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arXiv 2019年

作者： Hüser, Matthias Kündig, Adrian Karlen, Walter De Luca, Valeria Jaggi, Martin Biomedical Informatics Group Department of Computer Science ETH Zürich Universitätstrasse 6 Zürich8092 Switzerland Mobile Health Systems Lab Institute of Robotics and Intelligent Systems Department of Health Sciences and Technology ETH Zürich Zürich8008 Switzerland Department of Information Technology and Electrical Engineering ETH Zürich Zürich8092 Switzerland Machine Learning & Optimization Lab EPFL Lausanne1015 Switzerland

Objective: Acute intracranial hypertension is an important risk factor of secondary brain damage after traumatic brain injury. Hypertensive episodes are often diagnosed reactively, leading to late detection and lost time for intervention planning. A pro-active approach that predicts critical events several hours ahead of time could assist in directing attention to patients at risk. Approach: We developed a prediction framework that forecasts onsets of acute intracranial hypertension in the next 8 hours. It jointly uses cerebral auto-regulation indices, spectral energies and morphological pulse metrics to describe the neurological state of the patient. One-minute base windows were compressed by computing signal metrics, and then stored in a multi-scale history, from which physiological features were derived. Main results: Our model predicted events up to 8 hours in advance with alarm recall rates of 90% at a precision of 30.3% in the MIMIC-III waveform database, improving upon two baselines from the literature. We found that features derived from high-frequency waveforms substantially improved the prediction performance over simple statistical summaries of low-frequency time serie1s, and each of the three feature classes contributed to the performance gain. The inclusion of long-term history up to 8 hours was especially important. Significance: Our results highlight the importance of information contained in high-frequency waveforms in the neurological intensive care unit. They could motivate future studies on pre-hypertensive patterns and the design of new alarm algorithms for critical events in the injured brain. Copyright © 2019, The Authors. All rights reserved.

关键词： Morphology

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Gait Phase Classification Based on sEMG Signals Using Long Short-Term Memory for Lower Limb Exoskeleton Robot

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IOP Conference Series: Materials Science and engineering 2020年第1期853卷

作者： Ye Yuan Ziming Guo Can Wang Shengcai Duan Lufeng Zhang Xinyu Wu Guangdong Provincial Key Lab of Robotics and Intelligent System Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences CAS Key Laboratory of Human-Machine Intelligence-Synergic Systems Shenzhen Institutes of Advanced Technology Chongqing Key Laboratory of Nonlinear Circuits and Intelligent Information Processing College of Electronic and Information Engineering Southwest University.

In this work, we present a Long Short-Term Memory Model (LSTMM) for gait phase classification based on sEMG signals to control the lower limb exoskeleton robot which can recognize 2 phases (Stand and Swing) of leg phases between the foot and ground. This model only needs four sEMG signals to control the lower limb exoskeleton robot helping the hemiplegia patient walking. Compared with the existing methods, the proposed model not only avoids the complex sensor systems but also enhances the accuracy of gait phase classification. The experimental results first verify the availability of sEMG data acquisition system on the lower limb exoskeleton robot made by the Shenzhen Institutes of Advanced Technologies (SIAT) by quantify the system with gold standard optoelectronic system Vicon, then show that the proposed LSTMM is significantly higher on prediction accuracy and has better robustness for gait phase classification to control the lower limb exoskeleton robot with different speeds. Finally, the maximum accuracy of LSTMM on the gait phase classification is 97.89%.

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Deep learning methods for automatic evaluation of delayed enhancement-MRI. The results of the EMIDEC challenge

arXiv

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arXiv 2021年

作者： Lalande, Alain Chen, Zhihao Pommier, Thibaut Decourselle, Thomas Qayyum, Abdul Salomon, Michel Ginhac, Dominique Skandarani, Youssef Boucher, Arnaud Brahim, Khawla de Bruijne, Marleen Camarasa, Robin Correia, Teresa M. Feng, Xue Girum, Kibrom B. Hennemuth, Anja Huellebrand, Markus Hussain, Raabid Ivantsits, Matthias Ma, Jun Meyer, Craig Sharma, Rishabh Shi, Jixi Tsekos, Nikolaos V. Varela, Marta Wang, Xiyue Yang, Sen Zhang, Hannu Zhang, Yichi Zhou, Yuncheng Zhuang, Xiahai Couturier, Raphael Meriaudeau, Fabrice ImViA laboratory University of Burgundy Dijon France MRI department University Hospital of Dijon Dijon France Femto-ST laboratory University of Franche-Comté Belfort France Cardiology department University Hospital of Dijon Dijon France CASIS Company Quetigny France National Engineering School of Sousse University of Sousse Sousse Tunisia LASEE laboratory National Engineering School of Monastir University of Monastir Monastir Tunisia Biomedical Imaging Group Rotterdam Erasmus MC Rotterdam Netherlands Department of Radiology and Nuclear Medicine Erasmus MC Rotterdam Netherlands Department of Computer Science University of Copenhagen Copenhagen Denmark Centre of Marine Sciences University of Algarve Faro Portugal School of Biomedical Engineering and Imaging Sciences King’s College London London United Kingdom Department of Biomedical Engineering University of Virginia Charlottesville United States Charité – Universitätsmedizin Berlin Berlin Germany Fraunhofer MEVIS Bremen Germany German Centre for Cardiovascular Research Berlin Germany Department of Mathematics Nanjing University of Science and Technology Nanjing China Data Analysis and Intelligent Systems Lab Department of Computer Science University of Houston Houston United States Medical Robotics and Imaging Lab Department of Computer Science University of Houston Houston United States National Heart and Lung Institute Imperial College London London United Kingdom College of Computer Science Sichuan University Chengdu China College of Biomedical Engineering Sichuan University Chengdu China School of Biological Science and Medical Engineering Beihang University Beijing China School of Data Science Fudan University Shanghai China

A key factor for assessing the state of the heart after myocardial infarction (MI) is to measure whether the myocardium segment is viable after reperfusion or revascularization therapy. Delayed enhancement-MRI or DE-MRI, which is performed several minutes after injection of the contrast agent, provides high contrast between viable and nonviable myocardium and is therefore a method of choice to evaluate the extent of MI. To automatically assess myocardial status, the results of the EMIDEC challenge that focused on this task are presented in this paper. The challenge’s main objectives were twofold. First, to evaluate if deep learning methods can distinguish between normal and pathological cases. Second, to automatically calculate the extent of myocardial infarction. The publicly available database consists of 150 exams divided into 50 cases with normal MRI after injection of a contrast agent and 100 cases with myocardial infarction (and then with a hyperenhanced area on DE-MRI), whatever their inclusion in the cardiac emergency department. Along with MRI, clinical characteristics are also provided. The obtained results issued from several works show that the automatic classification of an exam is a reachable task (the best method providing an accuracy of 0.92), and the automatic segmentation of the myocardium is possible. However, the segmentation of the diseased area needs to be improved, mainly due to the small size of these areas and the lack of contrast with the surrounding structures. © 2021, CC BY-NC-SA.

关键词： Cardiology

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Real-time perception meets reactive motion generation

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IEEE robotics and Automation Letters 2018年第3期3卷 1864-1871页

作者： Kappler, Daniel Meier, Franziska Issac, Jan Mainprice, Jim Cifuentes, Cristina Garcia Wuthrich, Manuel Berenz, Vincent Schaal, Stefan Ratliff, Nathan Bohg, Jeannette Autonomous Motion Department MPI for Intelligent Systems Stuttgart70569 Germany Lula Robotics Inc. SeattleWA98102 United States CLMC Lab University of Southern California Los AngelesCA90007 United States Department of Computer Science and Engineering University of Washington SeattleWA98195 United States University of Stuttgart Stuttgart70174 Germany Department of Computer Science Stanford University StanfordCA94305 United States

We address the challenging problem of robotic grasping and manipulation in the presence of uncertainty. This uncertainty is due to noisy sensing, inaccurate models, and hard-to-predict environment dynamics. We quantify the importance of continuous, real-time perception and its tight integration with reactive motion generation methods in dynamic manipulation scenarios. We compare three different systems that are instantiations of the most common architectures in the field: 1) a traditional sense-plan-act approach that is still widely used;2) a myopic controller that only reacts to local environment dynamics;and 3) a reactive planner that integrates feedback control and motion optimization. All architectures rely on the same components for real-time perception and reactive motion generation to allow a quantitative evaluation. We extensively evaluate the systems on a real robotic platform in four scenarios that exhibit either a challenging workspace geometry or a dynamic environment. We quantify the robustness and accuracy that is due to integrating real-time feedback at different time scales in a reactive motion generation system. We also report on the lessons learned for system building. © 2016 IEEE.

关键词： Memory architecture

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Understanding metric-related pitfalls in image analysis validation

arXiv

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arXiv 2023年

作者： Reinke, Annika Tizabi, Minu D. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Kavur, A. Emre Rädsch, Tim Sudre, Carole H. Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Buettner, Florian Cardoso, M. Jorge Cheplygina, Veronika Chen, Jianxu Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kleesiek, Jens Kofler, Florian Kooi, Thijs Kopp-Schneider, Annette Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Riegler, Michael A. Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. van Calster, Ben Varoquaux, Gaël Yaniv, Ziv R. Jäger, Paul F. Maier-Hein, Lena Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany NCT Heidelberg A Partnership Between DKFZ University Medical Center Heidelberg Germany Heidelberg Division of Medical Image Computing Germany Heidelberg Division of Intelligent Medical Systems Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montreal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Leuven Belgium partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany and Frankfurt Cancer Insititute Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for Statistics in Medicine University of Oxford Oxford United Kingdom Center for Biomedical In

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately. While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. While focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation. © 2023, CC BY.

关键词： Computer vision

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Quantification of Extent of Muscle-skin Shifting by Traversal sEMG Analysis Using High-density sEMG Sensor

Quantification of Extent of Muscle-skin Shifting by Traversa...

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IEEE International Conference on Cyborg and Bionic systems (CBS)

作者： Shotaro Okajima Eduardo Iáñez Hiroshi Yamasaki Álvaro Costa García Fady S. Alnajjar Noriaki Hattori Shingo Shimoda Man-Machine Collaboration Research Team Robotics Project Baton Zone Program Science Technology and Innovation Hub RIKEN Nagoya Japan Brain-Machine Interface Systems Lab Miguel Hernández University of Elche Spain Intelligent Behavior Control Unit BTCC CBS RIKEN Nagoya Japan College of IT (CIT) UAE University (UAEU) Global Center for Medical Engineering and Informatics Osaka University

ISBN: (数字)9781728150734

ISBN: (纸本)9781728150741

Surface electromyography(sEMG) measurement has been an essential approach to analyze human behaviors because we can generally consider that sEMG signals represent the muscle activities as the final output of our nerve system. One of the most serious problems for considering sEMG signal as the muscle activity is the shift of the relative position between muscles and skin depending on a posture. The motion of forearm rotation is the prominent example of muscle-skin shifting depending on postural changes. The sEMG signal from a sensor may represent the different muscle activity when the muscle-skin shifting is happened. In this study, we discuss a method to quantify the muscle-skin shift from the sEMG signals in response to the postural changes. We use the high density sEMG sensor that is possible to measure sEMG signal as the potential map. We proposed the computation algorithm to quantify the amount of muscle-skin shifting based on the change of the sEMG signals in response to the postural changes. We conducted the experiments of wrist extension motions under three different forearm postures: forearm pronation, natural posture and forearm supination. Experimental results from three healthy subjects show that we can quantify the extent of muscle-skin shifting as an angle by using proposed algorithm.

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Human intention estimation based on hidden Markov model motion validation for safe flexible robotized warehouses

arXiv

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arXiv 2018年

作者： Petković, Tomislav Puljiz, David Marković, Ivan Hein, Björn University of Zagreb Faculty of Electrical Engineering and Computing Department of Control and Computer Engineering Laboratory for Autonomous Systems and Mobile Robotics Unska 3 ZagrebHR-10000 Croatia Karlsruhe Institute of Technology Institute for Anthropomatics and Robotics Intelligent Process Automation and Robotics Lab Kaiserstraße 12 Deutschland KarlsruheDE-76131

With the substantial growth of logistics businesses the need for larger warehouses and their automation arises, thus using robots as assistants to human workers is becoming a priority. In order to operate efficiently and safely, robot assistants or the supervising system should recognize human intentions in real-time. Theory of mind (ToM) is an intuitive human conception of other humans' mental state, i.e., beliefs and desires, and how they cause behavior. In this paper we propose a ToM based human intention estimation algorithm for flexible robotized warehouses. We observe human's, i.e., worker's motion and validate it with respect to the goal locations using generalized Voronoi diagram based path planning. These observations are then processed by the proposed hidden Markov model framework which estimates worker intentions in an online manner, capable of handling changing environments. To test the proposed intention estimation we ran experiments in a real-world laboratory warehouse with a worker wearing Microsoft Hololens augmented reality glasses. Furthermore, in order to demonstrate the scalability of the approach to larger warehouses, we propose to use virtual reality digital warehouse twins in order to realistically simulate worker behavior. We conducted intention estimation experiments in the larger warehouse digital twin with up to 24 running robots. We demonstrate that the proposed framework estimates warehouse worker intentions precisely and in the end we discuss the experimental results. Copyright © 2018, The Authors. All rights reserved.

关键词： Virtual reality

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An overview of perception methods for horticultural robots: From pollination to harvest

arXiv

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arXiv 2018年

作者： Ahn, Ho Seok Dayoub, Feras Popović, Marija MacDonald, Bruce A. Siegwart, Roland Sa, Inkyu Department of Electrical and Computer Engineering CARES University of Auckland 368 Khyber Pass Rd Newmarket Auckland1023 New Zealand Department of Mechanical and Process Engineering Institute of Robotics and Intelligent Systems Autonomous Systems Lab. ETH Zurich Switzerland

Horticultural enterprises are becoming more sophisticated as the range of the crops they target expands. Requirements for enhanced efficiency and productivity have driven the demand for automating on-field operations. However, various problems remain yet to be solved for their reliable, safe deployment in real-world scenarios. This paper examines major research trends and current challenges in horticultural robotics. Specifically, our work focuses on sensing and perception in the three main horticultural procedures: Pollination, yield estimation, and harvesting. For each task, we expose major issues arising from the unstructured, cluttered, and rugged nature of field environments, including variable lighting conditions and difficulties in fruit-specific detection, and highlight promising contemporary studies. Based on our survey, we address new perspectives and discuss future development trends. Copyright © 2018, The Authors. All rights reserved.

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Metrics Reloaded: Recommendations for image analysis validation

arXiv

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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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Outer-linearization-based optimization algorithm for decentralized control design in flexure-linked H-gantry

Outer-linearization-based optimization algorithm for decentr...

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2018 IEEE/ASME International Conference on Advanced intelligent Mechatronics, AIM 2018

作者： Ma, Jun Chen, Si-Lu Liang, Wenyu Li, Xiaocong Teo, Chek Sing Tay, Arthur Mamun, Abdullah Al Tan, Kok Kiong SIMTech-NUS Joint Lab. on Precision Motion Systems Department of Electrical and Computer Engineering National University of Singapore Singapore117582 Singapore Department of Electrical and Computer Engineering National Universit of Singapore Singapore117583 Singapore Mechatronics Group Singapore Institute of Manufacturing Technology Singapore138634 Singapore Zhejiang Provincial Key Laboratory of Robotics and Intelligent Manufacturing Equipment Technology Ningbo Institute of Industrial Technology Chinese Academy of Sciences Ningbo Zhejiang315121 China

ISBN: (纸本)9781538618547

The dual-drive H-gantry (DHG) is widely used for high-speed high-precision Cartesian motion control applications. Compared with the rigid-linked gantry design, the flexure-linked design is able to prevent the damage of the cross-arm because a small degree of rotation angle is allowed. Nevertheless, the flexure-linked design possibly induces the resonance of the gantry because of the chattering of control signals. To maintain the precision tracking of two carriages and minimize the chattering of control efforts, we aim to seek the most suitable flexure joints among the available ones and optimize the decentralized feedback controller parameters under parametric uncertainties. The mechatronic design problem is formulated as an H2 guaranteed cost control problem. All the stabilizing feedback controller gains are parameterized over a convex set, from here, numerical procedures are developed to obtain the global optimum by means of an outer-linearization-based optimization algorithm. Experiments are carried out and the results successfully validate the optimality and the robustness of the proposed design approach. © 2018 IEEE.

关键词： Feedback control

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