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Strategic legislation for the promotion of university–industry collaborations: a case study of Taiwan

Journal of Technology Transfer 2025年第1期50卷 304-344页

作者： Truong, Thanh Hue Lin, Bou-Wen Tung, Ching-Pin International Degree Program in Climate Change and Sustainable Development National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei106 Taiwan Research Center for Future Earth National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei106 Taiwan Graduate Institute of Business Administration College of Management National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei106 Taiwan National Applied Research Laboratories No. 106 Sec. 2 Heping E. Rd. Da’an Dist. Taipei City106214 Taiwan Department of Bioenvironmental Systems Engineering National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei106 Taiwan

The strategic utilization of technology to enhance industrial competitiveness and product quality is pivotal for economic growth. As universities own more inventions, collaborative efforts between industry and academia become essential for regional competitiveness and overall economic advancement. This study explores Taiwan’s systematic approach to upgrading its infrastructure, emphasizing the significance of University–Industry Collaborations (UIC) in realizing Industry 4.0. Government strategies and policy decisions emerge as key drivers in fostering successful collaborative projects between industry and university teams. The relaxation of restrictions, particularly related to part-time teachers and technology transfer, along with the promotion of corporate programs, effective use of public funding, and the development of an innovative digital platform system for UIC, collectively contribute to establishing a robust university–industry cooperation mechanism. This mechanism has contributed to Taiwan’s move towards new digital advances in innovation and entrepreneurship, fostering industrial leadership and efficient governance. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.

关键词： Technology transfer

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Influence of Different Mango Phenological Stages on Fruit Fly Populations in Mango Orchards in Northern Côte d’Ivoire

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Agricultural Sciences 2024年第11期15卷 1305-1314页

作者： Charles Konan Kouakou Adama Coulibaly Fougnigue Edwige Yeo Magloire Yves Minhibo Ossey Robert N’Depo N’Klo Hala Mudde Barnabas National Agricultural Research Center Korhogo Regional Division Lataha Research Station Cashew Mango Papaya Program Abidjan Cte dIvoire UFR Ingnierie Agronomie Foresterie et Environnement Universit de Man (UM) Man Cte dIvoire Agricultural Production Improvement Laboratory University Jean Lorougnon Gud Daloa Cte dIvoire Ngetta Zonal Agricultural Research and Development Institute National Agricultural Research Organization (NARO) Lira Uganda

Côte d’Ivoire is the third largest supplier of mangoes to the European market, after Brazil and Peru, and the leading exporter of mangoes to the African market. However, mango production is faced with the problem of fruit flies, which cause yields to fall. In order to combat fruit flies, a study was launched into the early detection of fruit flies at different phenological stages of the mango tree. The overall aim of the study is to help improve mango productivity through early detection of fruit flies at different phenological stages. Accordingly, a trapping system containing sexual attractants and insecticides was set up in the four cardinal directions of the mango orchard. Insects were collected once a week during the vegetative, flowering, mango development and mango ripening stages. Twelve fruit fly species in four genera and seven species were identified, with a high abundance of Bactrocera dorsalis ((265.64 ± 132.82) individuals) and Ceratitis cosyra ((171.87 ± 85.94) individuals). Fruit flies were most abundant at the maturity stage, with a high abundance of Bactrocera dorsalis species ((129.20 ± 46.15) individuals) and at the vegetative stage ((597.80 ± 214.07) individuals), and a high abundance of Ceratitis cosyra species at the flowering (111.26 ± 33.71) and mango development ((187.47 ± 62.64) individuals) stages. In conclusion, the phenological stages of mango influence the population of fruit flies in mango orchards.

关键词： Trapping Device Detection Vegetative Flowering Mango development Maturity

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Natural products from the culture broth of an actinobacteria Streptomyces sp. M5205 and evaluation of their antifungal activity

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Phytochemistry Letters 2024年 59卷 59-63页

作者： Chen, Jih-Jung Cheng, Ming-Jen Tseng, Min Wu, Ming-Der Weng, Jing-Ru Department of Pharmacy School of Pharmaceutical Sciences National Yang Ming Chiao Tung University (NYCU) Taipei 112304 Taiwan Department of Medical Research China Medical University Hospital China Medical University Taichung 404333 Taiwan Department of Life Science Fu Jen Catholic University New Taipei City 24205 Taiwan Bioresource Collection and Research Center Food Industry Research and Development Institute Hsinchu 300193 Taiwan Department of Marine Biotechnology and Resources National Sun Yat-sen University Kaohsiung 80424 Taiwan Doctoral Degree Program in Marine Biotechnology National Sun Yat-sen University Kaohsiung 80424 Taiwan

One previously undescribed trinorditerpene analog, M5205 (1), together with four known triterpenes, betulinic acid (2), betulin (3), messagenic acid D (4), and betulonic acid (5), were isolated from the EtOAc extract of the culture broth of the actinomycete Streptomyces sp. M5205. One previously undescribed sesquiterpene analog, M5205 (1), together with four known analogs, betulinic acid (2), betulin (3), messagenic acid D (4), and betulonic acid (5), were isolated from the EtOAc extract of the culture broth of the actinomycete Streptomyces sp. M5205. The structures of all isolates were elucidated on the basis of extensive analyses of spectroscopic data and comparison with literature data. Their antifungal activity was also evaluated. Our results showed that 4 constituents (Compounds 1 & 335) possessed mild antifungal activity against Fusarium sp. LC8, Neopestalotiopsis sp. BCRC 35002, and Colletotrichum gloeosporioides BCRC 35178. It is worth mentioning that the chemical composition of the type strain Streptomyces sp. M5205 has never been studied. © 2023

关键词： Actinobacteria Antifungal Secondary metabolites Sesquiterpene Streptomyces sp. M5205

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Stiffness of In-Situ Formed Interleaving Polymeric Nanofiber-Epoxy Nanocomposites

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Open Journal of Composite Materials 2024年第4期14卷 147-157页

作者： Farzin Javanshour Kaan Bilge Abdul Bari Abdul Raheman Melih Papila VTT Technical Research Centre of Finland Ltd. Tampere Finland Insight Technology Development and Consultancy Kozyata Istanbul Trkiye Materials Science & Nano Engineering Program Sabanci University Istanbul Trkiye Department of Mechanical Engineering California State University Northridge Northridge USA

This study proposes a facile, but precise method to back-calculate the effective modulus of nanocomposite interleaving plies. Adaptation of a conventional dry-reinforcement resin film infusion (RFI) approach allows interleaving neat epoxy layers (NE) with the epoxy-infused nanofibrous plies (XE) of constant thickness. The final cured nanocomposite laminate thus has the form (NE/XE)n, where “n” denotes the number of the repeats and enables clear distinction of the nanocomposite interlayers through the thickness. Mechanical testing of neat epoxy and laminated nanocomposite specimens can be coupled with the classical lamination theory for back-calculating in-plane elastic modulus of the individual epoxy-infused nanofibrous plies (EXE). Finite element analysis (FEA) and testing the laminated nanocomposite subject to flexural loading (3-point bending) are proposed to validate the analytically back-calculated EXE. It is shown that the FEA prediction incorporating EXE and testing for flexural modulus of (NE/XE)20 laminated nanocomposites correlate well and the results are within 5%. This finding suggests that the back-calculation scheme reported herein would be attractive for accurately determining the properties of an individual nanocomposite building block layer. The proposed framework is beneficial for modelling laminated structural composites incorporating XE-like nanocomposite interlayers.

关键词： Lamination Theory Resin Film Infusion Electrospun Nanofibers Mechanical Properties

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The effects of commercialization of cereal crops on multidimensional poverty and vulnerability to multidimensional poverty among farm households in Ethiopia

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development Studies research 2021年第1期8卷 378-395页

作者： Birhanu, Fisseha Zegeye Tsehay, Abrham Seyoum Bimerew, Dawit Alemu Ethiopian Institute of Agricultural Research (EIAR) Addis Ababa Ethiopia Center for Rural Development Studies Addis Ababa University Addis Ababa Ethiopia BENEFIT Partnership Program Addis Ababa Ethiopia

The study examined the effects of cereal commercialization on multidimensional poverty among farm households in teff-based mixed farming areas of Ethiopia. It applied instrumental Tobit regression and conditional mixed-process models to estimate the overall and dimensional effects of commercialization on household multidimensional poverty (MP) and vulnerability to multidimensional poverty (VMP). The result showed that the mean commercialization scale of the farm households was 38%. The headcount ratio (H) was found to be 58%, implying the poverty situation continues to pose major challenges upon the well-being of farm households. The average estimate of multidimensional poverty index (MPI) and household vulnerability to MP among sampled rural farm households was 0.31 and 0.52, respectively, with a statistically significant mean difference of commercialization status being at 1% level. Ceteris Paribus Assumption, a 10% increase in the degree of cereal commercialization is likely to reduce MPI deprivation, MPI poverty, and VMP by 5.4%, 16.3%, and 2.2%, respectively. Cereal commercialization also significantly reduces MPI dimensions that are measured exclusively through living standard and wealth dimensions. Thus, the commercial transformation of smallholders through a well-integrated market and improved infrastructure are key areas of policy intervention to improve the well-being of farm households in rural areas. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

关键词： Cereal commercialization Ethiopia multidimensional poverty and vulnerability

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The AT-hook protein AHL29 promotes Bacillus subtilis colonization by suppressing SWEET2-mediated sugar retrieval in Arabidopsis roots

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Plant Cell and Environment 2024年第4期47卷 1084-1098页

作者： Wu, Yun-Chien Yu, Chien-Wen Chiu, Jo-Yu Chiang, Yu-Hsuan Mitsuda, Nobutaka Yen, Xu-Chen Huang, Tzu-Pi Chang, Tzu-Fang Yen, Cen-Jie Guo, Woei-Jiun Department of Biotechnology and Bioindustry Sciences National Cheng Kung University Tainan Taiwan Bioproduction Research Institute National Institute of Advanced Industrial Science and Technology (AIST) Tsukuba Ibaraki Japan Department of Plant Pathology National Chung Hsing University Taichung Taiwan Innovation and Development Center of Sustainable Agriculture National Chung Hsing University Taichung Taiwan Master and Doctoral Degree Program in Plant Health Care Academy of Circular Economy National Chung Hsing University Nantou Taiwan

Beneficial Bacillus subtilis (BS) symbiosis could combat root pathogenesis, but it relies on root-secreted sugars. Understanding the molecular control of sugar flux during colonization would benefit biocontrol applications. The SWEET (Sugar Will Eventually Be Exported Transporter) uniporter regulates microbe-induced sugar secretion from roots;thus, its homologs may modulate sugar distribution upon BS colonization. Quantitative polymerase chain reaction revealed that gene transcripts of SWEET2, but not SWEET16 and 17, were significantly induced in seedling roots after 12 h of BS inoculation. Particularly, SWEET2-β-glucuronidase fusion proteins accumulated in the apical mature zone where BS abundantly colonized. Yet, enhanced BS colonization in sweet2 mutant roots suggested a specific role for SWEET2 to constrain BS propagation, probably by limiting hexose secretion. By employing yeast one-hybrid screening and ectopic expression in Arabidopsis protoplasts, the transcription factor AHL29 was identified to function as a repressor of SWEET2 expression through the AT-hook motif. Repression occurred despite immunity signals. Additionally, enhanced SWEET2 expression and reduced colonies were specifically detected in roots of BS-colonized ahl29 mutant. Taken together, we propose that BS colonization may activate repression of AHL29 on SWEET2 transcription that would be enhanced by immunity signals, thereby maintaining adequate sugar secretion for a beneficial Bacillus association. © 2023 John Wiley & Sons Ltd.

关键词： AT-hook motif rhizobacteria sugar transporter SWEET symbiosis

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Nanotechnology-based gene therapy as a credible tool in the treatment of Alzheimer’s disease

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Neural Regeneration research 2023年第10期18卷 2127-2133页

作者： Aziz Unnisa Nigel H.Greig Mohammad Amjad Kamal Department of Pharmaceutical Chemistry College of PharmacyUniversity of HailHailSaudi Arabia Drug Design&Development Section Translational Gerontology BranchIntramural Research ProgramNational Institute on AgingNational Institutes of HealthBaltimoreMDUSA Institutes for Systems Genetics Frontiers Science Center for Disease-related Molecular NetworkWest China HospitalSichuan UniversityChengduSichuan ProvinceChina King Fahd Medical Research Center King Abdulaziz UniversityJeddahSaudi Arabia Department of Pharmacy Faculty of Allied Health SciencesDaffodil International UniversityDhakaBangladesh Enzymoics Novel Global Community Educational FoundationHebershamNSWAustralia

Toxic aggregated amyloid-βaccumulation is a key pathogenic event in Alzheimer’s *** approaches have focused on the suppression,deferral,or dispersion of amyloid-βfibers and *** therapy has evolved as a potential therapeutic option for treating Alzheimer’s disease,owing to its rapid advancement over the recent *** interfering ribonucleic acid has recently garnered considerable attention in gene therapy owing to its ability to down-regulate genes with high sequence specificity and an almost limitless number of therapeutic targets,including those that were once considered ***,lackluster cellular uptake and the destabilization of small interfering ribonucleic acid in its biological environment restrict its therapeutic application,necessitating the development of a vector that can safeguard the genetic material from early destruction within the bloodstream while effectively delivering therapeutic genes across the bloodbrain *** has emerged as a possible solution,and several delivery systems utilizing nanoparticles have been shown to bypass key challenges regarding small interfering ribonucleic acid *** reducing the enzymatic breakdown of genetic components,nanomaterials as gene carriers have considerably enhanced the efficiency of gene ***,polymeric nanoparticles,magnetic nanoparticles,dendrimers,and micelles are examples of nanocarriers that have been designed,and each has its own set of ***,recent advances in the specific delivery of neurotrophic compounds via gene therapy have provided promising results in relation to augmenting cognitive *** this paper,we highlight the use of different nanocarriers in targeted gene delivery and small interfering ribonucleic acid-mediated gene silencing as a potential platform for treating Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β BACE1 gene silencing gene therapy nanoparticle neurotrophins small interfering ribonucleic acid

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Ajuga taiwanensis Extract Promotes Wound-healing via Activation of PDGFR/MAPK Pathway

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Planta Medica 2024年第12期90卷 949-958页

作者： Hsu, Wei-Hsiang Cheng, Jing-Jy Wu, Ching-Fen Lin, Yun-Lian Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources China Medical University Taichung Taiwan Institute of Biopharmaceutical Sciences National Yang-Ming University Taipei Taiwan National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei Taiwan Program in Clinical Drug Development of Herbal Medicine College of Pharmacy Taipei Medical University Taipei Taiwan Department of Veterinary Medicine National Chiayi University Taiwan Department of Pharmacy National Taiwan University Taipei Taiwan

Chronic and prolonged wounds are a serious public problem that may severely affect the quality of life and result in psychological pressure. Fibroblasts play a crucial role in the wound process and in skin pathology. Herbal drugs have long been used for wound care worldwide. Ajuga taiwanensis (Lamiaceae) is a folk medicine for antipyretics, anti-inflammation, and reducing swelling in Taiwan. This study aimed to investigate the effect of A. taiwanensis in wound healing and the underlying mechanisms. Under human dermal fibroblast (HDF) wound-healing activity-guided fractionation, we found that a sub-fraction (AT-M) of A. taiwanensis extract (AT) and the major ingredients significantly promoted wound healing and decreased IL-1β and - 6 expressions on HDFs. Furthermore, the fraction of AT-M enhanced wound healing on C57BL/6 mouse skins, increased PDGFR expressions, and activated the PDGFR/MAPK pathway. Taken together, A. taiwanensis extracts promote wound healing by the PDGFR pathway and lead to enhanced cell spreading and motility, thereby having a possible beneficial effect on wound healing. © 2024. Thieme. All rights reserved.

关键词： Ajuga taiwanensis human dermal fibroblasts Lamiaceae PDGF receptor wound healing

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research on Submarine Cable Anchor Damage Monitoring Technology Based on a Hybrid Brillouin and Rayleigh Distributed Sensing System

Research on Submarine Cable Anchor Damage Monitoring Technol...

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International Conference on Optical Communications and Networks (ICOCN)

作者： Yining Zhang Xiaohui Tang Meng Xia Yilong Huang Zhenjin Cen Yu Han Hongwei Li Yongkang Dong CSG EHV Electric Power Research Institute Guangzhou China National Key Research and Development Program of China Harbin Institute of Technology Harbin China Guangzhou Bureau EHV Transmission Company of China Southern Power Grid Co. Ltd. Guangzhou China

ISBN: (数字)9798350367652

ISBN: (纸本)9798350367669

Submarine cables are critical infrastructure for global communication and energy transmission. However, they are susceptible to damage from anchors, fishing activities, and natural phenomena. This study developed and validated a hybrid Brillouin and Rayleigh distributed sensing system for monitoring submarine cable anchor damage. By integrating Brillouin Optical Time-Domain Analysis (BOTDA) and phase-sensitive optical time-domain reflectometry ( $\Phi$ -OTDR) technologies, we achieved high sensitivity and spatial resolution measurements of cable strain and vibration with a measurement length of 40 kilometers, a strain measurement variance accuracy of 0.65 $\mu\varepsilon$ and spatial resolution of 1m. Experimental results showed that the system could accurately detect and quantify cable strain and vibration responses caused by anchor impacts, hooking, and dragging events. Additionally, the vibration signals enabled tracking of the anchor's movement path. This hybrid monitoring method provides a reliable solution for real-time, precise detection of potential threats to submarine cables, enhancing their protection and reducing operational disruptions and maintenance costs.

关键词： Underwater cables Vibrations Accuracy Scattering Optical variables measurement Vibration measurement Strain measurement

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Insect Classification Using Spatial Pyramid Pooling and Convolution Neural Network

Insect Classification Using Spatial Pyramid Pooling and Conv...

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IEEE Asia-Pacific Conference on Circuits and Systems

作者： Chang-Yu Wu Song-Min Ke Hoh-Siang Liao Chen-Hua Chen Ying-Hsiu Hung Shin-Chi Lai Department of Automation Engineering Master’s Program National Formosa University Huwei Taiwan Department of Automation Engineering National Formosa University Huwei Taiwan Doctoral Degree Program in Smart Industry Technology Research and Development National Formosa University Huwei Taiwan Dept. Automation Engineering & Smart Machinery and Intelligent Manufacturing Research Center National Formosa University Huwei Taiwan

ISBN: (数字)9798350378771

ISBN: (纸本)9798350378788

This study aims to enhance the accuracy and efficiency of insect classification using spatial pyramid pooling convolutional neural networks (SPP-CNN). Improving traditional convolutional neural networks has resulted in poor performance when dealing with the diversity of insects and images of various sizes. The dataset, provided by a collaborating company, includes six different insect categories. Given the relatively limited number of samples in the existing dataset, we employed various data augmentation techniques to enrich our training samples, such as sharpening, adding noise, resizing, adjusting brightness, and randomly rotating images. Experiments demonstrate that SPP-CNN shows superior performance in insect classification tasks compared to efficientNetV2. The proposed architecture has achieved an accuracy rate of $83.8 \%$, which is $3.9 \%$ higher than the $79.9 \%$ accuracy of EfficientNetV2 architectures. This improvement indicates that incorporating the spatial pyramid pooling layer significantly enhances the accuracy of insect image classification. Moreover, the adaptability of SPP-CNN to various image resolutions without the need for retraining significantly boosts its practicality for real-world applications.

关键词： Training Accuracy Image resolution Insects Noise Neural networks Data models Convolutional neural networks Integrated circuit modeling Image classification

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