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第六届国际骨质疏松及骨矿盐疾病学术会议

作者： John A Shepherd Serghei Malkov Kathleen Peters Jane Cauley Steve Cummings Tamara Harris Rachel Murphy Suzanne Satterfield Marjolien Visser Joseph Wilson Joseph Zmuda Peggy Cawthon Department of Radiology & Biomedical Imaging University of California San FranciscoUSA UC Berkeley-UCSF Graduate Program in Bioengineering California Pacific Medical Center Department of Epidemiology Graduate School of Public HealthUniversity of PittsburghPittsburghPennsylvaniaUSA UC Berkeley-UCSF Graduate Program in Bioengineering San FranciscoCA USA

Objective We aimto determine the utility of quantifying DXA-derived surrogates of CT measures including thigh cross-sectional muscle area(CSA) and muscle attenuation. Methods We used a retrospective case-cohort study design using data from the HealthAging and Body Composition(HealthABC) *** were 111 participants that had a hip fracture during the 8.7-year study period.A cohortof 212 non-fracture participants wasrandomly selected

关键词： DXA Appendicular DXA BMC and Lean Mass Strongly Associated to Hip Fracture Risk BMC

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Association of body shape and fracture risk

Association of body shape and fracture risk

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第六届国际骨质疏松及骨矿盐疾病学术会议

作者： Bo Fan Joseph P Wilson John A Shepherd Department of Radiology & Biomedical Imaging University of California San FranciscoUSA Department of Radiology & Biomedical Imaging University of California San FranciscoUSA UC Berkeley-UCSF Graduate Program in BioengineeringSan FranciscoCA US

＜正＞Objective:To examine theindependent association ofbody shape（total volume,trunk volume,and trunk to leg volume ratio）tofracture risk. Methods:We performed a cross-sectional study of the NHANES 1999-2004 survey data downloaded from the study *** individualshad both a valid dual-energy Xray absorptiometry（DXA） scan and known fracture status. The body shape measureswere derived using DXA whole

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31st Annual Meeting and Associated programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016

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J Immunother Cancer 2016年第SUPPL 1期4卷 1-1页

作者： Andreas Lundqvist Vincent van Hoef Xiaonan Zhang Erik Wennerberg Julie Lorent Kristina Witt Laia Masvidal sanz Shuo Liang Shannon Murray Ola Larsson Rolf Kiessling Yumeng Mao John-William Sidhom Catherine A. Bessell Jonathan Havel Jonathan Schneck Timothy A. Chan Eliot Sachsenmeier David Woods Anders Berglund Rupal Ramakrishnan Andressa Sodre Jeffrey Weber Roberta Zappasodi Yanyun Li Jingjing Qi Philip Wong Cynthia Sirard Michael Postow Walter Newman Henry Koon Vamsidhar Velcheti Margaret K. Callahan Jedd D. Wolchok Taha Merghoub Lawrence G. Lum Minsig Choi Archana Thakur Abhinav Deol Gregory Dyson Anthony Shields Cara Haymaker Marc Uemura Ravi Murthy Marihella James Daqing Wang Julie Brevard Catherine Monaghan Suzanne Swann James Geib Mark Cornfeld Srinivas Chunduru Sudhir Agrawal Cassian Yee Jennifer Wargo Sapna P. Patel Rodabe Amaria Hussein Tawbi Isabella Glitza Scott Woodman Wen-Jen Hwu Michael A. Davies Patrick Hwu Willem W. Overwijk Chantale Bernatchez Adi Diab Erminia Massarelli Neil H. Segal Vincent Ribrag Ignacio Melero Tara C. Gangadhar Walter Urba Dirk Schadendorf Robert L. Ferris Roch Houot Franck Morschhauser Theodore Logan Jason J. Luke William Sharfman Fabrice Barlesi Patrick A. Ott Laura Mansi Shivaani Kummar Gilles Salles Cecilia Carpio Roland Meier Suba Krishnan Dan McDonald Matthew Maurer Xuemin Gu Jaclyn Neely Satyendra Suryawanshi Ronald Levy Nikhil Khushalani Jennifer Wu Jinyu Zhang Fahmin Basher Mark Rubinstein Mark Bucsek Guanxi Qiao Cameron MacDonald Bonnie Hylander Elizabeth Repasky Shilpak Chatterjee Anusara Daenthanasanmak Paramita Chakraborty Kyle Toth Megan Meek Elizabeth Garrett-Mayer Michael Nishimura Chrystal Paulos Craig Beeson Xuezhong Yu Shikhar Mehrotra Fei Zhao Kathy Evans Christine Xiao Alisha Holtzhausen Brent A. Hanks Nicole Scharping Ashley V. Menk Rebecca Moreci Ryan Whetstone Rebekah Dadey Simon Watkins Robert Ferris Greg M. Delgoffe Jonathan Peled Sean Devlin Anna Staffas Melissa Lumish Kori Porosnicu Rodriguez Katya Ahr Miguel Perales Sergio Giralt Ying Taur Eric Pam Karolinska Institutet Stockholm Stockholms Lan Sweden Weill Cornell Medical College New York NY USA Nova Southeastern University Cell Therapy Institute Fort Lauderdale FL USA Johns Hopkins University School of Medicine Baltimore MD USA Immunology Program Johns Hopkins University School of Medicine Columbia MD USA Memorial Sloan Kettering Cancer Center New York NY USA Johns Hopkins Medical Institute Baltimore MD USA University of Rochester Monrovia MD USA NYU Langone Medical Center New York NY USA H. Lee Moffitt Cancer Center Tampa FL USA Ludwig Collaborative Laboratory Memorial Sloan Kettering Cancer Center New York NY USA Immune Monitoring Core Facility Memorial Sloan Kettering Cancer Center New York NY USA Leap Therapeutics Cambridge MA USA Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA Case Western Reserve University Cleveland OH USA Cleveland Clinic Main Campus Cleveland OH USA University of Virginia Cancer Center Charlottesville VA USA Stony Brook University Medical Center Stony Brook NY USA Karmanos Cancer Institute Detroit MI USA University of Texas MD Anderson Cancer Center Houston TX USA Idera Pharmaceuticals Inc. Cambridge MA USA Institut Gustave Roussy Villejuif Ile-de-France France Center for Applied Medical Research (CIMA) University of Navarra Pamplona Navarra Spain University of Pennsylvania Philadelphia PA USA Earle A. Chiles Research Institute Providence Cancer Center Portland OR USA Universitätsklinikum Essen Essen Nordrhein-Westfalen Germany University of Pittsburgh Pittsburgh PA USA CHU Rennes Service Hématologie Clinique and INSERM 0203 Unité d’Investigation Clinique Rennes Bretagne France Centre Hospitalier Régional Universitaire de Lille Lille Nord-Pas-de-Calais France Simon Cancer Center Indiana University Indianapolis IN USA University of Chicago School of Medicine Chicago IL USA Johns Hopkins University School of Medicine Lutherville MD USA Multidisciplinary Oncology and Therapeuti

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ESICM LIVES 2016: part two

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Intensive Care Medicine Experimental 2016年第1期4卷 205-404页

作者： S. Sivakumar F. S. Taccone K. A. Desai C. Lazaridis M. Skarzynski M. Sekhon W. Henderson D. Griesdale L. Chapple A. Deane L. Williams R. Strickland K. Lange D. Heyland M. Chapman M. J. Rowland P. Garry J. Westbrook R. Corkill C. A. Antoniades K. T. Pattinson G. Fatania A. J. Strong R. B. Myers C. M. Jermaine C. S. Robertson C. G. Rusin J. Hofmeijer L. Sondag M. C. Tjepkema-Cloostermans A. Beishuizen F. H. Bosch M. J. A. M. van Putten L. Carteron C. Patet D. Solari M. Oddo M. A. Ali C. Dias R. Almeida A. Vaz-Ferreira J. Silva E. Monteiro A. Cerejo A. P. Rocha A. A. Elsayed A. M. Abougabal B. N. Beshey K. M. Alzahaby S. Pozzebon A. Blandino Ortiz S. Cristallini O. Lheureux A. Brasseur J. L. Vincent J. Creteur M. Hravnak K. Yousef Y. Chang E. Crago R. M. Friedlander S. A. Abdelmonem S. A. Tahon T. A. Helmy H. S. Meligy F. Puig I. Dunn-Siegrist J. Pugin S. Gupta D. Govil S. Srinivasan S. J. Patel J. K. N A. Gupta D. S. Tomar M. Shafi R. Harne D. P. Arora N. Talwar S. Mazumdar E. E. Papakrivou D. Makris E. Manoulakas B. Tsolaki B. Karadodas E. Zakynthinos I. Palacios Garcia A. Diaz Martin V. sanchez Encinares M. Pachón Ibañez J. Garnacho Montero G. Labrador T. Cebrero Cangueiro V. Poulose J. Koh J. W. Kam H. Yeter A. Kara O. Aktepe A. Topeli I. Tsolakoglou G. Intas P. Stergiannis A. A. Kolaros E. Chalari E. Athanasiadou A. Martika G. Fildisis V. Faivre C. Mengelle B. Favier D. Payen A. Poppe M. S. Winkler E. Mudersbach J. Schreiber M. L. Wruck E. Schwedhelm S. Kluge C. Zöllner T. Tavladaki A. M. Spanaki H. Dimitriou E. Kondili C. Choulaki E. Meleti D. Kafetzopoulos D. Georgopoulos G. Briassoulis A. García-de la Torre M. V. de la Torre-Prados T. Tsvetanova-Spasova P. Nuevo-Ortega C. Rueda-Molina A. Fernández-Porcel E. Camara-Sola L. Salido-Díaz A. García-Alcántara D. E. Meleti B. Suberviola J. Riera L. Rellan M. sanchez J. C. Robles E. Lopez R. Vicente E. Miñambres M. santibañez M. Le Guen J. Moore N. Mason M. Windpassinger O. Plattner E. Mascha D. I. Sessler Outcomes Research U. Melia J. Fontanet J. P. van den Berg M. Baylor College of Medicine Neurology/Neurocritical Care Houston USA Erasmus Hospital Intensive Care Medicine Brussels Belgium Centre Hospitalier Régional Orléans Réaimation Médicale Orléans France University of British Columbia Vancouver Canada University of Adelaide Discipline of Acute Care Medicine Adelaide Australia Royal Adelaide Hospital Intensive Care Adelaide Australia Griffith University Menzies Health Institute of Queensland Gold Coast Australia University of Adelaide Discipline of Medicine Adelaide Australia Kingston General Hospital Clinical Evaluation Research Unit Kingston Canada University of Oxford Nuffield Department of Clinical Neurosciences Oxford UK Oxford University Hospitals NHS Foundation Trust Neurosciences Intensive Care Unit Oxford UK King’s College Hospital Department of Neurosurgery London UK King’ College London Institute of Psychiatry Psychology and Neuroscience Department of Clinical Neuroscience London UK Rice University Computer Science Houston USA Baylor College of Medicine Neurosurgery Houston USA Baylor College of Medicine Pediatric Cardiology Houston USA University of Twente Clinical Neurophysiology Enschede Netherlands Rijnstate Hospital Neurology Arnhem Netherlands Medical Spectrum Twente Clinical Neurophysiology Enschede Netherlands Medical Spectrum Twente Intensive Care Enschede Netherlands Rijnstate Hospital Intensive Care Arnhem Netherlands CHUV Department of Intensive Care Medicine Neuroscience Critical Care Research Group Lausanne Switzerland Aga Khan University Hospital Anaesthesiology Karachi Pakistan Centro Hospitalar São João Intensive Care Porto Portugal Faculty of Medicine University of Porto Medicine Porto Portugal Faculdade de Ciências Universidade do Porto Departamento de Matemática Porto Portugal Centro de Matemática Universidade do Porto Porto Portugal The Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine Zaragoza Spain Centro Hospitalar

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Ophthalmologist-on-a-chip: Fully integrated microfluidic tear osmolarity and protein biomarker quantification for dry eye stratification

Ophthalmologist-on-a-chip: Fully integrated microfluidic tea...

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15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

作者： Karns, Kelly Herr, Amy E. University of California Berkeley University of California San Francisco Graduate Program in Bioengineering United States

ISBN: (纸本)9781618395955

Human tear film fluid offers tremendous potential as a non-invasive diagnostic fluid. However, the use of tear fluid in diagnostic medicine is limited owing to non-standardized collection methodologies and low volume availability. We present a first-reported microfluidic tear fluid biomarker assay which will serve as a foundation for both rapid biomarker validation and point-of-care ocular diagnostics. Our microfluidic approach demonstrates multiplexed quantitation of both tear fluid osmolarity and lactoferrin protein concentration in microliter quantities of human fluid from healthy and Sjögren's syndrome (SS) patients. Copyright © (2011) by the Chemical and Biological Microsystems Society.

关键词： Electrophoresis

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脂肪肝:MR成像及MR光谱数据与组织学分级的一致性

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国际医学放射学杂志 2012年第5期 473-473页

作者： S.M.Noworolski M.M.Lam R.B.Merriman L.Ferrell A.Qayyum 张薇 Departments of Radiology and Biomedical Imaging Berkeley-UCSF Graduate Program in BioengineeringUniversity of CaliforniaSan Francisco

摘要目的确定脂肪肝的MR成像及MR光谱数据与组织学分级的一致性是否受组织放大倍数、组织的异质性,或含脂质的组织与肝细胞之比的影响。方法本研究经伦理委员会批准,且符合HIPAA法案。已签署了知情同意书。对33例非酒精性脂肪肝病人和1... 详细信息

摘要目的确定脂肪肝的MR成像及MR光谱数据与组织学分级的一致性是否受组织放大倍数、组织的异质性,或含脂质的组织与肝细胞之比的影响。方法本研究经伦理委员会批准,且符合HIPAA法案。已签署了知情同意书。对33例非酒精性脂肪肝病人和15例健康志愿者进行了同-反相位MR成像和脂肪MR光谱测量的对比。

关键词：脂肪肝肝疾病 MR 组织学分级光谱数据

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Towards Next-Generation Proteomic Assays: Functional Materials as Sieving Matrices and Binding Scaffolds

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MRS Online Proceedings Library 2011年第1期1415卷 7-15页

作者： Samuel Q. Tia Alex J. Hughes Kelly Karns M. Kursad Araz Mei He Dohyun Kim Amy E. Herr University of California Berkeley Bioengineering Berkeley U.S.A. Graduate Program in Bioengineering University of California Berkeley/University of California San Francisco Berkeley U.S.A.

Next-generation bioanalytical approaches for protein-level measurements are advanced by the integration capacity of microfluidic design strategies, as well as the fine fluid and material control possible. Photopatterning of polymers within fluidic volumes is a key tool in the suite of technologies available for seamless integration of assay measurement modalities, as well as rapid target detection. Here, we overview recent advances in heterogeneous and homogeneous immunoassays using functional polymers, electrophoretic transport, and microdevices.

关键词： polymer devices fluidics

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Focus on discovering mechanisms: A relativistic, agent-directed, perfused liver

Focus on discovering mechanisms: A relativistic, agent-direc...

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2009 Spring Simulation Multiconference, SpringSim 2009

作者： Lam, Tai Ning Ropella, Glen E. P. Hunt, C. Anthony Graduate Program in Pharmaceutical Sciences and Pharmacogenomics University of California San Francisco United States Department of Bioengineering and Therapeutic Sciences BioSystems Group University of California 513 Parnassus Ave. San FranciscoCA United States Tempus Dictum Inc. United States

To facilitate integration and reconciliation between similar experiments, we need relativistic analogues that can be independent of experimental protocols;yet reasonably represent biological components and interactions among them, along with hypothesized mechanistic details. We designed, constructed and validated an analogue of a recirculating, isolated perfused liver used in a study of drug interactions between digoxin, rifampicin and quinidine. We believe these analogues can evolve into executable biological knowledge embodiments that provide concrete instances of knowledge and means to falsify mechanistic hypotheses.

关键词： Drug interactions

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Perception of 3-D layout in stereo displays

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Information Display 2009年第1期25卷 12-16页

作者： Banks, Martin S. Held, Robert T. Girshick, Ahna R. Science Program School of Optometry University of California at Berkeley Berkeley CA United States Joint Graduate Group in Bioengineering University of California San Francisco CA United States University of California at Berkeley Berkeley CA United States Department of Psychology Center for Neural Science New York University New York NY United States

As stereoscopic displays become more commonplace, it is more important than ever for those displays to create a faithful impression of the 3-D structure of the object or scene being portrayed. This article reviews cur... 详细信息

关键词： Chemicals

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Abstracts for the 6th Congress of Asian Sleep Research Society

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Sleep and Biological Rhythms 2009年第4期7卷 A1-A49页

作者： Seog Ju Kim In Kyoon Lyoo Yu-Jin Lee Do-Un Jeong Hirohiko Kanai Masanori Ookubo Atsushi Yoshimura Masako Okawa Noto Yamada Takeshi Munezawa Yoshitaka Kaneita Yoneatsu Osaki Hideyuki Kanda Tadahiro Ohtsu Masumi Minowa Kenji Suzuki Susumu Hijuchi Hiroyuki Suzuki Takashi Ohida Takashi Abe Yoko Komada Shoichi Asaoka Yuichi Inoue Jin-Seong Lee sang-Yong Cho Deependra Kumar Hruda N. Mallick Velayudhan M. Kumar Mahesh K. Kaushik Akihiro Karashima Noiihiro Katayama Mitsuyuki Nakao Ravindra P. Nagendra Sathiamma Sulekha Sathyaprabha T. Narasappa Pradhan Nityanadan Bindu M. Kutty M. Nirmala P. N. Ravindra Basavaraj Ramappa Tubaki T. N. Sathyaprabha D. Sudhakar G. S. Lavekar C. R. Chandrashekar Kazuyoshi Kitaoka Mika Shimizu Sachiko Chikahisa Kazuo Yoshizaki Hiroyoshi Sei Jong-Won Kim Misa Takegami Shin Yamazaki Yasuaki Hayashino Rei Ono Koji Otani Miho Sekiguchi Shinichi Konno Shunichi Fukuhara Antonia J. Jakobson Paul Fitzgerald Russell Conduit Xin Shirley Li Siu Ping Joyce Lam Wai Man Mandy Yu Yun Kwok Wing Kazue Okamoto-Mizuno Koh Mizuno Mituaki Yamamoto Shuichiro Shirakawa Hirokazu Doi Mikako Kato Kazuyuki Shinohara Masako Tamaki Shiori Matsuda Katsuo Yamazaki Tadao Hori Keiko Ogawa Kazumi Takahashi Kunio Kitahama Katuo Yamazaki Yoshimasa Koyama Kohei Shioda Yugo Ueda Yukiko Nakamura Clara Inoue Kazushige Goto Sunao Uchida Yuko Morita Yoshiko Honda Tohru Kodama Mari Hagihara Toru Nakajima Masato Saito Yoshihiko Koga Shinichiro Tanaka Hiroshi Yamadera Madoka Takahara Sachiko Suwa Minoru Onozuka Sadao Sato Fumiharu Togo Taiki Komatsu Takeshi Mitani Jongbae Choi Bin Zhang Taeko Sasai Hiromi Mitsubayashi Mitsuhiro Ohtsu Isao Hasegawa Tatsuya Ishii Akira Komori Asami Suzuki Yue Nakahara Mitsuyasu Hiroki Mariko Nakauma Nobuo Someya Tomomasa Ochiai Shouhei Komori Rayleigh Ping-Ying Chiang Zai-Ting Yeh Seong T. Kim Seung H. Yoon Jeong S. Kwon Jong H. Choi Hyung J. Ahn Youngsoo Kim Bolortuya Yunren Lichao Chen Radhika Basheer Robert W. Mccarley Robert E. Strecker Makoto Honda Tetsuaki Arai Miyuki Fukazawa Yutaka Honda Kuniaki T Department of Psychiatry Gachon University of Medicine and Science Incheon Republic of Korea Department of Psychiatry Seoul National University Seoul Republic of Korea Department of Neuropsychiatry and Center for Sleep and Chronobiology Seoul National University Hospital Seoul Republic of Korea Department of Neuropsychiatry Seoul National University Hospital Seoul Republic of Korea Seoul National University Hospital Seoul Republic of Korea Department of Psychiatry Shiga University of Medical Science Otsu Japan Division of Public Health Department of Social Medicine Nihon University School of Medicine Tokyo Japan Department of Public Health Nihon University School of Medicine Tokyo Japan Division of Environmental and Preventive Medicine Department of Social Medicine Faculty of Medicine Tottori University Yonago Japan Department of Hygiene and Preventive Medicine Fukushima Medical University Fukushima Japan Department of Public Health Showa University School of Medicine Tokyo Japan Faculty of Humanities Seitoku University Matsudo Japan Section on Behavioral Science Division of Clinical Research National Hospital Organization Kurihama Alcoholism Center Yokosuka Japan Department of Otolaryngology Second Hospital Fujita Health University Nagoya Japan National Hospital Organization Kurihama Alcoholism Center Kanagawa Japan Metropolitan Police Department Criminal Investigation Laboratory Tokyo Japan Japan Somnology Center Neuropsychiatrie Research Institute Tokyo Japan Department of Somnology Tokyo Medical University Tokyo Japan Japan Somnology Center Neuropsychiatric Research Institute Tokyo Japan Department of Somnology Tokyo Medical and Dental University Tokyo Japan Center for Sleep and Chronobiology Department of Psychiatry and Behavioral Science Seoul National University College of Medicine Seoul Republic of Korea Department of Psychiatry and Behavioral Science Center for Sleep and Chronobiology Seoul Republic of Korea Department of Physiology Al

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