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arXiv 2024年

作者： de la Rosa, Ezequiel Reyes, Mauricio Liew, Sook-Lei Hutton, Alexandre Wiest, Roland Kaesmacher, Johannes Hanning, Uta Hakim, Arsany Zubal, Richard Valenzuela, Waldo Robben, David Sima, Diana M. Anania, Vincenzo Brys, Arne Meakin, James A. Mickan, Anne Broocks, Gabriel Heitkamp, Christian Gao, Shengbo Liang, Kongming Zhang, Ziji Siddiquee, Md Mahfuzur Rahman Myronenko, Andriy Ashtari, Pooya Van Huffel, Sabine Jeong, Hyun-Su Yoon, Chi-Ho Kim, Chulhong Huo, Jiayu Ourselin, Sebastien Sparks, Rachel Clèrigues, Albert Oliver, Arnau Lladó, Xavier Chalcroft, Liam Pappas, Ioannis Bertels, Jeroen Heylen, Ewout Moreau, Juliette Hatami, Nima Frindel, Carole Qayyum, Abdul Mazher, Moona Puig, Domenec Lin, Shao-Chieh Juan, Chun-Jung Hu, Tianxi Boone, Lyndon Goubran, Maged Liu, Yi-Jui Wegener, Susanne Kofler, Florian Ezhov, Ivan Shit, Suprosanna Hernandez Petzsche, Moritz R. Menze, Bjoern Kirschke, Jan S. Wiestler, Benedikt Department of Quantitative Biomedicine University of Zurich Zurich Switzerland Department of Informatics Technical University Munich Germany Icometrix Leuven Belgium ARTORG Center for Biomedical Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Switzerland University of Bern Bern Switzerland Chan Division of Occupational Science and Occupational Therapy University of Southern California Los AngelesCA United States Stevens Neuroimaging and Informatics Institute Department of Neurology Keck School of Medicine University of Southern California United States University Institute of Diagnostic and Interventional Neuroradiology Inselspital Bern Switzerland University Institute of Diagnostic and Interventional Neuroradiology University Hospital Bern Inselspital University of Bern Bern Switzerland Department of Diagnostic and Interventional neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany Department of Medical Imaging Radboud University Medical Center Institute for Health Sciences Nijmegen Netherlands Deepwise AI Lab Beijing China Beijing University of Posts and Telecommunications Bejing China School of Computing and Augmented Intelligence Arizona State University TempeAZ United States NVIDIA Santa ClaraCA United States STADIUS Center for Dynamical Systems Signal Processing and Data Analytics KU Leuven Leuven Belgium Pohang Korea Republic of School of Biomedical Engineering & Imaging Sciences King’s College London United Kingdom Institute of Computer Vision and Robotics University of Girona Spain Wellcome Centre for Human Neuroimaging University College London London United Kingdom Laboratory of Neuro Imaging Stevens Institute for Neuroimaging and Informatics Keck School of Medicine University of Southern California Los Angeles United States KU Leuven Leuven Belgium CREATIS Université Lyon1 CNRS UMR5220 INSERM U1206 INSA-Lyon Villeurbanne696

Diffusion-weighted MRI (DWI) is essential for stroke diagnosis, treatment decisions, and prognosis. However, image and disease variability hinder the development of generalizable AI algorithms with clinical value. We address this gap by presenting a novel ensemble algorithm derived from the 2022 Ischemic Stroke Lesion Segmentation (ISLES) challenge. ISLES’22 provided 400 patient scans with ischemic stroke from various medical centers, facilitating the development of a wide range of cutting-edge segmentation algorithms by the research community. By assessing them against a hidden test set, we identified strengths, weaknesses, and potential biases. Through collaboration with leading teams, we combined top-performing algorithms into an ensemble model that overcomes the limitations of individual solutions. Our ensemble model combines the individual algorithms’ strengths and achieved superior ischemic lesion detection and segmentation accuracy (median Dice score: 0.82, median lesion-wise F1 score: 0.86) on our internal test set compared to individual algorithms. This accuracy generalized well across diverse image and disease variables. Furthermore, the model excelled in extracting clinical biomarkers like lesion types and affected vascular territories. Notably, in a Turing-like test, neuroradiologists consistently preferred the algorithm’s segmentations over manual expert efforts, highlighting increased comprehensiveness and precision. Validation using a real-world external dataset (N=1686) confirmed the model’s generalizability (median Dice score: 0.82, median lesion-wise F1 score: 0.86). The algorithm’s outputs also demonstrated strong correlations with clinical scores (admission NIHSS and 90-day mRS) on par with or exceeding expert-derived results, underlining its clinical relevance. This study offers two key findings. First, we present an ensemble algorithm that detects and segments ischemic stroke lesions on DWI across diverse scenarios on par with expert (neuro)rad

关键词： Diagnosis

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Straggler mitigation with tiered gradient codes

arXiv

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arXiv 2019年

作者： Sasi, Shanuja Lalitha, V. Aggarwal, Vaneet Sundar Rajan, B. Department of Electrical Communication Engineering Indian Institute of Science Bangalore 560012 India Purdue University Signal Processing and Communications Research Center IIIT Hyderabad School of Industrial Engineering School of Electrical and Computer Engineering Purdue University West LafayetteIN47907 United States

Coding theoretic techniques have been proposed for synchronous Gradient Descent (GD) on multiple servers to mitigate stragglers. These techniques provide the flexibility that the job is complete when any k out of n servers finish their assigned tasks. The task size on each server is found based on the values of k and n. However, it is assumed that all the n jobs are started when the job is requested. In contrast, we assume a tiered system, where we start with n1≥k tasks, and on completion of c tasks, we start n2-n1more tasks. The aim is that as long as k servers can execute their tasks, the job gets completed. This paper exploits the flexibility that not all servers are started at the request time to obtain the achievable task sizes on each server. The task sizes are in general lower than starting all n2tasks at the request times thus helping achieve lower task sizes which helps to reduce both the job completion time and the total server utilization. Copyright © 2019, The Authors. All rights reserved.

关键词： Gradient methods

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Machine learning based Gaussian process regression for fault detection of Biological Systems

Machine learning based Gaussian process regression for fault...

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International Conference on Internet of Things, Embedded Systems and Communications (IINTEC)

作者： Radhia Fezai Majdi Mansouri Nasreddine Bouguila Hazem Nounou Mohamed Nounou Laboratory of Automatic Signal and Image Processing National School of Engineers of Monastir University of Monastir Tunisia Electrical and Computer Engineering Program Texas A&M University at Qatar Doha QATAR Chemical Engineering Program Texas A&M University at Qatar Doha Qatar

ISBN: (数字)9781728151847

ISBN: (纸本)9781728151854

Effective detection of faults in Biological processes is essential to observe the continuity of good functioning of the system under typical circumstances for ensuring safety. Therefore, the first objective of this paper is to develop a machine learning based Gaussian process regression (GPR) technique that can accurately model biological processes and compute the monitored residuals. The second objective is to apply a generalized likelihood ratio test (GLRT) to the evaluated residuals for fault detection purposes. The detection performance of the GPR-based GLRT is evaluated using a biological process representing a Cad System in E. Coli (CSEC) model. The GPR-based GLRT is used to enhance monitoring of the Cad System in E. coli process through monitoring some of the key variables involved in this process, such as enzymes, lysine, and cadaverine.

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Reduced Gaussian process regression for fault detection of chemical processes

Reduced Gaussian process regression for fault detection of c...

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International Conference on Internet of Things, Embedded Systems and Communications (IINTEC)

ISBN: (数字)9781728151847

ISBN: (纸本)9781728151854

In this paper, a reduced Gaussian process regression (RGPR)-based generalized likelihood ratio test (GLRT) is proposed for fault detection in industrial systems. In contrast to the classical GPR technique, the RGPR model can handle domains with a large number of activities that require very large training sets. The developed RGPR-based GLRT method aims first to build a RGPR model, then, it consists to apply GLRT to the monitored residuals obtained from PGPR for fault detection purposes. The fault detection performance of the developed RGPR-based GLRT method is illustrated through the Tennessee Eastman process. The simulation results show that the RGPR-based GLRT method outperforms the conventional GPR-based GLRT technique in terms of miss detection rate and CPU-time.

关键词： Gaussian process regression (GPR) reduced Gaussian process regression (RGPR) Kmeans fault detection generalized likelihood ratio test (GLRT) chemical processes

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Metrics Reloaded: Recommendations for image analysis validation

arXiv

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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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Benchmarking quality-dependent and cost-sensitive score-level multimodal biometric fusion algorithms

arXiv

引用

arXiv 2021年

作者： Poh, Norman Bourlai, Thirimachos Kittler, Josef Allano, Lorene Alonso-Fernandez, Fernando Ambekar, Onkar Baker, John Dorizzi, Bernadette Fatukasi, Omolara Fierrez, Julian Ganster, Harald Ortega-Garcia, Javier Maurer, Donald Salah, Albert Ali Scheidat, Tobias Vielhauer, Claus Centre for Vision Speech and Signal Processing School of Electronics and Physical Sciences University of Surrey Guildford SurreyGU2 7XH United Kingdom Biometrics Center Lane Department of Computer Science and Electrical Engineering College of Engineering and Mineral Resources West Virginia University MorgantownWV26506-6109 United States Institut Telecom Telecom and Management SudParis Evry91011 France Biometric Recognition Group – ATVS Escuela Politecnica Superior Universidad Autonoma de Madrid Madrid28049 Spain Amsterdam1098 XG Netherlands Applied Physics Laboratory Johns Hopkins University LaurelMD20723 United States Electronics and Physics Department Institut Telecom Telecom and Management SudParis Evry91011 France Institute of Digital Image Processing Joanneum Research Graz8010 Austria ISLA-ISIS University of Amsterdam Amsterdam1098 XG Netherlands Department of Informatics and Media Brandenburg University of Applied Sciences Brandenburg an der HavelD-14770 Germany Research Group Multimedia and Security Department of Technical and Business Information Systems Faculty of Computer Science Otto-von-Guericke-University of Magdeburg MagdeburgD-39106 Germany

Automatically verifying the identity of a person by means of biometrics (e.g., face and fingerprint) is an important application in our day-to-day activities such as accessing banking services and security control in airports. To increase the system reliability, several biometric devices are often used. Such a combined system is known as a multimodal biometric system. This paper reports a benchmarking study carried out within the framework of the BioSecure DS2 (Access Control) evaluation campaign organized by the University of Surrey, involving face, fingerprint, and iris biometrics for person authentication, targeting the application of physical access control in a medium-size establishment with some 500 persons. While multimodal biometrics is a well-investigated subject in the literature, there exists no benchmark for a fusion algorithm comparison. Working towards this goal, we designed two sets of experiments: quality-dependent and cost-sensitive evaluation. The quality-dependent evaluation aims at assessing how well fusion algorithms can perform under changing quality of raw biometric images principally due to change of devices. The cost-sensitive evaluation, on the other hand, investigates how well a fusion algorithm can perform given restricted computation and in the presence of software and hardware failures, resulting in errors such as failure-to-acquire and failure-to-match. Since multiple capturing devices are available, a fusion algorithm should be able to handle this nonideal but nevertheless realistic scenario. In both evaluations, each fusion algorithm is provided with scores from each biometric comparison subsystem as well as the quality measures of both the template and the query data. The response to the call of the evaluation campaign proved very encouraging, with the submission of 22 fusion systems. To the best of our knowledge, this campaign is the first attempt to benchmark quality-based multimodal fusion algorithms. In the presence of changing

关键词： Benchmarking

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OCTAVA: An open-source toolbox for quantitative analysis of optical coherence tomography angiography images

arXiv

引用

arXiv 2021年

作者： Untracht, Gavrielle R. Matos, Rolando Dikaios, Nikolaos Bapir, Mariam Durrani, Abdullah K. Butsabong, Teemapron Campagnolo, Paola Sampson, David D. Heiss, Christian Sampson, Danuta M. Optical+Biomedical Engineering Laboratory School of Electrical Electronic and Computer Engineering The University of Western Australia 35 Stirling Highway PerthWA6009 Australia Surrey Biophotonics Advanced Technology Institute School of Physics School of Biosciences and Medicine University of Surrey Surrey GuildfordGU2 7XH United Kingdom Department of Biochemical Sciences Department of Clinical and Experimental Medicine School of Biosciences and Medicine University of Surrey Surrey GuildfordGU2 7XH United Kingdom Mathematics Research Center Academy of Athens Athens106 79 Greece Surrey and Sussex Healthcare NHS Trust East Surrey Hospital Surrey RedhillRH1 5RH United Kingdom Surrey Biophotonics Centre for Vision Speech and Signal Processing School of Biosciences and Medicine The University of Surrey GuildfordGU2 7XH United Kingdom

Optical coherence tomography angiography (OCTA) performs non-invasive visualization and characterization of microvasculature in research and clinical applications mainly in ophthalmology and dermatology. A wide variety of instruments, imaging protocols, processing methods and metrics have been used to describe the microvasculature, such that comparing different study outcomes is currently not feasible. With the goal of contributing to standardization of OCTA data analysis, we report a user-friendly, open-source toolbox, OCTAVA (OCTA Vascular Analyzer), to automate the pre-processing, segmentation, and quantitative analysis of en face OCTA maximum intensity projection images in a standardized workflow. We present each analysis step, including optimization of filtering and choice of segmentation algorithm, and definition of metrics. We perform quantitative analysis of OCTA images from different commercial and non-commercial instruments and samples and show OCTAVA can accurately and reproducibly determine metrics for characterization of microvasculature. Wide adoption could enable studies and aggregation of data on a scale sufficient to develop reliable microvascular biomarkers for early detection, and to guide treatment, of microvascular disease. © 2021, CC BY-NC-SA.

关键词： Optical tomography

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FAST NON-LINEAR METHODS FOR DYNAMIC TEXTURE PREDICTION

FAST NON-LINEAR METHODS FOR DYNAMIC TEXTURE PREDICTION

引用

IEEE International Conference on image processing

作者： Sameeksha Katoch Pavan Turaga Andreas Spanias Cihan Tepedelenlioglu School of Electrical Computer Energy Engineering Sensor Signal and Information Processing (SenSIP) Center

This paper aims to develop a fast dynamic-texture prediction method, using tools from non-linear dynamical modeling, and fast approaches for approximate regression. We consider dynamic textures to be described by patch-level non-linear processes, thus requiring tools such as delay-embedding to uncover a phase-space where dynamical evolution can be more easily modeled. After mapping the observed time-series from a dynamic texture video to its recovered phase-space, a time-efficient approximate prediction method is presented which utilizes locality-sensitive hashing approaches to predict possible phase-space vectors, given the current phase- space vector. Our experiments show the favorable performance of the proposed approach, both in terms of prediction fidelity, and computational time. The proposed algorithm is applied to shading prediction in utility scale solar arrays.

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Analysis and experimental demonstration of orthant-symmetric four-dimensional 7 bit/4D-sym modulation for optical fiber communication

arXiv

引用

arXiv 2020年

作者： Chen, Bin Alvarado, Alex van der Heide, Sjoerd van den Hout, Menno Hafermann, Hartmut Okonkwo, Chigo The School of Computer Science and Information Engineering Hefei University of Technology Hefei China Eindhoven University of Technology Eindhoven5600 MB Netherlands The Information and Communication Theory Lab Signal Processing Systems Group Department of Electrical Engineering Eindhoven University of Technology Eindhoven5600 MB Netherlands The High Capacity Optical Transmission Laboratory Eindhoven University of Technology Eindhoven5600 MB Netherlands The Optical Communication Technology Lab Paris Research Center Huawei Technologies France SASU Boulogne-Billancourt92100 France

We propose a new four-dimensional orthant-symmetric 128-ary modulation format (4D-OS128) with a spectral efficiency of 7 bit/4D-sym. The proposed format fills the gap between polarization-multiplexed 8- and 16-ary quadrature-amplitude modulation (PM-8QAM and PM-16QAM). Numerical simulations show that 4D-OS128 outperforms two well-studied 4D geometrically-shaped modulation formats: 128SP-16QAM and 7b4D-2A8PSK by up to 0.65 dB for bit-interleaved coded modulation at the same spectral efficiency. These gains are experimentally demonstrated in a 11×233 Gbit/s wavelength division multiplexing (WDM) transmission system operating at 5.95 bit/4D-sym over 6000 km and 9000 km for both EDFA-only and hybrid amplification scenarios, respectively. A reach increase of 15% is achieved with respect to 128-ary set-partitioning 16QAM. Furthermore, the proposed 4D-OS128 is also compared to D4 lattice-based constellation, 16QAM and probabilistically-shaped 16QAM with finite blocklength via simulation. © 2020, CC BY.

关键词： Quadrature amplitude modulation

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Publisher Correction: Brain imaging with portable low-field MRI

Nature Reviews Bioengineering

引用

Nature Reviews Bioengineering 2023年 680页

作者： W. Taylor Kimberly Annabel J. Sorby-Adams Andrew G. Webb Ed X. Wu Rachel Beekman Kevin N. Sheth Ritvij Bowry Steven J. Schiff Adam de Havenon Francis X. Shen Gordon Sze Pamela Schaefer Juan Eugenio Iglesias Matthew S. Rosen Department of Neurology and the Center for Genomic Medicine Massachusetts General Hospital and Harvard Medical School Boston MA USA Department of Radiology Leiden University Medical Center Leiden The Netherlands Laboratory of Biomedical Imaging and Signal Processing Department of Electrical and Electronic Engineering The University of Hong Kong Hong Kong SAR China Division of Neurocritical Care and Emergency Neurology Department of Neurology Yale New Haven Hospital and Yale School of Medicine Yale Center for Brain & Mind Health New Haven CT USA Departments of Neurosurgery and Neurology McGovern Medical School University of Texas Health Neurosciences Houston TX USA Department of Neurosurgery Yale School of Medicine New Haven CT USA Division of Vascular Neurology Department of Neurology Yale New Haven Hospital and Yale School of Medicine New Haven CT USA Harvard Medical School Center for Bioethics Harvard law School Boston MA USA Department of Psychiatry Massachusetts General Hospital Boston MA USA Department of Radiology Yale New Haven Hospital and Yale School of Medicine New Haven CT USA Division of Neuroradiology Department of Radiology Massachusetts General Hospital and Harvard Medical School Boston MA USA Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology Massachusetts General Hospital and Harvard Medical School Boston MA USA Centre for Medical Image Computing University College London London UK Computer Science and AI Laboratory Massachusetts Institute of Technology Boston MA USA

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