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arXiv 2019年

作者： Klamt, Tobias Rodriguez, Diego Baccelliere, Lorenzo Chen, Xi Chiaradia, Domenico Cichon, Torben Gabardi, Maßimiliano Guria, Paolo Holmquist, Karl Kamedula, Malgorzata Karaoguz, Hakan Kashiri, Navvab Laurenzi, Arturo Lenz, Christian Leonardis, Daniele Hoffman, Enrico Mingo Muratore, Luca Pavlichenko, Dmytro Porcini, Francesco Ren, Zeyu Schilling, Fabian Schwarz, Max Solazzi, Maßimiliano Felsberg, Michael Frisoli, Antonio Gustmann, Michael Jensfelt, Patric Nordberg, Klas Roßmann, Jürgen Süß, Uwe Tsagarakis, Nikos G. Behnke, Sven Autonomous Intelligent Systems University of Bonn Germany Humanoids and Human-Centred Mechatronics Istituto Italiano di Tecnologia Genoa Italy Department of Robotics Perception and Learning KTH Royal Institute of Technology Stockholm Sweden PERCRO Laboratory TeCIP Institute Sant'Anna School of Advanced Studies Pisa Italy Institute for Man-Machine Interaction RWTH Aachen University Germany Computer Vision Laboratory Linköping University Sweden Lausanne Switzerland Kerntechnische Hilfsdienst GmbH Karlsruhe Germany School of Electrical and Electronic Engineering University of Manchester United Kingdom

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Parallel medical imaging for intelligent medical image analysis: Concepts, methods, and applications

arXiv

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arXiv 2019年

作者： Gou, Chao Shen, Tianyu Zheng, Wenbo Xue, Huadan Yu, Hui Ji, Qiang Jin, Zhengyu Wang, Fei-Yue School of Intelligent Systems Engineering Sun Yat-sen University Guangzhou510275 China The State Key Laboratory for Management and Control of Complex Systems Institute of Automation Chinese Academy of Sciences Beijing100190 China University of Chinese Academy of Sciences Beijing100049 China School of Software Engineering Xi’an Jiaotong University Xi’an710049 China Department of Radiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences Peking Union Medical College Beijing100730 China School of Creative Technologies University of Portsmouth PortsmouthPO1 2DJ United Kingdom Department of Electrical Computer and Systems Engineering Rensselaer Polytechnic Institute Qingdao Academy of Intelligent Industries Qingdao266000 China

Data-driven artificial intelligence technologies have made much progress in medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data, extracting medical domain knowledge, and explaining the diagnostic decision for medical image analysis. In this paper, we propose a data-knowledge-driven framework termed as Parallel Medical Imaging (PMI) for intelligent medical image analysis based on the methodology of interactive ACP-based parallel intelligence. In the PMI framework, computational experiments with predictive learning in a data-driven way are conducted to extract medical knowledge for diagnostic decision support. Artificial imaging systems are introduced to select and prescriptively generate medical image data in a knowledge-driven way to utilize medical domain knowledge. Through the closed-loop optimization based on parallel execution, our proposed PMI framework can boost the generalization ability and alleviate the limitation of medical interpretation for diagnostic decisions. Furthermore, we illustrate the preliminary implementation of PMI method through the case studies of mammogram analysis and skin lesion image analysis. Experimental results on several public medical image datasets demonstrate the effectiveness of proposed PMI. © 2019, CC BY.

关键词： Medical imaging

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Learn2Reg: comprehensive multi-task medical image registration challenge, dataset and evaluation in the era of deep learning

arXiv

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arXiv 2021年

作者： Hering, Alessa Hansen, Lasse Mok, Tony C.W. Chung, Albert C.S. Siebert, Hanna Häger, Stephanie Lange, Annkristin Kuckertz, Sven Heldmann, Stefan Shao, Wei Vesal, Sulaiman Rusu, Mirabela Sonn, Geoffrey Estienne, Théo Vakalopoulou, Maria Han, Luyi Huang, Yunzhi Yap, Pew-Thian Brudfors, Mikael Balbastre, Yaël Joutard, Samuel Modat, Marc Lifshitz, Gal Raviv, Dan Lv, Jinxin Li, Qiang Jaouen, Vincent Visvikis, Dimitris Fourcade, Constance Rubeaux, Mathieu Pan, Wentao Xu, Zhe Jian, Bailiang De Benetti, Francesca Wodzinski, Marek Gunnarsson, Niklas Sjölund, Jens Grzech, Daniel Qiu, Huaqi Li, Zeju Thorley, Alexander Duan, Jinming Großbröhmer, Christoph Hoopes, Andrew Reinertsen, Ingerid Xiao, Yiming Landman, Bennett Huo, Yuankai Murphy, Keelin Lessmann, Nikolas van Ginneken, Bram Dalca, Adrian V. Heinrich, Mattias P. Institute of Medical Informatics Universität zu Lübeck Ratzeburger Allee 160 Lübeck23562 Germany Fraunhofer MEVIS Institute for Digital Medicine Lübeck23562 Germany Department of Radiology and Nuclear Medicine Radboud University Medical Center GA Nijmegen6525 Netherlands The Institute of Medical Informatics Universität zu Lübeck Lübeck23562 Germany The Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong The Fraunhofer MEVIS Institute for Digital Medicine Lübeck23562 Germany The Department of Radiology Stanford University StanfordCA94305 United States The Department of Urology Stanford University StanfordCA94305 United States The Université Paris-Saclay CentraleSupélec Mathématiques et Informatique pour la Complexité et les Systèmes Inria Saclay Gif-sur-Yvette 91190 France Université Paris-Saclay Institut Gustave Roussy Inserm Radiothérapie Moléculaire et Innovation Thérapeutique Villejuif94800 France The Université Paris-Saclay CentraleSupélec Mathématiques et Informatique pour la Complexité et les Systèmes Inria Saclay Gif-sur-Yvette91190 France The Department of Radiology and Nuclear Medicine Radboud University Medical Center Nijmegen6525 GA Netherlands The School of Automation Nanjing University of Information Science and Technology Nanjing210044 China The School of Biomedical Engineering and Imaging Sciences King’s College London London United Kingdom The Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital United States Harvard Medical School Boston United States The King’s College London United Kingdom The Tel Aviv University The Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology Hubei Wuhan430074 China MoE Key Laboratory for Biomedical Photonics Collaborative Innovation Center for Biomedical Engineering School of Engineering Sciences Huazhong University of Sci

Image registration is a fundamental medical image analysis task, and a wide variety of approaches have been proposed. However, only a few studies have comprehensively compared medical image registration approaches on a wide range of clinically relevant tasks. This limits the development of registration methods, the adoption of research advances into practice, and a fair benchmark across competing approaches. The Learn2Reg challenge addresses these limitations by providing a multi-task medical image registration data set for comprehensive characterisation of deformable registration algorithms. A continuous evaluation will be possible at https://***. Learn2Reg covers a wide range of anatomies (brain, abdomen, and thorax), modalities (ultrasound, CT, MR), availability of annotations, as well as intra- and inter-patient registration evaluation. We established an easily accessible framework for training and validation of 3D registration methods, which enabled the compilation of results of over 65 individual method submissions from more than 20 unique teams. We used a complementary set of metrics, including robustness, accuracy, plausibility, and runtime, enabling unique insight into the current state-of-the-art of medical image registration. This paper describes datasets, tasks, evaluation methods and results of the challenge, as well as results of further analysis of transferability to new datasets, the importance of label supervision, and resulting bias. While no single approach worked best across all tasks, many methodological aspects could be identified that push the performance of medical image registration to new state-of-the-art performance. Furthermore, we demystified the common belief that conventional registration methods have to be much slower than deep-learning-based methods. © 2021, CC BY.

关键词： Image registration

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The dynamic interactions between chemotherapy drugs and plasmid DNA investigated by atomic force microscopy

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Science China Materials 2017年第3期60卷 269-278页

作者：李密刘连庆肖秀斌席宁王越超 State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences Department of Lymphoma Affiliated Hospital of Military Medical Academy of Sciences Department of Electrical and Computer Engineering Michigan State University

The advent of atomic force microscopy （AFM） provides a powerful tool for imaging individual DNA molecules. Chemotherapy drugs are often related to DNAs. Though many specific drug-DNA interactions have been observed by AFM, knowledge about the dynamic interactions between chemotherapy drugs and plasmid DNAs is still scarce. In this work, AFM was applied to investigate the nanoscale interactions between plasmid DNAs and two commercial chemotherapy drugs （methotrexate and cisplatin）. Plasmid DNAs were immobilized on mica which was coated by silanes in advance. AFM imaging distinctly revealed the dynamic changes of single plasmid DNAs after the stimulation of methotrexate and cisplatin. Geometric features of plasmid DNAs were extracted from AFM images and the statistical results showed that the geometric features of plasmid DNAs changed significantly after the stimulation of drugs. This research provides a novel idea to study the actions of chemotherapy drugs against plasmid DNAs at the single-molecule level.

关键词： atomic force microscopy plasmid DNA drug methotrexate cisplatin

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Multi-Scale Recurrent Neural Network for Sound Event Detection

Multi-Scale Recurrent Neural Network for Sound Event Detecti...

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IEEE International Conference on Acoustics, Speech and Signal Processing

作者： Rui Lu Zhiyao Duan Changshui Zhang Department of Automation Tsinghua University State Key Lab of Intelligent Technologies and Systems Tsinghua National Laboratory for Information Science and Technology (TNList) Beijing P.R.China Department of Electrical and Computer Engineering University of Rochester Rochester NY USA

ISBN: (纸本)9781538646595

Sound event detection (SED) in real life is an interesting but challenging task due to the polyphonic and long-term dependent nature of sound events. Recently, multi-label recurrent neural networks (RNNs) have shown promises. However, even equipped with long short-term memory (LSTM) or gated recurrent unit (GRU) cells, RNNs are still limited to model the long-term dependency. In this paper, we propose a multiscale RNN to address this issue. By integrating information from different time resolutions, we can better capture both the fine-grained and long-term dependencies of sound events. We experiment on the development sets of Task3 of DCASE2016 and DCASE2017. Compared to our previously proposed single-scale RNN that won the third place among the 13 teams in Task3 of DCASE2017, the proposed multiscale model achieves statistically significantly better performance on the development datasets of both DECASE2016 and DCASE2017.

关键词： Multi-scale model deep learning recurrent neural network sound event detection recurrent neural nets multiscale models Event detection Machine Learning SOUND Vibration Hearing temporal resolution

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Sensorless nonlinear control of fed-batch Escherichia coli cultivation bioprocess using the state-dependent approach 12th

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12th Portuguese Conference on Automatic Control, CONTROLO 2016

作者： Iratni, Abdelhamid Araújo, Rui Rastegar, Saeid Mostefai, Mohammed Faculty of Science and Technology Electrical Engineering Department University of Bordj Bou Arreridj El Anasser Algeria Department of Electrical and Computer Engineering Institute for Systems and Robotics University of Coimbra Coimbra Portugal Automatic Control Laboratory of Setif Electrical Engineering Department Faculty of Technology University of Setif1 Sétif Algeria

ISBN: (纸本)9783319436708

The cultivation of Escherichia coli bacteria is widely used by geneticists and biopharmaceuticals to produce medicines and vaccines. In such industries, Bioprocesses are known by their harsh environment and very expensive physical sensors. This paper deals with nonlinear estimation and control of fed-batch Escherichia coli bioprocess. Enhancing the process performance and maximizing its efficiency by optimizing the control of Escherichia coli cultures depends on the availability of appropriate online sensors for the main culture components. In this study, an innovative method for nonlinear estimation and control of bioprocesses is designed and assessed. The new algorithm for control and estimation of Escherichia coli bioprocess states, based on the State-Dependent Riccati Equation technique, is validated by numerical simulation. The results obtained clearly demonstrate the effectiveness of the proposed technique for Biosystems in measuring, monitoring, and control of their natural nonlinear dynamics. © Springer International Publishing Switzerland 2017.

关键词： Extended Kalman filters

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Machine discovery of partial differential equations from spatiotemporal data

arXiv

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arXiv 2019年

作者： Yuan, Ye Li, Junlin Li, Liang Jiang, Frank Tang, Xiuchuan Zhang, Fumin Liu, Sheng Goncalves, Jorge Voss, Henning U. Li, Xiuting Kurths, Jürgen Ding, Han School of Artificial Intelligence and Automation State Key Laboratory of Digital Manufacturing Equipments and Technology Huazhong University of Science and Technology Wuhan430074 China School of Artificial Intelligence and Automation Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology Wuhan430074 China School of Electrical Engineering and Computer Science KTH Royal Institute of Technology Stockholm11428 Sweden School of Mechanical Science and Engineering Huazhong University of Science and Technology Wuhan430074 China School of Electrical and Computer Engineering Georgia Institute of Technology Atlanta30332 United States School of Power and Mechanical Engineering Wuhan University Wuhan430074 China Department of Engineering University of Cambridge CambridgeCB2 1PZ United Kingdom Luxembourg Centre for Systems Biomedicine University of Luxembourg BelvauxL-4367 Luxembourg Citigroup Biomedical Imaging Center Weill Cornell Medical College New York10021 United States Research Domain IV - Transdisciplinary Concepts & Methods Potsdam Institute for Climate Impact Research Potsdam14473 Germany School of Mechanical Science and Engineering State Key Laboratory of Digital Manufacturing Equipments and Technology Huazhong University of Science and Technology Wuhan430074 China

The study presents a general framework for discovering underlying Partial Differential Equations (PDEs) using measured spatiotemporal data. The method, called Sparse Spatiotemporal System Discovery (S3d), decides which physical terms are necessary and which can be removed (because they are physically negligible in the sense that they do not affect the dynamics too much) from a pool of candidate functions. The method is built on the recent development of Sparse Bayesian Learning;which enforces the sparsity in the to-be-identified PDEs, and therefore can balance the model complexity and fitting error with theoretical guarantees. Without leveraging prior knowledge or assumptions in the discovery process, we use an automated approach to discover ten types of PDEs, including the famous Navier-Stokes and sine-Gordon equations, from simulation data alone. Moreover, we demonstrate our data-driven discovery process with the Complex Ginzburg-Landau Equation (CGLE) using data measured from a traveling-wave convection experiment. Our machine discovery approach presents solutions that has the potential to inspire, support and assist physicists for the establishment of physical laws from measured spatiotemporal data, especially in notorious fields that are often too complex to allow a straightforward establishment of physical law, such as biophysics, fluid dynamics, neuroscience or nonlinear optics. Copyright © 2019, The Authors. All rights reserved.

关键词： Nonlinear optics

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Robust ADRC for Nonlinear Time-varying System with Uncertainties 6

Robust ADRC for Nonlinear Time-varying System with Uncertain...

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2017 IEEE 6th Data Driven Control and Learning systems Conference (DDCLS’17)

作者： Xiangyang Li Wei Ai Zhiqiang Gao Senping Tian Key Laboratory of Autonomous Systems and Networked Control Ministry of Education School of Automation Science and Engineering South China University of Technology IEEE Center for Advanced Control Technologies Department of Electrical and Computer EngineeringCleveland State University

ISBN: (纸本)9781509054626

Active disturbance rejection control(ADRC) exemplifies the spirit of the data-driven control(DDC) design strategy and shows much promise in obtaining consistent applications in industrial control systems with uncertainties, without the premise that the detailed mathematical model of the controlled system is given. Instead, it is shown that the information needed for the control system to work at high level of effectiveness can be extracted from the input-output data by the use of the extended state observer(ESO). On the other hand, it is shown in this paper that the robustness of ADRC depends on the effectiveness of ESO. Furthermore, taking advantage of the rich body of knowledge in the existing field of robust control, the estimation error in ESO is analysed and, for the purpose of improved robustness, a unique nonlinear component is added to the conventional ADRC law. The modified ADRC which is a kind of robust ADRC law is validated in simulation for a nonlinear time-varying system with parametric and functional uncertainties. It is shown that the proposed robust ADRC law provides more effective tracking performance than the conventional ADRC when the bandwidth of ESO is not wide enough.

关键词： Active Disturbance Rejection Control(ADRC) Robust Control Extended State Observer(ESO) Nonlinear Time-varying System

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Correction to: Editorial

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International Journal of Social robotics 2019年第6期15卷 1077-1077页

作者： Ge, Shuzhi Sam Wykowska, Agnieszka Khatib, Oussama Social Robotics Laboratory Smart Systems Institute Department of Electrical and Computer Engineering The National University of Singapore Singapore Singapore Institute for Future (IFF) Qingdao University Qingdao China Centre for Robotics UESTC Chengdu China Social Cognition in Human-Robot Interaction Istituto Italiano di Tecnologia Genoa Italy Artificial Intelligence Laboratory Department of Computer Science Stanford University Stanford USA

This is to inform you that the following sentence was inadvertently omitted from the final version

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Relaxed conditions for uniform complete observability and controllability of LTV systems with bounded realizations

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IFAC-PapersOnLine 2017年第1期50卷 3598-3605页

作者： Batista P. Petit N. Silvestre C. Oliveira P. Institute for Systems and Robotics Laboratory for Robotics and Engineering Systems Instituto Superior Técnico Universidade de Lisboa Portugal MINES ParisTech PSL Research University CAS – Centre automatique et systémes 60 bd St Michel Paris 75272 France Department of Electrical and Computer Engineering Faculty of Science and Technology of the University of Macau Macau Department of Mechanical Engineering Instituto Superior Técnico Universidade de Lisboa Portugal

Uniform complete observability and controllability are key concepts for the design of state observers and controllers for linear time-varying systems. While the definitions of these properties are simple, it is more often that not very difficult to show they hold for a particular system. This paper presents alternative simpler sufficient conditions. Examples are shown that illustrate the improvement over previous results, the fact that the new conditions are not necessary, and a practical application. © 2017

关键词： linear time-varying systems uniform complete controllability uniform complete observability

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