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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Steven... 详细信息

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

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Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: the Global Burden of Diseases Study 2019

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The Lancet HIV 2021年第10期8卷 e633-e651页

作者： Jahagirdar, Deepa Walters, Magdalene K. Novotney, Amanda Brewer, Edmond D. Frank, Tahvi D. Carter, Austin Biehl, Molly H. Abbastabar, Hedayat Abhilash, E.S. Abu-Gharbieh, Eman Abu-Raddad, Laith Jamal Adekanmbi, Victor Adeyinka, Daniel Adedayo Adnani, Qorinah Estiningtyas Sakilah Afzal, Saira Aghababaei, Soodabeh Ahinkorah, Bright Opoku Ahmad, Sajjad Ahmadi, Keivan Ahmadi, Sepideh Ahmadpour, Ehsan Ahmed, Muktar Beshir Rashid, Tarik Ahmed Salih, Yusra Ahmed Aklilu, Addis Akram, Tayyaba Akunna, Chisom Joyqueenet Al Hamad, Hanadi Alahdab, Fares Alanezi, Fahad Mashhour Aleksandrova, Ekaterina A. Alene, Kefyalew Addis Ali, Liaqat Alipour, Vahid Almustanyir, Sami Alvis-Guzman, Nelson Ameyaw, Edward Kwabena Amu, Hubert Andrei, Catalina Liliana Andrei, Tudorel Anvari, Davood Arabloo, Jalal Aremu, Olatunde Arulappan, Judie Atnafu, Desta Debalkie Quintanilla, Beatriz Paulina Ayala Ayza, Muluken Altaye Azari, Samad Darshan, B.B. Banach, Maciej Bärnighausen, Till Winfried Barra, Fabio Barrow, Amadou Basu, Sanjay Bazargan-Hejazi, Shahrzad Belay, Habtamu Gebrehana Berheto, Tezera Moshago Bezabhe, Woldesellassie Mequanint Bezabih, Yihienew Mequanint Bhagavathula, Akshaya Srikanth Bhardwaj, Nikha Bhardwaj, Pankaj Bhattacharyya, Krittika Bibi, Sadia Bijani, Ali Bisignano, Catherine Bolarinwa, Obasanjo Afolabi Boloor, Archith Boltaev, Azizbek A. Briko, Nikolay Ivanovich Buonsenso, Danilo Burkart, Katrin Butt, Zahid A. Cao, Chao Charan, Jaykaran Chatterjee, Souranshu Chattu, Soosanna Kumary Chattu, Vijay Kumar Choudhari, Sonali Gajanan Chu, Dinh-Toi Couto, Rosa A.S. Cowden, Richard G. Dachew, Berihun Assefa Dadras, Omid Dagnew, Amare Belachew Dahlawi, Saad M.A. Dai, Xiaochen Dandona, Lalit Dandona, Rakhi das Neves, José Degenhardt, Louisa Demeke, Feleke Mekonnen Desta, Abebaw Alemayehu Deuba, Keshab Dhamnetiya, Deepak Dhungana, Govinda Prasad Dianatinasab, Mostafa Diaz, Daniel Djalalinia, Shirin Doan, Linh Phuong Dorostkar, Fariba Edinur, Hisham Atan Effiong, Andem Eftekharzadeh, Sahar El Sayed Zaki, Maysaa Elayedath, Rajesh Elhadi, Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Division of Allergy and Infectious Diseases University of Washington Seattle WA United States Department of Global Health University of Washington Seattle WA United States School of Social Work University of Washington Seattle WA United States Department of Medicine University of Washington Seattle WA United States Vagelos College of Physicians and Surgeones Columbia University Medical Center New York NY United States Division of Data Analytics and Delivery for Impact WHO Geneva Switzerland Advanced Diagnostic and Interventional Radiology Research Centre Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Centre Tehran University of Medical Sciences Tehran Iran School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Paediatric Chronic Kidney Disease Research Centre Tehran University of Medical Sciences Tehran Iran Department of Psychiatry Tehran University of Medical Sciences Tehran Iran Metabolomics and Genomics Research Centre Tehran University of Medical Sciences Tehran Iran Sina Trauma and Surgery Research Centre Tehran University of Medical Sciences Tehran Iran Research Centre for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Non-Communicable Diseases Research Centre Tehran University of Medical Sciences Tehran Iran Department of Botany Sree Narayana Guru College Chelannur Kozhikode India Clinical Sciences Department University of Sharjah Sharjah United Arab Emirates Mass Communication Department University of Sharjah Sharjah United Arab Emirates Department of Health-Care Policy and Research Weill Cornell Medical College in Qatar Doha Qatar Department of Population Medicine Ca

Background: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. Thi...

Background: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. Methods: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). Findings: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1–38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78–0·91) per female living with HIV in 2019, 0·99 male infections (0·91–1·10) for every female infection, and 1·02 male deaths (0·95–1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58–35·43, and a 39·66% decrease in deaths, 36·49–42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05–0·06) and the global incidence-to-mortality ratio was

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Corrigendum: A review of trends and drivers of greenhouse gas emissions by sector from 1990 to 2018 (2021 Environ. Res. Lett. 16 073005)

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Environmental research Letters 2022年第4期17卷 049502-049502页

作者： William F Lamb Thomas Wiedmann Julia Pongratz Robbie Andrew Monica Crippa Jos G J Olivier Dominik Wiedenhofer Giulio Mattioli Alaa Al Khourdajie Jo House Shonali Pachauri Maria Figueroa Yamina Saheb Raphael Slade Klaus Hubacek Laixiang Sun Suzana Kahn Ribeiro Smail Khennas Stephane de la Rue du Can Lazarus Chapungu Steven J Davis Igor Bashmakov Hancheng Dai Shobhakar Dhakal Xianchun Tan Yong Geng Baihe Gu Jan Minx Mercator Research Institute on Global Commons and Climate Change Torgauer Straße 12–15 4 EUREF Campus #19 10829 Berlin Germany School of Earth and Environment University of Leeds LS2 9JT Leeds United Kingdom Sustainability Assessment Program School of Civil and Environmental Engineering UNSW Sydney Sydney Australia Max Planck Institute for Meteorology Bundesstrasse 53 20146 Hamburg Germany Department of Geography Ludwig-Maximilians-Universität Munich Luisenstrasse 37 80333 Munich Germany CICERO Center for International Climate Research Oslo Norway European Commission Joint Research Centre Ispra VA Italy PBL Netherlands Environmental Assessment Agency Den Haag The Netherlands Institute of Social Ecology University of Natural Resources and Life Sciences Schottenfeldgasse 29 1070 Vienna Austria Department of Transport Planning TU Dortmund University August-Schmidt-Straße 10 44227 Dortmund Germany Centre for Environmental Policy Imperial College London London United Kingdom School of Geographical Sciences University of Bristol University Road BS8 1SS Bristol United Kingdom International Institute for Applied Systems Analysis (IIASA) Schlossplatz 1 2361 Laxenburg Austria Department of Management Society and Communication Copenhagen Business School Copenhagen Denmark Openexp 17 Bd Lefebvre 75015 Paris France Integrated Research for Energy Environment and Society University of Groningen 9747AG Groningen The Netherlands Department of Geographical Sciences University of Maryland College Park MD 20742 United States of America School of Finance and Management SOAS University of London WC1H 0XG London United Kingdom Institute of Blue and Green Development Weihai Institute of Interdisciplinary Research Shandong University Weihai 264209 People’s Republic of China Federal University of Rio de Janeiro (Universidade Federal do Rio de Janeiro—UFRJ) Transport Engineering Programme (Programa de Engenharia de Transportes—PET) COPPE-UFRJ Rio de Janeiro Brazil Energy

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Harmonization of tau-PET in Alzheimer’s disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK-6240

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Alzheimer's & Dementia 2023年第S14期19卷

作者： Antoine Leuzy Vincent Dore Lars Lau Raket Gregory Klein Suzanne L. Baker Maria C. Carrillo Arnaud Charil Emily C. Collins Jessica A. Collins Samantha Budd Haeberlein Makoto Higuchi Eric D. Hostetler R. Matthew Hutchison Leonardo Iaccarino Michael C. Irizarry William J. Jagust Keith A. Johnson Yashmin Karten Hartmuth C. Kolb Brian J. Lopresti Sulantha Mathotaarachchi Mark A. Mintun Rik Ossenkoppele Ioannis Pappas Tharick A. Pascoal Michael J. Pontecorvo Gil D. Rabinovici Pedro Rosa-Neto Ziad S. Saad Sandra Sanabria Bohorquez Andrew W. Stephens Sudhir Sivakumaran Matteo Tonietto Ruben Smith Christopher C Rowe Victor L Villemagne Oskar Hansson Clinical Memory Research Unit Lund University Lund Sweden Critical Path for Alzheimer’s Disease (CPAD) Consortium Critical Path institute Tucson AZ USA Cerveau Technologies Inc. Knoxville TN USA Correspondece Health and Biosecurity Flagship The Australian eHealth Research Centre CSIRO Victoria Australia Austin Health Victoria Australia Novo Nordisk A/S Søborg Denmark F. Hoffmann-La Roche Ltd Basel Switzerland Lawrence Berkeley National Laboratory Berkeley CA USA Alzheimer’s Association Chicago IL USA Eisai Inc. Nutley NJ USA Avid Radiopharmaceuticals Philadelphia PA USA Eli Lilly and Company Indianapolis IN USA Biogen Cambridge MA USA National Institutes for Quantum Science and Technology Chiba Japan Merck & Co. Inc. West Point PA USA University of California Berkeley Berkeley CA USA Harvard Medical School Boston MA USA Gordon Center for Medical Imaging Boston MA USA Neuroscience Biomarkers Janssen Research and Development LLC San Diego CA USA University of Pittsburgh Pittsburgh PA USA Alzheimer Center Amsterdam Neurology Vrije Universiteit Amsterdam Amsterdam UMC location VUmc Amsterdam Netherlands Amsterdam Neuroscience Neurodegeneration Amsterdam Netherlands Helen Wills Neuroscience Institute University of California Berkeley CA USA VA Northern California Health Care System Martinez CA USA University of Pittsburgh School of Medicine Pittsburgh PA USA Memory and Aging Center Weill Institute for Neurosciences University of California San Francisco San Francisco CA USA Translational Neuroimaging Laboratory Montreal QC Canada Montreal Neurological Institute McGill University Montreal QC Canada Genentech Inc. South San Francisco CA USA Life Molecular Imaging GmbH Berlin Germany Neurology Clinic Skåne University Hospital Lund Sweden The Australian Dementia Network (ADNeT) Melbourne VIC Australia The University of Melbourne Parkville VIC Australia Memory Clinic Skåne University Hospital Malmö Sweden

Background Tau positron emission tomography (PET) is increasingly used in the clinical evaluation of patients and as an outcome measure in Alzheimer’s disease (AD) clinical trials. Due to differences in tracer proper...

Background Tau positron emission tomography (PET) is increasingly used in the clinical evaluation of patients and as an outcome measure in Alzheimer’s disease (AD) clinical trials. Due to differences in tracer properties, instrumentation, and methods of analysis, however, tau-PET outcome data cannot currently be meaningfully compared or combined. Here, we tested i) the feasibility of adapting the Centiloid method—an approach originally developed to standardize amyloid PET—to harmonize tau-PET quantification (CenTauRs); ii) the performance of a non-linear mixed model-based approach (Joint Propagation Model) that does not require the use of a reference tracer. Methods Head-to-head tau-PET data (Table 1) was included from two cohorts ([ 18 F]RO948 vs [ 18 F]flortaucipir, n = 37 [BioFINDER-2]; [ 18 F]flortaucipir [Avid A05] vs [ 18 F]MK-6240, n = 15, University of Pittsburgh) in which each participant was scanned with two tau-PET tracers. Standardized uptake value ratio (SUVR) values were calculated using the inferior cerebellar cortex as the reference region. Anchor point data (Table 1) was derived for each tracer using the following criteria: CenTauR-0, cognitively unimpaired (CU), amyloid PET negative (<10 Centiloids); CenTauR-100, amyloid PET positive (>50 Centiloids), typical (temporoparietal) AD pattern on tau-PET visual read, age<65 andMMSE>20. Regions-of-interest (ROIs) included a universal tau-PET ROI—based on the intersection of tracer specific ([ 18 F]flortaucipir, [ 18 F]MK-6240, [ 18 F]PI-2620, [ 18 F]PM-PBB3, [ 18 F]GTP1 and [ 18 F]RO948) masks that had been derived by subtracting average of amyloid-negative CU images from the average AD image—as well as four subregions delineated within this ROI (medial temporal, meta-temporal, temporoparietal and frontal) (Figure 1A). An overview of the adapted Centiloid-like approach and the joint propagation model is shown in Figure 1B. Results High R 2 values were observed between tracers across all ROIs: [ 18 F]RO948

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Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism

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Nature communications 2023年第1期14卷 7752页

作者： Maria Jesus Iglesias Laura Sanchez-Rivera Manal Ibrahim-Kosta Clément Naudin Gaëlle Munsch Louisa Goumidi Maria Farm Philip M Smith Florian Thibord Julia Barbara Kral-Pointner Mun-Gwan Hong Pierre Suchon Marine Germain Waltraud Schrottmaier Philip Dusart Anne Boland David Kotol Fredrik Edfors Mine Koprulu Maik Pietzner Claudia Langenberg Scott M Damrauer Andrew D Johnson Derek M Klarin Nicholas L Smith David M Smadja Margareta Holmström Maria Magnusson Angela Silveira Mathias Uhlén Thomas Renné Angel Martinez-Perez Joseph Emmerich Jean-Francois Deleuze Jovan Antovic Jose Manuel Soria Fernandez Alice Assinger Jochen M Schwenk Joan Carles Souto Andres Pierre-Emmanuel Morange Lynn Marie Butler David-Alexandre Trégouët Jacob Odeberg Science for Life Laboratory Department of Protein Science CBH KTH Royal Institute of Technology SE-171 21 Stockholm Sweden. Division of Internal Medicine University Hospital of North Norway (UNN) PB100 9038 Tromsø Norway. Translational Vascular Research Department of Clinical Medicine UiT The Arctic University of Norway 9019 Tromsø Norway. Aix-Marseille Univ INSERM INRAE C2VN Laboratory of Haematology CRB Assistance Publique-Hôpitaux de Marseille HemoVasc (CRB AP-HM HemoVasc) Marseille France. University of Bordeaux INSERM Bordeaux Population Health Research Center UMR 1219 ELEANOR Bordeaux France. Department of Molecular Medicine and Surgery Karolinska Institute Stockholm Sweden. Department of Clinical Chemistry Karolinska University Hospital Stockholm Sweden. Department of Medicine Solna Karolinska Institute and Karolinska University Hospital Stockholm Sweden. Theme of Emergency and Reparative Medicine Karolinska University Hospital Stockholm Sweden. Population Sciences Branch Division of Intramural Research National Heart Lung and Blood Institute Framingham MA USA. The Framingham Heart Study Boston University Framingham MA USA. Center for Physiology and Pharmacology Institute of Vascular Biology and Thrombosis Research Medical University of Vienna Vienna Austria. Laboratory of Excellence GENMED (Medical Genomics) Bordeaux France. Université Paris-Saclay CEA Centre National de Recherche en Génomique Humaine (CNRGH) 91057 Evry France. Laboratory of Excellence GENMED (Medical Genomics) Evry France. MRC Epidemiology Unit University of Cambridge School of Clinical Medicine Institute of Metabolic Science Cambridge CB2 0QQ UK. Computational Medicine Berlin Institute of Health at Charité-Universitätsmedizin Berlin 10117 Berlin Germany. Precision Healthcare University Research Institute Queen Mary University of London London UK. Corporal Michael Crescenz VA Medical Center Philadelphia PA USA. Department of Surgery and Department of Genetics

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Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

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Genome biology 2024年第1期25卷 129页

作者： Jonathan P Bradfeld Rachel L Kember Anna Ulrich Zhanna Balkhiyarova Akram Alyass Izzuddin M Aris Joshua A Bell K Alaine Broadaway Zhanghua Chen Jin-Fang Chai Neil M Davies Dietmar Fernandez-Orth Mariona Bustamante Ruby Fore Amitavo Ganguli Anni Heiskala Jouke-Jan Hottenga Carmen Íñiguez Sayuko Kobes Jaakko Leinonen Estelle Lowry Leo-Pekka Lyytikainen Anubha Mahajan Niina Pitkänen Theresia M Schnurr Christian Theil Have David P Strachan Elisabeth Thiering Suzanne Vogelezang Kaitlin H Wade Carol A Wang Andrew Wong Louise Aas Holm Alessandra Chesi Catherine Choong Miguel Cruz Paul Elliott Steve Franks Christine Frithiof-Bøjsøe W James Gauderman Joseph T Glessner Vicente Gilsanz Kendra Griesman Robert L Hanson Marika Kaakinen Heidi Kalkwarf Andrea Kelly Joseph Kindler Mika Kähönen Carla Lanca Joan Lappe Nanette R Lee Shana McCormack Frank D Mentch Jonathan A Mitchell Nina Mononen Harri Niinikoski Emily Oken Katja Pahkala Xueling Sim Yik-Ying Teo Leslie J Baier Toos van Beijsterveldt Linda S Adair Dorret I Boomsma Eco de Geus Mònica Guxens Johan G Eriksson Janine F Felix Frank D Gilliland Torben Hansen Rebecca Hardy Marie-France Hivert Jens-Christian Holm Vincent W V Jaddoe Marjo-Riitta Järvelin Terho Lehtimäki David A Mackey David Meyre Karen L Mohlke Juha Mykkänen Sharon Oberfeld Craig E Pennell John R B Perry Olli Raitakari Fernando Rivadeneira Seang-Mei Saw Sylvain Sebert John A Shepherd Marie Standl Thorkild I A Sørensen Nicholas J Timpson Maties Torrent Gonneke Willemsen Elina Hypponen Chris Power Mark I McCarthy Rachel M Freathy Elisabeth Widén Hakon Hakonarson Inga Prokopenko Benjamin F Voight Babette S Zemel Struan F A Grant Diana L Cousminer Center for Applied Genomics Children's Hospital of Philadelphia Philadelphia PA 19104 USA. Center for Spatial and Functional Genomics Children's Hospital of Philadelphia Philadelphia PA 19104 USA. Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia USA. Department of Clinical & Experimental Medicine University of Surrey Guildford UK. Department of Metabolism Digestion and Reproduction Imperial College London London UK. People-Centred Artifcial Intelligence Institute University of Surrey Guildford UK. Department of Health Research Methods Evidence and Impact McMaster University Hamilton Canada. Division of Chronic Disease Research Across the Lifecourse Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute Boston MA 02215 USA. MRC Integrative Epidemiology Unit at the University of Bristol Bristol UK. Department of Genetics University of North Carolina Chapel Hill NC USA. Department of Population and Public Health Sciences University of Southern California Los Angeles CA 90032 USA. Saw Swee Hock School of Public Health National University of Singapore and National University Health System Singapore Singapore. Bristol Medical School Population Health Sciences University of Bristol Bristol UK. K.G. Jebsen Center for Genetic Epidemiology Department of Public Health and Nursing NTNU Norwegian University of Science and Technology Trondheim Norway. ISGlobal Barcelona Spain. Center for Life Course Health Research University of Oulu Oulu Finland. Department of Biological Psychology Vrije Universiteit Amsterdam Amsterdam The Netherlands. Department of Statistics and Computational Research Universitat de València Valencia Spain. CIBER Epidemiología y Salud Pública (CIBERESP) Madrid Spain. Epidemiology and Environmental Health Joint Research Unit FISABIO-Universitat Jaume I-Universitat de València Valencia Spain. Phoenix Epidemiology and Clinical Research Center NIDDK

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40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

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Diabetologia 2004年第SUPPL 1期47卷 A1-A464页

作者： Veitenhansl, M. Stegner, K. Hierl, F.-X. Dieterle, C. Feldmeier, H. Gutt, B. Landgraf, R. Garrow, A. P. Vileikyte, L. Findlow, A. Waterman, C. Boulton, A. J. M. Shankhdhar, K. Shankhdhar, L. Shankhdhar, U. Petrova, N. L. Foster, A. V. M. Edmonds, M. E. Ferraresi, R. Caravaggi, C. De Giglio, R. Cavaiani, P. Pogliaghi, I. Sommariva, E. Katz, I. A. Harlan, A. Miranda-Palma, B. Prieto-Sanchez, L. Armstrong, D. G. Bowker, J. H. Mizel, M. S. Cernea, S. Wohlgelernter, J. Kidron, M. Modi, P. Raz, I. Arbit, E. Nosek, L. Kapitza, C. Beckett, P. Gelfand, R. Goldberg, M. Heise, T. Testa, M. A. Turner, R. R. Hayes, J. F. Scranton, R. E. Simonson, D. C. Yang, Y.-W. Hsu, Y.-J. Naujok, O. Francini, F. Jörns, A. Tiedge, M. Lenzen, S. Abdel-Wahab, Y. H. A. Marenah, L. Orr, D. F. Shaw, C. Flatt, P. R. Chokkalingam, K. Mansell, P. I. Clausen, P. Ekbom, P. Damm, P. Feldt-Rasmussen, U. Nielsen, B. Mathiesen, E. R. Feldt-Rasmussen, B. Dewan, S. Da Silva, N. Ternan, P. Mc Leong, K. S. Wilding, J. P. H. Asatiani, N. Kurashvili, R. Dundua, M. Shelestova, E. Pagava, K. Ramazashvili, M. Hod, M. Smirnov, S. Petersen, J. L. A. Justesen, T. I. Ringholm Nielsen, L. Müller, C. Højlund, K. Wensaas, A. Kase, E. T. Aas, V. Rustan, A. C. Thoresen, G. H. Levin, K. Beck-Nielsen, H. Gaster, M. Im, S.-S. Kang, S.-Y. Kim, S.-Y. Ahn, Y.-H. Lihn, A. S. Schmoll, D. Werner, T. Kienitz, A. Meyer, M. Barthel, A. Ailett, F. Sutherland, C. Walther, R. Grempler, R. Sasson, S. Reich, R. Tenenbaum, T. Alpert, E. Anfossi, G. Russo, I. Traversa, M. Massucco, P. Mattiello, L. Doronzo, G. Trovati, M. Lally, S. Tan, C. Y. Owens, D. Tomkin, G. H. Porchay, I. Péan, F. Bellili, N. Betoulle, D. Balkau, B. Tichet, J. Marre, M. Fumeron, F. Chatellier, G. Alhenc-Gelas, F. Nichols, G. A. Brown, J. B. Hayes, R. P. Bowman, L. Drexel, H. Saely, C. H. Marte, T. Benzer, W. Langer, P. Hoefle, G. Moll, W. Aczel, S. Karagiannis, E. Lübben, G. Urquhart, R. Edwards, G. Bruce, S. Howlett, H. S. C. Cugnardey, N. Turner, K. C. Park, J.-S. Fiedorek, F. T. Avogaro, A. Gallo, A. Pinton, P. Riz Innenstadt Klinikum der Universität München München Germany Diabetes Center Medizinische Klinik München Germany Medicine The University of Manchester Manchester UK Medicine University of Manchester Manchester UK Podiatry The University of Salford Manchester UK Department of Medicine/Division of Endocrinology Diabetes and Metabolism University of Miami Miami USA Department of Medicine Manchester Royal Infirmary Manchester UK Podiatry L.K.Diabetes Centre Lucknow India Diabetology L.K.Diabetes Centre Lucknow India Medical Nutrition L.K.Diabetes Centre Lucknow India Diabetic Foot Clinic King’s College Hospital London UK Haemodinamic Department - Cardiovascular Division Magenta Hospital Milan Italy Center for the Study and Treatment of Diabetic Foot Pathology Abbiategrasso Hospital Milan Italy Center for the Study and Treatment of Diabetic Foot Pathology Abbiategrasso Hospital Abbiategrasso Italy Department of Orthopedics University of Miami Miami USA Department of Surgery Southern Arizona Veterans Affairs Medical Center Tucson USA Surgery Southern Arizona VA Medical Center Tucson USA Podiatric Medicine and Surgery Rosalind Franklin University School of Medicine and Science North Chicago USA Diabetes Department Center of Diabetes Nutrition and Metabolic Disorders Clug-Napoca Romania Diabetes Unit Hadassah University Hospital Jerusalem Israel Diabetes Unit Hadassah Hebrew University Hospital Jerusalem Israel Research Department Generex Biotechnology Corporation Toronto Canada Hadassah Hebrew University Hospital Jerusalem Israel Medical Research Emisphere Technologies Inc. New York USA Profil Institut fuer Stoffwechselforschung GmbH Neuss Germany Profil Institute for Metabolic Research Neuss Germany Management Profil Inst. für Stoffwechselforschung Düsseldorf Germany Institute for Metabolic Research Profil Neuss Germany Biostatistics Harvard School of Public Health Boston USA Clinical Research Phase V Technologies Wellesley Hills US

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Abstracts

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Environmental Management 1977年第1期1卷 67-96页

作者： Frankenfeld, John W. Schulz, Wolfgang McMurty, George J. Petersen, Gary W. May, G. A. Hering, F. S. Schwartz, J. I. Heywood, J. B. Chigier, N. A. Grohse, E. W. Walker, J. D. Colwell, R. R. Petrakis, L. Pergament, H. S. Thorpe, R. D. Schoepf, Richard W. Krzyczkowski, Roman Henneman, Suzanne S. Hudson, Charles L. Putnam, Evelyn S. Thiesen, Donna J. Parks, G. A. McCarty, Perry L. Leckie, J. O. Schrumpf, Barry J. Simonson, G. H. Paine, D. P. Lawrence, R. D. Pyott, W. T. Leh, M. Elders, W. Combs, J. Caplen, T. Harrison, F. L. Wong, K. M. Heft., R. E. Charnell, Robert L. Lehmann, Edward J. Mallon, Lawrence G. Hatfield, Cecile Adams, Gerald H. Johanning, James Talvitie, Antti Noll, Kenneth E. Miller, Terry Smiarowski, Joseph F. Willis, Cleve E. Foster, John H. Schlesinger, Benjamin Daetz, Douglas Lear, Donald U. Smith, Mona F. Hundemann, Audrey S. Crockett, Pernell W. Werner, Kirk G. Carroll, Thomas E. Maase, David L. Genco, Joseph E. Ifeadi, Christopher N. Lowman, F. G. Christensen, S. W. Van Winkle, W. Mattice, J. S. Harrison, Elizabeth A. Barker, James C. Chesness, Jerry L. Smith, Ralph E. Shaheeen, Donald G. Raney, R. Keith Borton, T. Wezernak, C. T. Raney, R. K. Sherwani, Jabbor K. Moreau, David H. Eisenberg, Norman A. Lynch, Cornelius J. Breeding, Roger J. Johnson, J. D. Foster, K. E. Mouat, D. A. Clark, R. Hyden, John William Owen, Wilfred Bayfield, Neil G. Barrow, Graham C. Stolz, Stephanie B. Wienckowski, Louis A. Brown, Betram S. Keyfitz, Nathan Wilson, W. L. Newman, Peter W. G. Bammi, Deepak Bammi, Dalip Goddard, James E. Chisholm, Tony Walsh, Cliff Brennan, Geoffrey Thompson, K. S. Richardson, R. Jensen, Clayton E. Brown, Dail W. Mirabito, John A. Cowing, Thomas G. Binghamton, Suny Siehl, George H. Albrecht, O. W. Alexander, Ariel Barde, Jean -Philippe Darby, William P. McMichael, Francis Clay Dunlap, Robert W. Muckleston, Keith W. Frankenhoff, Charles A. Giulini, Lorenzo T. Wyatt, T. Black, Peter E. Keating, William Thomas Leonard, M. E. Fisher, E. L. Brunelle, M. F. Dickinson, J. E. Pethig, Rudiger Clapham Exxon Research & Engineering Co. Linden Government Research Lab Coast Guard Washington D.C. Department of Transportation Washington D.C. Office For Remote Sensing of Earth Resources. NASA Earth Resources Survey Program Pennsylvania State University Washington D.C. Department of the Navy Washington D.C. Cambridge. Dept. of Mechanical Engineering Massachusetts Inst. of Technology USA Huntsville. School of Graduate Studies and Research Alabama Univ. USA Dept. of Microbiology. Office of Naval Research Maryland Univ. Arlington Research and Development Co. Pittsburgh AeroChem Research Labs. Inc. Princeton Dept. of the Interior Office of Library Services. Bibliographic Series (Final) Washington D.C. Interplan Corp. Santa Barbara Urban Mass Transportation Adm. Washington D.C. Naval Underwater Systems Center Newport Calif. Mercury Project. National Science Found Stanford Univ Washington D.C. Div. of Advanced Environmental Research & Tech. USA Corvallis. NASA Earth Resources Survey Program Oregon State Univ. Washington D.C. Riverside. Inst. of Geophysics and Planetary Physics National Science Foundation California Univ. Washington D.C. Livermore Lawrence Livermore Lab. California Univ. USA Atlantic Oceanographic and Meteorological Labs. National Oceanic and Atmospheric Administration Miami National Technical Information Service Springfield Miami Univ. Coral Gables School of Law National Oceanic and Atmospheric Administration Rockville National Academy of Sciences Office of Sea Grant Washington D. C. School of Law National Oceanic and Atmospheric Administration Office of Sea Grant. Rockville Norman. Dept. of Civil Engineering and Environmental Science. Urban Mass Transportation Administration Oklahoma Univ. Washington D. C. Knoxville.Dept. of Civil Engineering. Federal Highway Administration Tennessee Univ. Washington D. C. Amherst.Water Resources Research Center. Office of Water Research and Technology Massachusetts Univ. Washington D. C. Calif. Dept. of Industria

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Poster abstracts

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Sleep and Biological Rhythms 2016年第1期5卷 A1-A189页

作者： J. Ferrie M. Shipley F. Cappuccio E. Brunner M. Miller M. Kumari M. Marmot A. Coenen J. L. Castillo F. Araya G. Bustamante L. Montecino C. Torres S. Oporto J. Gronli E. Fiske R. Murison B. Bjorvatn E. Sorensen R. Ursin C. M. Portas S. Rajaraman A. Gribok N. Wesensten T. Balkin J. Reifman N. Dursunoglu S. Ozkurt S. Baser O. Delen S. Sarikaya P. Sadler P. Mitchell D. Françon M. Decobert B. Herve A. Richard G. Griebel P. Avenet B. Scatton G. L. Fur D. Eckert A. Jordan A. Wellman S. Smith A. Malhotra D. White D. Bruck I. Thomas A. Kritikos W. Oertel K. Stiasny-Kolster D. Garcia-Borreguero W. Poewe B. Hoegl R. Kohnen E. Schollmayer J. Keffel C. Trenkwalder A. Valle S. Roizenblatt F. Fregni P. Boggio S. Tufik K. Ward L. Robertson L. Palmer P. Eastwood D. Hillman J. Lee S. Mukherjee V. de Padova G. Barbato G. Ficca I. Zilli P. Salzarulo M. Veldi T. Hion V. Vasar M. Kull L. Nowak J. Davis Y. Latzer O. Tzischinsky S. Crowley M. Carskadon M. Anca-Herschkovitsch D. Frey J. Ortega C. Wiseman C. Farley K. Wright A. Campbell A. Neill K. Spiegel R. Leproult E. Tasali N. Scherberg E. van Cauter A. T. Noradina N. A. Karim I. Norlinah A. A. Raymond R. Sahathevan B. Hamidon E. Werth R. Poryazova R. Khatami C. Bassetti R. G. Beran L. Ainley G. Holand J. Duncan H. Kinney B. Davis B. Hood S. Frey C. Schmidt M. Hofstetter P. Peigneux C. Cajochen W.-P. Hu J.-D. Li C. Zhang L. Boehmer J. Siegel Q.-Y. Zhou Y. Sagawa H. Kondo T. Takemura H. Kanayama Y. Kaneko M. Sato T. Kanbayashi Y. Hishikawa T. Shimizu A. Viola L. James L. Schlangen D.-J. Dijk R. Andretic Y.-C. Kim K.-A. Han F. Jones R. Greenspan L. Sanford L. Yang X. Tang K. Dieter E. Uta H. Sven M. Richard N. Oyane S. Pallesen F. Holsten Y. Inoue M. Fujita N. Emura K. Kuroda N. Uchimura A. Johnston J. Astbury G. Kennedy K. Hoedlmoser M. Schabus T. Pecherstorfer S. Moser G. Gruber P. Anderer W. Klimesch N. Naidoo M. Ferber A. Pack D. Neu O. Mairesse G. Hoffmann A. Dris L. Lambrecht P. Linkowski P. Verbanck O. Le Bon N. Matsuura M. Yamao N. Adachi R. Aritomi Y. Komada H. Tanaka S. Shirak University College London London UK University College London London USA Warwick Medical School London UK Warwick Medical School Coventry USA Radboud University Nijmegen Nijmegen Netherlands Department of Neurology University of Chile Santiago Chile Neurology Service Hospital del Salvador Santiago Chile Family Health Center Juan Pablo II Santiago Chile Department of Biomedicine Section on Physiology Univeristy of Bergen Bergen Norway Department of Public Health and Primary Health Care Univeristy of Bergen Bergen Norway Department of Public Health and Primary Health Care University of Bergen Bergen Norway Norwegian Competence Center for Sleep Disorders Haukeland University Hospital Bergen Norway Department of Child and Adolescent Psychiatry Haukeland University Hospital Univeristy of Bergen Bergen Norway Department of Biomedicine University of Bergen Bergen Norway US Army Medical Research and Materiel Command Fort Detrick Frederick USA Walter Reed Army Institute of Research Silver Spring USA Department of Behavioral Biology Walter Reed Army Institute of Research Silver Spring USA Faculty Department of Pulmonology Pamukkale University Medical Denizli Turkey University of Ballarat Ballarat Australia Sanofi-Aventis Recherche et Developpement Paris France Brigham and Women’s Hospital Harvard Medical School Boston USA The University of Queensland Adelaide Australia School of Psychology University of Queensland Brisbane Australia The University of Queensland Brisbane Australia Victoria University Melbourne Australia Department of Psychology Victoria University Melbourne Australia School of Psychology Victoria University Melbourne Australia Philips-Universität Marburg Germany Philips-Universitaet-Marburg Marburg Germany Instituto de Investigaciones del Sueno Madrid Spain Universitätsklinik für Neurologie Innsbruck Austria Universitaetsklinik fuer Neurologie Innsbruck Austria IMEREM GmbH Nuernberg Germany Schwarz Pharma AG Monheim Germany

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Challenge - Naval force development

引用

Naval Engineers Journal 2004年第3期116卷 57-62页

作者： Hamilton, Charles S. Program Executive Officer for Ships REAR ADMIRAL HAMILTON is a native of Amityville New York. He attended Duke University graduating in May 1974 with a bachelor of science in zoology. He was commissioned in the Navy in May 1974 through the NROTC Program at Duke. Rear Adm. Hamilton's sea tours include electronics material officer and combat information center officer in USS Hawkins (DD 873) (1974 to 1976) fire control officer and missile officer in USS Coontz (DDG 40) (1976 to1978) operations officer in USS Callaghan (DDG 994) (1981 to 1984) executive officer USS Fox (CG 33) (1986 to 1988) and commanding officer USS O'Brien (DD 975) (1991 to 1993). Rear Adm. Hamilton's shore tours include anti-submarine warfare program analyst and administrative assistant to director Program Resource Appraisal Division (OP-91) Office of the Chief of Naval Operations (1984 to 1986) head Aegis Destroyer Section (OP-355F) and financial coordinator Aegis Cruiser Destroyer Branch Office of the Chief of Naval Operations (1988 to 1990) and military staff specialist for naval war-fare in the Office of the Under Secretary of Defense (Acquisition and Technology) (1994 to 1996). In May 1996 Rear Adm. Hamilton became program manager for the arsenal ship which was designed to provide massed precision fires in support of Fleet commander's warfighting requirements. After completing the first two design phases and passing significant acquisition reform lessons learned to the DD 21 Program Office Rear Adm. Hamilton closed down the Arsenal Ship Program in March 1998. From April 1998 to February 2000 Rear Adm. Hamilton served as deputy for Fleet in the Program Executive Office Theater Surface Combatants (PEO TSC-F). In this position he was responsible for Fleet Introduction and Lifetime Support of 120 surface combatants (DDG 51 CG 47 DDG 993 DD 963 FFG 7). Rear Adm. Hamilton served as program executive officer for Surface Strike (PEO (S)) from February 2000 until November 2002. As PEO (S) he managed the Zumwalt-class DD 21/DD (X) N

The challenges which stood as an obstacle to the naval force development are discussed. The main challenge in the national security environment is to be virtually available anywhere in the world at the behest of the n... 详细信息

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