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Discussion on renewal mode of historical residential area in modern cities

IOP Conference Series: Earth and Environmental Science 2018年第5期189卷

作者： Liu Qu Chuang Han College of Civil Engineering and Architecture Harbin University of Science and Technology Harbin Heilongjiang Province 150000 China College of Civil Engineering and Mechanics Yanshan University Qinhuangdao Hebei Province 066004 China School of Measurement and Communication Engineering Harbin University of Science and Technology Harbin Heilongjiang Province 150000 China

In the context of the continuous renewal of the urban environment, it is an important problem that how to coordinate the spatial form of the decline of the area and the demand for the high quality environment in the continuation of the cultural resources in the historical residential area. Through the analysis of several practical cases, this paper compares the updating background, the renewal target and the renewal mode of the different historical residential area, and probes into their renewal mode under the different urban development requirements.

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Room temperature continuous-wave excited biexciton emission in CsPbBr3 nanocrystals

arXiv

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arXiv 2018年

作者： Chen, Jie Zhang, Qing Du, Wenna Mi, Yang Shang, Qiuyu Shi, Jia Liu, Pengchong Sui, Xinyu Wu, Xianxin Wang, Rui Peng, Bo Zhong, Haizheng Xing, Guichuan Qiu, Xiaohui Sum, Tze Chien Liu, Xinfeng Division of Nanophotonics CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing100190 China University of Chinese Academy of Sciences 19 A Yuquan Rd Shijingshan District Beijing100049 China Department of Materials Science and Engineering College of Engineering Peking University Beijing100871 China Research Center for Wide Band Semiconductor Peking University China National Engineering Research Center of Electromagnetic Radiation Control Materials State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China Beijing Key Laboratory of Nanophotonics and Ultrafine Optoelectronic Systems School of Materials Science & Engineering Beijing Institute of Technology China Institute of Applied Physics and Materials Engineering University of Macau China School of Physical & Mathematical Sciences Nanyang Technological University 21 Nanyang Link Singapore

Biexcitons are a manifestation of many-body excitonic interactions crucial for quantum information and quantum computation in the construction of coherent combinations of quantum states. However, due to their small binding energy and low transition efficiency, most biexcitons in conventional semiconductors exist either at cryogenic temperature or under femtosecond pulse laser excitation. Here we demonstrate room temperature, continuous wave driven biexciton states in CsPbBr3 perovskite nanocrystals through coupling with a plasmonic nanogap. The room temperature CsPbBr3 biexciton excitation fluence (~100 mW/cm2) is reduced by ~1013 times in the Ag nanowire-film nanogaps. The giant enhancement of biexciton emission is driven by coherent biexciton-plasmon Fano interference. These results provide new pathways to develop high efficiency non-blinking single photon sources, entangled light sources and lasers based on biexciton states. Copyright © 2018, The Authors. All rights reserved.

关键词： Cesium compounds

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A low-cost and highly integrated control system for lower limb rehabilitation robot

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International Journal of High Performance Computing and Networking 2017年第6期10卷 488-497页

作者： Cao, Fucheng Li, Yuanchun Wang, Lirong Liu, Zhen College of Communication Engineering Jilin University Changchun Jilin China College of Electronic Information and Engineering Changchun University Changchun Jilin China Department of Control Engineering Changchun University of Technology Changchun Jilin China School of Electronic and Information Engineering Soochow University Suzhou Jiangsu China Graduate School of Engineering Nagasaki Institute of Applied Science Aba-machi 536 Nagasaki Japan

This paper presents a lower limb rehabilitation control system designed to train stroke patients by providing variable damping on the knee joint. The hardware based on the controller TMS320F28335 digital signal processor (DSP) and the software based on the DSP/BIOS embedded operation system are designed. The effective control of brushless DC (BLDC) motor can be implemented by combining with the upper impedance control algorithms and the underlying field-oriented control (FOC) control algorithm, which improves the performance of rehabilitation robot control system. The proposed integrated control system has robustness, dependability and works in real-time, and is easy to be upgraded and expanded. © 2017 Inderscience Enterprises Ltd.

关键词： Digital signal processors

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Author Correction: Enhancing untargeted metabolomics using metadata-based source annotation

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Nature biotechnology 2023年第11期41卷 1656页

作者： Julia M Gauglitz Kiana A West Wout Bittremieux Candace L Williams Kelly C Weldon Morgan Panitchpakdi Francesca Di Ottavio Christine M Aceves Elizabeth Brown Nicole C Sikora Alan K Jarmusch Cameron Martino Anupriya Tripathi Michael J Meehan Kathleen Dorrestein Justin P Shaffer Roxana Coras Fernando Vargas Lindsay DeRight Goldasich Tara Schwartz MacKenzie Bryant Gregory Humphrey Abigail J Johnson Katharina Spengler Pedro Belda-Ferre Edgar Diaz Daniel McDonald Qiyun Zhu Emmanuel O Elijah Mingxun Wang Clarisse Marotz Kate E Sprecher Daniela Vargas-Robles Dana Withrow Gail Ackermann Lourdes Herrera Barry J Bradford Lucas Maciel Mauriz Marques Juliano Geraldo Amaral Rodrigo Moreira Silva Flavio Protasio Veras Thiago Mattar Cunha Rene Donizeti Ribeiro Oliveira Paulo Louzada-Junior Robert H Mills Paulina K Piotrowski Stephanie L Servetas Sandra M Da Silva Christina M Jones Nancy J Lin Katrice A Lippa Scott A Jackson Rima Kaddurah Daouk Douglas Galasko Parambir S Dulai Tatyana I Kalashnikova Curt Wittenberg Robert Terkeltaub Megan M Doty Jae H Kim Kyung E Rhee Julia Beauchamp-Walters Kenneth P Wright Maria Gloria Dominguez-Bello Mark Manary Michelli F Oliveira Brigid S Boland Norberto Peporine Lopes Monica Guma Austin D Swafford Rachel J Dutton Rob Knight Pieter C Dorrestein Collaborative Mass Spectrometry Innovation Center University of California San Diego La Jolla CA USA. Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San Diego La Jolla CA USA. Beckman Center for Conservation Research San Diego Zoo Wildlife Alliance Escondido CA USA. Center for Microbiome Innovation Joan and Irwin Jacobs School of Engineering University of California San Diego La Jolla CA USA. Division of Biological Sciences University of California San Diego La Jolla CA USA. Department of Pediatrics School of Medicine University of California San Diego La Jolla CA USA. Bioinformatics and Systems Biology Program University of California San Diego La Jolla CA USA. Division of Rheumatology Allergy & Immunology Department of Medicine University of California San Diego La Jolla CA USA. Division of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN USA. Department of Integrative Physiology University of Colorado Boulder Boulder CO USA. Department of Population Health Sciences University of Wisconsin-Madison Madison WI USA. Servicio Autónomo Centro Amazónico de Investigación y Control de Enfermedades Tropicales Simón Bolívar Puerto Ayacucho Amazonas Venezuela. Department of Pediatrics Billings Clinic Billings MT USA. Department of Animal Science Michigan State University East Lansing MI USA. Department of Pharmacology Ribeirão Preto Medicinal School Center of Research in Inflammatory Diseases University of São Paulo Ribeirão Preto Sao Paolo Brazil. Multidisciplinary Health Institute Federal University of Bahia Vitória da Conquista Bahia Brazil. NPPNS Department of Biomolecular Sciences School of Pharmaceutical Sciences of Ribeirão Preto University of São Paulo Ribeirão Preto Sao Paolo Brazil. Department of Internal Medicine Ribeirão Preto Medical School Center of Research in Inflammatory Diseases University of São Paulo Ribeirão Preto Sao Paolo Brazil. Department

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Recent patents on electrospinning machine

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Recent Patents on Mechanical engineering 2016年第3期9卷 206-214页

作者： Jiang, Jingang Han, Yingshuai Yu, Xiaoyang Guo, Xiaowei Wang, Xin Robotics & ITS Engineering Research Center Harbin University of Science and Technology Harbin150080 China School of Measurement-Control Tech and Communications Engineering Harbin University of Science and Technology Harbin150080 China College of Mechanical and Electrical Engineering Northeast Forestry University Harbin100040 China

Background: Electrospinning technology is a simple and effective method for the production of polymer nanofibers. The electrospinning machine is the carrier of the spinning process, mainly includes high power voltage source, generating device and collecting device. Objective: To meet the increasing requirement of spinning parameters and efficiency, the mechanical structure of the machine is constantly being improved. Method: This paper reviews various representative patents related to electrospinning machine. Results: The differences of different types electrospinning machines are compared and analyzed and the characteristics are concluded. The main problems in its development are analyzed, the development trend is foreseen, and the current and future developments of the patents on electrospinning machine are discussed. Conclusion: The optimization of the electrospinning machine structure improves the efficiency of spinning and the electrospinning condition. For further enhancement, more patents on electrospinning machine should be invented. © 2016 Bentham Science Publishers.

关键词： Nanofibers

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Ductal carcinoma in situ detection in breast thermography by extreme learning machine and combination of statistical measure and fractal dimension

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Journal of Ambient Intelligence and Humanized Computing 2017年 1-11页

作者： Wang, Shui-Hua Muhammad, Khan Phillips, Preetha Dong, Zhengchao Zhang, Yu-Dong Jiangsu Key Laboratory of Advanced Manufacturing Technology HuaiyinJiangsu223003 China School of Computer Science and Technology Henan Polytechnic University JiaozuoHenan454000 China Ministry of Education Key Laboratory of Measurement and Control of Complex Systems of Engineering Southeast University Nanjing China College of Software Convergence Sejong University Seoul Korea Republic of Department of Informatics University of Leicester LeicesterLE1 7RH United Kingdom West Virginia School of Osteopathic Medicine 400 N Lee St LewisburgWV24901 United States Translational Imaging Division and MRI Unit Columbia University and New York State Psychiatric Institute New YorkNY10032 United States

Ductal carcinoma in situ (DCIS) is a severe breast disease. It generates little symptom and may be neglected in prodromal stage. In this study, we developed a novel DCIS detection method based on breast thermography, which can provide earlier alert than other exams. We created a 40 breast-thermogram dataset. We used six statistical measures, and we used fractal dimension to describe the texture measure. The extreme learning machine was used as the classifier. Our developed system yielded a sensitivity of 93.0 ± 2.6%, a specificity of 92.5 ± 2.6%, and an accuracy of 92.8 ± 1.8%. The extreme learning machine was better than support vector machine, artificial neural network, decision tree, and weighted k-nearest neighbors. Besides, our developed system was superior to six state-of-the-art approaches. © 2017 Springer-Verlag GmbH Germany, part of Springer Nature

关键词： Fractal dimension

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Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

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Nature human behaviour 2022年第9期6卷 1318-1319页

作者： Ke Wang Amit Goldenberg Charles A Dorison Jeremy K Miller Andero Uusberg Jennifer S Lerner James J Gross Bamikole Bamikole Agesin Márcia Bernardo Olatz Campos Luis Eudave Karolina Grzech Daphna Hausman Ozery Emily A Jackson Elkin Oswaldo Luis Garcia Shira Meir Drexler Anita Penić Jurković Kafeel Rana John Paul Wilson Maria Antoniadi Kermeka Desai Zoi Gialitaki Elizaveta Kushnir Khaoula Nadif Olalla Niño Bravo Rafia Nauman Marlies Oosterlinck Myrto Pantazi Natalia Pilecka Anna Szabelska I M M van Steenkiste Katarzyna Filip Andreea Ioana Bozdoc Gabriela Mariana Marcu Elena Agadullina Matúš Adamkovič Marta Roczniewska Cecilia Reyna Angelos P Kassianos Minja Westerlund Lina Ahlgren Sara Pöntinen Gabriel Agboola Adetula Pinar Dursun Azuka Ikechukwu Arinze Nwadiogo Chisom Arinze Chisom Esther Ogbonnaya Izuchukwu L G Ndukaihe Ilker Dalgar Handan Akkas Paulo Manuel Macapagal Savannah Lewis Irem Metin-Orta Francesco Foroni Megan Willis Anabela Caetano Santos Aviv Mokady Niv Reggev Merve A Kurfali Martin R Vasilev Nora L Nock Michal Parzuchowski Mauricio F Espinoza Barría Marek Vranka Markéta Braun Kohlová Ivan Ropovik Mikayel Harutyunyan Chunhui Wang Elvin Yao Maja Becker Efisio Manunta Gwenael Kaminski Jordane Boudesseul Dafne Marko Kortnee Evans David M G Lewis Andrej Findor Anais Thibault Landry John Jamir Benzon Aruta Manuel S Ortiz Zahir Vally Ekaterina Pronizius Martin Voracek Claus Lamm Maurice Grinberg Ranran Li Jaroslava Varella Valentova Giovanna Mioni Nicola Cellini Sau-Chin Chen Janis Zickfeld Karis Moon Habiba Azab Neil Levy Alper Karababa Jennifer L Beaudry Leanne Boucher W Matthew Collins Anna Louise Todsen Kevin van Schie Jáchym Vintr Jozef Bavolar Lada Kaliska Valerija Križanić Lara Samojlenko Razieh Pourafshari Sandra J Geiger Julia Beitner Lara Warmelink Robert M Ross Ian D Stephen Thomas J Hostler Soufian Azouaghe Randy McCarthy Anna Szala Caterina Grano Claudio Singh Solorzano Gulnaz Anjum William Jimenez-Leal Maria Bradford Laura Calderón Pérez Julio E Cruz Vásquez Oscar J Galindo-Caballero Juan Cami Harvard Kennedy School Harvard University Cambridge MA USA. Harvard Business School Harvard University Cambridge MA USA. Kellogg School of Management Northwestern University Evanston IL USA. Department of Psychology Willamette University Salem OR USA. millerj@willamette.edu. Institute of Psychology University of Tartu Tartu Estonia. Harvard Kennedy School and Department of Psychology Harvard University Cambridge MA USA. Department of Psychology Stanford University Stanford CA USA. Adekunle Ajasin University Akungba Akoko Nigeria. Faculdade de Psicologia e Ciências da Educação Universidade do Porto Porto Portugal. University of Deusto Barakaldo Spain. University of Navarra Pamplona Spain. University of Valencia Valencia Spain. Stockholm University Stockholm Sweden. California State University Northridge Los Angeles CA USA. Indiana University of Pennsylvania Indiana PA USA. Universidad de Navarra Pamplona Spain. Department of Cognitive Psychology Institute of Cognitive Neuroscience Ruhr University Bochum Bochum Germany. Kindergarten Kustošija Zagreb Croatia. GC University Lahore Lahore Pakistan. Montclair State University Jersey City NJ USA. European University of Cyprus Nicosia Cyprus. Indiana University of Pennsylvania Akron PA USA. Leiden University Culemborg The Netherlands. Stockholm Sweden. Poggio Imperiale Italy. Barakaldo Spain. Islamabad Pakistan. Gent Belgium. Oxford Internet Institute University of Oxford Oxford UK. Warsaw Poland. Queen's University Belfast Belfast Ireland. Universiteit Leiden Leiden The Netherlands. Institute of Psychology Jagiellonian University Krakow Poland. Department of Psychology Lucian Blaga University of Sibiu Sibiu Romania. Carol Davila University of Medicine and Pharmacy Bucharest Romania. National Research University Higher School of Economics Moscow Russia. Institute of Psychology Faculty of Arts University of Presov Presov Slovakia. Institute of Social Sciences CSPS Sl

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Search for continuous gravitational waves from 20 accreting millisecond x-ray pulsars in O3 LIGO data

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Physical Review D 2022年第2期105卷 022002-022002页

作者： R. Abbott T. D. Abbott F. Acernese K. Ackley C. Adams N. Adhikari R. X. Adhikari V. B. Adya C. Affeldt D. Agarwal M. Agathos K. Agatsuma N. Aggarwal O. D. Aguiar L. Aiello A. Ain T. Akutsu S. Albanesi A. Allocca P. A. Altin A. Amato C. Anand S. Anand A. Ananyeva S. B. Anderson W. G. Anderson M. Ando T. Andrade N. Andres T. Andrić S. V. Angelova S. Ansoldi J. M. Antelis S. Antier S. Appert Koji Arai Koya Arai Y. Arai S. Araki A. Araya M. C. Araya J. S. Areeda M. Arène N. Aritomi N. Arnaud S. M. Aronson K. G. Arun H. Asada Y. Asali G. Ashton Y. Aso M. Assiduo S. M. Aston P. Astone F. Aubin C. Austin S. Babak F. Badaracco M. K. M. Bader C. Badger S. Bae Y. Bae A. M. Baer S. Bagnasco Y. Bai L. Baiotti J. Baird R. Bajpai M. Ball G. Ballardin S. W. Ballmer A. Balsamo G. Baltus S. Banagiri D. Bankar J. C. Barayoga C. Barbieri B. C. Barish D. Barker P. Barneo F. Barone B. Barr L. Barsotti M. Barsuglia D. Barta J. Bartlett M. A. Barton I. Bartos R. Bassiri A. Basti M. Bawaj J. C. Bayley A. C. Baylor M. Bazzan B. Bécsy V. M. Bedakihale M. Bejger I. Belahcene V. Benedetto D. Beniwal T. F. Bennett J. D. Bentley M. BenYaala F. Bergamin B. K. Berger S. Bernuzzi D. Bersanetti A. Bertolini J. Betzwieser D. Beveridge R. Bhandare U. Bhardwaj D. Bhattacharjee S. Bhaumik I. A. Bilenko G. Billingsley S. Bini R. Birney O. Birnholtz S. Biscans M. Bischi S. Biscoveanu A. Bisht B. Biswas M. Bitossi M.-A. Bizouard J. K. Blackburn C. D. Blair D. G. Blair R. M. Blair F. Bobba N. Bode M. Boer G. Bogaert M. Boldrini L. D. Bonavena F. Bondu E. Bonilla R. Bonnand P. Booker B. A. Boom R. Bork V. Boschi N. Bose S. Bose V. Bossilkov V. Boudart Y. Bouffanais A. Bozzi C. Bradaschia P. R. Brady A. Bramley A. Branch M. Branchesi J. E. Brau M. Breschi T. Briant J. H. Briggs A. Brillet M. Brinkmann P. Brockill A. F. Brooks J. Brooks D. D. Brown S. Brunett G. Bruno R. Bruntz J. Bryant T. Bulik H. J. Bulten A. Buonanno R. Buscicchio D. Buskulic C. Buy R. L. Byer L. Cadonati G. Cagnoli C. Cahillane J. Calderón Bustillo J. D. Callaghan T. A. Callister E. Ca LIGO Laboratory California Institute of Technology Pasadena California 91125 USA Louisiana State University Baton Rouge Louisiana 70803 USA Dipartimento di Farmacia Università di Salerno I-84084 Fisciano Salerno Italy INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo I-80126 Napoli Italy OzGrav School of Physics & Astronomy Monash University Clayton 3800 Victoria Australia LIGO Livingston Observatory Livingston Louisiana 70754 USA University of Wisconsin-Milwaukee Milwaukee Wisconsin 53201 USA OzGrav Australian National University Canberra Australian Capital Territory 0200 Australia Max Planck Institute for Gravitational Physics (Albert Einstein Institute) D-30167 Hannover Germany Leibniz Universität Hannover D-30167 Hannover Germany Inter-University Centre for Astronomy and Astrophysics Pune 411007 India University of Cambridge Cambridge CB2 1TN United Kingdom Theoretisch-Physikalisches Institut Friedrich-Schiller-Universität Jena D-07743 Jena Germany University of Birmingham Birmingham B15 2TT United Kingdom Center for Interdisciplinary Exploration & Research in Astrophysics (CIERA) Northwestern University Evanston Illinois 60208 USA Instituto Nacional de Pesquisas Espaciais 12227-010 São José dos Campos São Paulo Brazil Gravity Exploration Institute Cardiff University Cardiff CF24 3AA United Kingdom INFN Sezione di Pisa I-56127 Pisa Italy Gravitational Wave Science Project National Astronomical Observatory of Japan (NAOJ) Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan (NAOJ) Mitaka City Tokyo 181-8588 Japan INFN Sezione di Torino I-10125 Torino Italy Università di Napoli “Federico II” Complesso Universitario di Monte S. Angelo I-80126 Napoli Italy Université de Lyon Université Claude Bernard Lyon 1 CNRS Institut Lumière Matière F-69622 Villeurbanne France Department of Physics The University of Tokyo Bunkyo-ku Tokyo 113-0033 Japan Research Center for the Early Un

Results are presented of searches for continuous gravitational waves from 20 accreting millisecond x-ray pulsars with accurately measured spin frequencies and orbital parameters, using data from the third observing run of the Advanced LIGO and Advanced Virgo detectors. The search algorithm uses a hidden Markov model, where the transition probabilities allow the frequency to wander according to an unbiased random walk, while the J-statistic maximum-likelihood matched filter tracks the binary orbital phase. Three narrow subbands are searched for each target, centered on harmonics of the measured spin frequency. The search yields 16 candidates, consistent with a false alarm probability of 30% per subband and target searched. These candidates, along with one candidate from an additional target-of-opportunity search done for SAX J1808.4−3658, which was in outburst during one month of the observing run, cannot be confidently associated with a known noise source. Additional follow-up does not provide convincing evidence that any are a true astrophysical signal. When all candidates are assumed nonastrophysical, upper limits are set on the maximum wave strain detectable at 95% confidence, h095%. The strictest constraint is h095%=4.7×10−26 from IGR J17062−6143. Constraints on the detectable wave strain from each target lead to constraints on neutron star ellipticity and r-mode amplitude, the strictest of which are ε95%=3.1×10−7 and α95%=1.8×10−5 respectively. This analysis is the most comprehensive and sensitive search of continuous gravitational waves from accreting millisecond x-ray pulsars to date.

关键词： Gravitational waves Binary stars Neutron stars & pulsars

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Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: the Global Burden of Diseases Study 2019

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The Lancet HIV 2021年第10期8卷 e633-e651页

作者： Jahagirdar, Deepa Walters, Magdalene K. Novotney, Amanda Brewer, Edmond D. Frank, Tahvi D. Carter, Austin Biehl, Molly H. Abbastabar, Hedayat Abhilash, E.S. Abu-Gharbieh, Eman Abu-Raddad, Laith Jamal Adekanmbi, Victor Adeyinka, Daniel Adedayo Adnani, Qorinah Estiningtyas Sakilah Afzal, Saira Aghababaei, Soodabeh Ahinkorah, Bright Opoku Ahmad, Sajjad Ahmadi, Keivan Ahmadi, Sepideh Ahmadpour, Ehsan Ahmed, Muktar Beshir Rashid, Tarik Ahmed Salih, Yusra Ahmed Aklilu, Addis Akram, Tayyaba Akunna, Chisom Joyqueenet Al Hamad, Hanadi Alahdab, Fares Alanezi, Fahad Mashhour Aleksandrova, Ekaterina A. Alene, Kefyalew Addis Ali, Liaqat Alipour, Vahid Almustanyir, Sami Alvis-Guzman, Nelson Ameyaw, Edward Kwabena Amu, Hubert Andrei, Catalina Liliana Andrei, Tudorel Anvari, Davood Arabloo, Jalal Aremu, Olatunde Arulappan, Judie Atnafu, Desta Debalkie Quintanilla, Beatriz Paulina Ayala Ayza, Muluken Altaye Azari, Samad Darshan, B.B. Banach, Maciej Bärnighausen, Till Winfried Barra, Fabio Barrow, Amadou Basu, Sanjay Bazargan-Hejazi, Shahrzad Belay, Habtamu Gebrehana Berheto, Tezera Moshago Bezabhe, Woldesellassie Mequanint Bezabih, Yihienew Mequanint Bhagavathula, Akshaya Srikanth Bhardwaj, Nikha Bhardwaj, Pankaj Bhattacharyya, Krittika Bibi, Sadia Bijani, Ali Bisignano, Catherine Bolarinwa, Obasanjo Afolabi Boloor, Archith Boltaev, Azizbek A. Briko, Nikolay Ivanovich Buonsenso, Danilo Burkart, Katrin Butt, Zahid A. Cao, Chao Charan, Jaykaran Chatterjee, Souranshu Chattu, Soosanna Kumary Chattu, Vijay Kumar Choudhari, Sonali Gajanan Chu, Dinh-Toi Couto, Rosa A.S. Cowden, Richard G. Dachew, Berihun Assefa Dadras, Omid Dagnew, Amare Belachew Dahlawi, Saad M.A. Dai, Xiaochen Dandona, Lalit Dandona, Rakhi das Neves, José Degenhardt, Louisa Demeke, Feleke Mekonnen Desta, Abebaw Alemayehu Deuba, Keshab Dhamnetiya, Deepak Dhungana, Govinda Prasad Dianatinasab, Mostafa Diaz, Daniel Djalalinia, Shirin Doan, Linh Phuong Dorostkar, Fariba Edinur, Hisham Atan Effiong, Andem Eftekharzadeh, Sahar El Sayed Zaki, Maysaa Elayedath, Rajesh Elhadi, Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Division of Allergy and Infectious Diseases University of Washington Seattle WA United States Department of Global Health University of Washington Seattle WA United States School of Social Work University of Washington Seattle WA United States Department of Medicine University of Washington Seattle WA United States Vagelos College of Physicians and Surgeones Columbia University Medical Center New York NY United States Division of Data Analytics and Delivery for Impact WHO Geneva Switzerland Advanced Diagnostic and Interventional Radiology Research Centre Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Centre Tehran University of Medical Sciences Tehran Iran School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Paediatric Chronic Kidney Disease Research Centre Tehran University of Medical Sciences Tehran Iran Department of Psychiatry Tehran University of Medical Sciences Tehran Iran Metabolomics and Genomics Research Centre Tehran University of Medical Sciences Tehran Iran Sina Trauma and Surgery Research Centre Tehran University of Medical Sciences Tehran Iran Research Centre for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Non-Communicable Diseases Research Centre Tehran University of Medical Sciences Tehran Iran Department of Botany Sree Narayana Guru College Chelannur Kozhikode India Clinical Sciences Department University of Sharjah Sharjah United Arab Emirates Mass Communication Department University of Sharjah Sharjah United Arab Emirates Department of Health-Care Policy and Research Weill Cornell Medical College in Qatar Doha Qatar Department of Population Medicine Ca

Background: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. Methods: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). Findings: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1–38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78–0·91) per female living with HIV in 2019, 0·99 male infections (0·91–1·10) for every female infection, and 1·02 male deaths (0·95–1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58–35·43, and a 39·66% decrease in deaths, 36·49–42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05–0·06) and the global incidence-to-mortality ratio was

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Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

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Nature communications 2025年第1期16卷 4235-4235页

作者： Cecilia Anza-Ramirez J. Jaime Miranda Benedetta Armocida Jorge César Correia Harriette Gillian Christine Van Spall David Beran Amirali Aali Kalkidan Hassen Abate Semagn Mekonnen Abate Cristiana Abbafati Mohsen Abbasi-Kangevari Zeinab Abbasi-Kangevari Zahra Aryan Sina Azadnajafabad Mohammadreza Azangou-Khyavy Seyyed-Hadi Ghamari Mohammad Keykhaei Javad Khanali Sara Momtazmanesh Fateme Montazeri Shayan Rahmani Mohammad-Mahdi Rashidi Nazila Rezaei Negar Rezaei Sahar Saeedi Moghaddam Hossein Hassanian-Moghaddam Ali-Asghar Kolahi Ali Nikoobar Hedayat Abbastabar Ahmed M. Abdel-Azeem Michael Abdelmasseh Juan Sanabria Sherief Abd-Elsalam Ahmed Abdelwahab Gholamreza Abdoli Mohammad Abdollahi Meriem Abdoun Deldar Morad Abdulah Abu Yousuf Md Abdullah Ame Mehadi Abdurehman Getachew Abebe Aidin Abedi Chirag P. Doshi Vida Abedi Hassan Abidi Richard Gyan Aboagye Hassan Abolhassani Nima Rezaei Lucas Guimarães Abreu Michael R. M. Abrigo Yonas Derso Abtew Hiwa Abubaker Ali Eman Abu-Gharbieh Hiba Jawdat Barqawi Rabih Halwani Maha Mohamed Saber-Ayad Iman M. Talaat Ahmed Abu-Zaid Manfred Mario Kokou Accrombessi Juan Manuel Acuna Denberu Eshetie Adane Tigist Demssew Adane Isaac Yeboah Addo Giovanni Addolorato Oluwafemi Atanda Adeagbo Victor Adekanmbi Miracle Ayomikun Adesina Isaac Iyinoluwa Olufadewa Olatunji O. Adetokunboh Daniel Adedayo Adeyinka Qorinah Estiningtyas Sakilah Adnani Aanuoluwapo Adeyimika Afolabi Olayinka Stephen Ilesanmi Muhammad Sohail Afzal Saira Afzal Gina Agarwal Prerna Agarwal Pradyumna Agasthi Anurag Agrawal Marcela Agudelo-Botero Adolfo Martinez-Valle Bright Opoku Ahinkorah Aqeel Ahmad Sajjad Ahmad Sohail Ahmad Tauseef Ahmad Ali Ahmadi Siamak Sabour Keivan Ahmadi Sanjay Basu Sepideh Ahmadi Ali Ahmed Shaun Wen Huey Lee Ayman Ahmed Haroon Ahmed Jivan Qasim Ahmed Gahin Abdulraheem Tayib Yahya Yahya Luai A. Ahmed Iffat Elbarazi Syed Mahboob Shah Janardhana P. Aithala Marjan Ajami Budi Aji Hossein Akbarialiabad Yibeltal Akelew Meisam Akhlaghdoust Elham Jamshidi Addis Aklilu Azene Tesfaye Melat Woldemariam Maxwell Ak CRONICAS Center of Excellence in Chronic Diseases Universidad Peruana Cayetano Heredia Lima Peru School of Medicine Universidad Peruana Cayetano Heredia Lima Peru Sydney School of Public Health Faculty of Medicine and Health University of Sydney Sydney NSW Australia Faculty of Epidemiology and Population Health London School of Hygiene & Tropical Medicine London UK Division of Tropical and Humanitarian Medicine University of Geneva Geneva Switzerland Department of Cardiovascular Endocrine-metabolic Diseases and Aging Istituto Superiore di Sanità Rome Italy Division of Endocrinology Diabetology Nutrition and Therapeutic Patient Education Department of Medicine Geneva University Hospitals Geneva Switzerland Department of Medicine and Department of Health Research Evidence and Impact McMaster University Hamilton ON Canada Research Institute of St. Joe’s Hamilton ON Canada Population Health Research Institute Hamilton Canada Geneva University Hospitals Geneva Switzerland Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran Department of Nutrition and Dietetics Jimma University Jimma Ethiopia Anesthesiology Department Dilla University Addis Ababa Ethiopia Department of Juridical and Economic Studies La Sapienza University Rome Italy Non-Communicable Diseases Research Center Tehran University of Medical Sciences Tehran Iran Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Brigham and Women’s Hospital Harvard University Boston MA USA Students’ Scientific Research Center (SSRC) Tehran University of Medical Sciences Tehran Iran School of Medicine Tehran University of Medical Sciences Tehran Iran School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran Endocrinology and Metabolism Research Institute Tehran University of Medical Sciences Tehran Iran Chapter of Addiction Medicine University of Sydney Sydney NSW Australia Advanced Diagnostic and Intervent

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index, presenting total numbers and contributions to burden metrics such as Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost (YLL). Approximately 68% of DALYs were attributed to chronic care, while 27% were due to acute care. Chronic care needs increased with age, representing 86% of YLDs and 71% of YLLs, and accounting for 93% of YLDs from sequelae. These findings highlight that chronic care needs far exceed acute care needs globally, necessitating health systems to adapt accordingly. © 2025. The Author(s).

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