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circ2CBA: prediction of circRNA-RBP binding sites combining deep learning and attention mechanism

Frontiers of computer science 2023年第5期17卷 217-225页

作者： Yajing GUO Xiujuan LEI Lian LIU Yi PAN School of Computer Science Shaanxi Normal UniversityXi’an 710119China Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Circular RNAs(circRNAs)are RNAs with closed circular structure involved in many biological processes by key interactions with RNA binding proteins(RBPs).Existing methods for predicting these interactions have limitations in feature *** view of this,we propose a method named circ2CBA,which uses only sequence information of circRNAs to predict circRNA-RBP binding *** have constructed a data set which includes eight ***,circ2CBA encodes circRNA sequences using the one-hot ***,a two-layer convolutional neural network(CNN)is used to initially extract the *** CNN,circ2CBA uses a layer of bidirectional long and short-term memory network(BiLSTM)and the self-attention mechanism to learn the *** AUC value of circ2CBA reaches *** of circ2CBA with other three methods on our data set and an ablation experiment confirm that circ2CBA is an effective method to predict the binding sites between circRNAs and RBPs.

关键词： circRNAs RBPs CNN BiLSTM self-attention mechanism

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Leveraging EfficientNetB3 in a Deep Learning Framework for High-Accuracy MRI Tumor Classification

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computers, Materials & Continua 2024年第10期81卷 867-883页

作者： Mahesh Thyluru Ramakrishna Kuppusamy Pothanaicker Padma Selvaraj Surbhi Bhatia Khan Vinoth Kumar Venkatesan Saeed Alzahrani Mohammad Alojail Department of Computer Science&Engineering Faculty of Engineering and TechnologyJAIN(Deemed-to-be University)Bengaluru562112India School of Computer Science and Engineering VIT-AP UniversityAmaravati522241India Department of Computer Science&Technology Madanapalle Institute of Technology&ScienceMadanapalle517325India School of Science Engineering and EnvironmentUniversity of SalfordManchesterM54WTUK School of Computer Science Engineering&Information Systems(SCORE) Vellore Institute of Technology(VIT)Vellore632014India Management Information System Department College of Business AdministrationKing Saud UniversityRiyadh11531Saudi Arabia Adjunct Research Faculty Centre for Research Impact&OutcomeChitkara UniversityRajpuraPunjab140401India

Brain tumor is a global issue due to which several people suffer,and its early diagnosis can help in the treatment in a more efficient *** different types of brain tumors,including gliomas,meningiomas,pituitary tumors,as well as confirming the absence of tumors,poses a significant challenge using MRI *** approaches predominantly rely on traditional machine learning and basic deep learning methods for image *** methods often rely on manual feature extraction and basic convolutional neural networks(CNNs).The limitations include inadequate accuracy,poor generalization of new data,and limited ability to manage the high variability in MRI *** the EfficientNetB3 architecture,this study presents a groundbreaking approach in the computational engineering domain,enhancing MRI-based brain tumor *** approach highlights a major advancement in employing sophisticated machine learning techniques within computer science and engineering,showcasing a highly accurate framework with significant potential for healthcare *** model achieves an outstanding 99%accuracy,exhibiting balanced precision,recall,and F1-scores across all tumor types,as detailed in the classification *** successful implementation demonstrates the model’s potential as an essential tool for diagnosing and classifying brain tumors,marking a notable improvement over current *** integration of such advanced computational techniques in medical diagnostics can significantly enhance accuracy and efficiency,paving the way for wider *** research highlights the revolutionary impact of deep learning technologies in improving diagnostic processes and patient outcomes in neuro-oncology.

关键词： Deep learning MRI brain tumor cassification EfficientNetB3 computational engineering healthcare technology artificial intelligence in medical imaging tumor segmentation neuro-oncology

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Design an optimization based ensemble machine learning framework for detecting rice leaf diseases

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Multimedia Tools and Applications 2024年第36期83卷 84401-84424页

作者： Rajasekhar, Veeramreddy Arulselvi, Gnanasekaran Babu, K. Suresh Department of Computer Science Engineering Annamalai University Tamilnadu Chidambaram India Department of Computer Science and Engineering Faculty of Engineering and Technology Annamalai University Tamil Nadu Chidambaram India International School of Technology and Sciences for Women East Gonagudem Rajanagaram A.P Rajamahendravaram India

The agriculture industry is currently dealing with serious issues with rice plants as a result of illnesses that decrease the quantity and output of the harvest. Numerous fungi and bacteria diseases harm plants that affect the growth of yield. So identification of the detection of crop diseases is essential for enhancing the productivity of crops. Many techniques have been developed to improve disease detection in crops but there are still some issues such as noise, time consumption, delay, poor segmentation, and less accuracy. To overcome these issues, this paper, designed a Spider Monkey-based Random Forest (SMbRF) model for accurate detection and classification of rice leaf diseases and the designed model was implemented in the Python system. The main aim is to develop an optimization-based random forest technique for accurate prediction of rice leaf disease by exact segmentation. Initially, preprocessing is performed to enhance the data quality and remove errors. Furthermore, separate the lesions using mean shift image segmentation and extract the shape and color features to improve the detection results of the developed model. As well, spider monkey fitness is updated in the RF classification layer for accurate classification of diseases and improves accuracy with less execution time. The experiment results show the reliability and efficiency of the designed model, it attains better performance in accuracy, sensitivity, specificity, and precision. The designed model attained 99.29% accuracy, 99.52% sensitivity, 98.76% precision, and 99% specificity proving the scalability of the designed model. © The Author(s), under exclusive licence to Springer science+Business Media, LLC, part of Springer Nature 2024.

关键词： Machine learning

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Hybrid Optimization Algorithm for Handwritten Document Enhancement

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computers, Materials & Continua 2024年第3期78卷 3763-3786页

作者： Shu-Chuan Chu Xiaomeng Yang Li Zhang Václav Snášel Jeng-Shyang Pan College of Computer Science and Engineering Shandong University of Science and TechnologyQingdao266590China School of Information and Control Engineering Qingdao University of TechnologyQingdao266520China Faculty of Electrical Engineering and Computer Science VŠB-TU OstravaOstrava70080Czech Republic Department of Information Management Chaoyang University of TechnologyTaichung41349Taiwan

The Gannet Optimization Algorithm (GOA) and the Whale Optimization Algorithm (WOA) demonstrate strong performance;however, there remains room for improvement in convergence and practical applications. This study introduces a hybrid optimization algorithm, named the adaptive inertia weight whale optimization algorithm and gannet optimization algorithm (AIWGOA), which addresses challenges in enhancing handwritten documents. The hybrid strategy integrates the strengths of both algorithms, significantly enhancing their capabilities, whereas the adaptive parameter strategy mitigates the need for manual parameter setting. By amalgamating the hybrid strategy and parameter-adaptive approach, the Gannet Optimization Algorithm was refined to yield the AIWGOA. Through a performance analysis of the CEC2013 benchmark, the AIWGOA demonstrates notable advantages across various metrics. Subsequently, an evaluation index was employed to assess the enhanced handwritten documents and images, affirming the superior practical application of the AIWGOA compared with other algorithms.

关键词： Metaheuristic algorithm gannet optimization algorithm hybrid algorithm handwritten document enhancement

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Tensor-Based Factorial Hidden Markov Model for Cyber-Physical-Social Services

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IEEE Transactions on Services Computing 2025年第3期18卷 1825-1837页

作者： Lu, Zhixing Yang, Laurence T. Azman, Azreen Zhang, Shunli Zhou, Fang Hainan University School of Computer Science and Technology Hainan China Universiti Putra Malaysia Faculty of Computer Science and Information Technology Serdang Malaysia Zhengzhou University School of Computer and Artificial Intelligence School of Software Engineering Zhengzhou China Huazhong University of Science and Technology School of Computer Science and Technology Huazhong China St. Francis Xavier University Department of Computer Science Canada

With the rapid development and widespread application of information, computer, and communication technologies, Cyber-Physical-Social Systems (CPSS) have gained increasing importance and attention. To enable intelligent applications and provide better services for CPSS users, efficient data analytical models are crucial. This paper presents a novel data analytic framework for CPSS services. First, a Tensor-Based Factorial Hidden Markov Model (T-FHMM) is introduced to comprehensively analyze multi-user activity features, enhancing CPSS activity analytics. A tensor-based Forward-Backward algorithm is then designed for T-FHMM to efficiently perform evaluation tasks using multiple probabilistic computing micro-services. Additionally, a tensor-based Baum-Welch algorithm is developed to accurately learn model parameters via parameter optimization micro-services. Furthermore, a tensor-based Viterbi algorithm is implemented with specific micro-services to improve prediction tasks. Finally, the comprehensive performance of the proposed model and algorithms is validated on three open datasets through self-comparison and other-comparison. Experimental results demonstrate that the proposed method outperforms compared methods in terms of accuracy, precision, recall, and F1-score. © 2008-2012 IEEE.

关键词： Viterbi algorithm

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GRIPPY: A VR Grip Controller for Combating Sarcopenia in Elderly

GRIPPY: A VR Grip Controller for Combating Sarcopenia in Eld...

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2025 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops, VRW 2025

作者： Leong, Hoilam Wu, Jiang Lai, Yoke Chin Faulon, Loïc Sun, Xu Lee, Boon Giin University of Nottingham Faculty of Science and Engineering Department of Mechanical Materials and Manufacturing Engineering Ningbo China School of Computer Science China

ISBN: (纸本)9798331514846

As the global population ages, sarcopenia - age-related muscle decline - demands innovative solutions. This paper introduces GRIPPY, a VR grip controller that transforms basic handgrip exercises into immersive, gamified tasks. By integrating sensor-based interaction and VR gameplay, older adults can strengthen grip while maintaining higher motivation. A preliminary test with three participants (ages 68-80) revealed key usability insights, underscoring GRIPPY's potential for enhanced rehabilitation. Future work will refine its design and validate long-term efficacy. © 2025 IEEE.

关键词： Elderly Rehabilitation Grip Strength Immersive Exercise Interactive Training Sarcopenia Virtual Reality

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Multi-Task Learning for Alzheimer's Disease Diagnosis and Mini-Mental State Examination Score Prediction

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Big Data Mining and Analytics 2024年第3期7卷 828-842页

作者： Jin Liu Xu Tian Hanhe Lin Hong-Dong Li Yi Pan Hunan Provincial Key Lab on Bioinformatics School of Computer Science and EngineeringCentral South UniversityChangsha 410083China Xinjiang Engineering Research Center of Big Data and Intelligent Software School of SoftwareXinjiang UniversityUrumqi 830091China School of Science and Engineering University of DundeeDundeeDD14HNUK Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Accurately diagnosing Alzheimer's disease is essential for improving elderly ***,accurate prediction of the mini-mental state examination score also can measure cognition impairment and track the progression of Alzheimer's ***,most of the existing methods perform Alzheimer's disease diagnosis and mini-mental state examination score prediction separately and ignore the relation between these two *** address this challenging problem,we propose a novel multi-task learning method,which uses feature interaction to explore the relationship between Alzheimer's disease diagnosis and minimental state examination score *** our proposed method,features from each task branch are firstly decoupled into candidate and non-candidate parts for ***,we propose feature sharing module to obtain shared features from candidate features and return shared features to task branches,which can promote the learning of each *** validate the effectiveness of our proposed method on multiple *** Alzheimer's disease neuroimaging initiative 1 dataset,the accuracy in diagnosis task and the root mean squared error in prediction task of our proposed method is 87.86%and 2.5,*** results show that our proposed method outperforms most state-of-the-art *** proposed method enables accurate Alzheimer's disease diagnosis and mini-mental state examination score ***,it can be used as a reference for the clinical diagnosis of Alzheimer's disease,and can also help doctors and patients track disease progression in a timely manner.

关键词： multi-task learning Alzheimer's disease diagnosis mini-mental state examination score prediction

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A Novel Deep Neural Network Architecture based GAN-DRANet for DOA Sensing With an Enhanced Performance in Low SNR

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IEEE Internet of Things Journal 2025年第13期12卷 22610-22622页

作者： Bai, Jiatong Shu, Feng Gao, Wei Wu, Guilu Yang, Weiwei Chen, Riqing Zhuang, Zhihong Hainan University School of Information and Communication Engineering Haikou570228 China Hainan University School of Information and Communication Engineering Collaborative Innovation Center of Information Technology Haikou570228 China Tibet University China School of Information Science and Technology Lhasa850000 China Nanjing University of Science and Technology School of Electronic and Optical Engineering Nanjing210094 China College of Communications Engineering Army Engineering University of PLA Nanjing China Fujian Agriculture and Forestry University School of Computer Science and Information Engineering Fuzhou350002 China

In extremely low signal-to-noise ratio (SNR) region, the useful features of the signal are weakened by higher-power noise, making it difficult for conventional direction-of-arrival (DOA) estimation methods to adequately exploit and extract the low-SNR signal features. Thus, a generative adversarial network (GAN) is presented to learn the underlying features and complex distributions of high-SNR covariance matrices. The introduced GAN establishes a mapping between low-SNR and high-SNR covariance matrices, thereby generating first-rate high-SNR covariance matrices that closely resemble real high-SNR matrices. Also, it effectively captures signal features that are overwhelmed by excessive noise power. Additionally, to improve the performance of convolutional neural network (CNN)-based DOA estimation models in medium-to-high SNR ranges, a deep residual attention network (DRANet) is designed to significantly enhance DOA estimation accuracy in such SNR region. By integrating residual and attention modules, the network effectively filters key features. This enhances feature learning and adaptability, allowing it to capture DOA-related features more proficiently. The experimental results indicate that the developed GAN-DRANet approach can approach the CRLB in the extremely-low SNR range and improves the estimation resolution limits of the other two DL-based methods, DNN and CNN, in medium to high SNR conditions. © 2014 IEEE.

关键词： Generative adversarial networks

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A hybrid CNN-SVM model optimized with PSO for accurate and non-invasive brain tumor classification

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Neural Computing and Applications 2025年 1-30页

作者： Semwal, Tanay Jain, Sania Mohanta, Agradeep Jain, Ankur School of Computer Science and Engineering VIT Bhopal University Madhya Pradesh Kothri Kalan India Faculty of Science The Maharaja Sayajirao University of Baroda Gujarat Vadodara India

Brain and central nervous system (CNS) cancers are the leading cause of cancer-related mortality, presenting significant diagnostic challenges due to their aggressive nature and diverse manifestations. While biopsies are the gold standard for diagnosis, their invasiveness and associated risks necessitate the development of noninvasive, automated tools for accurate and rapid tumor classification. This research presents a hybrid approach that combines a convolutional neural network (CNN) for feature extraction with a support vector machine (SVM) classifier, optimized by particle swarm optimization (PSO). The proposed model achieves multiclass classification across four tumor categories: glioma, meningioma, pituitary, and no tumor. The model incorporates data augmentation, dropout layers, pooling, batch-normalization, and hyperparameter tuning via PSO, to enhance generalization and minimize overfitting. The experimental analysis on the brain tumor MRI dataset highlights the model's strong performance, with an overall accuracy of 84.77%, a macro-average F1-score of 0.80, and a macro-average precision of 0.91. The performance of the PSO-optimized CNN-SVM model was benchmarked against traditional machine learning (ML) and deep learning (DL) methods, which demonstrated mean accuracies between 48 and 72%. The proposed hybrid model significantly surpasses these conventional approaches, establishing its superiority in classification accuracy and reliability. The results highlight the proposed model's reliability as a noninvasive diagnostic solution, offering considerable upside for enhancing early brain tumor detection and aiding in treatment planning. © The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature 2025.

关键词： Convolutional neural networks

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Radar Probing Optimization for Joint Beamforming and UAV Trajectory Design in UAV-Enabled Integrated Sensing and Communication

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IEEE Transactions on Communications 2024年第6期73卷 4469-4485页

作者： Liu, Yaxi Mao, Wencan He, Boxin Huangfu, Wei Huang, Tianyao Zhang, Haijun Long, Keping University Of Science And Technology Beijing Beijing Advanced Innovation Center For Materials Genome Engineering Beijing Engineering And Technology Research Center For Convergence Networks And Ubiquitous Services School Of Computer And Communication Engineering Beijing100083 China University Of Science And Technology Shunde Innovation School Beijing China National Institute Of Informatics Information Systems Architecture Science Research Division Tokyo101-8430 Japan

Unmanned aerial vehicle (UAV)-enabled massive multiple-input-multiple-output (MIMO) integrated sensing and communication (ISAC) is an emerging platform to perform communication and sensing efficiently and flexibly. However, the existing works barely consider the radar probing tasks and neglect the benefits of the dedicated sensing signal. In this paper, we focus on joint optimizations in radar probing tasks, and a novel indicator is introduced, namely radar probing error. Two optimizations in radar probing tasks are established: i) joint transmit beamforming design for large-scale regional radar probing and communication task;ii) joint transmit beamforming and UAV trajectory design for communication enhancement and radar probing task. For the former task, we adopt both communication and novel sensing precoders to further support the MIMO radar. A semidefinite relaxation is utilized to relax the original non-convex problem, which is proven to be tight. For the latter task, we adopt block coordinate descent to alternately optimize the precoders and UAV trajectory where the fractional programming approach and successive convex approximation are further adopted. Experiment results testify the validation of the proposed methods for radar probing tasks in UAV-enabled MIMO ISAC. Moreover, results show the fundamental trade-off between the dual functions and reveal the effectiveness of the introduced sensing precoder. © 1972-2012 IEEE.

关键词： Unmanned aerial vehicles (UAV)

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