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International Congress on Image and Signal Processing, BioMedical Engineering and Informatics

作者： Zhaohua Lu Ning Gao Weiwei Zhou Jingjing Yang Jinglong Wu Qi Li School of Computer Science and Technology Changchun University of Science and Technology Changchun P.R. China Graduate School of Natural Science and Technology Okayama University 3-1-1 Tsushima-naka Okayama Japan

Some studies about face recognition showed the human face with more relevant to oneself induces larger amplitude ERPs than the famous face. The famous face stimulus has been used to the P300-speller paradigm and improved the performance of P300-speller system. In our study, we designed a novel P300-speller paradigm using familiar face as stimulus, and the famous face P300-speller paradigm was as the control paradigm. We compared the ERPs and the classification accuracy between the two paradigms. The results showed that larger ERPs amplitude in the proposed paradigm than that in the control paradigm, and the average classification of proposed paradigm was greater than that in the control paradigm, while we didn't find the significant difference for classification accuracy between the two paradigms.

关键词： Face recognition Faces Electroencephalography Electrodes Electric potential Band-pass filters Scalp

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A multi-tab website fingerprinting aack 34

A multi-tab website fingerprinting aack

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34th Annual computer Security Applications Conference, ACSAC 2018

作者： Xu, Yixiao Wang, Tao Li, Qi Gong, Qingyuan Chen, Yang Jiang, Yong Graduate School at Shenzhen and Department of Computer Science Tsinghua University China Department of Computer Science and Engineering Hong Kong University of Science and Technology Hong Kong School of Computer Science Fudan University China

ISBN: (纸本)9781450365697

In a Website Fingerprinting (WF) attack, a local, passive eavesdropper utilizes network flow information to identify which web pages a user is browsing. Previous researchers have extensively demonstrated the feasibility and effectiveness of WF, but only under the strong Single Page Assumption: the network flow extracted by the adversary always belongs to a single page. In other words, the WF classifier will never be asked to classify a network flow corresponding to more than one page, or part of a page. The Single Page Assumption is unrealistic because people often browse with multiple tabs. When this happens, the network flow induced by multiple tabs will overlap, and current WF attacks fail to classify correctly. Our work demonstrates the feasibility of WF with the relaxed Single Page Assumption: we can attack a client who visits more than one pages simultaneously. We propose a multi-tab website fingerprinting attack that can accurately classify multi-tab web pages if they are requested and sequentially loaded over a short period of time. In particular, we develop a new BalanceCascade-XGBoost scheme for an attacker to identify the start point of the second page such that the attacker can accurately classify and identify these multi-tab pages. By developing a new classifier, we only use a small chunk of packets, i.e., packets between the first page's start time to the second page's start time, to fingerprint website. Our experiments demonstrate that in the multi-tab scenario, WF attacks are still practically effective. We have an average TPR of 92.58% on SSH, and we can also averagely identify the page with a TPR of 64.94% on Tor. Specially, compared with previous WF classifiers, our attack achieves a significantly higher true positive rate using a restricted chunk of packets. © 2018 Association for Computing Machinery.

关键词： Websites

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Model of Web Based Application to Control Bridge Traveler Using Raspberry Pi 3

Model of Web Based Application to Control Bridge Traveler Us...

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3rd International Conference on computer science and Computational Intelligence, ICCSCI 2018

作者： Wisnusenna, Sebastian Yonatan, Michael Sunardy Wibisurya, Aswin Fanny Yuwono, Teguh Computer Science Program Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Mobile Appication and Technology Program Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Struktur Pintar Indonesia Jakarta12950 Indonesia

Bridge traveler is used to facilitate the construction and maintenance of a bridge which is controlled using control panel buttons, located inside the traveler. However, this method leads to some problems, like a difficulty of moving a traveler to a proper position (perspective) and an inhibition of work due to damaged control panel. In this research, a model of a web-based application to control a traveler with spans by using Raspberry Pi is developed. This research's contribution is a model of a web-based application for traveler automation in all possible movements of its components. As the results, the experiments show that the program implemented doesn't take much time and the execution of a command is done in a reasonable time. Moreover, for the safety of the bridge traveler, this program also implements a sensor that works when a component is at its most downward/inward position and detecting a blocking object in the middle of a possible movement and stops the movement immediately. © 2018 The Authors. Published by Elsevier Ltd.

关键词： Internet of things

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Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock

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The American journal of Chinese medicine 2024年第4期52卷 1173-1193页

作者： Pei-Fang Lai Ramasamy Mahendran Bruce Chi-Kang Tsai Cheng-You Lu Chia-Hua Kuo Kuan-Ho Lin Shang-Yeh Lu Yu-Ling Wu Yung-Ming Chang Wei-Wen Kuo Chih-Yang Huang Department of Emergency Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation Hualien 970 Taiwan. Department of Medicine Tzu Chi University Hualien 970 Taiwan. Cardiovascular and Mitochondrial Related Disease Research Center Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation Hualien 970 Taiwan. Department of Post-Baccalaureate Medicine College of Medicine National Chung Hsing University Taichung 402 Taiwan. Laboratory of Exercise Biochemistry University of Taipei Taipei 111 Taiwan. Institute of Sports Sciences University of Taipei Taipei 111 Taiwan. School of Physical Education and Sports Science Soochow University Suzhou 215021 China. Department of Kinesiology and Health College of William and Mary Williamsburg VA 23185 USA. Department of Emergency Medicine China Medical University Hospital Taichung 404 Taiwan. College of Medicine China Medical University Taichung 406 Taiwan. Division of Cardiovascular Medicine Department of Internal Medicine China Medical University Hospital Taichung 404 Taiwan. The School of Chinese Medicine for Post-Baccalaureate I-Shou University 840 Kaohsiung Taiwan. Chinese Medicine Department E-DA Hospital Kaohsiung 824 Taiwan. 1PT Biotechnology Co. Ltd. Taichung 433 Taiwan. Department of Biological Science and Technology College of Life Sciences China Medical University Taichung 406 Taiwan. Ph.D. Program for Biotechnology Industry China Medical University Taichung 406 Taiwan. School of Pharmacy China Medical University Taichung 406 Taiwan. Graduate Institute of Biomedical Sciences China Medical University Taichung 406 Taiwan. Department of Medical Laboratory Science and Biotechnology Asia University Taichung 413 Taiwan. Center of General Education Buddhist Tzu Chi Medical Foundation Tzu Chi University of Science and Technology Hualien 970 Taiwan. Department of Medical Research China Medical University Hospital China Medical University Taichung 404 Taiwan.

Heat shock proteins (HSPs), which function as chaperones, are activated in response to various environmental stressors. In addition to their role in diverse aspects of protein production, HSPs protect against harmful protein-related stressors. Calycosin exhibits numerous beneficial properties. This study aims to explore the protective effects of calycosin in the heart under heat shock and determine its underlying mechanism. H9c2 cells, western blot, TUNEL staining, flow cytometry, and immunofluorescence staining were used. The time-dependent effects of heat shock analyzed using western blot revealed increased HSP expression for up to 2[Formula: see text]h, followed by protein degradation after 4[Formula: see text]h. Hence, a heat shock damage duration of 4[Formula: see text]h was chosen for subsequent investigations. Calycosin administered post-heat shock demonstrated dose-dependent recovery of cell viability. Under heat shock conditions, calycosin prevented the apoptosis of H9c2 cells by upregulating HSPs, suppressing p-JNK, enhancing Bcl-2 activation, and inhibiting cleaved caspase 3. Calycosin also inhibited Fas/FasL expression and activated cell survival markers (p-PI3K, p-ERK, p-Akt), indicating their cytoprotective properties through PI3K/Akt activation and JNK inhibition. TUNEL staining and flow cytometry confirmed that calycosin reduced apoptosis. Moreover, calycosin reversed the inhibitory effects of quercetin on HSF1 and Hsp70 expression, illustrating its role in enhancing Hsp70 expression through HSF1 activation during heat shock. Immunofluorescence staining demonstrated HSF1 translocation to the nucleus following calycosin treatment, emphasizing its cytoprotective effects. In conclusion, calycosin exhibits pronounced protective effects against heat shock-induced damages by modulating HSP expression and regulating key signaling pathways to promote cell survival in H9c2 cells.

关键词： Astragalus Membranaceus Calycosin Cardiomyocyte Heart Protection Heat Shock Heat Shock-Related Protein

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Theoretical identification of thermostabilizing amino acid mutations for G-protein-coupled receptors

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Biophysical Reviews 2020年第2期12卷 323-332页

作者： Murata, Takeshi Yasuda, Satoshi Hayashi, Tomohiko Kinoshita, Masahiro Graduate School of Science Chiba University 1-33 Yayoi-cho Inage Chiba 263-8522 Japan Molecular Chirality Research Center Chiba University 1-33 Yayoi-cho Inage Chiba 263-8522 Japan Institute of Advanced Energy Kyoto University Uji Kyoto 611-0011 Japan Present address: Interdisciplinary Program of Biomedical Engineering Assistive Technology and Art and Sports Sciences Faculty of Engineering Niigata University 8050 Ikarashi 2-no-cho Nishi-ku Niigata 950-2181 Japan

Thermostabilization of a membrane proteins, especially G-protein-coupled receptors (GPCRs), is often necessary for biochemical applications and pharmaceutical studies involving structure-based drug design. Here we review our theoretical, physics-based method for identifying thermostabilizing amino acid mutations. Its novel aspects are the following: The entropic effect originating from the translational displacement of hydrocarbon groups within the lipid bilayer is treated as a pivotal factor;a reliable measure of thermostability is introduced and a mutation which enlarges the measure to a significant extent is chosen;and all the possible mutations can be examined with moderate computational effort. It was shown that mutating the residue at a position of N_BW = 3.39 (N_BW is the Ballesteros-Weinstein number) to Arg or Lys leads to the stabilization of significantly many different GPCRs of class A in the inactive state. Up to now, we have been successful in stabilizing several GPCRs and newly solving three-dimensional structures for the muscarinic acetylcholine receptor 2 (M2R), prostaglandin E receptor 4 (EP4), and serotonin 2A receptor (5-HT_2AR) using X-ray crystallography. The subjects to be pursued in future studies are also discussed. © 2020, International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany, part of Springer Nature.

关键词： G-protein-coupled receptor Integral equation theory Lipid bilayer Membrane protein Morphometric approach Protein folding Solvation thermodynamics Thermostabilizing mutation

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Bioinformatics Pathway Analysis Pipeline for NGS Transcriptome Profile Data on Nasopharyngeal Carcinoma

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IOP Conference Series: Earth and Environmental science 2021年第1期794卷

作者： Digdo Sudigyo Gisti Rahmawati Dicka W. Setiasari Risky H. Poluan Tjeng Wawan Cenggoro Arif Budiarto Alam Ahmad Hidayat Sri R. Indrasari Afiahayati Sofia M. Haryana Bens Pardamean Bioinformatics & Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480 Study Program of Biotechnology Gadjah Mada University Yogyakarta Indonesia 55281 Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia 11480 Faculty of Medicine Public Health and Nursing Gadjah Mada University Yogyakarta Indonesia 55281 Department of Computer Science and Electronics Faculty of Mathematics and Natural Science Gadjah Mada University Yogyakarta Indonesia 55281 Computer Science Department BINUS Graduate Program - Master of Computer Science Program Bina Nusantara University Jakarta Indonesia 11480

Next-Generation Sequencing (NGS)-based genomics data have a huge potential to be used in transcriptomic profiling of Nasopharyngeal Carcinoma (NPC) to study the biosynthesis mechanism behind it. The high dimensionality of NGS data is the main challenge in performing the data analysis to extract useful information. In this workflow pipeline, memory-efficient Linux-based software such as HISAT2 and HTSeq are utilized to process the raw NGS data. Furthermore, Differential Expression Gene (DEG) list can be obtained by performing advanced analysis to the aligned Ribonucleic Acid (RNA) sequence using the edgeR protocol. This DEG list is one of the main inputs of biological pathway analysis that can be done in DAVID and PANTHER web-based software. Both tools generate a different pathway result related to inflammation.

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Thermal Conductivity of BAs under Pressure

arXiv

引用

arXiv 2021年

作者： Hou, Songrui Sun, Bo Tian, Fei Cai, Qingan Xu, Youming Wang, Shanmin Chen, Xi Ren, Zhifeng Li, Chen Wilson, Richard B. Materials Science and Engineering University of California RiversideCA92521 United States Tsinghua Shenzhen International Graduate School Tsinghua University Guangdong Shenzhen518055 China School of Materials Science and Engineering Sun Yat-sen University Guangdong Guangzhou510275 China Department of Physics Texas Center for Superconductivity University of Houston HoustonTX77204 United States Department of Mechanical Engineering University of California RiversideCA92521 United States Department of Electrical and Computer Engineering University of California RiversideCA92521 United States Department of Physics Southern University of Science and Technology Guangdong Shenzhen518055 China

The thermal conductivity of boron arsenide (BAs) is believed to be influenced by phonon scattering selection rules due to its special phonon dispersion. Compression of BAs leads to significant changes in phonon dispersion, which allows for a test of first principles theories for how phonon dispersion affects three- and four-phonon scattering rates. This study reports the thermal conductivity of BAs from 0 to 30 GPa. Thermal conductivity vs. pressure of BAs is measured by time-domain thermoreflectance with a diamond anvil cell. In stark contrast to what is typical for nonmetallic crystals, BAs is observed to have a pressure independent thermal conductivity below 30 GPa. The thermal conductivity of nonmetallic crystals typically increases upon compression. The unusual pressure independence of BAs’s thermal conductivity shows the important relationship between phonon dispersion properties and three- and four-phonon scattering rates. © 2021, CC BY.

关键词： Thermal conductivity

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Classification of the Structural Integrity by the General Vibration Method

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Procedia computer science 2019年 157卷 382-387页

作者： Fergyanto E. Gunawan Benfano Soewito Nico Surantha Tuga Mauritsius Nobumasa Sekishita Industrial Engineering Department BINUS Graduate Program - Master of Industrial Engineering Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480 Information Systems Information Department BINUS Graduate Program - Master of Information Systems Management Bina Nusantara University Jakarta Indonesia 11480 Department of Mechanical Engineering Toyohashi University of Technology Toyohashi Aichi 441-8580 Japan

Traditionally, for the purpose of classifying the integrity of an engineering structure, one may use the information of the natural frequencies or mode shapes or some other measures derived from the two. In this research, we propose a classification method on the basis of the general vibration model. The general vibration model is essentially a set of differential equations describing the dynamics of the structure under consideration. For the purpose of damage detection, a deviation of the general vibration model from the dynamic equilibrium point marks the occurrence of the damage. To demonstrate the effectiveness of the method, we study two simplest dynamical systems consisting of one- and two-concentrated masses subjected to a prescribed dynamic load. The structural damages are introduced artificially by reducing the stiffness of spring in the structures. We find that the general vibration model is more sensitive to damages than the traditional methods.

关键词： General Vibration Model Structural Integrity Structural Health Monitoring Power Spectral Density Damage Index

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Effects of galaxy environment on merger fraction?

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Astronomy and Astrophysics 2024年 686卷

作者： Pearson, W.J. Santos, D.J.D. Goto, T. Huang, T.-C. Kim, S.J. Matsuhara, H. Pollo, A. Ho, S.C.-C. Hwang, H.S. Malek, K. Nakagawa, T. Romano, M. Serjeant, S. Suelves, L.E. Shim, H. White, G.J. National Centre for Nuclear Research Pasteura 7 Warszawa02-093 Poland Max Planck Institute for Extraterrestrial Physics Gießenbachstraße 1 Garching85748 Germany Institute of Astronomy National Tsing Hua University 101 Section 2. Kuang-Fu Road Hsinchu30013 Taiwan Department of Space and Astronautical Science Graduate University for Advanced Studies SOKENDAI Shonankokusaimura Hayama Miura District Kanagawa240-0193 Japan Institute of Space and Astronautical Science Japan Aerospace Exploration Agency 3-1-1 Yoshinodai Chuo-ku Kanagawa Sagamihara252-5210 Japan Research School of Astronomy and Astrophysics The Australian National University CanberraACT2611 Australia Centre for Astrophysics and Supercomputing Swinburne University of Technology PO Box 218 HawthornVIC3122 Australia OzGrav The Australian Research Council Centre of Excellence for Gravitational Wave Discovery HawthornVIC3122 Australia ASTRO3D The Australian Research Council Centre of Excellence for All-sky Astrophysics in 3D CanberraACT2611 Australia Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of INAF – Osservatorio Astronomico di Padova Vicolo dell’Osservatorio 5 Padova35122 Italy School of Physical Sciences The Open University Walton Hall Milton KeynesMK7 6AA United Kingdom Department of Earth Science Education Kyungpook National University 80 Daehak-ro Buk-gu Daegu41566 Korea Republic of Space Science and Technology Division RALSpace STFC Rutherford Appleton Laboratory Chilton DidcotOX11 0QX United Kingdom

Aims. In this work we examine how environment influences the merger fraction, from the low density field environment to higher density groups and clusters. We also study how the properties of a group or cluster, as well as the position of a galaxy in the group or cluster, influences the merger fraction. Methods. We identified galaxy groups and clusters in the North Ecliptic Pole using a friends-of-friends algorithm and the local density. Once identified, we determined the central galaxies, group radii, velocity dispersions, and group masses of these groups and clusters. Merging systems were identified with a neural network as well as visually. With these identifications and properties of groups and clusters and merging galaxy identifications, we examined how the merger fraction changes as the local density changes for all galaxies as well as how the merger fraction changes as the properties of the groups or clusters change. Results. We find that the merger fraction increases as local density increases and decreases as the velocity dispersion increases, as is often found in the literature. A decrease in merger fraction as the group mass increases is also found. We also find that groups with larger radii have higher merger fractions. The number of galaxies in a group does not influence the merger fraction. Conclusions. The decrease in merger fraction as group mass increases is a result of the link between group mass and velocity dispersion. Hence, this decrease in merger fraction with increasing mass is a result of the decrease of merger fraction with velocity dispersion. The increasing relation between group radii and merger fraction may be a result of larger groups having smaller velocity dispersion at a larger distance from the centre or larger groups hosting smaller, infalling groups with more mergers. However, we do not find evidence of smaller groups having higher merger fractions. c The Authors 2024.

关键词： Galaxies

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Thermal conductivity of BAs under pressure

Research Square

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Research Square 2021年

作者： Hou, Songrui Sun, Bo Tian, Fei Cai, Qingan Xu, Youming Wang, Shanmin Peng, Wanyue Chen, Xi Ren, Zhifeng Li, Chen Wilson, Richard Materials Science and Engineering University of California RiversideCA92521 United States Tsinghua Shenzhen International Graduate School Tsinghua University Guangdong Shenzhen518055 China School of Materials Science and Engineering Sun Yat-sen University Guangdong Guangzhou510275 China Department of Physics Texas Center for Superconductivity University of Houston HoustonTX77204 United States Department of Mechanical Engineering University of California RiversideCA92521 United States Department of Electrical and Computer Engineering University of California RiversideCA92521 United States Department of Physics Southern University of Science and Technology Guangdong Shenzhen518055 China

Boron arsenide (BAs) is an ultrahigh-thermal-conductivity material with special phonon-phonon scattering behaviors. At ambient pressure, the bunching of acoustic phonon branches in BAs is believed to result in a small phase space for three-phonon scattering. Density functional theory predicts that this acoustic phonon bunching effect is sensitive to pressure and leads to an unusual pressure dependence of thermal conductivity. To explore this physics, we measure the thermal conductivity of BAs from 0 to 25 GPa using time-domain thermoreflectance in a diamond anvil cell. We characterized two BAs samples with ambient thermal conductivities of 350 and 480 W m-1 K-1. Our experiments show that the thermal conductivity of both samples depends weakly on pressure from 0 to 25 GPa. We attribute the weak pressure dependence of the thermal conductivity of BAs to the weak pressure dependence of total phonon-phonon scattering rates. Our experimental results are consistent with DFT predictions that three-phonon scattering rates increase from 0 to 25 GPa, while four-phonon scattering rates decrease. © 2021, CC BY.

关键词： Thermal conductivity

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