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Smart photonic wristband for pulse wave monitoring

Opto-Electronic science 2024年第12期3卷 12-27页

作者： Renfei Kuang Zhuo Wang Lin Ma Heng Wang Qingming Chen Arnaldo Leal Junior Santosh Kumar Xiaoli Li Carlos Marques Rui Min Center for Cognition and Neuroergonomics State Key Laboratory of Cognitive Neuroscience and LearningBeijing Normal UniversityZhuhai 519087China College of Science Shenyang Aerospace UniversityShenyang 110136China School of Microelectronics Science and Technology Guangdong Provincial Key Laboratory of Optoelectronic Information Processing Chips and SystemsSun Yat-Sen UniversityZhuhai 519082China Graduate Program in Electrical Engineering Federal University of Espírito SantoFernando Ferrari AvenueVitoria 29075-910Brazil Department of Electronics and Communication Engineering Koneru Lakshmaiah Education FoundationVaddeswaramAndhra Pradesh 522302India CICECO-Aveiro Institute of Materials Physics DepartmentUniversity of AveiroAveiro 3810-193Portugal

Real-time acquisition of human pulse signals in daily life is clinically important for cardiovascular disease monitoring and ***,we propose a smart photonic wristband for pulse signal monitoring based on speckle pattern analysis with a polymer optical fiber(POF)integrated into a sports *** different speckle pattern processing algorithms and POFs with different core diameters were *** results indicated that the smart photonic wristband had a high signal-to-noise ratio and low latency,with the measurement error controlled at approximately 3.7%.This optimized pulse signal could be used for further medical diagnosis and was capable of objectively monitoring subtle pulse signal changes,such as the pulse waveform at different positions of Cunkou and pulse waveforms before and after *** the assistance of artificial intelligence(AI),functions such as gesture recognition have been realized through the established prediction model by processing pulse signals,in which the recognition accuracy reaches 95%.Our AI-assisted smart photonic wristband has potential applications for clinical treatment of cardiovascular diseases and home monitoring,paving the way for medical Internet of Things-enabled smart systems.

关键词： smart healthcare specklegram pulse monitoring gesture recognition artificial intelligence wearable sensor

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Emerging contaminants:A One Health perspective

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The Innovation 2024年第4期5卷 140-170,139页

作者： Fang Wang Leilei Xiang Kelvin Sze-Yin Leung Martin Elsner Ying Zhang Yuming Guo Bo Pan Hongwen Sun Taicheng An Guangguo Ying Bryan WBrooks Deyi Hou Damian EHelbling Jianqiang Sun Hao Qiu Timothy MVogel Wei Zhang Yanzheng Gao Myrna JSimpson Yi Luo Scott XChang Guanyong Su Bryan MWong Tzung-May Fu Dong Zhu Karl JJobst Chengjun Ge Frederic Coulon Jean Damascene Harindintwali Xiankui Zeng Haijun Wang Yuhao Fu Zhong Wei Rainer Lohmann Changer Chen Yang Song Concepcion Sanchez-Cid Yu Wang Ali El-Naggar Yiming Yao Yanran Huang Japhet Cheuk-Fung Law Chenggang Gu Huizhong Shen Yanpeng Gao Chao Qin Hao Li Tong Zhang Natàlia Corcoll Min Liu Daniel SAlessi Hui Li Kristian KBrandt Yolanda Pico Cheng Gu Jianhua Guo Jianqiang Su Philippe Corvini Mao Ye Teresa Rocha-Santos Huan He Yi Yang Meiping Tong Weina Zhang Fidèle Suanon Ferdi Brahushi Zhenyu Wang Syed AHashsham Marko Virta Qingbin Yuan Gaofei Jiang Louis A.Tremblay Qingwei Bu Jichun Wu Willie Peijnenburg Edward Topp Xinde Cao Xin Jiang Minghui Zheng Taolin Zhang Yongming Luo Lizhong Zhu Xiangdong Li DamiàBarceló Jianmin Chen Baoshan Xing Wulf Amelung Zongwei Cai Ravi Naidu Qirong Shen Janusz Pawliszyn Yong-guan Zhu Andreas Schaeffer Matthias C.Rillig Fengchang Wu Gang Yu James M.Tiedje State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China University of Chinese Academy of Sciences Beijing 100049China Department of Chemistry Hong Kong Baptist UniversityHong KongChina HKBU Institute of Research and Continuing Education Shenzhen Virtual University ParkShenzhenChina Technical University of Munich TUM School of Natural SciencesInstitute of Hydrochemistry85748 GarchingGermany School of Resources&Environment Northeast Agricultural UniversityHarbin 150030China Climate Air Quality Research UnitSchool of Public Health and Preventive MedicineMonash UniversityMelbourneVICAustralia Faculty of Environmental Science&Engineering Kunming University of Science&TechnologyKunming 650500China Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria College of Environmental Science and EngineeringNankai UniversityTianjin 300350China Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control School of Environmental Science and EngineeringInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Ministry of Education Key Laboratory of Environmental Theoretical Chemistry South China Normal UniversityGuangzhouGuangdong 510006China Department of Environmental Science Baylor UniversityWacoTXUSA Center for Reservoir and Aquatic Systems Research(CRASR) Baylor UniversityWacoTXUSA School of Environment Tsinghua UniversityBeijing 100084China School of Civil and Environmental Engineering Cornell UniversityIthacaNY 14853USA Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province Zhejiang University of TechnologyHangzhou 310014China School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Laboratoire d’Ecologie Microbienne Universite Claude Bernard Lyon 1UMR CNRS 5557UMR INRAE 1418VetAgro Sup69622 VilleurbanneFrance Department of Pla

Environmental pollution is escalating due to rapid global development that often prioritizes human needs over planetary *** global efforts to mitigate legacy pollutants,the continuous introduction of new substances remains a major threat to both people and the *** response,global initiatives are focusing on risk assessment and regulation of emerging contaminants,as demonstrated by the ongoing efforts to establish the UN’s Intergovernmental science-Policy Panel on Chemicals,Waste,and Pollution *** review identifies the sources and impacts of emerging contaminants on planetary health,emphasizing the importance of adopting a One Health *** for monitoring and addressing these pollutants are discussed,underscoring the need for robust and socially equitable environmental policies at both regional and international *** actions are needed to transition toward sustainable pollution management practices to safeguard our planet for future generations.

关键词： pollution planet contaminants

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Reconfigurable Hyperbolic Polaritonics with Correlated Oxide Metasurfaces

Research Square

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Research Square 2021年

作者： Aghamiri, Neda Alsadat Hu, Guangwei Fali, Alireza Zhang, Zhen Li, Jiahan Balendhran, Sivacarendran Walia, Sumeet Sriram, Sharath Edgar, James H. Ramanathan, Shriram Alù, Andrea Abate, Yohannes Department of Physics and Astronomy University of Georgia AthensGA30602 United States Photonics Initiative Advanced Science Research Center City University of New York New YorkNY10031 United States Department of Electrical and Computer Engineering National University of Singapore Kent Ridge Singapore117583 Singapore School of Materials Engineering Purdue University West LafayetteIN47907 United States Tim Taylor Department of Chemical Engineering Kansas State University ManhattanKN 66506 United States School of Physics University of Melbourne ParkvilleVIC3010 Australia School of Engineering RMIT University MelbourneVIC Australia Functional Materials and Microsystems Research Group Micro Nano Research Facility RMIT University MelbourneVIC Australia ARC Centre of Excellence for Transformative Meta-Optical Systems RMIT University MelbourneVIC Australia Physics Program Graduate Center City University of New York New YorkNY10016 United States

Polaritons enable subwavelength confinement and highly anisotropic flows of light over a wide spectral range, holding the promise for applications in modern nanophotonic and optoelectronic devices. However, to fully realize their practical application potential, facile methods enabling nanoscale active control of polaritons are needed. Here, we introduce a hybrid polaritonic-oxide heterostructure platform consisting of van der Waals crystals, such as hexagonal boron nitride (hBN) or alpha-phase molybdenum trioxide (α-MoO3), transferred on nanoscale oxygen vacancy patterns on the surface of prototypical correlated perovskite oxide SmNiO3 (SNO). Using a combination of scanning probe microscopy and infrared nanoimaging techniques, we demonstrate nanoscale real-time reconfigurability of complex hyperbolic phonon polaritons patterned at the nanoscale with unmatched resolution. Hydrogenation and temperature modulation allow spatially localized conductivity modulation of SNO nanoscale patterns, enabling robust real-time modulation and nanoscale reconfiguration of hyperbolic polaritons. Our work paves the way towards nanoscale programmable metasurface engineering as a new paradigm for reconfigurable nanophotonic applications facilitated by a hybrid material platform exploiting extreme light-matter interactions in polaritonic systems. © 2021, CC BY.

关键词： Polariton

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A high quality and quantity hybrid perovskite quantum dots (CsPbX3, X= Cl, Br and I) powders synthesis via ionic displacement

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IOP Conference Series: Earth and Environmental science 2017年第1期100卷

作者： Yuhang Yin Weiling Luan Chengxi Zhang Fuqian Yang Key Laboratory of Pressure Systems and Safety (MOE) School of Mechanical and Power Engineering East China University of Science and Technology Shanghai 200237 P. R. China. Materials Program Department of Chemical and Materials Engineering University of Kentucky Lexington KY 40513 USA.

Recently, all-inorganic perovskites CsPbX3 (X= Cl, Br and I) quantum dots (QDs) have drawn great attentions because of their PL spectra tunable over the whole visible spectral region (400-700 nm) and adjustable bandgap, which revealed a promising potential on the field of photoelectronic devices, such as solar cells, LEDs and sensors. In this paper, CsPbX3 QDs and hybrid QDs, CsPbClxBr3-x and CsPbBrxI3-x were synthesized via one-step and two-step methods comparably. The optical bandgaps of CsPbCl3, CsPbBr3, and CsPbI3, were calculated as 3.08, 2.36, and 1.73eV, respectively, based on the Tauc's equation and UV absorption spectra. Ionic displacement and phase transformation occurred during the mixing process were found based on the monitoring of PL spectra and HRTEM characterization. The long-term stability, dried, high quality and two-dimensional hybrid CsPbBrxI3-x QDs powders could be achieved via the two-step method. Polar solution inductions were used to wash and purify the CsPbX3 QDs, which help obtain of various compositions and well crystallize all-inorganic perovskites QDs powders.

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Application of Emerging Innovations in Microbiome science to Space Development and Settlement systems 73

Application of Emerging Innovations in Microbiome Science to...

引用

73rd International Astronautical Congress, IAC 2022

作者： Nastasi, Nicholas Anderson, Matthew Z. Balasubrahmaniam, Neeraja Bope, Ashleigh Britt, Rodney D. Cochran, Samuel J. Gill, Samuel J. Hegarty, Bridget Lee, Jiyoung Stamps, Blake W. Stickney, Amanda Taylor, Christopher G. Tram, Nguyen K. Van Dusen, John Varaljay, Vanessa A. Weir, Mark H. Horack, John M. Oglesbee, Michael Sullivan, Matthew B. Dannemiller, Karen C. Department of Civil Environmental & Geodetic Engineering Ohio State University ColumbusOH United States Division of Environmental Health Sciences College of Public Health Ohio State University ColumbusOH United States Environmental Sciences Graduate Program Ohio State University ColumbusOH United States Department of Microbiology College of Arts and Sciences Ohio State University ColumbusOH United States Department of Microbial Infection and Immunity Ohio State University ColumbusOH United States Center for Perinatal Research The Abigail Wexner Research Institute Nationwide Children's Hospital Department of Pediatrics Ohio State University ColumbusOH United States Department of Civil and Environmental Engineering Case School of Engineering Case Western Reserve University ClevelandOH United States Department of Food Science and Technology Ohio State University ColumbusOH United States Infectious Diseases Institute Ohio State University ColumbusOH United States Soft Matter Materials Branch Materials and Manufacturing Directorate Air Force Research Laboratory Wright - Patterson AFBOH United States Department of Plant Pathology College of Food Agriculture and Environmental Science Ohio State University ColumbusOH United States Department of Anesthesiology & Pain Medicine Nationwide Children's Hospital ColumbusOH United States Airman Systems Directorate 711th Human Performance Wing Air Force Research Laboratory WPAFBOH United States Sustainability Institute Ohio State University ColumbusOH United States Department of Mechanical and Aerospace Engineering College of Engineering John Glenn College of Public Affairs Ohio State University ColumbusOH United States Department of Veterinary Biosciences College of Veterinary Medicine Ohio State University ColumbusOH United States Center of Microbiome Science Ohio State University ColumbusOH United States

Future human spaceflight beyond low-Earth orbit will bring substantial changes and new requirements to the development of fully sustainable, healthy indoor human environments across a range of gravitational, radiative, and thermal conditions. One key aspect is understanding (and potentially leveraging) microorganisms that must coexist with humans, plants, and animals in enclosed habitats (their microbiota or microbiomes). Modern, genome-resolved microbiome science provides an opportunity to better understand how we can utilize microbes to optimize space missions and protect human health and well-being long-term. Microorganisms will be critical to mission success due to their direct or indirect interactions with 1) humans, 2) other living systems (e.g., plant and animal life as a food source and for experimentation), and 3) the built environment. For example, the human gut microbiome is a complex community that has important implications for human health and performance that include mental health, nutrition intake, and immune system function. The health of plant microbiomes is also critical for sustainable, dependable, and nutritious food production. Humans, plants, and other living systems (e.g., animals used in experimentation) will also shed microbes into the built environment, which may impact human exposure, plant health, system integrity, and planetary protection from microbial contamination in both forward and reverse directions. Microbes from all three systems will interact, resulting in potentially important 'non-linear' system implications that must be understood for the overall long-term sustainability of hardware, crew, and other living systems. This paper discusses recent advances in technology that expand measurement capabilities to ultra-low-biomass samples and now allow for better understanding of microbial taxa, community structure and drivers, and functional capacity, which together will empower microbiome-optimized deep-space human exploration miss

关键词： Bacteria

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Experimentally shock-induced melt veins in basalt: Improving the shock classification of eucrites

arXiv

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arXiv 2022年

作者： Ono, Haruka Kurosawa, Kosuke Niihara, Takafumi Mikouchi, Takashi Tomioka, Naotaka Isa, Junko Kagi, Hiroyuki Matsuzaki, Takuya Sakuma, Hiroshi Genda, Hidenori Sakaiya, Tatsuhiro Kondo, Tadashi Kayama, Masahiro Koike, Mizuho Sano, Yuji Murayama, Masafumi Satake, Wataru Matsui, Takafumi Planetary Exploration Research Center Chiba Institute of Technology 2-17-1 Tsudanuma Narashino Chiba275-0016 Japan Department of Applied Science Okayama University of Science 1-1 Ridaicho Kita-ku Okayama-shi700-0005 Japan The University Museum The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan 200 Monobe Otsu Kochi Nankoku783-8502 Japan Geochemical Research Center Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan Center for Advanced Marine Core Research Kochi University 200 Monobe Otsu Kochi Nankoku783-8502 Japan Research Center for Functional Materials National Institute for Materials Science 1-1 Namiki Ibaraki Tsukuba305-0044 Japan Earth–Life Science Institute Tokyo Institute of Technology 2-12-1 Ookayama Meguro-ku Tokyo152-8550 Japan Department of Earth and Space Science Graduate School of Science Osaka University 1-1 Machikaneyama Osaka Toyonaka560-0043 Japan Department of General Systems Studies Graduate School of Arts and Sciences The Univ. of Tokyo 3-8-1 Komaba Meguro-ku Tokyo153-8902 Japan Earth and Planetary Systems Science Program Graduate School of Advanced Science and Engineering Hiroshima University 1-3-1 Kagamiyama Higashi–Hiroshima Hiroshima739-8526 Japan Institute of Geo-Cosmology Chiba Institute of Technology 2-17-1 Tsudanuma Chiba Narashino275-0016 Japan

Basaltic rocks occur widely on the terrestrial planets and differentiated asteroids, including the asteroid 4 Vesta. We conducted a shock recovery experiment with decaying compressive pulses on a terrestrial basalt at Chiba Institute of Technology, Japan. The sample recorded a range of pressures, and shock physics modeling was conducted to add a pressure scale to the observed shock features. The shocked sample was examined by optical and electron microscopy, electron back-scattered diffractometry, and Raman spectroscopy. We found that localized melting occurs at a lower pressure (~10 GPa) than previously thought (>20 GPa). The shocked basalt near the epicenter represents "shock degree C" of a recently proposed classification scheme for basaltic eucrites and, as such, our results provide a pressure scale for the classification scheme. Finally, we estimated the total fraction of the basaltic eucrites classified as shock degree C to be ~15% by assuming the impact velocity distribution onto Vesta. © 2022, CC BY-NC-SA.

关键词： Basalt

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Breaking Mechanical Holography in Combinatorial Metamaterials

arXiv

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arXiv 2024年

作者： Sirote-Katz, Chaviva Palti, Ofri Spiro, Naomi Kálmán, Tamás Shokef, Yair Department of Biomedical Engineering Tel Aviv University Tel Aviv69978 Israel The Future Scientists Center Alpha Program Tel Aviv Youth University Tel Aviv69978 Israel University of Illinois at Urbana-Champaign UrbanaIL61801 United States Department of Mathematics Institute of Science Tokyo H-214 2-12-1 Ookayama Tokyo Meguro-ku152-8551 Japan Hiroshima University Higashi-Hiroshima Hiroshima739-8526 Japan School of Mechanical Engineering Tel Aviv University Tel Aviv69978 Israel Center for Computational Molecular and Materials Science Tel Aviv University Tel Aviv69978 Israel Center for Physics and Chemistry of Living Systems Tel Aviv University Tel Aviv69978 Israel

Combinatorial mechanical metamaterials are made of anisotropic, flexible blocks, such that multiple metamaterials may be constructed using a single block type, and the system’s response strongly depends on the mutual orientations of the blocks within the lattice. We study a family of possible block types for the square, honeycomb, and cubic lattices. Blocks that are centrally symmetric induce holographic order, such that mechanical compatibility (meaning that blocks do not impede each other’s motion) implies bulk-boundary coupling. With them, one can design a compatible metamaterial that will deform in any desired texture only on part of its boundary. With blocks that break holographic order, we demonstrate how to design the deformation texture on the entire boundary. Correspondingly, the number of compatible holographic metamaterials scales exponentially with the boundary, while in non-holographic cases we show that it scales exponentially with the bulk. © 2024, CC BY.

关键词： Holography

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Marangoni convection-driven laser fountains and waves on free surfaces of liquids

arXiv

引用

arXiv 2021年

作者： Lin, Feng Quraishy, Aamir Nasir Tong, Tian Li, Runjia Yang, Guang Mohebinia, Mohammadjavad Qiu, Yi Vishal, Talari Zhao, Junyi Zhang, Wei Zhong, Hong Zhang, Hang Zhou, Chaofu Tong, Xin Yu, Peng Hu, Jonathan Dong, Suchuan Liu, Dong Wang, Zhiming Schaibley, John R. Bao, Jiming Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China ChengduSichuan610054 China Department of Electrical and Computer Engineering University of Houston HoustonTX77204 United States Department of Physics University of Arizona TucsonAZ85721 United States James C. Wyant College of Optical Sciences University of Arizona TucsonAZ85721 United States Department of Mechanical Engineering University of Houston HoustonTX77204 United States Materials Science and Engineering Program University of Houston HoustonTX77204 United States School of Science Southwest Petroleum University ChengduSichuan610500 China Department of Electrical and Systems Engineering Washington University in St. Louis St. LouisMO63130 United States Department of Electrical & Computer Engineering Baylor University WacoTX76798 United States Department of Mathematics Purdue University West LafayetteIN47907 United States Department of Physics Texas Center for Superconductivity University of Houston HoustonTX77204 United States

It is well accepted that an outward Marangoni convection from a low surface tension region will make the surface depressed. Here, we report that this established perception is only valid for thin liquid films. Using surface laser heating, we show that in deep liquids a laser beam actually pulls up the fluid above the free surface generating fountains with different shapes. Whereas with decreasing liquid depth a transition from fountain to indentation with fountain-in-indentation is observed. Further, high-speed imaging reveals a transient surface process before steady elevation is formed, and this dynamic deformation is subsequently utilized to resonantly excite giant surface waves by a modulated laser beam. Computational fluid dynamics models reveal the underlying flow patterns and quantify the depth-dependent and time-resolved surface deformations. Our discoveries and techniques have upended the century-old perception and opened up a new regime of interdisciplinary research and applications of Marangoni-induced interface phenomena and optocapillary fluidic surfaces - the control of fluids with light. © 2021, CC BY.

关键词： Deformation

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Motorized Macrocycle: A Photo-responsive Host with Switchable and Stereoselective Guest Recognition

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Angewandte Chemie 2021年第29期133卷

作者： Dr. Yue Liu Dr. Qi Zhang Dr. Stefano Crespi Dr. Shaoyu Chen Xiu-Kang Zhang Tian-Yi Xu Chang-Shun Ma Shang-Wu Zhou Zhao-Tao Shi Prof. He Tian Prof. Ben L. Feringa Prof. Da-Hui Qu Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Feringa Nobel Prize Scientist Joint Research Center Frontiers Science Center for Materiobiology and Dynamic Chemistry Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology Shanghai 200237 China Centre for Systems Chemistry Stratingh Institute for Chemistry and Zernike Institute for Advanced Materials University of Groningen Nijenborgh 4 9747 AG Groningen The Netherlands

Designing photo-responsive host–guest systems can provide versatile supramolecular tools for constructing smart systems and materials. We designed photo-responsive macrocyclic hosts, modulated by light-driven molecular rotary motors enabling switchable chiral guest recognition. The intramolecular cyclization of the two arms of a first-generation molecular motor with flexible oligoethylene glycol chains of different lengths resulted in crown-ether-like macrocycles with intrinsic motor function. The octaethylene glycol linkage enables the successful unidirectional rotation of molecular motors, simultaneously allowing the 1:1 host–guest interaction with ammonium salt guests. The binding affinity and stereoselectivity of the motorized macrocycle can be reversibly modulated, owing to the multi-state light-driven switching of geometry and helicity of the molecular motors. This approach provides an attractive strategy to construct stimuli-responsive host–guest systems and dynamic materials.

关键词： capture and release host–guest interactions motorized macrocycles photo-responsiveness stereoselectivity

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A Radial Basis Function Spike Model for Indirect Learning via Integrate-and-Fire Sampling and Reconstruction Techniques

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Advances in Artificial Neural systems 2012年第1期2012卷

作者： X. Zhang G. Foderaro C. Henriquez A. M. J. VanDongen S. Ferrari Laboratory for Intelligent Systems and Control (LISC) Department of Mechanical Engineering and Materials Science Duke University Durham NC 27708 USAduke.edu Department of Biomedical Engineering and Department of Computer Science Duke University Durham NC 27708 USAduke.edu Program in Neuroscience & Behavioral Disorders Duke-NUS Graduate Medical School Singapore Singapore

This paper presents a deterministic and adaptive spike model derived from radial basis functions and a leaky integrate-and-fire sampler developed for training spiking neural networks without direct weight manipulation. Several algorithms have been proposed for training spiking neural networks through biologically-plausible learning mechanisms, such as spike-timing-dependent synaptic plasticity and Hebbian plasticity. These algorithms typically rely on the ability to update the synaptic strengths, or weights, directly, through a weight update rule in which the weight increment can be decided and implemented based on the training equations. However, in several potential applications of adaptive spiking neural networks, including neuroprosthetic devices and CMOS/memristor nanoscale neuromorphic chips, the weights cannot be manipulated directly and, instead, tend to change over time by virtue of the pre- and postsynaptic neural activity. This paper presents an indirect learning method that induces changes in the synaptic weights by modulating spike-timing-dependent plasticity by means of controlled input spike trains. In place of the weights, the algorithm manipulates the input spike trains used to stimulate the input neurons by determining a sequence of spike timings that minimize a desired objective function and, indirectly, induce the desired synaptic plasticity in the network.

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