Designer chromosomes are artificially synthesized ***,these chromosomes have numerous applications ranging from medical research to the development of ***,some chromosome fragments can interfere with the chemical synt...
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Designer chromosomes are artificially synthesized ***,these chromosomes have numerous applications ranging from medical research to the development of ***,some chromosome fragments can interfere with the chemical synthesis of designer chromosomes and eventually limit the widespread use of this *** address this issue,this study aimed to develop an interpretable machine learning framework to predict and quantify the synthesis difficulties of designer chromosomes in *** the use of this framework,six key sequence features leading to synthesis difficulties were identified,and an e Xtreme Gradient Boosting model was established to integrate these *** predictive model achieved high-quality performance with an AUC of 0.895 in cross-validation and an AUC of 0.885 on an independent test *** on these results,the synthesis difficulty index(S-index)was proposed as a means of scoring and interpreting synthesis difficulties of chromosomes from prokaryotes to *** findings of this study emphasize the significant variability in synthesis difficulties between chromosomes and demonstrate the potential of the proposed model to predict and mitigate these difficulties through the optimization of the synthesis process and genome rewriting.
The proliferation of behind-the-meter (BTM) distributed energy resources (DER) within the electrical distribution network presents significant supply and demand flexibilities, but also introduces operational challenge...
Privacy violations are common in our technology-driven world, where almost everyone interacts with internet-connected electronic devices. To address this, cryptography has emerged, concealing data during transmission ...
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Morse code is one of the oldest communication techniques and used in telecommunication systems. Morse code can be transmitted as a visual signal by using reflections or with the help of flashlights, but it can also be...
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System health monitoring is an essential task in the operation and maintenance of any photovoltaic (PV) system. Typically, electroluminescence (EL), thermal imaging, and current-voltage (IV) curve analyses are used to...
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IoT has been introduced to improve production efficiency in small and medium-sized manufacturing companies, and it is mainly aimed at measuring machinery statuses. The improvement of changeover time is significant for...
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Metallised polypropylene film capacitors(MPPFCs)are widely used in power electronics and are generally degraded by elevated *** work aims to determine the relationships between the structural changes of MPPFC and the ...
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Metallised polypropylene film capacitors(MPPFCs)are widely used in power electronics and are generally degraded by elevated *** work aims to determine the relationships between the structural changes of MPPFC and the microstructural variations of the PP film during the thermal ageing of MPPFC at 100℃ for 38 *** capacitance of MPPFC has a slight decrease during thermal ***,the breakdown voltage of the MPPFC decreases by 39.4%by the *** partial discharge(PD)number of MPPFC increases linearly with ageing *** tear-down analysis of the MPPFC reveals that the molecular structure of the PP film has not been altered but has led to molecular chain scission and the generation of some polar fragments/***,the relative permittivity of the PP films rises as the ageing time ***,thermal ageing causes the conversion of aluminum to alumina in the metallised electrode,which is hydrophilic for polar groups and leads to an adhesion effect between the metallised electrodes and the PP *** angle measurements prove that the surface hydrophilicity of the PP sample increased after thermal ***,the PD/breakdown voltage in the MPPFC increases/decreases due to the uneven adhesion of the metallised PP film.
Intent-driven orchestration enables organizations to achieve greater automation, integration, and intelligence of their compute and network resources by defining their objectives and policies in a more abstract and ho...
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Most existing domain adaptation(DA) methods aim to explore favorable performance under complicated environments by ***,there are three unsolved problems that limit their efficiencies:ⅰ) they adopt global sampling but...
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Most existing domain adaptation(DA) methods aim to explore favorable performance under complicated environments by ***,there are three unsolved problems that limit their efficiencies:ⅰ) they adopt global sampling but neglect to exploit global and local sampling simultaneously;ⅱ)they either transfer knowledge from a global perspective or a local perspective,while overlooking transmission of confident knowledge from both perspectives;and ⅲ) they apply repeated sampling during iteration,which takes a lot of *** address these problems,knowledge transfer learning via dual density sampling(KTL-DDS) is proposed in this study,which consists of three parts:ⅰ) Dual density sampling(DDS) that jointly leverages two sampling methods associated with different views,i.e.,global density sampling that extracts representative samples with the most common features and local density sampling that selects representative samples with critical boundary information;ⅱ)Consistent maximum mean discrepancy(CMMD) that reduces intra-and cross-domain risks and guarantees high consistency of knowledge by shortening the distances of every two subsets among the four subsets collected by DDS;and ⅲ) Knowledge dissemination(KD) that transmits confident and consistent knowledge from the representative target samples with global and local properties to the whole target domain by preserving the neighboring relationships of the target *** analyses show that DDS avoids repeated sampling during the *** the above three actions,confident knowledge with both global and local properties is transferred,and the memory and running time are greatly *** addition,a general framework named dual density sampling approximation(DDSA) is extended,which can be easily applied to other DA *** experiments on five datasets in clean,label corruption(LC),feature missing(FM),and LC&FM environments demonstrate the encouraging performance of KTL-DDS.
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