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3rd Annual Conference of the Healthgrid Association, Healthgrid 2005

作者： Breton, Vincent Dean, Kevin Solomonides, Tony Aloisio, Giovanni Benkner, Siegfried Bilofsky, Howard Blanquer, Ignacio Brady, Michael Cannataro, Mario Chouvarda, Ioanna Claerhout, Brecht De Moor, Georges De Neve, Wilfried De Wagter, Carlos Fiore, Sandro Hassan, Kinda Heeren, Germaine Hernández, Vicente Herveg, Jean A.M. Hofmann, Martin Jones, Chris Koutkias, Vassilios Lloyd, Sharon Lonsdale, Guy Alonso, Victoria L. Maglaveras, Nicos Maigne, Lydia Malousi, Andigoni Martín-Sánchez, Fernando McClatchey, Richard Medico, Enzo Miguet, Serge Mirto, Maria Montagnat, Johan Nørager1, Sofie Nozaki, Kazunori Oliveira, Ilídio Castro Pennec, Xavier Poullet, Yves Merino, Juan Pedro Sánchez Strizh, Irina G. Taillet, Michel Tristram, Clive Tverdokhlebov, Nikolay Veltri, Pierangelo Ziegler, René CNRS-IN2P3 LPC Campus des Cézeaux AubiereCedex63177 France Internet Business Solutions Group Cisco Systems 9 New Square Bedfont Lakes Middlesex FelthamTW14 8HA United Kingdom University of the West of England Bristol CEMS Coldharbour Lane BristolBS6 6TH United Kingdom Center for Advanced Computational Technologies ISUFI Dept. of Innovation Engineering University of Lecce Via per Monteroni Lecce73100 Italy Institute of Scientific Computing University of Vienna Nordbergstrasse 15 ViennaA-1090 Austria University of Pennsylvania School of Engineering and Applied Science Computer and Information Science Center for Bioinformatics 1416 Blockley Hall 423 Guardian Drive PhiladelphiaPA19104-6021 United States Universidad Politecnica de Valencia Camino de Vera/n Valencia46022 Spain FRS FREng Dept. of Engineering Science Oxford University Parks Road OxfordOX1 3PJ United Kingdom Magna Graecia University of Catanzaro School of Bioinformatics and Biomedical Engineering Campus di Germaneto Viale Europa Germaneto Catanzaro88100 Italy Aristotle University The Medical School Lab of Medical Informatics Box 323 Thessaloniki54124 Greece Custodix NV Verlorenbroodstraat 120 Bus 14 MerelbekeB-9820 Belgium Research in Advanced Medical Informatics and Telematics UZ Gent 5K3 De Pintelaan 185 GentB9000 Belgium Department of Radiotherapy Ghent University Hospital Building P7 De Pintelaan 185 GentB-9000 Belgium Laboratoire LIRIS Université Lumière Lyon 2 Campus Porte des Alpes 5 avenue Pierre Mendès France Bron69676 France av. E.Mounierlaan 83 Brussels1200 Belgium Faculté de Droit de Namur - FUNDP Centre de Recherches Informatiques & Droit 5 rempart de la Vierge Namur5000 Belgium Schloss Birlinghoven Sankt Augustin53754 Germany CERN Geneva 231211 Switzerland Oxford University Computing Laboratory Wolfson Building OxfordOX1 3QD United Kingdom C&C Research Laboratories NEC Europe Ltd. Rathausallee 10 Sankt AugustinD-53757 Germany Medic

ISBN: (纸本)158603510X

Over the last four years, a community of researchers working on Grid and High Performance computing technologies started discussing the barriers and opportunities that grid technologies must face and exploit for the development of health-related applications. This interest lead to the first Healthgrid conference, held in Lyon, France, on January 16th–17th, 2003, with the focus of creating increased awareness about the possibilities and advantages linked to the deployment of grid technologies in health, ultimately targeting the creation of a European/international grid infrastructure for health. The topics of this conference converged with the position of the eHealth division of the European Commission, whose mandate from the Lisbon Meeting was "To develop an intelligent environment that enables ubiquitous management of citizens’ health status, and to assist health professionals in coping with some major challenges, risk management and the integration into clinical practice of advances in health knowledge." In this context "Health" involves not only clinical procedures but covers the whole range of information from molecular level (genetic and proteomic information) over cells and tissues, to the individual and finally the population level (social healthcare). Grid technology offers the opportunity to create a common working backbone for all different members of this large "health family" and will hopefully lead to an increased awareness and interoperability among disciplines. The first HealthGrid conference led to the creation of the Healthgrid association, a non-profit research association legally incorporated in France but formed from the broad community of European researchers and institutions sharing expertise in health grids. After the second Healthgrid conference, held in Clermont-Ferrand on January 29th–30th, 2004, the need for a "white paper" on the current status and prospective of health grids was raised. Over fifty experts from different areas of grid tec

关键词： Health risks

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Molybdenum Disulfide: Scalable Fabrication of Molybdenum Disulfide Nanostructures and their Assembly (Adv. Mater. 43/2020)

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Advanced Materials 2020年第43期32卷

作者： Yun Huang Kang Yu Huaizhi Li Kai Xu Zexi Liang Debora Walker Paulo Ferreira Peer Fischer Donglei (Emma) Fan Materials Science and Engineering Program Texas Materials Institute The University of Texas at Austin Austin TX 78712 USA The Department of Advanced Electron Microscopy Imaging and Spectroscopy International Iberian Nanotechnology Laboratory Braga 4715‐330 Portugal Electrical and Computer Engineering University of Illinois at Urbana‐Champaign Urbana IL 61801 USA School of Engineering and Applied Sciences Harvard University Cambridge MA 02138 USA Mechanical Engineering Department and IDMEC Instituto Superior Técnico University of Lisbon Av. Rovisco Pais Lisboa 1049‐001 Portugal Max‐Planck‐Institute for Intelligent Systems Heisenbergstr. 3 Stuttgart 70569 Germany Institute of Physical Chemistry University of Stuttgart Pfaffenwaldring 55 Stuttgart 70569 Germany Walker Department of Mechanical Engineering The University of Texas at Austin Austin TX 78712 USA

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Conformational Dynamics of apo‐GlnBP Revealed by Experimental and Computational Analysis

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Angewandte Chemie 2016年第45期128卷

作者： Yitao Feng Lu Zhang Shaowen Wu Zhijun Liu Xin Gao Xu Zhang Maili Liu Jianwei Liu Xuhui Huang Wenning Wang Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of Chemistry and Institutes of Biomedical Sciences Fudan University Shanghai P.R. China Department of Chemistry The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong National Center for Protein Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai China King Abdullah University of Science and Technology (KAUST) Computational Bioscience Research Center (CBRC) Computer Electrical and Mathematical Sciences and Engineering (CEMSE) Division Thuwal 23955 Saudi Arabia Key Laboratory of Magnetic and Resonance in Biological Systems State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Centre for Magnetic Resonance Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences Wuhan China Division of Biomedical Engineering Center of Systems Biology and Human Health Institute for Advance Study and School of Science The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong

The glutamine binding protein (GlnBP) binds l ‐glutamine and cooperates with its cognate transporters during glutamine uptake. Crystal structure analysis has revealed an open and a closed conformation for apo‐ and holo‐GlnBP, respectively. However, the detailed conformational dynamics have remained unclear. Herein, we combined NMR spectroscopy, MD simulations, and single‐molecule FRET techniques to decipher the conformational dynamics of apo‐GlnBP. The NMR residual dipolar couplings of apo‐GlnBP were in good agreement with a MD‐derived structure ensemble consisting of four metastable states. The open and closed conformations are the two major states. This four‐state model was further validated by smFRET experiments and suggests the conformational selection mechanism in ligand recognition of GlnBP.

关键词： FRET Konformationsdynamik Moleküldynamik NMR-Spektroskopie Proteinfaltung

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The state-of-the-art in Cardiac MRI Reconstruction: Results of the CMRxRecon Challenge in MICCAI 2023

arXiv

引用

arXiv 2024年

作者： Lyu, Jun Qin, Chen Wang, Shuo Wang, Fanwen Li, Yan Wang, Zi Guo, Kunyuan Ouyang, Cheng Tänzer, Michael Liu, Meng Sun, Longyu Sun, Mengting Li, Qin Shi, Zhang Hua, Sha Li, Hao Chen, Zhensen Zhang, Zhenlin Xin, Bingyu Metaxas, Dimitris N. Yiasemis, George Teuwen, Jonas Zhang, Liping Chen, Weitian Pang, Yanwei Liu, Xiaohan Razumov, Artem Dylov, Dmitry V. Dou, Quan Yan, Kang Xue, Yuyang Du, Yuning Dietlmeier, Julia Garcia-Cabrera, Carles Hemidi, Ziad Al-Haj Vogt, Nora Xu, Ziqiang Zhang, Yajing Chu, Ying-Hua Chen, Weibo Bai, Wenjia Zhuang, Xiahai Qin, Jing Wu, Lianmin Yang, Guang Qu, Xiaobo Wang, He Wang, Chengyan Psychiatry Neuroimaging Laboratory Brigham and Women’s Hospital Harvard Medical School 399 Revolution Drive BostonMA02215 United States Department of Electrical and Electronic Engineering & I-X Imperial College London United Kingdom Digital Medical Research Center School of Basic Medical Sciences Fudan University Shanghai China Department of Bioengineering & I-X Imperial College London LondonW12 7SL United Kingdom Cardiovascular Magnetic Resonance Unit Royal Brompton Hospital Guy’s and St Thomas’ NHS Foundation Trust LondonSW3 6NP United Kingdom Department of Radiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of Electronic Science Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance National Institute for Data Science in Health and Medicine Institute of Artificial Intelligence Xiamen University Xiamen361102 China Department of Computing Department of Brain Sciences Imperial College London LondonSW7 2AZ United Kingdom Human Phenome Institute Fudan University 825 Zhangheng Road Pudong New District Shanghai201203 China Department of Radiology Zhongshan Hospital Fudan University Shanghai China Department of Cardiovascular Medicine Ruijin Hospital Lu Wan Branch Shanghai Jiao Tong University School of Medicine Shanghai China Institute of Science and Technology for Brain-Inspired Intelligence Fudan University Shanghai200433 China Department of Computer Science Rutgers University PiscatawayNJ08854 United States AI for Oncology Netherlands Cancer Institute Plesmanlaan 121 Amsterdam1066 CX Netherlands Department of Imaging and Interventional Radiology The Chinese University of Hong Kong Hong Kong TJK-BIIT Lab School of Electrical and Information Engineering Tianjin University Tianjin300072 China Skolkovo Institute Of Science And Technology Center for Artificial Intelligence Technology 30/1 Bolshoy blvd. Moscow121205 Russia Department of Biomedical Engineering University of Virginia

Cardiac magnetic resonance imaging (MRI) provides detailed and quantitative evaluation of the heart’s structure, function, and tissue characteristics with high-resolution spatial-temporal imaging. However, its slow imaging speed and motion artifacts are notable limitations. Undersampling reconstruction, especially data-driven algorithms, has emerged as a promising solution to accelerate scans and enhance imaging performance using highly under-sampled data. Nevertheless, the scarcity of publicly available cardiac k-space datasets and evaluation platform hinder the development of data-driven reconstruction algorithms. To address this issue, we organized the Cardiac MRI Reconstruction Challenge (CMRxRecon) in 2023, in collaboration with the 26th International Conference on Medical Image computing and computer-Assisted Intervention (MICCAI). CMRxRecon presented an extensive k-space dataset comprising cine and mapping raw data, accompanied by detailed annotations of cardiac anatomical structures. With overwhelming participation, the challenge attracted more than 285 teams and over 600 participants. Among them, 22 teams successfully submitted Docker containers for the testing phase, with 7 teams submitted for both cine and mapping tasks. All teams use deep learning based approaches, indicating that deep learning has predominately become a promising solution for the problem. The first-place winner of both tasks utilizes the E2E-VarNet architecture as backbones. In contrast, U-Net is still the most popular backbone for both multi-coil and single-coil reconstructions. This paper provides a comprehensive overview of the challenge design, presents a summary of the submitted results, reviews the employed methods, and offers an in-depth discussion that aims to inspire future advancements in cardiac MRI reconstruction models. The summary emphasizes the effective strategies observed in Cardiac MRI reconstruction, including backbone architecture, loss function, pre-processing techn

关键词： Mapping

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Author Correction: Frontotemporal coordination predicts working memory performance and its local neural signatures

引用

Nature communications 2021年第1期12卷 3811页

作者： Ehsan Rezayat Mohammad-Reza A Dehaqani Kelsey Clark Zahra Bahmani Tirin Moore Behrad Noudoost School of Cognitive Sciences Institute for Research in Fundamental Sciences (IPM) Tehran Iran. School of Cognitive Sciences Institute for Research in Fundamental Sciences (IPM) Tehran Iran. dehaqani@ut.ac.ir. Cognitive Systems Laboratory Control and Intelligent Processing Center of Excellence (CIPCE) School of Electrical and Computer Engineering College of Engineering University of Tehran Tehran Iran. dehaqani@ut.ac.ir. Department of Ophthalmology and Visual Sciences University of Utah Salt Lake City UT USA. Department of Biomedical Engineering Tarbiat Modares University Tehran Iran. Department of Neurobiology Stanford University Stanford CA USA. Howard Hughes Medical Institute Stanford University Stanford CA USA. Department of Ophthalmology and Visual Sciences University of Utah Salt Lake City UT USA. behrad.noudoost@utah.edu.

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Eye tracking: empirical foundations for a minimal reporting guideline

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Behavior research methods 2023年第1期55卷 364-416页

作者： Kenneth Holmqvist Saga Lee Örbom Ignace T C Hooge Diederick C Niehorster Robert G Alexander Richard Andersson Jeroen S Benjamins Pieter Blignaut Anne-Marie Brouwer Lewis L Chuang Kirsten A Dalrymple Denis Drieghe Matt J Dunn Ulrich Ettinger Susann Fiedler Tom Foulsham Jos N van der Geest Dan Witzner Hansen Samuel B Hutton Enkelejda Kasneci Alan Kingstone Paul C Knox Ellen M Kok Helena Lee Joy Yeonjoo Lee Jukka M Leppänen Stephen Macknik Päivi Majaranta Susana Martinez-Conde Antje Nuthmann Marcus Nyström Jacob L Orquin Jorge Otero-Millan Soon Young Park Stanislav Popelka Frank Proudlock Frank Renkewitz Austin Roorda Michael Schulte-Mecklenbeck Bonita Sharif Frederick Shic Mark Shovman Mervyn G Thomas Ward Venrooij Raimondas Zemblys Roy S Hessels Department of Psychology Nicolaus Copernicus University Torun Poland. kenneth.holmqvist@ur.de. Department of Computer Science and Informatics University of the Free State Bloemfontein South Africa. kenneth.holmqvist@ur.de. Department of Psychology Regensburg University Regensburg Germany. kenneth.holmqvist@ur.de. Department of Psychology Regensburg University Regensburg Germany. Experimental Psychology Helmholtz Institute Utrecht University Utrecht The Netherlands. Lund University Humanities Lab and Department of Psychology Lund University Lund Sweden. Department of Ophthalmology SUNY Downstate Health Sciences University Brooklyn NY USA. Tobii Pro AB Danderyd Sweden. Social Health and Organizational Psychology Utrecht University Utrecht The Netherlands. Department of Computer Science and Informatics University of the Free State Bloemfontein South Africa. TNO Soesterberg The Netherlands. Department of Ergonomics Leibniz Institute for Working Environments and Human Factors Dortmund Germany. Institute of Informatics LMU Munich Munich Germany. Institute of Child Development University of Minnesota Minneapolis USA. School of Psychology University of Southampton Southampton UK. School of Optometry and Vision Sciences Cardiff University Cardiff UK. Department of Psychology University of Bonn Bonn Germany. Vienna University of Economics and Business Vienna Austria. Department of Psychology University of Essex Essex UK. Department of Neuroscience Erasmus MC Rotterdam The Netherlands. Machine Learning Group Department of Computer Science IT University of Copenhagen Copenhagen Denmark. SR Research Ltd Ottawa Canada. Human-Computer Interaction University of Tübingen Tübingen Germany. University of British Columbia Columbia Canada. Department of Eye and Vision Science Institute of Life Course and Medical Sciences University of Liverpool Liverpool UK. Department of Education and Pedagogy Division Education Faculty of Social and Behavioral Sciences Ut

In this paper, we present a review of how the various aspects of any study using an eye tracker (such as the instrument, methodology, environment, participant, etc.) affect the quality of the recorded eye-tracking data and the obtained eye-movement and gaze measures. We take this review to represent the empirical foundation for reporting guidelines of any study involving an eye tracker. We compare this empirical foundation to five existing reporting guidelines and to a database of 207 published eye-tracking studies. We find that reporting guidelines vary substantially and do not match with actual reporting practices. We end by deriving a minimal, flexible reporting guideline based on empirical research (Section "An empirically based minimal reporting guideline").

关键词： Data quality Eye movements Eye tracking Replicability Reporting guidelines Reporting practices Reporting standards Reproducibility

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Unlocking capacities of viral genomics for the COVID-19 pandemic response

arXiv

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arXiv 2021年

作者： Knyazev, Sergey Chhugani, Karishma Sarwal, Varuni Ayyala, Ram Singh, Harman Karthikeyan, Smruthi Deshpande, Dhrithi Comarova, Zoia Lu, Angela Porozov, Yuri Wu, Aiping Abedalthagafi, Malak S. Nagaraj, Shivashankar H. Smith, Adam L. Skums, Pavel Ladner, Jason Lam, Tommy Tsan-Yuk Wu, Nicholas C. Zelikovsky, Alex Knight, Rob Crandall, Keith A. Mangul, Serghei Department of Computer Science College of Art and Science Georgia State University 1 Park Place AtlantaGA30303 United States Department of Pharmacology and Pharmaceutical Sciences School of Pharmacy University of Southern California 1985 Zonal Avenue Los AngelesCA90089 United States Department of Computer Science University of California Los Angeles 580 Portola Plaza Los AngelesCA90095 United States Department of Neuroscience College of Life Sciences University of California Los Angeles 580 Portola Plaza Los AngelesCA90095 United States Department of Electrical Engineering Indian Institute of Technology Hauz Khas New Delhi110016 India Department of Pediatrics University of California San Diego San DiegoCA United States Paradigm Environmental 3911 Old Lee Highway FairfaxVA22030 United States Department of Pharmacology and Pharmaceutical Sciences School of Pharmacy University of Southern California 1985 Zonal Avenue Los AngelesCA90089-9121 United States World-Class Research Center Digital Biodesign and Personalized Healthcare I.M. Sechenov First Moscow State Medical University Moscow Russia Department of Computational Biology Sirius University of Science and Technology Sochi Russia Center for Systems Medicine Institute of Basic Medical Sciences Chinese Academy of Medical Sciences Peking Union Medical College Beijing100005 China Suzhou Institute of Systems Medicine Suzhou215123 China Genomics Research Department Saudi Human Genome Project King Fahad Medical City King Abdulaziz City for Science and Technology Riyadh Saudi Arabia Centre for Genomics and Personalised Health Queensland University of Technology BrisbaneQLD4059 Australia Translational Research Institute Brisbane Australia Astani Department of Civil and Environmental Engineering University of Southern California 3620 South Vermont Avenue Los AngelesCA90089 United States Department of Computer Science College of Art and Science Georgia State University 1 Park Place Atlanta

More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies, the rapid global spread of SARS-CoV-2, and its persistent threat to public health. However, distinguishing the most epidemiologically relevant information encoded in these vast amounts of data requires substantial effort across the research and public health communities. Studies of SARS-CoV-2 genomes have been critical in tracking the spread of variants and understanding its epidemic dynamics, and may prove crucial for controlling future epidemics and alleviating significant public health burdens. Together, genomic data and bioinformatics methods enable broad-scale investigations of the spread of SARS-CoV-2 at the local, national, and global scales and allow researchers the ability to efficiently track the emergence of novel variants, reconstruct epidemic dynamics, and provide important insights into drug and vaccine development and disease control. Here, we discuss the tremendous opportunities that genomics offers to unlock the effective use of SARS-CoV-2 genomic data for efficient public health surveillance and guiding timely responses to COVID-19. © 2021, CC BY-NC-ND.

关键词： SARS

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Proceedings of the 16th Annual UT-KBRIN Bioinformatics Summit 2016: proceedings

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BMC Proceedings 2017年第9期11卷 1-6页

作者： L. Leon Dent Sammed N. Mandape Siddharth Pratap Jianan Dong Jamaine Davis Jennifer A. Gaddy Kofi Amoah Steve Damo Dana R. Marshall Jacob Jones Toni Brandt Gilberto Diaz Qingguo Wang Todd Gary Ashwini Yenamandra Marina Z. Ghattas Marwa Elrakaiby Ramy K. Aziz Hamdallah H. Zedan Moamen Elmassry Marwa ElRakaiby Mariam Lotfy Jarrad Marcel Rania A. Khattab Maha M. Abdelfattah Jack A. Gilbert Pouya Dini Shavahn C. Loux Kirsten E. Scoggin Alejandro Esteller-Vico Edward L. Squires Mats H. T. Troedsson Barry A. Ball Peter Daels Kalpani De Silva Ernest Bailey Joel C. Stephens Theodore S. Kalbfleisch Christine E. Dolin Lauren G. Poole Gavin E. Arteel Michael L. Merchant Daniel W. Wilkey Michelle T. Barati Eric C. Rouchka Richard M. Higashi Teresa W-M Fan Hunter Moseley Andrew N Lane Department of Surgery Meharry Medical College Nashville TN 37208 USA Bioinformatics Core Meharry Medical College Nashville TN 37208 USA Department of Biochemistry and Cancer Biology Meharry Medical College Nashville TN 37208 USA Department of Medicine Vanderbilt University Medical Center Nashville TN 37232 USA Department of Life and Physical Sciences Fisk University Nashville TN 37208 USA Department of Pathology Anatomy and Cell Biology Meharry Medical College Nashville TN 37208 USA College of Computing and Technology Lipscomb University 1 University Park Drive Nashville TN 37204 USA Vanderbilt University Medical Center Nashville TN 37232 USA Office of Research Middle Tennessee State University 1301 East Main St Murfreesboro TN 37132 USA Department of Microbiology and Immunology Faculty of Pharmacy Cairo University Cairo Egypt Department of Biological Sciences Texas Tech University Lubbock TX 79409 USA Clinical Operations Department Ray-Clinical Research Organization Giza Egypt Genomic and Systems Biology Bioscience Division Argonne National Laboratory Argonne IL 60439 USA Research Institute of Ophthalmology Giza Egypt Department of Surgery University of Chicago Chicago IL 60637 USA Microbial Ecology Group Argonne National Laboratory Argonne IL 60439 USA Department of Veterinary Science University of Kentucky Lexington KY 40536 USA Department of Reproduction Faculty of Veterinary Medicine University of Gent Merelbeke Belgium Interdisciplinary Studies Program: Specialization in Bioinformatics University of Louisville Louisville KY 40292 USA Department of Veterinary Science University of Kentucky Lexington KY 40506 USA Genomics GPS Guilford CT 06437 USA Department of Biochemistry and Molecular Genetics School of Medicine University of Louisville Louisville KY 40292 USA Department of Pharmacology & Toxicology University of Louisville Louisville KY 40202 USA Department of Medicine University of Louisville

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Precision orbital dynamics from interstellar scintillation arcs for PSR J0437−4715

arXiv

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arXiv 2020年

作者： Reardon, Daniel J. Coles, William A. Bailes, Matthew Bhat, N.D. Ramesh Dai, Shi Hobbs, George B. Kerr, Matthew Manchester, Richard N. Oslowski, Stefan Parthasarathy, Aditya Russell, Christopher J. Shannon, Ryan M. Spiewak, Renée Toomey, Lawrence Tuntsov, Artem V. van Straten, Willem Walker, Mark A. Wang, Jingbo Zhang, Lei Zhu, Xing-Jiang Centre for Astrophysics and Supercomputing Swinburne University of Technology P.O. Box 218 HawthornVIC3122 Australia Australia Electrical and Computer Engineering University of California at San Diego La Jolla CA United States International Centre for Radio Astronomy Research Curtin University BentleyWA6102 Australia Australia Telescope National Facility CSIRO Astronomy & Space Science P.O. Box 76 EppingNSW1710 Australia Space Science Division Naval Research Laboratory WashingtonDC20375-5352 United States CSIRO Scientific Computing Services Australian Technology Park Locked Bag 9013 AlexandriaNSW1435 Australia Manly Astrophysics 15/41-42 East Esplanade ManlyNSW2095 Australia Institute for Radio Astronomy & Space Research Auckland University of Technology Private Bag 92006 Auckland1142 New Zealand Xinjiang Astronomical Observatory Chinese Academy of Sciences 150 Science 1-Street Xinjiang Urumqi830011 China National Astronomical Observatories Chinese Academy of Sciences A20 Datun Road Chaoyang District Beijing100101 China University of Chinese Academy of Sciences Beijing100049 China School of Physics and Astronomy Monash University VIC3800 Australia

Intensity scintillations of radio pulsars are known to originate from interference between waves scattered by the electron density irregularities of interstellar plasma, often leading to parabolic arcs in the two-dimensional power spectrum of the recorded dynamic spectrum. The degree of arc curvature depends on the distance to the scattering plasma and its transverse velocity with respect to the line-of-sight. We report the observation of annual and orbital variations in the curvature of scintillation arcs over a period of 16 years for the bright millisecond pulsar, PSR J0437−4715. These variations are the signature of the relative transverse motions of the Earth, pulsar, and scattering medium, which we model to obtain precise measurements of parameters of the pulsar’s binary orbit and the scattering medium itself. We observe two clear scintillation arcs in most of our >5000 observations and we show that they originate from scattering by thin screens located at distances D1 = 89.8 ± 0.4 pc and D2 = 124 ± 3 pc from Earth. The best-fit scattering model we derive for the brightest arc yields the pulsar’s orbital inclination angle i = 137.1 ± 0.3◦, and longitude of ascending node, Ω = 206.3 ± 0.4◦. Using scintillation arcs for precise astrometry and orbital dynamics can be superior to modelling variations in the diffractive scintillation timescale, because the arc curvature is independent of variations in the level of turbulence of interstellar plasma. This technique can be used in combination with pulsar timing to determine the full three-dimensional orbital geometries of binary pulsars, and provides parameters essential for testing theories of gravity and constraining neutron star masses. Copyright © 2020, The Authors. All rights reserved.

关键词： Pulsars

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Searching for GEMS: Two Super-Jupiters around M-dwarfs – Signatures of Instability or Accretion?

arXiv

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arXiv 2024年

作者： Hotnisky, Andrew Kanodia, Shubham Libby-Roberts, Jessica Mahadevan, Suvrath Cañas, Caleb I. Gupta, Arvind F. Han, Te Kobulnicky, Henry A. Larsen, Alexander Robertson, Paul Rodruck, Michael Stefansson, Gudmundur Cochran, William D. Delamer, Megan Diddams, Scott A. Fernandes, Rachel B. Halverson, Samuel Hebb, Leslie Lin, Andrea S.J. Monson, Andrew Ninan, Joe P. Roy, Arpita Schwab, Christian Department of Astronomy & Astrophysics 525 Davey Laboratory The Pennsylvania State University University ParkPA16802 United States Center for Exoplanets and Habitable Worlds 525 Davey Laboratory The Pennsylvania State University University ParkPA16802 United States Earth and Planets Laboratory Carnegie Science 5241 Broad Branch Road NW WashingtonDC20015 United States Astrobiology Research Center 525 Davey Laboratory The Pennsylvania State University University ParkPA16802 United States NASA Goddard Space Flight Center 8800 Greenbelt Road GreenbeltMD20771 United States U.S. National Science Foundation National Optical-Infrared Astronomy Research Laboratory 950 N. Cherry Ave. TucsonAZ85719 United States Department of Physics & Astronomy The University of California Irvine IrvineCA92697 United States Department of Physics & Astronomy University of Wyoming LaramieWY82070 United States Department of Physics & Astronomy University of California Irvine IrvineCA92697 United States Department of Physics Engineering and Astrophysics Randolph-Macon College AshlandVA23005 United States Anton Pannekoek Institute for Astronomy University of Amsterdam Science Park 904 Amsterdam1098 XH Netherlands McDonald Observatory Department of Astronomy The University of Texas Austin United States Center for Planetary Systems Habitability The University of Texas Austin United States Electrical Computer & Energy Engineering University of Colorado 425 UCB BoulderCO80309 United States Department of Physics University of Colorado 2000 Colorado Avenue BoulderCO80309 United States Jet Propulsion Laboratory 4800 Oak Grove Drive PasadenaCA91109 United States Department of Physics Hobart and William Smith Colleges 300 Pulteney Street GenevaNY14456 United States Steward Observatory The University of Arizona 933 N. Cherry Avenue TucsonAZ85721 United States Department of Astronomy and Astrophysics Tata Institute of Fundamental Research Homi Bhabha Road

We present the discovery of TOI-6303b and TOI-6330b, two massive transiting super-Jupiters orbiting a M0 and a M2 star respectively, as part of the Searching for GEMS survey. These were detected by TESS and then confirmed via ground-based photometry and radial velocity observations with the Habitable-zone Planet Finder (HPF). TOI-6303b has a mass of 7.84 ± 0.31 MJ, a radius of 1.03 ± 0.06 RJ, and an orbital period of 9.485 days. TOI-6330b has a mass of 10.00 ± 0.31 MJ, a radius of 0.97 ± 0.03 RJ, and an orbital period of 6.850 days. We put these planets in context of super-Jupiters around M-dwarfs discovered from radial-velocity surveys, as well as recent discoveries from astrometry. These planets have masses that can be attributed to two dominant planet formation mechanisms — gravitational instability and core-accretion. Their masses necessitate massive protoplanetary disks that should either be gravitationally unstable, i.e. forming through gravitational instability, or be amongst some of the most massive protoplanetary disks to form objects through core-accretion. We also discuss the eccentricity distribution of these objects, as a potential indicator of their formation and evolutionary mechanisms. © 2024, CC BY.

关键词： Orbits

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