This book constitutes the refereed proceedings of the 10th International Conference on Economics of Grids, Clouds, Systems, and Services, GECON 2013, held in Zaragoza, Spain, in September *** 20 revised full papers pr...
详细信息
ISBN:
(数字)9783319024141
ISBN:
(纸本)9783319024134
This book constitutes the refereed proceedings of the 10th International Conference on Economics of Grids, Clouds, Systems, and Services, GECON 2013, held in Zaragoza, Spain, in September *** 20 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers are organized in the following topical sections: business models, energy consumption, resource allocation, work in progress on resource allocation, work in progress on pricing, quality of service, work in progress on utility and ROI modeling.
Single-cell RNA sequencing (scRNA-seq) has provided a high-dimensional catalog of millions of cells across species and diseases. These data have spurred the development of hundreds of computational tools to derive nov...
Single-cell RNA sequencing (scRNA-seq) has provided a high-dimensional catalog of millions of cells across species and diseases. These data have spurred the development of hundreds of computational tools to derive novel biological insights. Here, we outline the components of scRNA-seq analytical pipelines and the computational methods that underlie these steps. We describe available methods, highlight well-executed benchmarking studies, and identify opportunities for additional benchmarking studies and computational methods. As the biochemical approaches for single-cell omics advance, we propose coupled development of robust analytical pipelines suited for the challenges that new data present and principled selection of analytical methods that are suited for the biological questions to be addressed.
作者：
MOTHERWAY, D.L.HELLER, S.R.D. L. Motherway received his Bachelor of Science Degree in Mechanical Engineering from the University of Rhode Island in June 1961. He was subsequently employed at General Dynamics/Electric Boat Division
Groton Connecticut where he held positions in their Planning Department as a planning engineer for FBM Submarine Construction and in the Mechanical Division as a design engineer. Motherway went to the Naval Ship Engineering Center Washington D. C. in March of 1966 with the Submarine Hydraulics Section of the Hull Design Branch where he participated in the design of submarine hydraulic systems. He later transferred to the Ocean Engineering Section of the Deck Systems Branch where he participated in design related to deep submergence vehicles and ocean salvage and retrieval systems. During this period at NavSEC he received his Master Science Degree in Mechanical Engineering from the Catholic University of America Washington D. C. From April 1970 to May 1971 he was with the Undersea Long-Range Missile System (ULMS) Submarine Design Development Office in the capacity of Assistant Subsystem Design Director. Currently he is the Senior Project Engineer for the ULMS program at the office of the Supervisor of Shipbuilding Conversion and Repair Groton Connecticut. He is a member of ASNE and ASE. S. R. Heller
Jr. a retired Engineering Duty Officer of the United States Navy received his undergraduate education at the University of Michigan in Naval Architecture and Marine Engineering and in Mathematics. Following typical shipyard duty during World War II he received postgraduate instruction at the Massachusetts Institute of Technology leading to the degrees of Naval Engineer and Doctor of Science in Naval Architecture. Since then he has had design responsibilities in the Bureau of Ships had a maintenance assignment with the Fleet directed structural research at the David Taylor Model Basin engaged in submarine design and construction at Portsmouth Naval Shipyard and was the last Head of Hull Design in the
The comparative heaving characteristics of two unusual ship configurations, a spar‐type ship similar to FLIP and a catamaran which employs a submerged cradle suspended by sophisticated motion attenuation devices, for...
Simulation-based methods for statistical inference have evolved dramatically over the past 50 years, keeping pace with technological advancements. The field is undergoing a new revolution as it embraces the representa...
Simulation-based methods for statistical inference have evolved dramatically over the past 50 years, keeping pace with technological advancements. The field is undergoing a new revolution as it embraces the representational capacity of neural networks, optimization libraries, and graphics processing units for learning complex mappings between data and inferential targets. The resulting tools are amortized, in the sense that, after an initial setup cost, they allow rapid inference through fast feed-forward operations. In this article we review recent progress in the context of point estimation, approximate Bayesian inference, summary-statistic construction, and likelihood approximation. We also cover software and include a simple illustration to showcase the wide array of tools available for amortized inference and the benefits they offer over Markov chain Monte Carlo methods. The article concludes with an overview of relevant topics and an outlook on future research directions.
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