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arXiv 2022年

作者： Chen, Zhihao Chen, Yu Wu, Yaodong Zhou, Xinxing Sun, Handong Low, Tony Chen, Hongsheng Lin, Xiao Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control Ministry of Education Synergetic Innovation Center for Quantum Effects and Applications School of Physics and Electronics Hunan Normal University Changsha410081 China International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology Engineering Technology Research Center for 2D Material Information Function Devices and Systems of Guangdong Province Institute of Microscale Optoelectronics Shenzhen University Shenzhen518060 China Division of Physics and Applied Physics School of Physical and Mathematical Sciences Nanyang Technological University 637371 Singapore School of Physical and Mathematical Sciences Nanyang Technological University 637371 Singapore Department of Electrical and Computer Engineering University of Minnesota MinneapolisMN55455 United States Interdisciplinary Center for Quantum Information State Key Laboratory of Modern Optical Instrumentation ZJU-Hangzhou Global Scientific and Technological Innovation Center College of Information Science and Electronic Engineering Zhejiang University Hangzhou310027 China International Joint Innovation Center ZJU-UIUC Institute The Electromagnetics Academy at Zhejiang University Zhejiang University Haining314400 China

Photonic spin Hall effect is a manifestation of spin-orbit interaction of light and can be measured by a transverse shift δ of photons with opposite spins. The precise measurement of transverse shifts can enable many spin-related applications, such as precise metrology and optical sensing. However, this transverse shift is generally small (i.e. δ/λ -1, λ is the wavelength), which impedes its precise measurement. To-date proposals to generate giant spin Hall effect (namely with δ/λ > 102) have severe limitations, particularly its occurrence only over a narrow angular cone (with a width of ∆0 70◦ by exploiting the interface between free space and uniaxial epsilon-near-zero media. The underlying mechanism is ascribed to the almost-perfect polarization splitting between s and p polarized waves at the designed interface. Remarkably, this almost-perfect polarization splitting does not resort to the interference effect and is insensitive to the incident angle, which then gives rise to the wide-angle giant photonic spin Hall effect. Copyright © 2022, The Authors. All rights reserved.

关键词： Polarization

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Observation of quantum strong Mpemba effect

arXiv

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arXiv 2024年

作者： Zhang, Jie Xia, Gang Wu, Chun-Wang Chen, Ting Zhang, Qian Xie, Yi Su, Wen-Bo Wu, Wei Qiu, Cheng-Wei Chen, Ping-Xing Li, Weibin Jing, Hui Zhou, Yan-Li Institute for Quantum Science and Technology College of Science National University of Defense Technology Changsha410073 China Hunan Key Laboratory of Mechanism and technology of Quantum Information Changsha410073 China Hefei National Laboratory Anhui Hefei230088 China Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Hunan Normal University Changsha410081 China Department of Electrical and Computer Engineering National University of Singapore Singapore Singapore School of Physics and Astronomy University of Nottingham NottinghamNG7 2RD United Kingdom Centre for the Mathematics and Theoretical Physics of Quantum Non-equilibrium Systems University of Nottingham NottinghamNG7 2RD United Kingdom College of Science National University of Defense Technology Changsha410073 China

An ancient and counterintuitive phenomenon known as the Mpemba effect showcases the critical role of initial conditions in relaxation processes. How to realize and utilize this effect for speeding up relaxation is an important but challenging task in purely quantum system till now. Here, we experimentally study the strong Mpemba effect in a single trapped ion system in which an exponentially accelerated relaxation in time is observed by preparing an optimal quantum initial state with no excitation of the slowest decaying mode. Also, we demonstrate that the condition of realizing such effect coincides with the Liouvillian exceptional point, featuring the coalescence of both the eigenvalues and the eigenmodes of the systems. Our work provides an efficient strategy to engineer the dynamics of open quantum system, and suggests a link unexplored yet between the Mpemba effect and the non-Hermitian physics. Copyright © 2024, The Authors. All rights reserved.

关键词： Trapped ions

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A Radial Basis Function Spike Model for Indirect Learning via Integrate-and-Fire Sampling and Reconstruction Techniques

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Advances in Artificial Neural systems 2012年第1期2012卷

作者： X. Zhang G. Foderaro C. Henriquez A. M. J. VanDongen S. Ferrari Laboratory for Intelligent Systems and Control (LISC) Department of Mechanical Engineering and Materials Science Duke University Durham NC 27708 USAduke.edu Department of Biomedical Engineering and Department of Computer Science Duke University Durham NC 27708 USAduke.edu Program in Neuroscience & Behavioral Disorders Duke-NUS Graduate Medical School Singapore Singapore

This paper presents a deterministic and adaptive spike model derived from radial basis functions and a leaky integrate-and-fire sampler developed for training spiking neural networks without direct weight manipulation. Several algorithms have been proposed for training spiking neural networks through biologically-plausible learning mechanisms, such as spike-timing-dependent synaptic plasticity and Hebbian plasticity. These algorithms typically rely on the ability to update the synaptic strengths, or weights, directly, through a weight update rule in which the weight increment can be decided and implemented based on the training equations. However, in several potential applications of adaptive spiking neural networks, including neuroprosthetic devices and CMOS/memristor nanoscale neuromorphic chips, the weights cannot be manipulated directly and, instead, tend to change over time by virtue of the pre- and postsynaptic neural activity. This paper presents an indirect learning method that induces changes in the synaptic weights by modulating spike-timing-dependent plasticity by means of controlled input spike trains. In place of the weights, the algorithm manipulates the input spike trains used to stimulate the input neurons by determining a sequence of spike timings that minimize a desired objective function and, indirectly, induce the desired synaptic plasticity in the network.

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An Open-Source Knowledge Graph Ecosystem for the Life Sciences

arXiv

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arXiv 2023年

作者： Callahan, Tiffany J. Tripodi, Ignacio J. Stefanski, Adrianne L. Cappelletti, Luca Taneja, Sanya B. Wyrwa, Jordan M. Casiraghi, Elena Matentzoglu, Nicolas A. Reese, Justin Silverstein, Jonathan C. Hoyt, Charles Tapley Boyce, Richard D. Malec, Scott A. Unni, Deepak R. Joachimiak, Marcin P. Robinson, Peter N. Mungall, Christopher J. Cavalleri, Emanuele Fontana, Tommaso Valentini, Giorgio Mesiti, Marco Gillenwater, Lucas A. Santangelo, Brook Vasilevsky, Nicole A. Hoehndorf, Robert Bennett, Tellen D. Ryan, Patrick B. Hripcsak, George Kahn, Michael G. Bada, Michael Baumgartner, William A. Hunter, Lawrence E. Computational Bioscience Program University of Colorado Anschutz Medical Campus AuroraCO80045 United States Department of Biomedical Informatics Columbia University Irving Medical Center New YorkNY10032 United States Computer Science Department Interdisciplinary Quantitative Biology University of Colorado Boulder BoulderCO80301 United States AnacletoLab Computer Science Department University of Milan 20122 Italy Intelligent Systems Program University of Pittsburgh PittsburghPA15260 United States Department of Physical Medicine and Rehabilitation School of Medicine University of Colorado Anschutz Medical Campus AuroraCO80045 United States Division of Environmental Genomics and Systems Biology Lawrence Berkeley National Laboratory BerkeleyCA94720 United States Semanticly Ltd Athens Greece Department of Biomedical Informatics University of Pittsburgh School of Medicine PittsburghPA15206 United States Laboratory of Systems Pharmacology Harvard Medical School BostonMA02115 United States Division of Translational Informatics University of New Mexico School of Medicine AlbuquerqueNM87131 United States SIB Swiss Institute of Bioinformatics Basel Switzerland Berlin Institute of Health at Charité-Universitatsmedizin Berlin10117 Germany ELLIS European Laboratory for Learning and Intelligent Systems Germany Department of Biomedical Informatics University of Colorado School of Medicine AuroraCO80045 United States Data Collaboration Center Critical Path Institute 1840 E River Rd. Suite 100 TucsonAZ85718 United States Computer Electrical and Mathematical Sciences & Engineering Division Computational Bioscience Research Center King Abdullah University of Science and Technology Thuwal23955-6900 Saudi Arabia Department of Pediatrics University of Colorado School of Medicine AuroraCO80045 United States Janssen Research and Development RaritanNJ08869 United States Division of General Internal Medicine University of Colorado School of Medicine A

Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face significant integration challenges. Knowledge graphs (KGs) are used to model complex phenomena, and methods exist to construct them automatically. However, tackling complex biomedical integration problems requires flexibility in the way knowledge is modeled. Moreover, existing KG construction methods provide robust tooling at the cost of fixed or limited choices among knowledge representation models. PheKnowLator (Phenotype Knowledge Translator) is a semantic ecosystem for automating the FAIR (Findable, Accessible, Interoperable, and Reusable) construction of ontologically grounded KGs with fully customizable knowledge representation. The ecosystem includes KG construction resources (e.g., data preparation APIs), analysis tools (e.g., SPARQL endpoints and abstraction algorithms), and benchmarks (e.g., prebuilt KGs and embeddings). We evaluated the ecosystem by systematically comparing it to existing open-source KG construction methods and by analyzing its computational performance when used to construct 12 large-scale KGs. With flexible knowledge representation, PheKnowLator enables fully customizable KGs without compromising performance or usability. © 2023, CC BY.

关键词： Ecosystems

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CARDIOCARE: An integrated platform for the management of elderly multimorbid patients with breast cancer therapy induced cardiac toxicity

CARDIOCARE: An integrated platform for the management of eld...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： G. Karanasiou L. Koumakis S. Sfakianakis G. Manikis G. Kalliatakis A. Antoniades L. Lakkas D. Mauri C. Cipolla K. Mazzocco A. Papakonstantinou G. Filippatos A. Constantinidou B. Šeruga C. Conti A. Bucur E. Pacella K. Marias M. Tsiknakis D.I. Fotiadis Unit of Medical Technology and Intelligent Information Systems University of Ioannina Ioannina Greece Foundation for Research and Technology - Hellas Institute of Computer Science Heraklion Crete Greece Computational Bio-Medicine Laboratory Institute of Computer Science Foundation for Research and Technology – Hellas Heraklion Greece Stremble Ventures Ltd Limassol Cyprus 2nd Department of Cardiology School of Medicine University of Ioannina Department of Medical Oncology University of Ioannina Greece Cardiology Division European Institute of Oncology Milan Italy Department for Breast Cancer Endocrine Tumors and Sarcoma Theme Cancer Karolinska University Hospital and the Department of Oncology-Pathology Karolinska Institute Stockholm Sweden Department of Cardiology National and Kapodistrian University of Athens School of Medicine Attikon University Hospital Athens Greece Bank of Cyprus Oncology Centre Bank of Cyprus Oncology Centre Nicosia Cyprus Department of Medical Oncology Institute of Oncology Ljubljana Ljubljana Slovenia Istituto di Management Sanitario S.r.l Milano Italy Philips Research Europe Eindhoven Netherlands European Society of Cardiology Brussels Belgium Department of Electrical and Computer Engineering Hellenic Mediterranean University Heraklion Crete Greece Medical Technology and Intelligent Information Systems University of Ioannina Ioannina Greece Biomedical Research Institute Foundation for Research and Technology – Hellas University Campus of Ioannina Greece

Breast cancer (BC) remains the most diagnosed cancer in women, accounting for 12% of new annual cancer cases in Europe and worldwide. Advances in surgery, radiotherapy and systemic treatment have resulted in improved clinical outcomes and increased survival rates in recent years. However, BC therapy-related cardiotoxicity, may severely impact short- and long-term quality of life and survival. This study presents the CARDIOCARE platform and its main components, which by integrating patient-specific data from different categories, data from patient-oriented eHealth applications and wearable devices, and by employing advanced data mining and machine learning approaches, provides the healthcare professionals with a valuable tool for effectively managing BC patients and preventing or alleviating treatment induced *** Relevance— Through the adoption of CARDIOCARE platform healthcare professionals are able to stratify patients for their risk for cardiotoxicity and timely apply adequate interventions to prevent its onset.

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Robust medical instrument segmentation challenge 2019

arXiv

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arXiv 2020年

作者： Roβ, Tobias Reinke, Annika Full, Peter M. Wagner, Martin Kenngott, Hannes Apitz, Martin Hempe, Hellena Filimon, Diana Mindroc Scholz, Patrick Tran, Thuy Nuong Bruno, Pierangela Arbelaéz, Pablo Bian, Gui-Bin Bodenstedt, Sebastian Bolmgren, Jon Lindström Bravo-Sánchez, Laura Chen, Hua-Bin González, Cristina Guo, Dong Halvorsen, Pål Heng, Pheng-Ann Hosgor, Enes Hou, Zeng-Guang Isensee, Fabian Jha, Debesh Jiang, Tingting Kirtac, Kadir Jin, Yueming Kletz, Sabrina Leger, Stefan Li, Zhixuan Maier-Hein, Klaus H. Ni, Zhen-Liang Riegler, Michael A. Schoeffmann, Klaus Shi, Ruohua Speidel, Stefanie Stenze, Michael Twick, Isabell Wang, Gutai Wang, Jiacheng Wang, Liansheng Wang, Lu Zhang, Yujie Zhou, Yan-Jie Zhu, Lei Wiesenfarth, Manuel Kopp-Schneider, Annette Müller-Stich, Beat P. Maier-Hein, Lena Heidelberg Germany University of Heidelberg Germany Heidelberg Germany Department of General Heidelberg University Hospital Visceral and Transplant Surgery Heidelberg Germany caresyntax Berlin Germany University of Chinese Academy Sciences Beijing China State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Beijing China SimulaMet Oslo Norway Tromsø Norway Oslo Norway School of Mechanical and Electrical Engineering University of Electronic Science and Technology of China Chengdu China Partner Site Dresden Heidelberg Germany Faculty of Medicine and University Hospital Carl Gustav Carus Technische Universität Dresden Dresden Germany Dresden Germany Universidad de Los Andes Bogotá Colombia Peking University Peking China Department of Computer Science School of Informatics Xiamen University Xiamen China Department of Computer Science and Engineering Chinese University of Hong Kong Hong Kong German Cancer Research Center Division of Biostatistics Heidelberg Germany Institute of Information Technology Klagenfurt University Austria

Intraoperative tracking of laparoscopic instruments is often a prerequisite for computer and roboticassisted interventions. While numerous methods for detecting, segmenting and tracking of medical instruments based on endoscopic video images have been proposed in the literature, key limitations remain to be addressed: Firstly, robustness, that is, the reliable performance of state-of-the-art methods when run on challenging images (e.g. in the presence of blood, smoke or motion artifacts). Secondly, generalization;algorithms trained for a specific intervention in a specific hospital should generalize to other interventions or institutions. In an effort to promote solutions for these limitations, we organized the Robust Medical Instrument Segmentation (ROBUST-MIS) challenge as an international benchmarking competition with a specific focus on the robustness and generalization capabilities of algorithms. For the first time in the field of endoscopic image processing, our challenge included a task on binary segmentation and also addressed multi-instance detection and segmentation. The challenge was based on a surgical data set comprising 10,040 annotated images acquired from a total of 30 surgical procedures from three different types of surgery. The validation of the competing methods for the three tasks (binary segmentation, multi-instance detection and multi-instance segmentation) was performed in three different stages with an increasing domain gap between the training and the test data. The results confirm the initial hypothesis, namely that algorithm performance degrades with an increasing domain gap. While the average detection and segmentation quality of the best-performing algorithms is high, future research should concentrate on detection and segmentation of small, crossing, moving and transparent instrument(s) (parts). Copyright © 2020, The Authors. All rights reserved.

关键词： Endoscopy

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Metamorphosis of discontinuity lines and rectification of magnetic flux avalanches in the presence of noncentrosymmetric pinning forces

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Physical Review B 2021年第22期103卷 224514-224514页

作者： M. Motta L. Burger Lu Jiang J. D. González Acosta Ž. L. Jelić F. Colauto W. A. Ortiz T. H. Johansen M. V. Milošević C. Cirillo C. Attanasio Cun Xue A. V. Silhanek B. Vanderheyden Departamento de Física Universidade Federal de São Carlos 13565-905 São Carlos São Paulo Brazil Montefiore Research Unit Department of Electrical Engineering and Computer Science Université de Liège 4000 Sart Tilman Belgium School of Aeronautics Northwestern Polytechnical University Xi'an 710072 China Facultad de Ingeniería Universidad del Magdalena Santa Marta Colombia Departement Fysica Universiteit Antwerpen Groenenborgerlaan 171 B-2020 Antwerpen Belgium Nokia Bell Labs Antwerp Belgium Department of Physics University of Oslo POB 1048 Blindern 0316 Oslo Norway CNR-SPIN c/o Università degli Studi di Salerno I-84084 Fisciano (Sa) Italy Dipartimento di Fisica “E.R. Caianiello” Università degli Studi di Salerno I-84084 Fisciano (Sa) Italy School of Mechanics Civil Engineering and Architecture and MIIT Key Laboratory of Dynamics and Control of Complex Systems Northwestern Polytechnical University Xi'an 710072 China Experimental Physics of Nanostructured Materials Q-MAT CESAM Université de Liège B-4000 Sart Tilman Belgium

Considering a noncentrosymmetric pinning texture composed of a square array of triangular holes, the magnetic flux penetration and expulsion are investigated experimentally and theoretically. A direct visualization of the magnetic landscape obtained using a magneto-optical technique on a Nb film is complemented by a multiscale numerical modeling. This combined approach allows the magnetic flux dynamics to be identified from the single flux quantum limit up to the macroscopic electromagnetic response. Within the theoretical framework provided by time-dependent Ginzburg-Landau simulations, an estimation of the in-plane current anisotropy is obtained and its dependence with the radius of the curvature of hole vertices is addressed. These simulations show that current crowding plays an important role in channeling the flux motion, favoring hole-to-hole flux hopping rather than promoting interstitial flux displacement in between the holes. The resulting anisotropy of the critical current density gives rise to a distinct pattern of discontinuity lines for increasing and decreasing applied magnetic fields, in sharp contrast to the invariable patterns reported for centrosymmetric pinning potentials. This observation is partially accounted for by the rectification effect, as demonstrated by finite-element modeling. At low temperatures, where magnetic field penetration is dominated by thermomagnetic instabilities, highly directional magnetic flux avalanches with a fingerlike shape are observed to propagate along the easy axis of the pinning potential. This morphology is reproduced by numerical simulations. Our findings demonstrate that anisotropic pinning landscapes and, in particular, ratchet potentials produce subtle modifications to the critical state field profile that are reflected in the distribution of discontinuity lines.

关键词： Flux pinning Magneto-optical effect Monolayer films Superconductors Finite-element method Landau-Ginzburg theory

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Editorial Special issue on approximate dynamic programming and reinforcement learning

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控制理论与应用（英文版） 2011年第3期 309-309页

作者： Silvia Ferrari Jagannathan Sarangapani Frank L. Lewis Laboratory for Intelligent Systems and Control(LISC)Department of Mechanical Engineering & Materials Science Box 90300 Duke University Durham NC 27708-0005 Department of Electrical & Computer Engineering University of Missouri-Rolla MO 65401 U.S.A. Automation and Robotics Research Institute The University of Texas at Arlington 7300 Jack Newell Blvd. S Ft. Worth Texas 76118-7115 U.S.A.

We are extremely pleased to present this special issue of the Journal of control Theory and *** dynamic programming (ADP) is a general and effective approach for solving optimal control and estimation problems by adapting to uncertain environments over *** optimizes the sensing objectives accrued over a future time interval with respect to an adaptive control law,conditioned on prior knowledge of the system,its state,and uncertainties.A numerical search over the present value of the control minimizes a Hamilton-Jacobi-Bellman (HJB) equation providing a basis for real-time,approximate optimal control.

关键词： reinforcement learning dynamic programming optimal control effective approach prior knowledge control Theory real-time control law problems special search future ADP basis

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Meshless approach based on MLS with additional constraints for large deformation analysis

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Journal of Physics: Conference Series 2021年第1期1743卷

作者： R. El Kadmiri Y. Belaasilia A. Timesli M. S. Kadiri Sultan Moulay Slimane University National School of Applied Sciences of Khouribga (ENSAK) Laboratory of Process Engineering Computer Science and Mathematics Bd Beni Amir BP 77 Khouribga Morocco Hassan II University of Casablanca National Higher School of Arts and Crafts of Casablanca (ENSAM Casablanca) Laboratory of Structural Engineering Intelligent Systems and Electrical Energy 150 Avenue Nile Sidi Othman Casablanca 20670 Morocco Hassan II University of Casablanca Faculty of Sciences of Ben M'Sik LIMAT Laboratory B. P 7955 Sidi Othman Casablanca Morocco

In the present work, we are interested to develop a meshless approach, based on the strong form MLS approximation with additional constraints, to solve the nonlinear elastic and elsto-plastic problems for regular and irregular distribution of points. We adopt a plastic behavior law based on the total deformation theory, which is very convenient when the physical nonlinearity is more important than the effect of irreversible process and the loading history. In plasticity, one encounters discontinuities of rigidity where the application of asymptotic developments seems difficult or impossible. To apply the Taylor series expansion, regularization methods have been adapted. The strong form MLS approximation allows us to avoid the inconvenient of the numerical integration, while the asymptotic developments help us to reduce the computation cost observed in the incremental law of plasticity and the iterative methods. For irregular points distribution, we can get an ill-posed least squares problems due to a singular moment matrix of MLS approximation. To avoid this difficulty, we propose a modified MLS approximation by introducing additional constraints which allows to increase the error functional used in the derivation of the shape functions.

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A coupled Meshless-FEM method based on strong form of Radial Point Interpolation Method (RPIM)

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Journal of Physics: Conference Series 2021年第1期1743卷

In this present work, we are implementing a novel hybrid method based on the coupling of RPIM in strong form and Finite Element Method (FEM). The basic idea is to ensure the coupling between the two methods through the collocation technique based on RPIM interpolation. This technique is used to evaluate the local equations of the problem at the interface between FEM and RPIM regions. We can avoid numerical integrations of a big part of nodes using the strong form of RPIM. Numerical studies show that this method gives reasonably accurate results consistent with the theory.

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