzGrav University of Western Australia Crawley 6009 WA Australia Univ. Savoie Mont Blanc CNRS Laboratoire d'Annecy de Physique des Particules - IN2P3 Annecy F-74000 France Università di Napoli “Federico II” Napoli I-80126 Italy University of Minnesota Minneapolis 55455 MN United States M

The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGrA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://***. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages. © 2023. The Author(s). Published by the American Astronomical Society.

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Application of generative autoencoder in de novo molecular design

arXiv

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arXiv 2017年

作者： Blaschke, Thomas Olivecrona, Marcus Engkvist, Ola Bajorath, Jürgen Chen, Hongming Hit Discovery Discovery Sciences Innovative Medicines and Early Development Biotech Unit AstraZeneca R&D Gothenburg Mölndal431 83 Sweden Bonn Aachen International Center for Information Technology BIT University of Bonn Dahlmannstrasse 2 Bonn53113 Germany

A major challenge in computational chemistry is the generation of novel molecular structures with desirable pharmacological and physiochemical properties. In this work, we investigate the potential use of autoencoder, a deep learning methodology, for de novo molecular design. Various generative autoencoders were used to map molecule structures into a continuous latent space and vice versa and their performance as structure generator was assessed. Our results show that the latent space preserves chemical similarity principle and thus can be used for the generation of analogue structures. Furthermore, the latent space created by autoencoders were searched systematically to generate novel compounds with predicted activity against dopamine receptor type 2 and compounds similar to known active compounds not included in the trainings set were identified. Copyright © 2017, The Authors. All rights reserved.

关键词： Computational chemistry

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Correction to: Considerations for Updates to ICH Q1 and Q5C Stability Guidelines: Embracing Current technology and risk Assessment Strategies

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The AAPS journal 2021年第6期23卷 118页

作者： Megan E McMahon Alexander Abbott Yelizaveta Babayan Jenny Carhart Chi-Wan Chen Elke debie Mingkun Fu Cherokee Hoaglund-Hyzer Andrew Lennard Hanlin Li Tony Mazzeo Lori McCaig Sylvine Pischel Fenghe Qiu dennis Stephens robert Timpano debra Webb Chad Wolfe Kayla Woodlief Yan Wu Pfizer Inc. Eastern Point Road Groton Connecticut 06340 USA. megan.mcmahon@***. Oral Product Development Pharmaceutical Technology & Development Operations AstraZeneca Silk Road Business Park Macclesfeld Cheshire SK10 2NA UK. Eli Lilly & Company Lilly Corporate Center Indianapolis Indiana 46285 USA. Takeda Pharmaceuticals Inc. 40 Landsdowne Street Cambridge Massachusetts 02139 USA. Pfizer Inc. 8455 Colesville Rd Silver Spring Maryland 20910 USA. Janssen R&D A Division of Janssen Pharmaceutica NV Turnhoutseweg 302340 Beerse Belgium. Sunovion Pharmaceutical Inc. 84 Waterford Drive Marlborough Massachusetts 01752 USA. Amgen Ltd. 1 Uxbridge Business Park Sanderson Road Uxbridge UB8 1DH UK. Vertex Pharmaceuticals 50 Northern Avenue Boston Massachusetts 02210 USA. Bristol Myers Squibb 1 Squibb Drive New Brunswick New Jersey 08903 USA. Seagen Inc. 21823 30th Drive SE Bothell Washington 98021 USA. GlaxoSmithKline Great West Road Brentford TW8 9GS Middlesex UK. Boehringer Ingelheim 900 Ridgebury Road Ridgefeld Connecticut 06877 USA. AbbVie 1 N Waukegan Road North Chicago Illinois 60064 USA. Pfizer Inc. Eastern Point Road Groton Connecticut 06340 USA. 225 Binney Street Cambridge Massachusetts USA. Merck & Co. 2000 Galloping Hill Road Kenilworth New Jersey 07033 USA.

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Mechanical behaviors of cement systems in different conditions

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Natural Gas Industry B 2017年第3期4卷 212-216页

作者： Zheng, Youzhi Xu, Bingqing Pu, Junhong Mu, Naiqu Wang, Bin Li, Ming Engineering Technology Research Institute PetroChina Southwest Oil & Gas Field Company Guanghan 618300 Sichuan China Engineering Technology Research Institute National Energy High Sulfur Exploitation R&D Center Guanghan 618300 Sichuan China Engineering Division PetroChina Southwest Oil & Gas Field Company Chengdu 610051 Sichuan China Northeast Sichuan Division PetroChina Southwest Oil & Gas Field Company Chengdu 610051 Sichuan China Sichuan Changning Natural Gas Development Ltd. PetroChina Southwest Oil & Gas Field Company Chengdu 610051 Sichuan China School of Material Science and Engineering Southwest Petroleum University Chengdu 610500 Sichuan China

At present, the mechanical testing on the ductility of cement sheath is faced with multiple technical difficulties. In this paper, numerical simulation and laboratory evaluation were adopted to compare the mechanical performance of typical elastic, flexible, ductile and neat cement systems at home and abroad by different loading rates, value range of stress–strain curve, confining pressure and temperature. It is shown that when the loading rate is lower, the stress–strain curve of set cement is not smooth, but distorted, and the stress cannot be responded in time;that when the loading rate is higher, the stress–strain curve of set cement is smooth, and the yield stage is remarkable, indicating that higher loading rate can reflect the yield strain behavior of set cement more truly;that the recommended Young's modulus range of set cement should be changed based on the actual downhole conditions;that temperature has more effect on yield stress and ultimate strain, but less effect on elastic modulus;that confining pressure has more effect on ultimate stress and ultimate strain, but less effect on elastic modulus;and that when the confining pressure is lower and temperature is higher, the yield stage of set cement is more remarkable. It is concluded that these mechanical behaviors of cement system in different conditions provide a technical support for understanding the mechanical essence of downhole cement sheath and exploring the mechanical integrity of cement sheath and even that of the whole wellbore. © 2017 Sichuan Petroleum Administration

关键词： Confining pressure Loading rate Mechanical testing on ductility of cement sheath Set cement Stress–strain Temperature Well cementing

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development of Next Generation Flip Chip Interconnection technology Using Homogenized Laser-Assisted Bonding

Development of Next Generation Flip Chip Interconnection Tec...

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Electronic Components and technology Conference (ECTC)

作者： Yanggyoo Jung dongsu ryu Minho Gim Choonghoe Kim Yunseok Song Jinyoung Kim Juhoon Yoon Choonheung Lee Package Development Team R&D Center Amkor Technology Korea Inc. Seoul Korea

Conventional flip chip technologies such as the mass reflow (Mr) process and the thermal compression bonding (TCB) process are commonly used technologies in the micro assembly field. However, there is a continuous need for next generation interconnection technology to achieve a low form factor with increasing die and substrate complexities. Moreover, very thin 3d integrated packages and 2.5d packages with thin interposer die promise advanced interconnection technologies for mobile and wearable applications. With this point of view, the most important factor in interconnection is optimal thermal energy control for soldering. However, a conventional Mr process cannot provide any selectivity and controlled thermal energy transferring with the traditional convection reflow. Its high thermal budget makes warpage an issue, aside from other side effects. To overcome the Mr process problems, recent researches and industries have focused on developing a TCB process with non-conductive paste (NCP) or non-conductive film (NCF) due to TCB's unique advantages of low mechanical and thermal stress. However, the productivity of the TCB process is not comparably to the conventional process. Laser-assisted bonding (LAB) with beam homogenizer is considered to be the next generation interconnection technology due to its excellent thermal selectivity, extremely fast ramping up speed with purely controlled wavelength. This LAB process offers a very stable interconnection quality as well as robust functional and reliability result. Interestingly, it also achieves excellent results with thin coreless substrate due to its selective heating area availability. This paper will discuss the laser heating mechanism, multi-chip & component bonding availability and advantage of LAB from an assembly industrial perspective.

关键词： Laser beams Heating Silicon Bonding Absorption Flip-chip devices Substrates

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Obtaining and characterisation of high entropy alloys used for medical applications

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IOP Conference Series: Materials Science and Engineering 2019年第1期572卷

作者： V Geantă I Voiculescu r Ştefănoiu M Codescu H Kelemen G Pavel A Vlădescu V A Sandu POLITEHNICA University of Bucharest 313 Splaiul Independenţei 060042 Bucharest Romania National Institute for R&D in Electrial Engineering ICPE-CA 313 Splaiul Unirii District 3 030138 Bucharest Romania University of Medicine Pharmacy Science and Technology of Targu Mures Gheorghe Marinescu 38 540139 Tirgu Mures Romania The University of Agricultural Sciences and Veterinary Medicine Iaşi 3 Mihail Sadoveanu Alley 700490 Iaşi Romania National Institute for Research and Development in Optoelectronics INOE 2000 409 Atomiştilor street 077125 Măgurele Romania Gheorghe Asachi Technical University of Iasi 67 Dimitrie Mangeron Blvd. 700050 Iasi Romania

The experimental CrFeMoNbTaTiZr alloys were designed based on the extremely low bio-toxicity of the chemical elements. They are currently used as a basis for alloying of classical alloys used in medical device manufacturing. From this alloying system, were obtained in a Vacuum Arc remelting (VAr) equipment six alloys: CrFeMoNbTaTi, CrFeMoNbTaZr, CrFeMoTaTiZr, CrFeTaNbTiZr, CrTaNbTiZrMo and FeTaNbTiZrMo. The microstructural analysis of the obtained alloys have been performed by optical and SEM microscopy. The microhardness tests show results in the range of 575 – 1337 HV0.2 / 10. In order to improve the mechanical properties heat treatment procedures have been applied.

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