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arXiv 2022年

作者： Li, Lei Wu, Fuping Wang, Sihan Luo, Xinzhe Martín-Isla, Carlos Zhai, Shuwei Zhang, Jianpeng Liu, Yanfei Zhang, Zhen Ankenbrand, Markus J. Jiang, Haochuan Zhang, Xiaoran Wang, Linhong Arega, Tewodros Weldebirhan Altunok, Elif Zhao, Zhou Li, Feiyan Ma, Jun Yang, Xiaoping Puybareau, Elodie Oksuz, Ilkay Bricq, Stephanie Li, Weisheng Punithakumar, Kumaradevan Tsaftaris, Sotirios A. Schreiber, Laura M. Yang, Mingjing Liu, Guocai Xia, Yong Wang, Guotai Escalera, Sergio Zhuang, Xiahai School of Data Science Fudan University Shanghai China School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Departament de Matemàtiques & Informàtica Universitat de Barcelona Barcelona Spain Computer Vision Center Universitat Autònoma de Barcelona Spain School of Mechanical and Electrical Engineering University of Electronic Science and Technology of China Chengdu China School of Computer Science and Engineering Northwestern Polytechnical University Xi'An China College of Electrical and Information Engineering Hunan University Changsha China National Engineering Laboratory for Robot Visual Perception and Control Technology Changsha China College of Physics and Information Engineering Fuzhou University Fuzhou China Comprehensive Heart Failure Center Wuerzburg University Hospitals Wuerzburg Germany School of Engineering University of Edinburgh Edinburgh United Kingdom School of Robotics Xi'an Jiaotong-Liverpool University Suzhou China Department of Electrical and Computer Engineering University of California Los Angeles United States Department of Radiology and Diagnostic Imaging University of Alberta Edmonton Canada Chongqing Key Laboratory of Image Cognition Chongqing University of Posts and Telecomm-Unications Chongqing China ImViA Laboratory Université Bourgogne Franche-Comté Dijon France Computer Engineering Department Istanbul Technical University Istanbul Turkey Le Kremlin-Bicêtre France Department of Mathematics Nanjing University of Science and Technology Nanjing China Department of Mathematics Nanjing University Nanjing China

Assessment of myocardial viability is essential in diagnosis and treatment management of patients suffering from myocardial infarction, and classification of pathology on myocardium is the key to this assessment. This work defines a new task of medical image analysis, i.e., to perform myocardial pathology segmentation (MyoPS) combining three-sequence cardiac magnetic resonance (CMR) images, which was first proposed in the MyoPS challenge, in conjunction with MICCAI 2020. The challenge provided 45 paired and pre-aligned CMR images, allowing algorithms to combine the complementary information from the three CMR sequences for pathology segmentation. In this article, we provide details of the challenge, survey the works from fifteen participants and interpret their methods according to five aspects, i.e., preprocessing, data augmentation, learning strategy, model architecture and post-processing. In addition, we analyze the results with respect to different factors, in order to examine the key obstacles and explore potential of solutions, as well as to provide a benchmark for future research. We conclude that while promising results have been reported, the research is still in the early stage, and more in-depth exploration is needed before a successful application to the clinics. Note that MyoPS data and evaluation tool continue to be publicly available upon registration via its homepage (***/zhuangxiahai/0/myops20/). © 2022, CC BY-NC-SA.

关键词： Magnetic resonance imaging

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LYSTO: The Lymphocyte Assessment Hackathon and Benchmark Dataset

arXiv

引用

arXiv 2023年

作者： Jiao, Yiping van der Laak, Jeroen Albarqouni, Shadi Li, Zhang Tan, Tao Bhalerao, Abhir Ma, Jiabo Sun, Jiamei Pocock, Johnathan Pluim, Josien P.W. Koohbanani, Navid Alemi Bashir, Raja Muhammad Saad Raza, Shan E Ahmed Liu, Sibo Graham, Simon Wetstein, Suzanne Khurram, Syed Ali Watson, Thomas Rajpoot, Nasir Veta, Mitko Ciompi, Francesco Department of Pathology Radboud University Medical Center Nijmegen Netherlands School of Artificial Intelligence Nanjing University of Information Science Technology China Center for Medical Image Science and Visualization Linköping University Linköping Sweden Helmholtz AI Helmholtz Zentrum München Nuerherberg 85764 Germany Faculty of Informatics Technical University of Munich Garching85748 Germany College of Aerospace Science and Engineering National University of Defense Technology China Hunan Provincial Key Laboratory of Image Measurement and Vision Navigation China Macao Polytechnic University China Department of Computer Science University of Warwick Coventry United Kingdom Huazhong University of Science and Technology China Singapore Medical Image Analysis Group Department of Biomedical Engineering Eindhoven University of Technology Eindhoven Netherlands School of Clinical Dentistry University of Sheffield Sheffield United Kingdom United Kingdom

We introduce LYSTO, the Lymphocyte Assessment Hackathon, which was held in conjunction with the MICCAI 2019 Conference in Shenzen (China). The competition required participants to automatically assess the number of lymphocytes, in particular T-cells, in histopathological images of colon, breast, and prostate cancer stained with CD3 and CD8 immunohistochemistry. Differently from other challenges setup in medical image analysis, LYSTO participants were solely given a few hours to address this problem. In this paper, we describe the goal and the multi-phase organization of the hackathon;we describe the proposed methods and the on-site results. Additionally, we present post-competition results where we show how the presented methods perform on an independent set of lung cancer slides, which was not part of the initial competition, as well as a comparison on lymphocyte assessment between presented methods and a panel of pathologists. We show that some of the participants were capable to achieve pathologist-level performance at lymphocyte assessment. After the hackathon, LYSTO was left as a lightweight plug-and-play benchmark dataset on grand-challenge website, together with an automatic evaluation platform. LYSTO has supported a number of research in lymphocyte assessment in oncology. LYSTO will be a long-lasting educational challenge for deep learning and digital pathology, it is available at https://***/.MSC Codes 68T07 © 2023, CC BY.

关键词： Pathology

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Wi-Fi Signal Analysis for Heartbeat and Metal Detection: A Comparative Study of Reliable Contactless Systems 6

Wi-Fi Signal Analysis for Heartbeat and Metal Detection: A C...

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6th International Conference on Dependable Systems and Their Applications, DSA 2019

作者： Khan, Faiza Alam Bhuiyan, Md Zakirul Islam, Md Monirul Wang, Tian Zaman, Aliuz Tao, Hai Fordham University Department of Computer and Information Sciences New York United States Huaqiao University College of Computer Science and Technology Key Laboratory of Computer Vision and Machine Learning Huaqiao361021 China School of Computer Science Baoji University of Arts and Sciences Baoji Shaanxi721007 China

ISBN: (纸本)9781728160573

In this survey paper, we present various proposals of Wi-Fi applications which can benefit society, namely through detection of vital signs and detection of suspicious objects. Based on the previous research conducted in this field, we analyze how heart rate detection using Wi-Fi dependent technologies compare to older, sensor-based methods and the necessity of modern implementations especially in the medical field. People can have heart problems such as tachycardia and bradycardia at any instance, thus systems which do not require contact are most practical in detection of vital sign irregularities. Sensorbased systems may depend on Wi-Fi technologies only for the communication between different components in the system, such as in the Message Queuing Telemetry Transport System. However, the presence of a sensor in these systems can be replaced by Wi-Fi technologies to detect the presence of people and monitor their corresponding heart rates in a contactless manner. Additionally, Wi-Fi dependent systems such as Vital Radio and Wi-Sleep can monitor the heart rates of multiple people at once. Therefore contactless, Wi-Fi based systems are most efficient and practical for daily use. Moreover, although contactless systems demonstrate the benefits of technological advancements, these systems can still be further improved since they tend to produce higher accuracy rates from shorter distances, as demonstrated by the UWB radar system and the Fresnel model. Contactless systems can be enhanced to detect multiple users at once at extended distances. After providing details of contact requiring and contactless systems for heart rate detection, we also provide other useful applications of Wi-Fi technology, such as in the field of metal detection, human fall detection, etc. © 2020 IEEE.

关键词： Heart

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Image-guided breast biopsy of MRI-visible lesions with a hand-mounted motorised needle steering tool

arXiv

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arXiv 2021年

作者： Lagomarsino, Marta Groenhuis, Vincent Casadio, Maura Welleweerd, Marcel K. Siepel, Françoise J. Stramigioli, Stefano Laboratory Faculty of Electrical Engineering Mathematics and Computer Science University of Twente Drienerlolaan 5 Enschede7522NB Netherlands Department of Informatics Bioengineering Robotics and Systems Engineering University of Genoa Via Opera Pia 13 Genoa16145 Italy Department of Advanced Robotics Istituto Italiano di Tecnologia Genoa Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy

A biopsy is the only diagnostic procedure for accurate histological confirmation of breast cancer. When sonographic placement is not feasible, a Magnetic Resonance Imaging(MRI)-guided biopsy is often preferred. The lack of real-time imaging information and the deformations of the breast make it challenging to bring the needle precisely towards the tumour detected in pre-interventional Magnetic Resonance (MR) images. The current manual MRI-guided biopsy workflow is inaccurate and would benefit from a technique that allows real-time tracking and localisation of the tumour lesion during needle insertion. This paper proposes a robotic setup and software architecture to assist the radiologist in targeting MR-detected suspicious tumours. The approach benefits from image fusion of preoperative images with intraoperative optical tracking of markers attached to the patient's skin. A hand-mounted biopsy device has been constructed with an actuated needle base to drive the tip toward the desired direction. The steering commands may be provided both by user input and by computer guidance. The workflow is validated through phantom experiments. On average, the suspicious breast lesion is targeted with a radius down to 2.3 mm. The results suggest that robotic systems taking into account breast deformations have the potentials to tackle this clinical challenge. Copyright © 2021, The Authors. All rights reserved.

关键词： Biopsy

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Application of Graph-Curvature Features in Auxiliary Diagnosis for Histopathological Image Identification of Gastric Cancer

SSRN

引用

SSRN 2023年

作者： He, Ruilin Li, Chen Yang, Xinyi Yang, Jinzhu Jiang, Tao Grzegorzek, Marcin Sun, Hongzan Microscopic Image and Medical Image Analysis Group College of Medicine and Biological Information Engineering Northeastern University Shenyang China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Liaoning Shenyang China School of Intelligent Medicine Chengdu University of Traditional Chinese Medicine Chengdu China International Joint Institute of Robotics and Intelligent Systems Chengdu University of Information Technology Chengdu China Institute for Medical Informatics University of Luebeck Luebeck Germany Department of Knowledge Engineering University of Economics in Katowice Katowice Poland Shengjing Hospital of China Medical University Shenyang China School of Computer Science and Engineering

Background: Histopathology diagnosis is often regarded as the final diagnostic method for malignant tumors, but it has some drawbacks. This paper explores a computer-aided diagnostic method that can identify benign and malignant gastric cancer with histopathology images. Method: This article obtains the most suitable process through multiple experiments, compared multiple methods and features for classification. Firstly, the U-net is applied to segment the image. Next, the nucleus is extracted from the segmented image and the Minimum Spanning Tree (MST) diagram structure is drawn. The third step is to extract the graph-curvature features of histopathology image according to the MST image. Finally, by inputting graph-curvature features into the classifier, the recognition results for benign or malignant can be obtained. Result: During the experiment, we use various methods for comparison. In the image segmentation stage, U-net, watershed algorithm and Otsu threshold segmentation methods are used respectively. Combined with multiple indicators, we find that the U-net method is the most suitable for segmentation of histopathology images. In the feature extraction stage, in addition to extracting graph-edge feature and graph-curvature feature, several basic image features are also extracted, including Red, Green, Blue feature, Gray-Level Co-occurrence Matrix feature, Histogram of Oriented Gradient feature, and Local Binary Pattern feature. In the classifier design stage, we experimented with various methods, such as Support vector machine (SVM), Random forest, Artificial Neural Network, K Nearest Neighbors, VGG-16 and Inception-V3. Through the comparison and analysis, the classification results with an accuracy of 98.57% can be obtained by inputting the graph-curvature feature into SVM classifier. Conclusion: This paper has created a unique feature, graph-curvature feature based on MST to represent and analyze histopathology images. This graph-based feature can be used

关键词： Local binary pattern

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Placental Vessel Segmentation and Registration in Fetoscopy: Literature Review and MICCAI FetReg2021 Challenge Findings

arXiv

引用

arXiv 2022年

作者： Bano, Sophia Casella, Alessandro Vasconcelos, Francisco Qayyum, Abdul Benzinou, Abdesslam Mazher, Moona Meriaudeau, Fabrice Lena, Chiara Cintorrino, Ilaria Anita De Paolis, Gaia Romana Biagioli, Jessica Grechishnikova, Daria Jiao, Jing Bai, Bizhe Qiao, Yanyan Bhattarai, Binod Gaire, Rebati Raman Subedi, Ronast Vazquez, Eduard Plotka, Szymon Lisowska, Aneta Sitek, Arkadiusz Attilakos, George Wimalasundera, Ruwan David, Anna L. Paladini, Dario Deprest, Jan De Momi, Elena Mattos, Leonardo S. Moccia, Sara Stoyanov, Danail Department of Computer Science University College London United Kingdom Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Italy The BioRobotics Institute Department of Excellence in Robotics and AI Scuola Superiore Sant'Anna Italy Fetal Medicine Unit Elizabeth Garrett Anderson Wing University College London Hospital United Kingdom EGA Institute for Women's Health Faculty of Population Health Sciences University College London United Kingdom Department of Development and Regeneration University Hospital Leuven Belgium Department of Fetal and Perinatal Medicine Istituto Giannina Gaslini Italy ENIB UMR CNRS 6285 LabSTICC 29238 France Department of Computer Engineering and Mathematics University Rovira i Virgili Spain ImViA Laboratory University of Bourgogne Franche-Comté France Physics Department Lomonosov Moscow State University Russia Fudan University China Medical Computer Vision and Robotics Group Department of Mathematical and Computational Sciences University of Toronto Canada Co. Ltd China NepAL Applied Mathematics and Informatics Institute for Research Nepal Redev Technology United Kingdom Sano Center for Computational Medicine Poland Quantitative Healthcare Analysis Group Informatics Institute University of Amsterdam Amsterdam Netherlands Center for Advanced Medical Computing and Simulation Massachusetts General Hospital Harvard Medical School BostonMA United States

Fetoscopy laser photocoagulation is a widely adopted procedure for treating Twin-to-Twin Transfusion Syndrome (TTTS). The procedure involves photocoagulation pathological anastomoses to restore a physiological blood exchange among twins. The procedure is particularly challenging, from the surgeon's side, due to the limited field of view, poor manoeuvrability of the fetoscope, poor visibility due to amniotic fluid turbidity, and variability in illumination. These challenges may lead to increased surgery time and incomplete ablation of pathological anastomoses, resulting in persistent TTTS. computer-assisted intervention (CAI) can provide TTTS surgeons with decision support and context awareness by identifying key structures in the scene and expanding the fetoscopic field of view through video mosaicking. Research in this domain has been hampered by the lack of high-quality data to design, develop and test CAI algorithms. Through the Fetoscopic Placental Vessel Segmentation and Registration (FetReg2021) challenge, which was organized as part of the MICCAI2021 Endoscopic vision (EndoVis) challenge, we released the first large-scale multi-center TTTS dataset for the development of generalized and robust semantic segmentation and video mosaicking algorithms with a focus on creating drift-free mosaics from long duration fetoscopy videos. For this challenge, we released a dataset of 2060 images, pixel-annotated for vessels, tool, fetus and background classes, from 18 in-vivo TTTS fetoscopy procedures and 18 short video clips of an average length of 411 frames for developing placental scene segmentation and frame registration for mosaicking techniques. Seven teams participated in this challenge and their model performance was assessed on an unseen test dataset of 658 pixel-annotated images from 6 fetoscopic procedures and 6 short clips. The challenge provided an opportunity for creating generalized solutions for fetoscopic scene understanding and mosaicking. In this paper,

关键词： Pixels

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Enhancing Diagnostic Reliability of Foundation Model with Uncertainty Estimation in OCT Images

arXiv

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arXiv 2024年

作者： Peng, Yuanyuan Lin, Aidi Wang, Meng Lin, Tian Zou, Ke Cheng, Yinglin Shi, Tingkun Liao, Xulong Feng, Lixia Liang, Zhen Chen, Xinjian Fu, Huazhu Chen, Haoyu School of Biomedical Engineering Anhui Medical University Anhui Hefei230032 China Joint Shantou International Eye Center Shantou University The Chinese University of Hong Kong Guangdong Shantou515041 China Beth Israel Deaconess Medical Center Harvard Medical School 330 Brookline Ave BostonMA02215 United States National Key Laboratory of Fundamental Science on Synthetic Vision The College of Computer Science Sichuan University Sichuan Chengdu610065 China Department of Ophthalmology First Affiliated Hospital of Anhui Medical University Anhui Hefei China School of Electronics and Information Engineering Soochow University Jiangsu Suzhou215006 China State Key Laboratory of Radiation Medicine and Protection Soochow University Suzhou Suzhou215006 China 1 Fusionopolis Way #16-16 Connexis Singapore138632 Singapore

Inability to express the confidence level and detect unseen classes has limited the clinical implementation of artificial intelligence in the real-world. We developed a foundation model with uncertainty estimation (FMUE) to detect 11 retinal conditions on optical coherence tomography (OCT). In the internal test set, FMUE achieved a higher F1 score of 96.76% than two state-of-the-art algorithms, RETFound and UIOS, and got further improvement with thresholding strategy to 98.44%. In the external test sets obtained from other OCT devices, FMUE achieved an accuracy of 88.75% and 92.73% before and after thresholding. Our model is superior to two ophthalmologists with a higher F1 score (95.17% vs. 61.93% &71.72%). Besides, our model correctly predicts high uncertainty scores for samples with ambiguous features, of non-target-category diseases, or with low-quality to prompt manual checks and prevent misdiagnosis. FMUE provides a trustworthy method for automatic retinal anomalies detection in the real-world clinical open set environment. Copyright © 2024, The Authors. All rights reserved.

关键词： Optical tomography

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Uncertainty-inspired Open Set Learning for Retinal Anomaly Identification

arXiv

引用

arXiv 2023年

作者： Wang, Meng Lin, Tian Wang, Lianyu Lin, Aidi Zou, Ke Xu, Xinxing Zhou, Yi Peng, Yuanyuan Meng, Qingquan Qian, Yiming Deng, Guoyao Wu, Zhiqun Chen, Junhong Lin, Jianhong Zhang, Mingzhi Zhu, Weifang Zhang, Changqing Zhang, Daoqiang Goh, Rick Siow Mong Liu, Yong Pang, Chi Pui Chen, Xinjian Chen, Haoyu Fu, Huazhu 1 Fusionopolis Way #16-16 Connexis Singapore138632 Singapore Joint Shantou International Eye Center Shantou University the Chinese University of Hong Kong Medical College Shantou University Guangdong515041 China College of Computer Science and Technology Nanjing University of Aeronautics and Astronautics Jiangsu211100 China National Key Laboratory of Fundamental Science on Synthetic Vision the College of Computer Science Sichuan University Sichuan610065 China School of Electronics and Information Engineering Soochow University Jiangsu215006 China School of Biomedical Engineering Anhui Medical University Anhui230032 China Longchuan People’s Hospital Heyuan China Puning People’s Hospital Jieyang China Haifeng PengPai Memory Hospital Shanwei China College of Intelligence and Computing Tianjin University Tianjin300350 China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong State Key Laboratory of Radiation Medicine and Protection Soochow University Suzhou215006 China

Failure to recognize samples from the classes unseen during training is a major limitation of artificial intelligence in the real-world implementation for recognition and classification of retinal anomalies. We established an uncertainty-inspired open-set (UIOS) model, which was trained with fundus images of 9 retinal conditions. Besides assessing the probability of each category, UIOS also calculated an uncertainty score to express its confidence. Our UIOS model with thresholding strategy achieved an F1 score of 99.55%, 97.01% and 91.91% for the internal testing set, external target categories (TC)-JSIEC dataset and TC-unseen testing set, respectively, compared to the F1 score of 92.20%, 80.69% and 64.74% by the standard AI model. Furthermore, UIOS correctly predicted high uncertainty scores, which would prompt the need for a manual check in the datasets of non-target categories retinal diseases, low-quality fundus images, and non-fundus images. UIOS provides a robust method for real-world screening of retinal anomalies. © 2023, CC BY.

关键词： Uncertainty analysis

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PWCLO-Net: Deep LiDAR odometry in 3D point clouds using hierarchical embedding mask optimization

arXiv

引用

arXiv 2020年

作者： Wang, Guangming Wu, Xinrui Liu, Zhe Wang, Hesheng Department of Automation Insititue of Medical Robotics Key Laboratory of System Controland Information Processing of Ministry of Education Shanghai Jiao Tong University Department of Computer Science and Technology University of Cambridge

A novel 3D point cloud learning model for deep LiDAR odometry, named PWCLO-Net, using hierarchical embedding mask optimization is proposed in this paper. In this model, the Pyramid, Warping, and Cost volume (PWC) structure for the LiDAR odometry task is built to refine the estimated pose in a coarse-to-fine approach hierarchically. An attentive cost volume is built to associate two point clouds and obtain embedding motion patterns. Then, a novel trainable embedding mask is proposed to weigh the local motion patterns of all points to regress the overall pose and filter outlier points. The estimated current pose is used to warp the first point cloud to bridge the distance to the second point cloud, and then the cost volume of the residual motion is built. At the same time, the embedding mask is optimized hierarchically from coarse to fine to obtain more accurate filtering information for pose refinement. The trainable pose warp-refinement process is iteratively used to make the pose estimation more robust for outliers. The superior performance and effectiveness of our LiDAR odometry model are demonstrated on KITTI odometry dataset. Our method outperforms all recent learning-based methods and outperforms the geometry-based approach, LOAM with mapping optimization, on most sequences of KITTI odometry *** source codes will be released on https://***/IRMVLab/PWCLONet. Copyright © 2020, The Authors. All rights reserved.

关键词： Iterative methods

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Risk-averse MPC via visual-inertial input and recurrent networks for online collision avoidance

arXiv

引用

arXiv 2020年

作者： Schperberg, Alexander Chen, Kenny Tsuei, Stephanie Jewett, Michael Hooks, Joshua Soatto, Stefano Mehta, Ankur Hong, Dennis The Robotics and Mechanisms Laboratory Department of Mechanical and Aerospace Engineering United States The Laboratory for Embedded Machines and Ubiquitous Robots Department of Electrical and Computer Engineering United States The UCLA Vision Lab Department of Computer Science United States The University of California Los Angeles Los AngelesCA90095 United States

In this paper, we propose an online path planning architecture that extends the model predictive control (MPC) formulation to consider future location uncertainties for safer navigation through cluttered environments. Our algorithm combines an object detection pipeline with a recurrent neural network (RNN) which infers the covariance of state estimates through each step of our MPC's finite time horizon. The RNN model is trained on a dataset that comprises of robot and landmark poses generated from camera images and inertial measurement unit (IMU) readings via a state-of-the-art visual-inertial odometry framework. To detect and extract object locations for avoidance, we use a custom-trained convolutional neural network model in conjunction with a feature extractor to retrieve 3D centroid and radii boundaries of nearby obstacles. The robustness of our methods is validated on complex quadruped robot dynamics and can be generally applied to most robotic platforms, demonstrating autonomous behaviors that can plan fast and collision-free paths towards a goal point. Copyright © 2020, The Authors. All rights reserved.

关键词： Model predictive control

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