Herein,a novel interference-free surface-enhanced Raman spectroscopy(SERS)strategy based on magnetic nanoparticles(MNPs)and aptamer-driven assemblies was proposed for the ultrasensitive detection of histamine.A core-s...
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Herein,a novel interference-free surface-enhanced Raman spectroscopy(SERS)strategy based on magnetic nanoparticles(MNPs)and aptamer-driven assemblies was proposed for the ultrasensitive detection of histamine.A core-satellite SERS aptasensor was constructed by combining aptamer-decorated Fe_(3)O_(4)@Au MNPs(as the recognize probe for histamine)and complementary DNA-modified silver nanoparticles carrying 4-mercaptobenzonitrile(4-MBN)(Ag@4-MBN@Ag-c-DNA)as the SERS signal probe for the indirect detection of *** an applied magnetic field in the absence of histamine,the assembly gave an intense Raman signal at“Raman biological-silent”region due to *** the presence of histamine,the Ag@4-MBN@Ag-c-DNA SERS-tag was released from the Fe_(3)O_(4)@Au MNPs,thus decreasing the SERS *** optimal conditions,an ultra-low limit of detection of 0.65×10^(-3)ng/mL and a linear range 10^(-2)-10^5 ng/mL on the SERS aptasensor were *** histamine content in four food samples were analyzed using the SERS aptasensor,with the results consistent with those determined by high performance liquid *** present work highlights the merits of indirect strategies for the ultrasensitive and highly selective SERS detection of small biological molecules in complex matrices.
Two-dimensional(2D)MoB metal borides(MoB MBene)have attracted much attention due to their fascinating properties and functional *** far,work on the synthesis of 2D MoB nanosheets by acid or alkaline etching of MoAlB h...
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Two-dimensional(2D)MoB metal borides(MoB MBene)have attracted much attention due to their fascinating properties and functional *** far,work on the synthesis of 2D MoB nanosheets by acid or alkaline etching of MoAlB has not been very *** has been proposed that the 2D MoB MBene may be fabricated by chemical etching of a Mo_(2)AlB_(2) precursor,but further investigations were not performed possibly due to the difficult preparation of the metastable Mo_(2)AlB_(2) compound at high temperatures by solid-state ***,we report on the successful synthesis of the Mo_(2)AlB_(2) compound and 2D MoB nanosheets by the deintercalation of Al from MoAlB through a ZnCl_(2) molten salt etching approach at relatively low *** influence of etching temperature,etching time,and starting mixtures on the formation of desirable phases have been investigated.A pure Mo_(2)AlB_(2) compound was synthesized at temperatures below 600℃,while the 2D MoB MBene nanosheets were obtained at 700℃through the molten salt etching of *** addition,the present work further confirms that the MoB MBene can be prepared by etching the as-synthesized Mo_(2)AlB_(2) precursor in LiF–HCl *** work demonstrates that the molten salt etching is an effective method to prepare 2D MoB MBene.
This paper considers the problem of estimating unknown sparse time-varying signals for stochastic dynamic *** deal with the challenges of extensive sparsity,we resort to the compressed sensing method and propose a com...
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This paper considers the problem of estimating unknown sparse time-varying signals for stochastic dynamic *** deal with the challenges of extensive sparsity,we resort to the compressed sensing method and propose a compressed Kalman filter(KF)*** algorithm first compresses the original high-dimensional sparse regression vector via the sensing matrix and then obtains a KF estimate in the compressed low-dimensional ***,the original high-dimensional sparse signals can be well recovered by a reconstruction *** ensure stability and establish upper bounds on the estimation errors,we introduce a compressed excitation condition without imposing independence or stationarity on the system signal,and therefore suitable for feedback *** further present the performance of the compressed KF ***,we show that the mean square compressed tracking error matrix can be approximately calculated by a linear deterministic difference matrix equation,which can be readily evaluated,analyzed,and ***,a numerical example demonstrates that our algorithm outperforms the standard uncompressed KF algorithm and other compressed algorithms for estimating high-dimensional sparse signals.
Epistasis is a ubiquitous phenomenon in genetics,and is considered to be one of main factors in current efforts to unveil missing heritability of complex *** data is crucial for evaluating epistasis detection tools in...
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Epistasis is a ubiquitous phenomenon in genetics,and is considered to be one of main factors in current efforts to unveil missing heritability of complex *** data is crucial for evaluating epistasis detection tools in genome-wide association studies(GWAS).Existing simulators normally suffer from two limitations:absence of support for high-order epistasis models containing multiple single nucleotide polymorphisms(SNPs),and inability to generate simulation SNP data *** this study,we proposed a simulator SimHOEPI,which is capable of calculating penetrance tables of high-order epistasis models depending on either prevalence or heritability,and uses a resampling strategy to generate simulation data *** of SimHOEPI are the preservation of realistic minor allele frequencies in sampling data,the accurate calculation and embedding of high-order epistasis models,and acceptable simulation time.A series of experiments were carried out to verify these properties from different *** results show that SimHOEPI can generate simulation SNP data independently with high-order epistasis models,implying that it might be an alternative simulator for GWAS.
Trifunctional Cu-mesh/Cu_(2)O@FeO nanoarrays heterostructure is designed and fabricated by integrating CuCu_(2)O@FeO nanoarrays onto Cu-mesh(CM)via an in situ growth and phase transformation *** is successfully applie...
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Trifunctional Cu-mesh/Cu_(2)O@FeO nanoarrays heterostructure is designed and fabricated by integrating CuCu_(2)O@FeO nanoarrays onto Cu-mesh(CM)via an in situ growth and phase transformation *** is successfully applied to efficiently mitigate the antibiotic pollution,including degradation of antibiotics,inactivation of antibiotic-resistant bacteria(ARB),and damage of antibiotics resistance genes(ARGs).Under visible-light irradiation,CM/CuCu_(2)O@FeO nanoarrays exhibit a superior degradation efficiency on antibiotics(e.g.,up to 99%in 25 min for tetracycline hydrochloride,TC),due to the generated reactive oxygen species(ROS),especially the dominant·O^(2−).It can fully inactivate ***(HB101)with initial number of~108 CFU mL^(−1) in 10 min,which is mainly attributed to the synergistic effects of 1D nanostructure,dissolved metal ions,and generated ***,it is able to damage ARGs after 180 min of photodegradation,including tetA(vs TC)of 3.3 log 10,aphA(vs kanamycin sulfate,KAN)of 3.4 log 10,and tnpA(vs ampicillin,AMP)of 4.4 log 10,*** work explores a green way for treating antibiotic pollution under visible light.
Extracting the sea area of Marine floating raft culture is contributed to the rational use of aquaculture resources. The availability of remote sensing technology can dynamically detect aquaculture rafts. As a classic...
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Conical worm gearing is a new type of worm gearing composed of a conical worm and a conical worm wheel, which differs from ordinary cylindrical worm gearing in that the working helical surface of the worm in the conic...
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This article investigates the finite-time synchronization (FTS) for inertial memristive neural networks (IMNNs) with time-delays by the aperiodically intermittent control approach. Compared with the reduced-order meth...
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This paper proposes an innovative column composed of a core column(including both reinforced concrete(RC)and plain concrete(PC)columns)and a prefabricated textile-reinforced fine concrete(TRC)*** study the confinement...
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This paper proposes an innovative column composed of a core column(including both reinforced concrete(RC)and plain concrete(PC)columns)and a prefabricated textile-reinforced fine concrete(TRC)*** study the confinement properties of TRC shells on this novel type of concrete column,20 circular specimens,including 12 PC columns and 8 RC columns,were prepared for axial compressive *** key parameters,including the column size,reinforcing ratio of the carbon textile,concrete strength,and stirrup spacing,were *** results indicated that the compressive properties of the columns were improved by increasing the reinforcing ratio of the textile *** the case of TRC-confined PC columns,the maximum improvement in the peak load was 56.3%,and for TRC-confined RC columns,the maximum improvement was 60.2%.Based on the test results,an analytical model that can be used to calculate the stress–strain curves of prefabricated TRC shell-confined concrete columns has been *** calculated curves predicted by the proposed model agreed well with the test results.
This article investigates distributed adaptive leader-following consensus tracking optimal control problem for nonlinear multiagent systems (MASs) subject to unknown nonlinearities and uncertain external disturbances....
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