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Association of Metabolic Dysfunction-Associated Steatotic Liver Disease With Sudden Sensorineural Hearing Loss Among Older Adults

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Laryngoscope Investigative Otolaryngology 2025年第3期10卷 e70156页

作者： Kang, Eun Seok Jang, Seohui Kim, Hye Jun Kim, Kyuwoong Sha, Meng Oh, Yun Hwan Suh, Michelle J. Jeong, Seogsong Department of Biomedical Informatics Korea University College of Medicine Seoul South Korea Department of Biomedical Science CHA University Pocheon South Korea Department of Biomedical Sciences Seoul National University College of Medicine Seoul South Korea National Cancer Control Institute National Cancer Center Goyang South Korea Graduate School of Cancer Science and Policy National Cancer Center Goyang South Korea Department of Liver Surgery Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China Department of Family Medicine Chung-Ang University Gwangmyeong Hospital Chung-Ang University College of Medicine Gwangmyeong-si South Korea Department of Otorhinolaryngology Jeju National University Hospital Jeju National University College of Medicine Jeju South Korea Biomedical Research Center Korea University Guro Hospital Seoul South Korea

Objectives: This study examined the association between metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of sudden sensorineural hearing loss (SSNHL) in elderly individuals. Methods: A population-based cohort study using the Korean National Health Insurance Service-Senior cohort included 189,623 individuals aged 65 and older, categorized as non-SLD or MASLD. Cox proportional hazards regression and Fine-Gray subdistribution hazard models were used to evaluate the risk of SSNHL and Ménière's disease, considering all-cause mortality as a competing event. Results: Baseline characteristics showed that MASLD participants had higher metabolic dysfunction markers, including elevated body mass index, waist circumference, and blood pressure, compared to the non-SLD group. During 9 years of follow-up, 3803 SSNHL events occurred in the MASLD group, with an incidence rate of 2.44 per 1000 person-years. After inverse probability of treatment weighting, MASLD was associated with a significantly increased risk of SSNHL (adjusted hazard ratio: 1.05, 95% CI: 1.00–1.10;p = 0.039;subdistribution hazard ratio: 1.06, 95% CI: 1.01–1.11;p = 0.016). Conclusion: MASLD is associated with an increased risk of SSNHL. This study provides evidence supporting a metabolic influence on auditory health, warranting further investigation into the liver-ear axis. Level of Evidence: Step 3 (Level 3*)—Cohort study. © 2025 The Author(s). Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society.

关键词： Meniere's disease metabolic dysfunction-associated steatotic liver disease older adults sudden sensorineural hearing loss

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Color holographic display based on shifted and scaled fractional fourier transform 21

Color holographic display based on shifted and scaled fracti...

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21st International Display Workshops 2014, IDW 2014

作者： Xia, Jun Chang, Chenliang Jiang, Yanqiao Lei, Wei Xie, Yi Kang, Mingwu Zhang, Qiuzhi Display Center Department of Electronic Science and Engineering Southeast University Nanjing Jiangsu210096 China Science and Technology on Electro-optic Control Laboratory Luoyang471009 China

ISBN: (纸本)9781510827790

We propose a method of calculating the color hologram for color holographic display. Three phase-only holograms of red, green and blue component of color image are calculated by using the shifted and scaled fractional Fourier transfonv. The spatial samplings rate both in the hologram plane and the image plane are not constrained by the Nyquist sampling theory, so the problem of chromatic aberration caused by different wavelengths in the reconstruction is solved. The zero order diffraction can also be eliminated in the fractional Fourier transform optical system. © 2014 . Society for Information Display. All rights reserved.

关键词： Holograms

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Molecular ecological networks reveal the spatial-temporal variation of microbial communities in drinking water distribution systems

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Journal of Environmental sciences 2023年第2期124卷 176-186页

作者： Zibo Jing Zedong Lu Zhinan Zhao Wenfeng Cao Weibo Wang Yanchu Ke Xiaohui Wang Wenjun Sun Beijing Engineering Research Center of Environmental Material for Water Purification College of Chemical EngineeringBeijing University of Chemical TechnologyBeijing 100029China School of Environment Tsinghua UniversityBeijing 100084China Research Institute for Environmental Innovation(Suzhou)Tsinghua Suzhou 215163China State Key Joint Laboratory of Environmental Simulation and Pollution Control College of Environmental Sciences and EngineeringPeking UniversityBeijing 100871China

Microbial activity and regrowth in drinking water distribution systems is a major concern for water service ***,previous studies have focused on the microbial composition and diversity of the drinkingwater distribution systems(DWDSs),with little discussion on microbial molecular ecological networks(MENs)in different water supply *** analysis explores the potentialmicrobial interaction and the impact of environmental stress,to explain the characteristics of microbial community *** this study,the random matrix theory-based network analysis was employed to investigate the impact of seasonal variation including water source switching on the networks of three DWDSs that used different disinfection *** results showed that microbial interaction varied slightly with the seasons but was significantly influenced by different ***,identified as key species,play an important role in the *** UV-chlorine disinfection can effectively reduce the size and complexity of the network compared to chlorine disinfection alone,ignoring seasonal variations,which may affect microbial activity or control microbial regrowth in *** study provides new insights for analyzing the dynamics of microbial interactions in DWDSs.

关键词： Drinking water distribution system Molecular ecological network Water source switch UV-chlorine combined disinfection

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Analyzing effect of distraction caused by dual-tasks on sharing of brain resources using SOM

Analyzing effect of distraction caused by dual-tasks on shar...

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2010 6th IEEE World Congress on Computational Intelligence, WCCI 2010 - 2010 International Joint Conference on Neural Networks, IJCNN 2010

作者： Wang, Yu-Kai Pal, Nikhil R. Lin, Chin-Teng Chen, Shi-An Department of Computer Science Brain Research Center National Chiao-Tung University Taiwan Electronics and Communication Sciences Unit Indian Statistical Institute India Department of Electrical and Control Engineering Brain Research Center National Chiao-Tung University Taiwan

ISBN: (纸本)9781424469178

Drivers' distraction is widely recognized as a leading cause of car accidents. To investigate the distracting effect of dual-tasks involving driving and answering mathematical equations in the stimulus onset asynchrony (SOA) conditions, we design five different cases: two cases involving single-tasks and three cases involving dual-tasks. We have found that there is no statistically significant change in the behavioral data among the three dual-tasks. This raises an important question - is there any detectable effect of the dual tasks on the brain waves? To answer this, we use the Self-Organizing Map (SOM) to recognize the changes, if any, in the Electroencephalography (EEG) dynamics associated with such dual-tasks. Our SOM analysis based on independent components corresponding to EEG signals extracted from Frontal and Motor areas revealed that single- and dual-tasks have distinguishable signatures in the EEG signals. Specifically, each of the two single-task conditions is clustered in a distinct spatial area of the map. Two of the dual-tasks also exhibit distinct spatial clusters, while the third case although shows differences from the other two, the neurons corresponding to this case are sub-clustered reflecting the fact that different subjects may give different priorities to the tasks when confronted with two tasks simultaneously. SOM-based exploratory analysis reveals the existence of distinct EEG signatures among the distracting and non-distracting tasks, although there is no any noticeable difference in the behavioral data among these cases. © 2010 IEEE.

关键词： Self organizing maps

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research on frequency control strategy of combined wind- energy storage system 2

Research on frequency control strategy of combined wind- ene...

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2nd International Conference on Smart Grids and Energy Systems, SGES 2023

作者： Jiang, Zhihong Liu, Guiyuan Song, Kangnan Li, Han Yang, Hao Wu, Han Changchun Institute of Technology School of Electrical Engineering and Information Technology Changchun China National Local Joint Engineering Research Center for Smart Distribution Grid Measurement and Control With Safety Operation Technology Changchun China International Joint Research Center for New Energy Power Generation and Network Control Technology of Jilin Province Changchun China

ISBN: (纸本)9798350371659

Under the high penetration rate of wind power, the power system puts forward technical requirements for the frequency regulation capability of wind farms. Considering that the frequency response capability of the double-fed induction generator (DFIG) is insufficient, it is proposed to combine energy storage (ES) with wind power for system frequency regulation. Based on the frequency characteristic models of the wind farm and the ES system, this paper establishes a prediction model for the over speed control of the wind farm and a prediction model for the electrochemical energy storage system, and optimizes the active power output of the wind turbine and the energy storage system. The strategy is based on the optimal control of the wind turbine output power and ES power variation, and on this basis, an optimal control model considering the ES state of charge (SOC) and power is designed. The simulation results show that the proposed control strategy can not only effectively suppress grid frequency deviation can also coordinate the ES state of charge and frequency control. © 2023 IEEE.

关键词： Model predictive control

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The development of high-strength flame-retardant magnesium alloys

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Journal of Materials research and Technology 2025年 36卷 5797-5823页

作者： Xian-Wen Chen Hong-Yu Yang Bai-Xin Dong Tian-Shu Liu Lin Liu Zheng Tian Lei Zhan Cheng-Gang Wang Zhi-Gang Li Jia Meng Jian Qiao Wei-Dong Yang Ming Zhu Shi-Li Shu Feng Qiu Qi-Chuan Jiang State Key Laboratory of Automotive Simulation and Control Jilin University PR China Key Laboratory of Automobile Materials Ministry of Education and Department of Materials Science and Engineering Jilin University Renmin Street NO. 5988 Changchun Jilin Province 130025 PR China Jilin Jiyan New Materials Technology Co. Ltd No. 21 Ecological East Street Jingyue High tech Zone Changchun 130119 PR China School of Engineering Changchun Normal University Changchun 130032 PR China School of Automotive Engineering Jilin Communication Polytechnic Changchun 130012 PR China Technology Research and Development Casting & Forging Research Institute FAW Foundry Co. Ltd Crossing of Hexie Street & Bingwu Road Automotive Industry Development Zone Changchun Jilin Province 130013 PR China Department and Test Center FAW-Volkswagen Automotive Co. Ltd Changchun Jilin Province 130011 PR China School of Mechatronic Engineering and Automation Foshan University No. 33 Guangyun Road Nanhai District Foshan Guangdong Province 528231 PR China Jilin Liyuan Precision manufacturing Co. Ltd. No. 5729 Xi'ning Road Economic Development Zone LiaoYuan Jilin Province 136299 PR China Zhenjiang Xianfeng Automotive Parts Co. Ltd Dantu High tech Industrial Park Zhenjiang Jiangsu Province 212000 PR China School of Mechanical and Aerospace Engineering Jilin University Renmin Street NO. 5988 Changchun 130025 PR China

Magnesium alloys possess a great potential for applications in the automobile and aerospace industries due to their extremely low density, exceptional machinability and enhanced dampening capacity. However, the low elastic modulus, low ductility, high flammability, and susceptibility to corrosion dramatically impeded their applications. In recent decades, some progress has been made in reinforcing magnesium alloys by alloying elements and nanoparticles to achieve higher strength and ignition points. The low melting point and low strength of magnesium alloy are their most significant drawback. The Federal Aviation Administration (FAA) of the United States lifts the ban on the use of magnesium alloys in aircraft cabins after evaluating some non-flammable magnesium alloys considering the advancement of flame-retardant magnesium alloys. Developing high flame-retardant magnesium alloys with good mechanical properties has broad prospects. The aim of this study was to comparatively review the effects of alloying elements and nanoparticles on the strength and flame retardancy of magnesium alloys and reveal the strengthening mechanism of flame retardancy. This article can offer a guideline for the compositional design of high-performance flame-retardant magnesium alloys.

关键词： Flame-retardant Ignite Alloying Nanoparticle Microstructure Influence mechanisms

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Bifunctional passivation by lewis-base molecules for efficient printable mesoscopic perovskite solar cells

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Journal of Energy Chemistry 2024年第9期96卷 177-184页

作者： Hang Yang Jianhong Zhao Xiaodong Ren Tong Zhou Henbing Zhang Weilong Zhang Jin Zhang Guangzhi Hu Yuming Zhang Wen-Hua Zhang Qingju Liu Yunnan Key Laboratory for Micro/Nano Materials & Technology National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan UniversityKunming 650091YunnanChina Institute for Ecological Research and Pollution Control of Plateau Lakes School of Ecology and Environmental Science Yunnan UniversityKunming 650091YunnanChina

Printable mesoscopic perovskite solar cells(PM-PSCs)possess notable merits in terms of cost-effectiveness,easy manufacturing,and large scale ***,the absence of a hole transport layer contributes to the exacerbation of carrier recombination,and the defects between the perovskite and electron transport layer(ETL)interfaces significantly decrease the efficiency of the *** this study,a bifunctional surface passivation approach is proposed by applying a thioacetamide(TAA)surfactant on the mesoporous TiO_(2)*** results demonstrate that TAA molecules could interact with TiO_(2),thereby diminishing the oxygen vacancy ***,the amino group and sulfur atoms in TAA molecules act as Lewis base to effectively passivate the uncoordinated Pb^(2+)in perovskite and improve the morphology of perovskite,and decrease the trap-state density of *** TAA passivation mechanism improves the alignment of energy levels between TiO_(2)and perovskite,facilitating electron transport and reducing carrier ***,the TAA-passivated device achieved a champion power conversion efficiency(PCE)of 17.86%with a high fill factor(FF)of 79.16%and an open-circuit voltage(V_(OC))of 0.971 *** investigation presents a feasible strategy for interfacial passivation of the ETL to further improve the efficiency of PM-PSCs.

关键词： Perovskite solarcells Carbon electrode Thioacetamide Interfacial passivation

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Direct Probe of Spectrally Line-Narrowed Emission from Cooperative Optical State in p-conjugated Polymer Films

Direct Probe of Spectrally Line-Narrowed Emission from Coope...

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International Conference on Ultrafast Phenomena, UP 2000

作者： Jeoung, Sae Chae Kim, Dongho National Creative Research Initiatives Center for Ultrafast Optical Characteristics Control and Spectroscopy Laboratory Korea Research Institute of Standards and Science Taejon305-600 Korea Republic of

New results of time-resolved emission spectroscopy of rc-conjugated polymeric thin film revealed an apparent induction time for the appearance of spectrally narrowed emission (SNE) in contrast with an instantaneous bu... 详细信息

ISBN: (纸本)1557526400

关键词： Emission spectroscopy

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Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation Underlie Silver Nanoparticles-Induced Neurologic Deficits in Adult Mice

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Journal of biochemical and molecular toxicology 2025年第6期39卷 e70289页

作者： Wenhui Zhang Mengdi Zhai Meijia Wu Yongke Yuan Xiao Su Mingzhi Yang Yue Ba Qihong Deng Yu Zhang Lin Han Lihua Gao Hui Huang Department of Environmental Health College of Public Health Zhengzhou University Zhengzhou Henan province China. State Key Laboratory of Microbial Technology Qingdao Shandong China. Shandong Engineering Research Center of Biomarker and Artificial Intelligence Application Jinan Shandong China. Institute of Marine Science and Technology Shandong University Qingdao Shandong China. Zhengzhou Center for Disease Control and Prevention Zhengzhou Henan China.

Silver nanoparticles (AgNPs) are extensively mass-produced and widely utilized across diverse fields owing to their potent bactericidal properties. Nevertheless, prior research regarding the distribution of AgNPs In Vivo has revealed that they can penetrate into and accumulate in brain tissue, potentially leading to neurotoxicity. In the current study, we initially delved into the impacts of different dosages of AgNPs (10-250 mg/kg body weight) on behavioral cognitive function. After 28 days of oral ingestion of AgNPs, we observed impaired learning and memory performance in the high-dose-treated group of mice. Moreover, we evaluated the alterations in molecules associated with endoplasmic reticulum (ER) stress and the activation of the NOD-like receptor protein 3 (NLRP3) inflammasome, conducting a preliminary exploration of the neurotoxic mechanisms of AgNPs. The results demonstrated that subacute oral exposure to AgNPs might disrupt cognitive function via the ER stress and NLRP3 inflammasome activation pathways. Our data highlight the neurotoxic effects of AgNPs and the significant role played by NLRP3 inflammasome activation in neurological deficits.

关键词： NOD‐like receptor protein 3 inflammasome neurological lesion pro‐inflammatory cascade silver nanoparticles unfolded protein response

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research on monopulse forward-looking high-resolution imaging algorithm based on adaptive iteration

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Defence Technology（防务技术） 2020年第1期16卷 158-171页

作者： Cheng Cheng Xiao-dong Zhou Min Gao Zhu-lin Zong Yong-xiang Ji Bo Yu Department of Missile Engineering Army Engineering UniversityNo.97 Westroad HepingShijiazhuangChina Department of Ammunition Engineering Army Engineering UniversityNo.97 Westroad HepingShijiazhuangChina Research Institute of Electronic Science and Technology University of Electronic Science and TechnologyNo.4Section 2Jianbei RoadChengduChina China Huayin Weapon Test Center No.450 Yuemiao StreetHuayinShaanxiChina North Automatic Control Technology Institute No.351 Tiyu RoadTaiyuanChina

In this paper,we proposed a monopulse forward-looking high-resolution imaging algorithm based on adaptive iteration for missile-borne *** iteration,the proposed algorithm automatically selects the echo signal of isolated strong-scattering points from the receiving echo signal data to accurately estimate the actual optimal monopulse response curve(MRC) of the same distance range,and we applied optimal MRC to realize the azimuth self-focusing in the process of *** use real-time echo data to perform error correction for obtaining the optimal MRC,and the azimuth angulation accuracy may reach the optimum at a certain distance *** experimentally demonstrate the validity,reliability and high performance of the proposed *** azimuth angulation accuracy may reach up to ten times of the detection *** simulation experiments have verified the feasibility of this strategy,with the average height measurement error being 7.8%.In the out-field unmanned aerial vehicle(UAV) tests,the height measurement error is less than 25 m,and the whole response time can satisfy the requirements of a missile-borne detector.

关键词： Monopulse imaging High-resolution Adaptive iteration Missile-borne detector

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