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Methods for Evaluating Medical Tests and Biomarkers

Diagnostic and Prognostic Research 2017年第1期1卷 1-34页

作者： Gowri Gopalakrishna Miranda Langendam Patrick Bossuyt Mariska Leeflang Rob Scholten Anna Noel-Storr James Thomas Iain Marshall Byron Wallace Penny Whiting Clare Davenport Gowri GopalaKrishna Isabel de Salis Sue Mallett Robert Wolff Marie Westwood Jos Kleinen Richard Riley Gary Collins Hans Reitsma Karel Moons Antonia Zapf Katharina Kramer Annika Hoyer Oliver Kuss J. Ensor R. D. Riley J. J. Deeks E. C. Martin Gerta Rücker Martin Schumacher Susanne Steinhauser Joie Ensor Kym Snell Brian Willis Jon Deeks Thomas Debray Lavinia Ferrante di Ruffano Sian Taylor-Phillips Chris Hyde Stuart A. Taylor Gauraang Batnagar Lavinia Ferrante Di Ruffano Farah Seedat Aileen Clarke Sarah Byron Frances Nixon Rebecca Albrow Thomas Walker Carla Deakin Zhivko Zhelev Harriet Hunt Yaling Yang Lucy Abel James Buchanan Thomas Fanshawe Bethany Shinkins Laure Wynants Sabine Van Huffel Jan Verbakel Dirk Timmerman Ben Van Calster Aeliko Zwinderman Jason Oke Jack O’Sullivan Rafael Perera Brian Nicholson Hannah L. Bromley Tracy E. Roberts Adele Francis Denniis Petrie G. Bruce Mann Kinga Malottki Holly Smith Lucinda Billingham Alice Sitch Oke Gerke Mie Holm-Vilstrup Eivind Antonsen Segtnan Ulrich Halekoh Poul Flemming Høilund-Carlsen Bernard G. Francq Jac Dinnes Julie Parkes Walter Gregory Jenny Hewison Peter Selby Doug Altman William Rosenberg Julien Asselineau Paul Perez Aïssatou Paye Emilie Bessede Cécile Proust-Lima Christiana Naaktgeboren Joris de Groot Johannes Reitsma Anne Rutjes Emmanuel Ogundimu Jonathan Cook Yannick Le Manach Yvonne Vergouwe Romin Pajouheshnia Rolf Groenwold Karen Moons Linda Peelen Bavo De Cock Daan Nieboer Ewout W. Steyerberg Micael J. Pencina Jennifer Cooper Nick Parsons Chris Stinton Steve Smith Andy Dickens Rachel Jordan Alexandra Enocson David Fitzmaurice Peymane Adab Charles Boachie Gaj Vidmar Karoline Freeman Martin Connock Rachel Court Carl Moons Jessica Harris Zoe Plummer Barnaby Reeves Chris Rogers Andrew Mumford Kurtis Lee Veerle Verheyden Gianni D. Angelini Gavin J. Murphy Jeremy Huddy Melody Ni George Hanna Department of Clinical Epidemiology Biostatistics & Bioinformatics Academic Medical Center University of Amsterdam Amsterdam The Netherlands Department of Clinical Epidemiology and Biostatistics Academic Medical Center University of Amsterdam Amsterdam Netherlands Cochrane Netherlands Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Utrecht Netherlands Cochrane Dementia and Cognitive Improvement Group University of Oxford Oxford UK EPPI-Centre Department of Social Science University College London London UK Division of Health and Social Care Research King’s College London London UK College of Computer and Information Science Northeastern University Boston USA University Hospitals Bristol NHS Foundation Trust School of Social and Community Medicine Bristol UK Institute of Applied Health Research University of Birmingham Birmingham UK School of Social and Community Medicine University of Bristol Bristol UK Kleijnen Systematic Reviews Ltd York UK Research Institute for Primary Care and Health Sciences Keele University Keele UK Centre for Statistics in Medicine Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences University of Oxford Oxford UK Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Utrecht The Netherlands Cochrane Netherlands University Medical Center Utrecht Utrecht The Netherlands Julius Center for Health Sciences and Primary Care University Medical Center Utrecht 3584 CG Utrecht Netherlands Department of Medical Statistics University Medical Center Göttingen Göttingen Germany Institute for Biometry and Epidemiology German Diabetes Center Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf Germany Manchester Pharmacy School University of Manchester Manchester UK Institute for Medical Biometry and Statistics Faculty of Medicine and Medical Center – University of Freiburg Stefan-Meier-Str. 26 79104 Freiburg Germany

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Author Correction: Longitudinal development of the human white matter structural connectome and its association with brain transcriptomic and cellular architecture

Communications biology

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Communications biology 2024年第1期7卷 85页

作者： Guozheng Feng Rui Chen Rui Zhao Yuanyuan Li Leilei Ma Yanpei Wang Weiwei Men Jiahong Gao Shuping Tan Jian Cheng Yong He Shaozheng Qin Qi Dong Sha Tao Ni Shu State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research Beijing Normal University Beijing China. BABRI Centre Beijing Normal University Beijing China. Beijing Key Laboratory of Brain Imaging and Connectomics Beijing Normal University Beijing China. College of Life Sciences Beijing Normal University Beijing China. Beijing Key Laboratory of Gene Resource and Molecular Development Beijing China. Center for MRI Research Academy for Advanced Interdisciplinary Studies Peking University Beijing China. Beijing Huilongguan Hospital Peking University Huilongguan Clinical Medical School Beijing China. School of Computer Science and Engineering Beihang University Beijing China. State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research Beijing Normal University Beijing China. taosha@***. State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research Beijing Normal University Beijing China. nshu@***. BABRI Centre Beijing Normal University Beijing China. nshu@***. Beijing Key Laboratory of Brain Imaging and Connectomics Beijing Normal University Beijing China. nshu@***.

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The repertoire of mutational signatures in human cancer (vol 578, pg 94, 2020)

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NATURE 2023年第7948期614卷 E41-E41页

作者： Alexandrov, Ludmil B. Kim, Jaegil Haradhvala, Nicholas J. Huang, Mi Ni Ng, Alvin Wei Tian Wu, Yang Boot, Arnoud Covington, Kyle R. Gordenin, Dmitry A. Bergstrom, Erik N. Islam, S. M. Ashiqul Lopez-Bigas, Nuria Klimczak, Leszek J. McPherson, John R. Morganella, Sandro Sabarinathan, Radhakrishnan Wheeler, David A. Mustonen, Ville Getz, Gad Rozen, Steven G. Stratton, Michael R. Department of Cellular and Molecular Medicine Department of Bioengineering Moores Cancer Center University of California San Diego CA USA Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Department of Cellular and Molecular Medicine and Department of Bioengineering University of California San Diego La Jolla CA USA UC San Diego Moores Cancer Center San Diego CA USA University of California San Diego San Diego CA USA Broad Institute of MIT and Harvard Cambridge MA USA Center for Cancer Research Massachusetts General Hospital Boston MA USA Massachusetts General Hospital Boston MA USA Department of Pathology Massachusetts General Hospital Boston MA USA Harvard Medical School Boston MA USA Laboratory for Medical Science Mathematics RIKEN Center for Integrative Medical Sciences Yokohama Japan Computational Biology Program Ontario Institute for Cancer Research Toronto ON Canada Programme in Cancer & Stem Cell Biology Duke-NUS Medical School Singapore Singapore Centre for Computational Biology Duke-NUS Medical School Singapore Singapore Programme in Cancer and Stem Cell Biology Duke-NUS Medical School Singapore Singapore Programme in Cancer and Stem Cell Biology Centre for Computational Biology Duke-NUS Medical School Singapore Singapore SingHealth Duke-NUS Institute of Precision Medicine National Heart Centre Singapore Singapore Singapore Cancer Science Institute of Singapore National University of Singapore Singapore Singapore Institute of Molecular and Cell Biology Singapore Singapore Laboratory of Cancer Epigenome Division of Medical Science National Cancer Centre Singapore Singapore Singapore Duke-NUS Medical School Singapore Singapore Human Genome Sequencing Center Baylor College of Medicine Houston TX USA Dan L. Duncan Cancer Center Baylor College of Medicine Houston TX USA Department of Molecular and Human Genetics Baylor College of Medicine Houston TX USA Genome Integrity and Structural Biology Laboratory National Ins

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Genomic basis for RNA alterations in cancer (vol 578, pg 129, 2020)

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NATURE 2023年第7948期614卷 E37-E37页

作者： Calabrese, Claudia Davidson, Natalie R. Demircioglu, Deniz Fonseca, Nuno A. He, Yao Lehmann, Kjong-Van Liu, Fenglin Shiraishi, Yuichi Soulette, Cameron M. Urban, Lara Greger, Liliana Li, Siliang Liu, Dongbing Perry, Marc D. Xiang, Qian Zhang, Fan Zhang, Junjun Bailey, Peter Erkek, Serap Hoadley, Katherine A. Hou, Yong Huska, Matthew R. Kilpinen, Helena Korbel, Jan O. Marin, Maximillian G. Markowski, Julia Nandi, Tannistha Pan-Hammarstrom, Qiang Pedamallu, Chandra Sekhar Siebert, Reiner Stark, Stefan G. Su, Hong Tan, Patrick Waszak, Sebastian M. Yung, Christina Zhu, Shida Awadalla, Philip Creighton, Chad J. Meyerson, Matthew Ouellette, B. F. Francis Wu, Kui Yang, Huanming Brazma, Alvis Brooks, Angela N. Goke, Jonathan Ratsch, Gunnar Schwarz, Roland F. Stegle, Oliver Zhang, Zemin European Molecular Biology Laboratory European Bioinformatics Institute Hinxton UK European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK Genome Biology Unit European Molecular Biology Laboratory (EMBL) Heidelberg Germany CIBIO/InBIO - Research Center in Biodiversity and Genetic Resources Universidade do Porto Vairão Portugal Berlin Institute for Medical Systems Biology Max Delbruck Center for Molecular Medicine Berlin Germany German Cancer Consortium (DKTK) partner site Berlin Germany German Cancer Research Center (DKFZ) Heidelberg Germany Berlin Institute for Medical Systems Biology Max Delbrück Center for Molecular Medicine Berlin Germany German Cancer Consortium (DKTK) Partner site Berlin Berlin Germany European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany Division of Computational Genomics and Systems Genetics German Cancer Research Center (DKFZ) Heidelberg Germany ETH Zurich Zurich Switzerland Memorial Sloan Kettering Cancer Center New York NY USA Weill Cornell Medical College New York NY USA SIB Swiss Institute of Bioinformatics Lausanne Switzerland University Hospital Zurich Zurich Switzerland Computational Biology Center Memorial Sloan Kettering Cancer Center New York NY USA Department of Biology ETH Zurich Zürich Switzerland Department of Computer Science ETH Zurich Zurich Switzerland Korea University Seoul South Korea Computational and Systems Biology Program Memorial Sloan Kettering Cancer Center New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine New York NY USA National University of Singapore Singapore Singapore Genome Institute of Singapore Singapore Singapore Computational and Systems Biology Genome Institute of Singap

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The evolutionary history of 2,658 cancers (vol 578, pg 122, 2020)

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NATURE 2023年第7948期614卷 E42-E42页

作者： Gerstung, Moritz Jolly, Clemency Leshchiner, Ignaty Dentro, Stefan C. Gonzalez, Santiago Rosebrock, Daniel Mitchell, Thomas J. Rubanova, Yulia Anur, Pavana Yu, Kaixian Tarabichi, Maxime Deshwar, Amit Wintersinger, Jeff Kleinheinz, Kortine Vazquez-Garcia, Ignacio Haase, Kerstin Jerman, Lara Sengupta, Subhajit Macintyre, Geoff Malikic, Salem Donmez, Nilgun Livitz, Dimitri G. Cmero, Marek Demeulemeester, Jonas Schumacher, Steven Fan, Yu Yao, Xiaotong Lee, Juhee Schlesner, Matthias Boutros, Paul C. Bowtell, David D. Zhu, Hongtu Getz, Gad Imielinski, Marcin Beroukhim, Rameen Sahinalp, S. Cenk Ji, Yuan Peifer, Martin Markowetz, Florian Mustonen, Ville Yuan, Ke Wang, Wenyi Morris, Quaid D. Spellman, Paul T. Wedge, David C. Van Loo, Peter European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany Wellcome Sanger Institute Cambridge UK Genome Biology Unit European Molecular Biology Laboratory (EMBL) Heidelberg Germany University of Ljubljana Ljubljana Slovenia The Francis Crick Institute London UK Big Data Institute University of Oxford Oxford UK Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Big Data Institute Li Ka Shing Centre University of Oxford Oxford UK University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Department of Applied Mathematics and Theoretical Physics Centre for Mathematical Sciences University of Cambridge Cambridge UK Department of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York NY USA Department of Statistics Columbia University New York NY USA Department of Haematology University of Cambridge Cambridge UK University of Leuven Leuven Belgium Broad Institute of MIT and Harvard Cambridge MA USA Center for Cancer Research Massachusetts General Hospital Charlestown MA USA Department of Pathology Massachusetts General Hospital Boston MA USA Harvard Medical School Boston MA USA Center for Cancer Research Massachusetts General Hospital Boston MA USA Dana-Farber Cancer Institute Boston MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Oxford NIHR Biomedical Research Centre Oxford UK Oxford NIHR Biomedical Research Centre University of Oxford Oxford UK University of Toronto Toronto Ontario Canada Vector Institute Toronto Ontario Canada Vector Institute Toronto ON Canada Department of Computer Science University of Toronto Toronto ON Canada Ontario Institute for Cancer Research Toronto Ontario Canada University of California Los Angeles

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Patterns of somatic structural variation in human cancer genomes (vol 578, pg 112, 2020)

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NATURE 2023年第7948期614卷 E38-E38页

作者： Li, Yilong Roberts, Nicola D. Wala, Jeremiah A. Shapira, Ofer Schumacher, Steven E. Kumar, Kiran Khurana, Ekta Waszak, Sebastian Korbel, Jan O. Haber, James E. Imielinski, Marcin Weischenfeldt, Joachim Beroukhim, Rameen Campbell, Peter J. Cancer Genome Project Wellcome Trust Sanger Institute Hinxton UK Totient Inc Cambridge MA USA Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Department of Haematology University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Korea Advanced Institute of Science and Technology Daejeon South Korea Department of Zoology Genetics and Physical Anthropology University of Santiago de Compostela Santiago de Compostela Spain Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) University of Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) University of Vigo Vigo Spain Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain Department of Zoology Genetics and Physical Anthropology (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) Universidade de Vigo Vigo Spain The Broad Institute of Harvard and MIT Cambridge MA USA Bioinformatics and Integrative Genomics Harvard University Cambridge MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Harvard Medical School Boston MA USA Massachusetts General Hospital Center for Cancer Research Charlestown MA USA Dana-Farber Cancer Institute Boston MA USA Department of Biostatistics and Computational Biology Dana-Farber Cancer Institute and Harvard Medical School Boston MA USA Weill Cornell Medical College New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine Ne

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The Brain Tumor Segmentation (BraTS) Challenge: Local Synthesis of Healthy Brain Tissue via Inpainting

arXiv

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arXiv 2023年

作者： Kofler, Florian Steinbauer, Felix Meissen, Felix Graf, Robert Ehrlich, Stefan K. Reinke, Annika Oswald, Eva Waldmannstetter, Diana Hoelzl, Florian Horvath, Izabela Turgut, Oezguen Shit, Suprosanna Bukas, Christina Yang, Kaiyuan Paetzold, Johannes C. de da Rosa, Ezequiel Mekki, Isra Vinayahalingam, Shankeeth Kassem, Hasan Zhang, Juexin Chen, Ke Weng, Ying Durrer, Alicia Cattin, Philippe C. Wolleb, Julia Sadique, M.S. Rahman, M.M. Farzana, W. Temtam, A. Iftekharuddin, K.M. Adewole, Maruf Anwar, Syed Muhammad Baid, Ujjwal Janas, Anastasia Kazerooni, Anahita Fathi LaBella, Dominic Bran Li, Hongwei Moawad, Ahmed W. Conte, Gian-Marco Farahani, Keyvan Eddy, James Sheller, Micah Pati, Sarthak Karagyris, Alexandros Aristizabal, Alejandro Bergquist, Timothy Chung, Verena Shinohara, Russell Takeshi Dako, Farouk Wiggins, Walter Reitman, Zachary Wang, Chunhao Liu, Xinyang Jiang, Zhifan Johanson, Elaine Meier, Zeke Familiar, Ariana Davatzikos, Christos Freymann, John Kirby, Justin Bilello, Michel Fathallah-Shaykh, Hassan M. Wiest, Roland Kirschke, Jan Colen, Rivka R. Kotrotsou, Aikaterini Lamontagne, Pamela Marcus, Daniel Milchenko, Mikhail Nazeri, Arash Weber, Marc-André Mahajan, Abhishek Mohan, Suyash Mongan, John Hess, Christopher Cha, Soonmee Villanueva-Meyer, Javier Colak, Errol Crivellaro, Priscila Jakab, Andras Fatade, Abiodun Omidiji, Olubukola Akinola Lagos, Rachel Olatunji, O.O. Khanna, Goldey Kirkpatrick, John Alonso-Basanta, Michelle Rashid, Arif Bornhorst, Miriam Nabavizadeh, Ali Lepore, Natasha Palmer, Joshua Porras, Antonio Albrecht, Jake Anazodo, Udunna Aboian, Mariam Calabrese, Evan Rudie, Jeffrey David Linguraru, Marius George Iglesias, Juan Eugenio Van Leemput, Koen Bakas, Spyridon Wiestler, Benedikt Ezhov, Ivan Piraud, Marie Menze, Bjoern H. Helmholtz AI Germany Technical University of Munich Germany Helmholtz Munich Germany Klinikum Rechts der Isar Munich Germany SETLabs Research GmbH Healthcare Technologies Munich Germany Heidelberg Division of Intelligent Medical Systems Germany Heidelberg HI Helmholtz Imaging Germany Institute of Clinical Neuroimmunology Faculty of Medicine Ludwig Maximilian University Munich Germany University of Zurich Switzerland Helmholtz Research Center Munich Germany Imperial College London United Kingdom Icometrix Leuven Belgium Department of Oral and Maxillofacial Surgery Radboudumc Netherlands Department of Artificial Intelligence Radboud University Netherlands MLCommons University of Nottingham Ningbo China Ningbo315100 China Center for medical Image Analysis and Navigation Department of Biomedical Engineering University of Basel Allschwil Switzerland Old Dominion University NorfolkVA23529 United States Lab Crestview Radiology Lagos Nigeria Children's National Hospital WashingtonDC United States George Washington University WashingtonDC United States University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Yale University New HavenCT United States Children's Hospital of Philadelphia University of Pennsylvania PhiladelphiaPA United States Duke University Medical Center Department of Radiation Oncology United States Athinoula A Martinos Center for Biomedical Imaging Massachusetts General Hospital BostonMA United States Department of Neuroradiology Technical University of Munich Munich Germany Mercy Catholic Medical Center DarbyPA United States Department of Radiology Mayo Clinic RochesterMN United States Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD20814 U

A myriad of algorithms for the automatic analysis of brain MR images is available to support clinicians in their decision-making. For brain tumor patients, the image acquisition time series typically starts with an already pathological scan. This poses problems, as many algorithms are designed to analyze healthy brains and provide no guarantee for images featuring lesions. Examples include but are not limited to algorithms for brain anatomy parcellation, tissue segmentation, and brain extraction. To solve this dilemma, we introduce the BraTS inpainting challenge. Here, the participants explore inpainting techniques to synthesize healthy brain scans from lesioned ones. The following manuscript contains the task formulation, dataset, and submission procedure. Later, it will be updated to summarize the findings of the challenge. The challenge is organized as part of the ASNR-BraTS MICCAI challenge. Copyright © 2023, The Authors. All rights reserved.

关键词： Magnetic resonance imaging

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Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)

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NATURE COMMUNICATIONS 2022年第1期13卷 1-1页

作者： Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi

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Mineral detection of neutrinos and dark matter. A whitepaper

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Physics of the Dark Universe 2023年 41卷

作者： Baum, Sebastian Stengel, Patrick Abe, Natsue Acevedo, Javier F. Araujo, Gabriela R. Asahara, Yoshihiro Avignone, Frank Balogh, Levente Baudis, Laura Boukhtouchen, Yilda Bramante, Joseph Breur, Pieter Alexander Caccianiga, Lorenzo Capozzi, Francesco Collar, Juan I. Ebadi, Reza Edwards, Thomas Eitel, Klaus Elykov, Alexey Ewing, Rodney C. Freese, Katherine Fung, Audrey Galelli, Claudio Glasmacher, Ulrich A. Gleason, Arianna Hasebe, Noriko Hirose, Shigenobu Horiuchi, Shunsaku Hoshino, Yasushi Huber, Patrick Ido, Yuki Igami, Yohei Ishikawa, Norito Itow, Yoshitaka Kamiyama, Takashi Kato, Takenori Kavanagh, Bradley J. Kawamura, Yoji Kazama, Shingo Kenney, Christopher J. Kilminster, Ben Kouketsu, Yui Kozaka, Yukiko Kurinsky, Noah A. Leybourne, Matthew Lucas, Thalles McDonough, William F. Marshall, Mason C. Mateos, Jose Maria Mathur, Anubhav Michibayashi, Katsuyoshi Mkhonto, Sharlotte Murase, Kohta Naka, Tatsuhiro Oguni, Kenji Rajendran, Surjeet Sakane, Hitoshi Sala, Paola Scholberg, Kate Semenec, Ingrida Shiraishi, Takuya Spitz, Joshua Sun, Kai Suzuki, Katsuhiko Tanin, Erwin H. Vincent, Aaron Vladimirov, Nikita Walsworth, Ronald L. Watanabe, Hiroko Stanford Institute for Theoretical Physics Department of Physics Stanford University Stanford 94305 CA United States Istituto Nazionale di Fisica Nucleare Sezione di Ferrara via Giuseppe Saragat 1 Ferrara I-44122 Italy Mantle Drilling Promotion Office Japan Agency for Marine-Earth Science and Technology (JAMSTEC) Kanagawa Yokohama 236-0001 Japan SLAC National Accelerator Laboratory Stanford University 2575 Sand Hill Road Menlo Park 94025 CA United States Department of Physics University of Zurich Winterthurerstrasse 190 Zurich CH-8057 Switzerland Department of Earth and Environmental Sciences Graduate School of Environmental Studies Nagoya University Furo-cho Chikusa-ku Nagoya 464-8601 Japan Department of Physics and Astronomy University of South Carolina Columbia 29208 SC United States Mechanical and Materials Engineering Queen's University 130 Stuart Street Kingston K7L 2V9 ON Canada Department of Physics Engineering Physics and Astronomy Queen's University 64 Bader Lane KingstonOntario K7L 2S8 Canada Perimeter Institute for Theoretical Physics Waterloo N2J 2W9 ON Canada Istituto Nazionale di Fisica Nucleare Sezione di Milano Via Celoria 16 Milan Italy Dipartimento di Scienze Fisiche e Chimiche Università degli Studi dell'Aquila L'Aquila 67100 Italy Department of Physics University of Chicago Chicago 60637 IL United States Department of Physics University of Maryland College Park 20742 MD United States Quantum Technology Center University of Maryland College Park 20742 MD United States The William H. Miller III Department of Physics and Astronomy The Johns Hopkins University Baltimore 21218 MD United States Institute for Astroparticle Physics Karlsruhe Institute of Technology Karlsruhe 76021 Germany Earth and Planetary Sciences Stanford University Stanford 94305-2115 CA United States Texas Center for Cosmology and Astroparticle Physics Weinberg Institute for Theoretical Physics Department of Physics The University of

Minerals are solid state nuclear track detectors — nuclear recoils in a mineral leave latent damage to the crystal structure. Depending on the mineral and its temperature, the damage features are retained in the material from minutes (in low-melting point materials such as salts at a few hundred °C) to timescales much larger than the 4.5Gyr-age of the Solar System (in refractory materials at room temperature). The damage features from the O(50)MeV fission fragments left by spontaneous fission of ²³⁸U and other heavy unstable isotopes have long been used for fission track dating of geological samples. Laboratory studies have demonstrated the readout of defects caused by nuclear recoils with energies as small as O(1)keV. This whitepaper discusses a wide range of possible applications of minerals as detectors for E_R≳O(1)keV nuclear recoils: Using natural minerals, one could use the damage features accumulated over O(10)Myr–O(1)Gyr to measure astrophysical neutrino fluxes (from the Sun, supernovae, or cosmic rays interacting with the atmosphere) as well as search for Dark Matter. Using signals accumulated over months to few-years timescales in laboratory-manufactured minerals, one could measure reactor neutrinos or use them as Dark Matter detectors, potentially with directional sensitivity. Research groups in Europe, Asia, and America have started developing microscopy techniques to read out the O(1)–O(100)nm damage features in crystals left by O(0.1)–O(100)keV nuclear recoils. We report on the status and plans of these programs. The research program towards the realization of such detectors is highly interdisciplinary, combining geoscience, material science, applied and fundamental physics with techniques from quantum information and Artificial Intelligence. © 2023 Elsevier B.V.

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Body appreciation around the world: Measurement invariance of the Body Appreciation Scale-2 (BAS-2) across 65 nations, 40 languages, gender identities, and age

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Body image 2023年 46卷 449-466页

作者： Viren Swami Ulrich S Tran Stefan Stieger Toivo Aavik Hamed Abdollahpour Ranjbar Sulaiman Olanrewaju Adebayo Reza Afhami Oli Ahmed Annie Aimé Marwan Akel Hussam Al Halbusi George Alexias Khawla F Ali Nursel Alp-Dal Anas B Alsalhani Sara Álvares-Solas Ana Carolina Soares Amaral Sonny Andrianto Trefor Aspden Marios Argyrides John Jamir Benzon R Aruta Stephen Atkin Olusola Ayandele Migle Baceviciene Radvan Bahbouh Andrea Ballesio David Barron Ashleigh Bellard Sóley Sesselja Bender Kerime Derya Beydağ Gorana Birovljević Marie-Ève Blackburn Teresita Borja-Alvarez Joanna Borowiec Miroslava Bozogáňová Solfrid Bratland-Sanda Matthew H E M Browning Anna Brytek-Matera Marina Burakova Yeliz Çakır-Koçak Pablo Camacho Vittorio Emanuele Camilleri Valentina Cazzato Silvia Cerea Apitchaya Chaiwutikornwanich Trawin Chaleeraktrakoon Tim Chambers Qing-Wei Chen Xin Chen Chin-Lung Chien Phatthanakit Chobthamkit Bovornpot Choompunuch Emilio J Compte Jennifer Corrigan Getrude Cosmas Richard G Cowden Kamila Czepczor-Bernat Marcin Czub Wanderson Roberto da Silva Mahboubeh Dadfar Simon E Dalley Lionel Dany Jesus Alfonso D Datu Pedro Henrique Berbert de Carvalho Gabriel Lins de Holanda Coelho Avila Odia S De Jesus Sonia Harzallah Debbabi Sandesh Dhakal Francesca Di Bernardo Donka D Dimitrova Jacinthe Dion Barnaby Dixson Stacey M Donofrio Marius Drysch Hongfei Du Angel M Dzhambov Claire El-Jor Violeta Enea Mehmet Eskin Farinaz Farbod Lorleen Farrugia Leonie Fian Maryanne L Fisher Michał Folwarczny David A Frederick Matthew Fuller-Tyszkiewicz Adrian Furnham Antonio Alías García Shulamit Geller Marta Ghisi Alireza Ghorbani Maria Angeles Gomez Martinez Sarah Gradidge Sylvie Graf Caterina Grano Gyöngyvér Gyene Souheil Hallit Motasem Hamdan Jonathan E Handelzalts Paul H P Hanel Steven R Hawks Issa Hekmati Mai Helmy Tetiana Hill Farah Hina Geraldine Holenweger Martina Hřebíčková Olasupo Augustine Ijabadeniyi Asma Imam Başak İnce Natalia Irrazabal Rasa Jankauskiene Ding-Yu Jiang Micaela Jiménez-Borja Verónica Jiménez-Borja Evan M Johnson Veljko Jov School of Psychology and Sport Science Anglia Ruskin University Cambridge United Kingdom Centre for Psychological Medicine Perdana University Kuala Lumpur Malaysia. Electronic address: viren.swami@aru.ac.uk. Department of Cognition Emotion and Methods in Psychology Faculty of Psychology University of Vienna Vienna Austria. Department of Psychology and Psychodynamics Karl Landsteiner University of Health Sciences Krems an der Donau Austria. Institute of Psychology University of Tartu Tartu Estonia. Department of Psychology Koç University Istanbul Turkiye. Department of Psychology and Behavioural Studies Ekiti State University Ado-Ekiti Nigeria. Department of Art Studies Tarbiat Modares University Tehran Iran. Department of Psychology University of Chittagong Chattogram Bangladesh. Department of Psychoeducation and Psychology Université du Québec en Outaouais Saint-Jérôme Canada. INSPECT-LB: National Institute of Public Health Clinical Epidemiology and Toxicology Beirut Lebanon School of Pharmacy Lebanese International University Beirut Lebanon. Department of Management Ahmed Bin Mohammad Military College Doha Qatar. Faculty of Psychology Panteion University of Social and Political Sciences Athens Greece. Royal College of Surgeons Ireland-Bahrain Adliya Bahrain. Department of Midwifery Faculty of Health Sciences Munzur University Tunceli Turkiya. Department of Oral Medicine and Diagnostic Sciences Vision College of Dentistry and Nursing Vision Colleges Riyadh Saudi Arabia. Facultad de Ciencias de la Vida Universidad Regional Amazónica Ikiam Muyuna Ecuador. Federal Institute of Education Science and Technology of Southeast Minas Gerais Barbacena Brazil. Department of Psychology Universitas Islam Indonesia Yogyakarta Indonesia. Department of Psychology Aberystwyth University Ceredigion United Kingdom. Department of Psychology Neapolis University Pafos Paphos Cyprus. Department of Psychology De La Salle University Phillippines. Department of Gen

The Body Appreciation Scale-2 (BAS-2) is a widely used measure of a core facet of the positive body image construct. However, extant research concerning measurement invariance of the BAS-2 across a large number of nations remains limited. Here, we utilised the Body Image in Nature (BINS) dataset - with data collected between 2020 and 2022 - to assess measurement invariance of the BAS-2 across 65 nations, 40 languages, gender identities, and age groups. Multi-group confirmatory factor analysis indicated that full scalar invariance was upheld across all nations, languages, gender identities, and age groups, suggesting that the unidimensional BAS-2 model has widespread applicability. There were large differences across nations and languages in latent body appreciation, while differences across gender identities and age groups were negligible-to-small. Additionally, greater body appreciation was significantly associated with higher life satisfaction, being single (versus being married or in a committed relationship), and greater rurality (versus urbanicity). Across a subset of nations where nation-level data were available, greater body appreciation was also significantly associated with greater cultural distance from the United States and greater relative income inequality. These findings suggest that the BAS-2 likely captures a near-universal conceptualisation of the body appreciation construct, which should facilitate further cross-cultural research.

关键词： Body appreciation Body appreciation Scale-2 (BAS-2) Cross-cultural Measurement invariance Multi-group confirmatory factor analysis (MG-CFA) Psychometrics Structural analysis

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