Event ontology is a new biomedical ontology developed to annotate pathway components in a pathway database It organizes the concepts and terms of sub-pathways, pathways, biological phenomena, experimental conditions, ...
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ISBN:
(纸本)9812564632
Event ontology is a new biomedical ontology developed to annotate pathway components in a pathway database It organizes the concepts and terms of sub-pathways, pathways, biological phenomena, experimental conditions, medications, and external stimuli appearing in biological pathways (e.g. signal transduction, disease-, metabolic-, molecular interaction-, genetic interaction pathways, etc.). Concepts in the Event ontology are extracted manually from scientific literature. Each term has links to external databases such as Gene Ontology, Reactome, KEGG, BioCyc, and PubMed.
High-throughput proteome annotation refers to the activity of extracting information from all proteins in a particular organism using bioinformatics software on a high performance computing platform such as the grid. ...
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We perform first-principles calculations of the conductance of Al and Si atomic wires between jellium electrodes using the wave-function matching method combined with the density-functional theory. The calculated cond...
We perform first-principles calculations of the conductance of Al and Si atomic wires between jellium electrodes using the wave-function matching method combined with the density-functional theory. The calculated conductances for single-line and double-line atomic wires exhibit rich variation depending on the detailed atomic structure and the chemical difference between the constituent elements. The origin of the similarity and dissimilarity between Al and Si atomic wires is unequivocally clarified by our eigenchannel analyses of the wave functions and transmission probabilities obtained and by the calculated energy bands of the corresponding infinite-length atomic wires. We also find that the conductance of single-line Al wires increases upon stretching of the wires. This is due to peculiar features of the electron states of atomic wires consisting of group III or group IV atoms. The result is consistent with the observed conductance of Al wires.
The dispersion relation and the optical transmittance of a two-dimensional photonic crystal composed of the hexagonal array of cylindrical air holes fabricated in a dielectric slab were analyzed by group theory and th...
The dispersion relation and the optical transmittance of a two-dimensional photonic crystal composed of the hexagonal array of cylindrical air holes fabricated in a dielectric slab were analyzed by group theory and the numerical calculation based on the finite-difference time-domain method. The decay rate of the leaky modes that exist above the light line (the dispersion relation in air) in the band diagram was also evaluated, from which the absence of the coupling between certain internal eigenmodes and the external radiation field was shown. This phenomenon was related to symmetry mismatching by the group-theoretical argument. It was also shown that a certain leaky band has a quality factor as large as 3000 over its entire spectral range. These features as well as the opaque frequency regions due to symmetry mismatching were clearly demonstrated by the calculated optical transmission spectra.
Reduced manning is the process (and the result) of removing human functions from a system while retaining or improving system operability and effectiveness. Reliability and maintainability characterize a system's ...
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Reduced manning is the process (and the result) of removing human functions from a system while retaining or improving system operability and effectiveness. Reliability and maintainability characterize a system's operability and effectiveness. Reduced manning impacts system reliability by changing the characteristics of (1) human error associated with system operation and maintenance, (2) time to repair failed components, and (3) mean-time-between-failures (MBTF) in a reduced manning environment. Simply reducing manning without compensating for system dependence on human involvement generally has a negative impact on system maintainability. Methods to address this include (1) human-system integration design of maintenance interfaces and (2) design of operations activities that are closely related to device failures. After demonstrating reliable performance through testing and operation, ship commanders can be assured that fewer people can effectively operate and maintain Navy ships and systems.
Providing realistic opposing forces is critical to the successful use of military training simulations. Unfortunately, a number of issues can make the manual control of realistic opposing forces difficult or unattaina...
Providing realistic opposing forces is critical to the successful use of military training simulations. Unfortunately, a number of issues can make the manual control of realistic opposing forces difficult or unattainable, This paper explores these issues while discussing how Automatic Interactive Targets (AITs) can assist Training Exercise Controllers (TECs) in providing validated and realistic opposing forces in highly interactive situations. The features of the prototype Remote AIT Processing System (RAPS) are used to demonstrate how an AIT system can be designed to meet TEC requirements for automated entities, RAPS can provide remote control of AITs for existing or new systems while providing sufficient features to allow a TEC to appropriately select and control AITs for individual training exercises and crew proficiencies.
作者:
ZITZMAN, LHFALATKO, SMPAPACH, JLDr. Lewis H. Zitzman:is the group supervisor of the Advanced Systems Design Group
Fleet Systems Department The Johns Hopkins University Applied Physics Laboratory (JHU/APL). He has been employed at JHU/APL since 1972 performing applied research in computer science and in investigating and applying advanced computer technologies to Navy shipboard systems. He is currently chairman of Aegis Computer Architecture Data Bus and Fiber Optics Working Group from which many concepts for this paper were generated. Dr. Zitzman received his B.S. degree in physics from Brigham Young University in 1963 and his M.S. and Ph.D. degrees in physics from the University of Illinois in 1967 and 1972 respectively. Stephen M. Falatko:was a senior engineering analyst in the Combat Systems Engineering Department
Comptek Research Incorporated for the majority of this effort. He is currently employed at ManTech Services Corporation. During his eight-year career first at The Johns Hopkins University Applied Physics Laboratory and currently with ManTech Mr. Falatko's work has centered around the development of requirements and specifications for future Navy systems and the application of advanced technology to Navy command and control systems. He is a member of both the Computer Architecture Fiber Optics and Data Bus Working Group and the Aegis Fiber Optics Working Group. Mr. Falatko received his B.S. degree in aerospace engineering with high distinction from the University of Virginia in 1982 and his M.S. degree in applied physics from The Johns Hopkins University in 1985. Mr. Falatko is a member of Tau Beta Pi Sigma Gamma Tau the American Society of Naval Engineers and the U.S. Naval Institute. Janet L. Papach:is a section leader and senior engineering analyst in the Combat Systems Engineering Department
Comptek Research Incorporated. She has ten years' experience as an analyst supporting NavSea Spa War and the U.S. Department of State. She currently participates in working group efforts under Aegis Combat System Doctrin
This paper sets forth computer systems architecture concepts for the combat system of the 2010–2030 timeframe that satisfy the needs of the next generation of surface combatants. It builds upon the current Aegis comp...
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This paper sets forth computer systems architecture concepts for the combat system of the 2010–2030 timeframe that satisfy the needs of the next generation of surface combatants. It builds upon the current Aegis computer systems architecture, expanding that architecture while preserving, and adhering to, the Aegis fundamental principle of thorough systems engineering, dedicated to maintaining a well integrated, highly reliable, and easily operable combat system. The implementation of these proposed computer systems concepts in a coherent architecture would support the future battle force capable combat system and allow the expansion necessary to accommodate evolutionary changes in both the threat environment and the technology then available to effectively counter that threat. Changes to the current Aegis computer architecture must be carefully and effectively managed such that the fleet will retain its combat readiness capability at all times. This paper describes a possible transition approach for evolving the current Aegis computer architecture to a general architecture for the future. The proposed computer systems architecture concepts encompass the use of combinations of physically distributed, microprocessor-based computers, collocated with the equipment they support or embedded within the equipment itself. They draw heavily on widely used and available industry standards, including instruction set architectures (ISAs), backplane busses, microprocessors, computer programming languages and development environments, and local area networks (LANs). In this proposal, LANs, based on fiber optics, will provide the interconnection to support system expandability, redundancy, and higher data throughput rates. A system of cross connected LANs will support a high level of combat system integration, spanning the major warfare areas, and will facilitate the coordination and development of a coherent multi-warfare tactical picture supporting the future combatant command st
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