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Cover Feature: Magnetic Supraparticles as Identifiers in Single-Layer Lithium-Ion Battery Pouch Cells (ChemSusChem 6/2025)

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ChemSusChem 2025年第6期18卷

作者： Sara Li deuso Simon Ziegler daniel Weber Felix Breuer daniel Haddad Stephan Müssig Andreas Flegler Guinevere A. Giffin Karl Mandel Department of Chemistry and Pharmacy Friedrich-Alexander University Erlangen-Nürnberg (FAU) Egerlandstraße 1 91058 Erlangen Germany Fraunhofer R&D Center Electromobility Fraunhofer Insitute for Silicate Research (ISC) Neunerplatz 2 97082 Würzburg Germany Development Center X-ray Technology (EZRT) Fraunhofer Institute for Integrated Circuits (IIS) Am Hubland 97074 Würzburg Germany

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WCN23-0281 KIdNEY TrANSCrIPTOMICS PATTErNS PrEdICT rAPId PrOGrESSION OF dIABETIC KIdNEY dISEASE

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Kidney International reports 2023年第3期8卷 S190-S190页

作者： d. ACOBA A. Levin A. Witasp P. Greasley J. Mölne J. Nyström A. Wernerson A. reznichenko AstraZeneca Translational Science & Experimental Medicine- Research and Early Development- Cardiovascular- Renal and Metabolism- BioPharmaceuticals R&D Gothenburg Sweden Université Paris Cité Institut National de la Santé et de la Recherche Médicale INSERM U1151- Institut Necker Enfants Malades INEM Paris France Karolinska Institutet Department of Clinical Science- Intervention and Technology- Division of Renal Medicine Stockholm Sweden AstraZeneca Early Clinical Development- Research and Early Development- Cardiovascular- Renal and Metabolism- BioPharmaceuticalss R&D Gothenburg Sweden University of Gothenburg Department of Laboratory Medicine- Institute of Biomedicine- Sahlgrenska Academy Gothenburg Sweden University of Gothenburg Department of Physiology- Institute of Neuroscience and Physiology- Sahlgrenska Academy Gothenburg Sweden

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Biowaste to Biochar: A Techno-Economic and Life Cycle Assessment of Biochar Production from Food-Waste digestate and its Agricultural Field Application

SSRN

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SSrN 2023年

作者： Gamaralalage, disni rodgers, Sarah Gill, Andy Meredith, William Bott, Tom West, Helen Alces, Jessica Snape, Colin McKechnie, Jon Sustainable Process Technologies Research Group Faculty of Engineering The University of Nottingham NottinghamNG7 2RD United Kingdom R&D manager CPL Industries Energy Technology Building Jubilee Campus The University of Nottingham NottinghamNG7 2TU United Kingdom Chemical and Environmental Engineering Jubilee Campus The University of Nottingham NottinghamNG8 1BB United Kingdom School of Biosciences Sutton Bonington Campus The University of Nottingham LeicestershireLE12 5RD United Kingdom Strategy & Development Severn Trent Green Power The Stables Radford Chipping NortonOX7 4EB United Kingdom

Biochar has high potential for long-term atmospheric carbon storage in terrestrial environments, contributing to meet UK and global greenhouse gas emission reduction targets. This study investigates greenhouse gas emissions and techno-economics associated with biochar produced from anaerobic digestate using hydrothermal carbonisation with post carbonisation at higher temperatures. While digestates are challenging to valorise, owing to high moisture contents, these low-value feedstocks have steady availability with minimal competition for other applications. The study scope includes food-waste digestate supply, stable biochar production, agricultural field application including co-benefits, and transportation activities. Minimising digestate transport through co-location of biochar production with anaerobic digestion demonstrated greenhouse gas mitigation costs of © 2023, The Authors. All rights reserved.

关键词： Greenhouse gases

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Graptolite-derived Organic Matter and Pore Characteristics in the Wufeng-Longmaxi Black Shale of the Sichuan Basin and its Periphery

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Acta Geologica Sinica(English Edition) 2019年第4期93卷 982-995页

作者： WU Jin ZHOU Wen SUN Shasha ZHOU Shangwen SHI Zhensheng State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu 610059SichuanChina Research Institute of Petroleum Exploration and Development PetroChinaBeijing 100083China National Energy Shale Gas R&D(Experiment)Centre Langfang 065007HebeiChina PetroChina Unconventional Oil&Gas Key Laboratory Langfang 065007HebeiChina

A key target of shale gas exploration and production in China is the organic-rich black shale of the Wufeng Formation-Longmaxi Formation in the Sichuan Basin and its *** set of black shale contains abundant graptolites,which are mainly preserved as flattened rhabdosomes with carbonized periderms,is an important organic component of the ***,few previous studies had focused on the organic matter(OM)which is derived from graptolite and its pore *** particular,the contributions of graptolites to gas generation,storage,and flow have not yet been *** this study,focused ion beam-scanning electron microscope(FIB-SEM)was used to investigate the characteristics of the graptolite-derived OM and the micro-nanopores of graptolite *** results suggested that the proportion of OM in the graptolite was between 19.7%and 30.2%,and between 8.9%and 14.4%in the surrounding *** total organic carbon(TOC)content of the graptolite was found to be higher than that of the surrounding rock,which indicated that the graptolite played a significant role in the dispersed organic *** types of pores were developed in the graptolite periderm,including organic gas pores,pyrite moulage pores,authigenic quartz moldic pores,and *** well-developed micro-nano pores and fractures had formed an interconnected system within the graptolites which provided storage spaces for shale *** stacked layers and large accumulation of graptolites resulted in lamellation fractures openning easily,and provided effective pathways for the gas flow.A few nanoscale gas pores were observed in the graptolite-derived OM,with surface porosity lie in 1.5%–2.4%,and pore diameters of 5–20 *** sapropel detritus was determined to be rich in nanometer-sized pores with surface porosity of 3.1%–6.2%,and pore diameters of 20–80 *** to the small amount of hydrocarbon generation of the graptolite,supporting the overlying pressure was difficult,which caused

关键词： graptolite pore structure shale gas Wufeng-Longmaxi Formations Sichuan Basin

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residue super-resolution convolutional neural network based complexity reduction for H.266 VVC intra-coding

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ICT Express 2025年

作者： dhanalakshmi, A. Balaji, L. raja, C. Giri, Jayant Alrashoud, Mubarak Department of ECE Panimalar Engineering College Chennai India Department of ECE Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and Technology Chennai India Department of Mechanical Engineering Yeshwantrao Chavan College of Engineering Nagpur India Division of Research and Development Lovely Professional University Phagwara India Chair of Smart Technologies College of Computer and Information Sciences King Saud University Riyadh Saudi Arabia

Versatile Video Coding (VVC) promised to provide the same video quality as HEVC with 50 % bitrate reduction, which was introduced in 2020. Our suggested method for VVC Intra-coding is residue super-resolution convolutional neural network (rSr-CNN) utilizing downsampling and upsampling procedures. We present an effective complexity reduced VVC intra-coding scheme based on residue Sr-CNN. reducing an original video's resolution in both the vertical and horizontal directions is all that is required to execute down sampling. Increasing the video dimensions for improved visual quality, convolutional neural networks are utilized in the upsampling process to create residue super-resolution. Specifically, for every block, we train a CNN model to perform residue Sr after downsampling and compressing the residue at low resolution, and then we carry out motion estimation (ME) and motion compensation (MC) to extract the residue. Using the MC prediction signal, a new residue Sr-CNN is designed. Additionally, this work comprehensively examines the complexity and performance of VVC intra-coding tools and integrates them with the residue Sr-CNN method. The experiments demonstrate a substantial time savings of 40 % in encoding with BdBr coding gains of 4.2 %, and 2.9 % in AI and rA configurations respectively. © 2025 The Author(s)

关键词： Intra-coding Low complexity PSNr residue super-resolution convolutional neural network VVC

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Nucleate boiling heat transfer characteristics of non-azeotropic refrigerant-lubricant mixture on different modified surfaces

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Applied Thermal Engineering 2025年 277卷

作者： dandan Su Qifan Wang Jing Li Minxia Li Chaobin dang Xuetao Liu Chengjuan Yang State Key Laboratory of Engines Tianjin University Tianjin 300350 China Tianjin Key Laboratory of Refrigeration Technology Tianjin University of Commerce Tianjin 300134 China Graduate School of Engineering University of Fukui Fukui City 910-8507 Japan Hisense Research and Development (R&D) Center Qingdao 266100 China Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education Tianjin University Tianjin 300350 China

Investigating the boiling heat transfer mechanisms of non-azeotropic refrigerant-lubricant mixture on modified surfaces is crucial for optimizing the design of refrigeration and heat pump systems. In this study, the nucleate boiling heat transfer characteristics of r454B-POE and r32-POE mixtures on modified surfaces are measured with the oil concentrations of 1 wt%, 3 wt%, and 5 wt%. The modified surfaces include microcolumn surface (MS), femtosecond laser-processed micro-nano composite surface (FLMS), oxidation-etched micro-nano composite surface (OEMS), and micro-nano composite surface modified with low surface energy substance (MS-LSE). The results indicate that the influence of lubricant on the boiling heat transfer performance of r454B is relatively small compared to that of r32. On the MS-LSE, the presence of lubricant improves the performance of r454B at low heat flux below 170 kW/m 2 . However, on the other modified surfaces, the presence of lubricant negatively impacts heat transfer performance. The negative effect of lubricant on the heat transfer on OEMS is the largest. As the oil concentration increases, the negative impact of the lubricant becomes more pronounced. At a wall superheat of 10 K and an oil concentration of 1 wt%, the heat fluxes of the r32-POE and r454B-POE mixtures on the OEMS are 75 kW/m 2 and 114 kW/m 2 , respectively. In contrast, on the MS-LSE, the heat fluxes of r32-POE and r454B-POE mixtures are 155 kW/m 2 and 750 kW/m 2 , respectively. These findings provide a theoretical basis for optimizing heat exchanger design in refrigeration and heat pump systems.

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Control strategy and methods for continuous direct compression processes

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Asian Journal of Pharmaceutical Sciences 2021年第2期16卷 253-262页

作者： Yasuhiro Suzuki Hirokazu Sugiyama Manabu Kano ryutaro Shimono Gosuke Shimada ryoichi Furukawa Eichi Mano Keiichi Motoyama Tatsuo Koide Yasuhiro Matsui Kazuki Kurasaki Issei Takayama Shunin Hikage Noriko Katori Masahiko Kikuchi Hiroshi Sakai Yoshihiro Matsuda Formulation Technology Research Laboratories Daiichi Sankyo Co.Ltd.Kanagawa 254-0014Japan Department of Chemical System Engineering The University of TokyoTokyo 113-8656Japan Department of Systems Science Kyoto UniversityKyoto 606-8501Japan CMC Sciences Department Regulatory Affairs DivisionR&D DivisionJanssen Pharmaceutical K.K.Tokyo 101-0065Japan EuroTechno Ltd. Kanagawa 223-0057Japan Pharmaceutical Research Department Mitsubishi Tanabe Pharma CorporationOsaka 532-8505Japan Chemical Products CMC Regulatory Affairs Area Japan DevelopmentMSD K.K.Tokyo 102-8667Japan Graduate School of Pharmaceutical Sciences Kumamoto UniversityKumamoto 862-0973Japan Division of Drugs National Institute of Health SciencesKawasaki 210-9501Japan Technology Research&Development Sumitomo Dainippon Pharma Co.Ltd.Osaka 564-0053Japan Formulation Development Department Chugai pharmaceutical Co.Ltd.Tokyo 115-8543Japan Office of New Drug IV Pharmaceuticals and Medical Devices AgencyShin-Kasumigaseki Bldg.Tokyo 100-0013Japan Office of Generic Drugs Pharmaceuticals and Medical Devices AgencyShin-Kasumigaseki Bldg.Tokyo 100-0013Japan KOKANDO Co. Ltd.Toyama 930-8580Japan Pharmaceuticals and Medical Devices Agency Shin-Kasumigaseki Bldg.Tokyo 100-0013Japan

We presented a control strategy for tablet manufacturing processes based on continuous direct *** work was conducted by the experts of pharmaceutical companies,machine suppliers,academia,and regulatory authority in *** different items in the process,the component ratio and blended powder content were selected as the items requiring the control method specific to continuous manufacturing different from the conventional batch *** control and management of the Loss in Weight(LIW)feeder were deemed the most important,and the residence Time distribution(rTd)model were regarded effective for setting the control range and for controlling of the LIW *** on these ideas,the concept of process control using rTd was summarized.

关键词： Continuous manufacturing Solid drug products Process control residence time distribution Loss in weight feeder regulatory science

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A hybrid Merec-Mabac approach for 3d printer nozzle material selection

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AIP Conference Proceedings 2024年第1期3217卷

作者： Prabhukumar Sellamuthu Kanak Kalita Ajay Kumar Jasgurpeet Singh Chohan Sarita rathee Yogender Kumar Sharma Department of Mechanical Engineering Presidency University Bengaluru India Department of Mechanical Engineering Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology Avadi India Department of Mechanical Engineering School of Engineering & Technology JECRC University Jaipur - 303 905 India Department of Mechanical Engineering and University Centre for Research & Development Chandigarh University Mohali India Department of Electronics and Communication Engineering School of Engineering & Technology JECRC University Jaipur - 303 905 India Manipal University Jaipur-303007 Rajasthan India

In this paper a multi-criteria decision-making (MCdM) method for selecting the optimal material for 3d printer nozzles is presented. Nine different criteria namely, density, thermal conductivity, corrosion resistance, hardness, wear resistance, cost of the nozzle material, yield strength, ultimate tensile strength and machinability are considered in this study. The study systematically evaluates nozzle material options and provides a comprehensive decision-making framework for 3d printer manufacturers and users. MEthod based on the removal Effects of Criteria (MErEC) is used as the weight allocation method. It is compared with other popular weight allocation methods like mean weight methods, entropy method and CrITIC method. The multi-criteria evaluation of the various nozzle materials is carried out using multi-attributive border approximation area comparison (MABAC) method. It is observed that MErEC-MABAC lists Aluminium 7075-T6 (A7) and Tungsten carbide (A4) as the best and worst alternative respectively. Further, the preference ranking of nozzle material by mean-MABAC and CrITIC-MABAC methods are seen to be almost identical.

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OncoEnrichr: cancer-dedicated gene set interpretation

arXiv

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arXiv 2021年

作者： Nakken, Sigve Gundersen, Sveinung Bernal, Fabian L.M. Polychronopoulos, dimitris Hovig, Eivind Wesche, Jørgen Department of Tumor Biology Institute for Cancer Research Oslo University Hospital Norway Centre for Cancer Cell Reprogramming Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway Centre for Bioinformatics Department of Informatics University of Oslo Norway University Center for Information Technology University of Oslo Norway Early Data Science and Computational Oncology Research and Early Development Oncology R&D AstraZeneca Cambridge United Kingdom

Genome-scale screening experiments in cancer produce long lists of candidate genes that require extensive interpretation for biological insight and prioritization for follow-up studies. Interrogation of gene lists frequently represents a significant and time-consuming undertaking, in which experimental biologists typically combine results from a variety of bioinformatics resources in an attempt to portray and understand cancer relevance. As a means to simplify and strengthen the support for this endeavor, we have developed oncoEnrichr, a flexible bioinformatics tool that allows cancer researchers to comprehensively interrogate a given gene list along multiple facets of cancer relevance. oncoEnrichr differs from general gene set analysis frameworks through the integration of an extensive set of prior knowledge specifically relevant for cancer, including ranked gene-tumor type associations, literature-supported proto-oncogene and tumor suppressor gene annotations, target druggability data, regulatory interactions, synthetic lethality predictions, as well as prognostic associations, gene aberrations, and co-expression patterns across tumor types. The software produces a structured and user-friendly analysis report as its main output, where versions of all underlying data resources are explicitly logged, the latter being a critical component for reproducible science. We demonstrate the usefulness of oncoEnrichr through interrogation of two candidate lists from proteomic and CrISPr screens. oncoEnrichr is freely available as a web-based workflow hosted by the Galaxy platform (https://***), and can also be accessed as a stand-alone r package (https://***/sigven/oncoEnrichr). © 2021, CC BY-NC-SA.

关键词： Tumors

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research and application of supramolecular gel plugging agent in abnormal pressure reservoir

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Journal of Physics: Conference Series 2021年第1期2045卷

作者： B Baletabieke Y X Gu T Zhou d X duan J T Liu X J Kong F Qian W J Li Z Zhong Y Xiang N Jing J Y Li CNPC Engineering Technology R&D Company Limited Beijing 102206 China China National Oil and Gas Exploration and Development Corporation Beijing 100034 China

The Aktobe project is the largest oil and gas producing area of PetroChina in Central Asia. However, after years of exploitation, the pressure of the reservoir has dropped, making it difficult to increase the production of a single well. Both the Kenkyak block and North Troyes block of the project have induced fractured leakage, and frequent leakage affects safe and efficient drilling and completion operations and production. Therefore, the research on leakage prevention and control technology is very necessary. This article focuses on the characteristics of the cracks in the high-pressure area of the Kenkyak block and the cracks in the low-pressure area of the North Troyes block. Aiming at the fracture characteristics of the high-pressure zone in the Kenkyak block and the low-pressure zone in North Troyes block, and taking advantage of the synergistic effect of supramolecules, a supramolecular plugging-while-drilling agent was developed based on the deformable fiber composite gel. It forms a strong adhesion plugging layer on the inner wall of the leakage channel through the strong adhesion force, and it achieves a good plugging effect. The 300-500md sand disc bearing pressure could reach 700psi when adding 3% agent, and the bearing pressure of 3-5d permeability sand disc could reach above 450psi. A supramolecular static plugging agent was also developed based on the dilatant gel. It is rich in strong shear reversible gel with supramolecular structure, which guarantees its pumpability and plugging performance. The effective rate of one-time plugging is over 80%, and the viscosity is greatly reduced after the gel is broken for 72hr, which benefits the reservoir protection.

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