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In this study, a glassy carbon electrode (GCE) modified with a vertically aligned ar.a. of multiwalled carbon nanotubes (MWCNTs) was fabricated via a temperature-controlled sol-gel method. The vertically aligned MWCNT structure significantly enhances the electrode's sur.a.e modification efficiency, offering superior electrochemical perfor.a.ce compared to conventional methods. The resulting MWCNT ar.a.-modified GCE demonstrates excellent selectivity by clearly differentiating the anodic oxidation potentials of dopamine (DA) and uric acid (UA), even in complex biological matrices. To further improve the electr.a.tive properties, the modified electrode was pre-tr.a.ed with ethanol and acetone prior to electrochemical measurements. remar.a.ly, this pre-tr.a.ment enabled the detection of an additional two-electron oxidation process during dopamine oxidation, associated with the conversion of 5,6-dihydroxyindole to indole-5,6-quinone—a feature not typically observed in other CNT-based electrodes. The optimized sensor exhibited high sensitivity and selectivity for the simultaneous detection of DA and UA in human serum and urine samples, achieving recovery rates ranging from 95% to 110%. These results highlight the potential of the sol-gel fabricated MWCNT ar.a.-GCE as an efficient and reliable platform for.a.vanced biosensing applications.
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版权所有:内蒙古大学图书馆 技术提供:维普资讯• 智图
内蒙古自治区呼和浩特市赛罕区大学西街235号 邮编: 010021
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