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RSC Applied Polymers 2024年第1期3卷 247-256页

作者： Khairkkar, Shhyam Pansare, Amol V. Pansare, Shubham V. Chhatre, Shraddha Y. Sakamoto, Junji Barbezat, Michel Terrasi, Giovanni P. Patil, Vishwanath R. Nagarkar, Amit A. Naito, Masanobu Data-Driven Polymer Design Group Research and Services Division of Materials Data and Integrated System (MaDIS) National Institute for Materials Science (NIMS) 1-2-1 Sengen Ibaraki Tsukuba 305-0047 Japan Composites Group Mechanical Systems Engineering Swiss Federal Laboratories for Materials Science and Technology-Empa ETH Domain Dübendorf 8600 Switzerland Department of Chemistry University of Mumbai Santacruz (E) Mumbai 400098 India National Chemical Laboratory (NCL) Dr Homi Bhabha Road Pune 411008 India Advanced Material Technology Center Technology Division Panasonic Holdings Corporation 1006 Kadoma Kadoma City Osaka 571-8508 Japan Datacule Inc. 529 Main St. Boston 02129 MA United States

We show that dynamic covalent exchange at the interface of two thermosetting polymers results in strong bonding between the materials via creation of a new material at the interface. Thus, polymers of significantly different polarities can be bonded without the use of adhesives. We also show that such dynamic covalent exchange is not only limited to the interface but also penetrates into the bulk material (ca. 20 microns), thereby creating a strong bond. The creation of a new material at the interface was confirmed by Energy Dispersive X-ray (EDX) elemental mapping as well as a new glass transition temperature at the interface. Using this phenomenon, we show that hydrophobic, compliant polymers can also be used as adhesives for polar, stiff materials. We also show that such dynamic exchange also takes place in the presence of fillers like nano-silica. Lastly, using this technique, we demonstrate the adhesive-less fabrication of layered materials where each layer has vastly different polarities and mechanical properties, thereby tuning the failures modes of the resulting composite material. © 2025 RSC.

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Anomaly Detection for Stochastic Networked Cyber-Physical systems: A Statistical Approach

Anomaly Detection for Stochastic Networked Cyber-Physical Sy...

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International Conference on Control and Automation (ICCA)

作者： Yamin Yan Minyue Fu Maria M. Seron School of Electrical and Electronic Engineering Nanyang Technological University Singapore Shenzhen Key Laboratory of Control Theory and Intelligent Systems and Centre for Control Science and Technology School of System Design and Intelligent Manufacturing Southern University of Science and Technology Shenzhen China School of Engineering The University of Newcastle Callaghan NSW Australia

ISBN: (数字)9798350354409

ISBN: (纸本)9798350354416

In this paper, we investigate the anomaly detection problem within stochastic networked cyber-physical systems. We introduce an anomaly detection scheme centered on estimator design employing a statistical approach. Specifically, we extend the statistical method recently developed for single systems to networked control scenarios. Additionally, we analyse the detection of several representative anomalies through this statistical approach. We then apply our anomaly detection strategy to a power network system exposed to such anomalies. Our findings demonstrate that the proposed design effectively detects these anomalies, which simpler methods relying solely on residual assessment with a threshold fail to identify.

关键词： Analytical models Automation Statistical analysis Stochastic processes Cyber-physical systems Control systems Anomaly detection

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Verification of the 2D/1D coupling 3D transport code TIGER with C5G7 benchmarks

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International Journal of Advanced Nuclear reactor design and technology 2019年 1卷 43-50页

作者： Wu, Wenbin Yu, Yingrui Li, Qing Yao, Dong Luo, Qi Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China Chengdu610213 China

TIGER is a 2D/1D coupling 3D transport code developed by Nuclear Power Institute of China based on large-scale parallel computation. It employs 2D domain-decomposed parallel Matrix MOC in the radial direction and 1D finite difference diffusion in the axial direction. 2D domain-decomposed parallel Matrix MOC is accelerated with multi-group and multi-domain coupled PGMRES algorithm. Generally, 2D planar problem are solved independently and parallel degree is natural in the axial direction. Combination of the parallel degrees of both radial and axial directions is adopted in TIGER to achieve the large-scale parallel computation. In this paper, a few variations of C5G7 benchmarks were created based on the published benchmarks. Reference results of these variations were provided by the Monte Carlo code RMC. To demonstrate the accuracy and efficiency of TIGER, C5G7 benchmarks and these relevant variations were calculated by TIGER, and the comparisons were made with the published results and Monte Carlo results. © 2019 Xi'an Jiaotong University

关键词： Matrix algebra

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Experimental Study on Droplet Behavior and Mechanisms During Reflooding in a Single-Rod Channel

SSRN

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SSRN 2022年

作者： Chen, Mingjing Liu, Hanzhou Chen, Deqi Zhong, Lei Liu, Haidong Yu, Hongxing Yu, Ruan Feng, Peng Key Laboratory of Low-grade Energy Utilization Technologies and Systems Chongqing University Ministry of Education Chongqing 400044 China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China Chengdu610041 China Key Laboratory of Aerospace Thermophysics Ministry of Industry and Information Technology School of Energy Science and Engineering Harbin Institute of Technology Harbin150001 China

Discrete droplets have received extensive attention in reflooding processes under Loss Of Coolant Accident (LOCA) conditions due to their large vapor-liquid interface area, droplet collision, droplet evaporation, and other behaviors that have a significant impact on the heat transfer of Dispersed Flow Film Boiling (DFFB). Unfortunately, the accurate prediction of the characteristics of droplet velocity and distribution under DFFB cannot be achieved at present, due to the lack of sufficient visual data support. For this reason, a visualization experiment of high-temperature surface reflooding in a single-rod channel was carried out. In this paper, the effect of the thermal parameter, such as input heat flux on the transient droplet behavior, which include the droplet size and velocity, has been analaysed in detail. Furthermore, to provide physical support for building droplet distribution models containing more physical mechanisms in the future, several droplet formation and breakup mechanisms, which include the Helmholtz instability, capillary breakage and rewetting area sputter, has been discussed in this paper. © 2022, The Authors. All rights reserved.

关键词： Drop breakup

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Capillary Limit of a Sodium Screen-Wick Heat Pipe

SSRN

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SSRN 2022年

作者： Ma, Yugao Wang, Xueqing Yu, Hongxing Huang, Shanfang Zhang, Yingnan Huang, Jian Su, Guanghui Deng, Jian Chai, Xiaoming Hu, Wenzhen School of Nuclear Science and Technology Xi’an Jiaotong University Shanxi Xi’an710049 China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China Chengdu610213 China Department of Engineering Physics Tsinghua University Beijing100084 China State Key Laboratory of Multiphase Flow in Power Engineering China

High-temperature alkali-metal heat pipes are passive heat transfer devices, where the capillary pressure created by the menisci in the wick pumps the condensed fluid back to the evaporator. Thus, the heat pipe heat transfer capacity is limited by the maximum capillary pressure at high heat fluxes. This work presents a two-dimensional heat and mass transfer model that includes the capillary and gravitational forces that are used to predict the capillary limit which is then validated by experimental data. The predicted critical heat flux temperature has an error of less than 20℃ and a relative error of 6%. The predicted transient sequences are consistent with the measurements. The model shows that capillary limit is affected by inclination angle, heat flux, and wick structure. For inclinations, the critical heat flux at the capillary limit is linearly related to the inclination angle with the predicted temperature rising 2 ~10℃/s during the early stage of the capillary limit critical heat flux condition. The evaporator temperature oscillates before the capillary limit with positive inclinations. For heat fluxes, increasing the heat flux by 17% increases the temperature increase rate 10 fold with a longer dryout length. The evaporator exhibits hysteresis after the capillary limit due to partial dryout of evaporator. For wick structures, reducing the mesh screen pitch from 80 μm to 15 μm reduces the critical heat flux to 10% of the CHF at 80 μm. This model can accurately predict the heat pipe temperature variations at the capillary limit and can explain the physical mechanisms for the dryout oscillations and recovery hysteresis at the capillary limit. Thus, the measurements and model provide analytical guidelines for designing heat pipe cooling systems. © 2022, The Authors. All rights reserved.

关键词： Heat flux

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Research on probabilistic safety assessment (PSA) method of safety class distributed control system (DCS) in nuclear power plant based on fuzzy Markov process

Research on probabilistic safety assessment (PSA) method of ...

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2020 International Conference on Nuclear Engineering, ICONE 2020, collocated with the ASME 2020 Power Conference

作者： Tian, Xufeng Hao, Yan Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China HuaFu avenue 299# section 3 Chengdu city610213 China

ISBN: (纸本)9780791883778

Safety class DCS(Distributed Control system) in nuclear power plant is characterized by multi-state interaction, complex function and unknown fault mechanism, which limits the use of tradition PSA(Probabilistic Safety Assessment) method such as event tree and fault tree. An improved dynamic probabilistic security simulation method is proposed based on fuzzy Markov process to quantitative evaluation the risk of Safety class DCS in nuclear power plant, which resolved the failure uncertainty problem without in-depth understanding of failure mechanism. Firstly, the fuzzy fault tree reliability evaluation model is established based on fuzzy theory and FTA(Fault Tree Analysis), which describes the probability and degree of failure with fuzzy number. Then, the fuzzy fault tree is transformed into fuzzy Markov chain, this model is described mathematically, and the reliability indexes are simulated and analyzed with Monte Carlo simulation method, the change of system safety performance in long-term operation is obtained. Finally, the scientificity and effectiveness is verified by the example of redundant analog output module of safety class DCS in nuclear plant. Copyright © 2020 ASME

关键词： Nuclear power plants

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ACCELERATED PERFORMANCE DEGRADATION TEST AND ANALYSIS OF HIGH-TEMPERATURE STRAIN GAUGES 13

ACCELERATED PERFORMANCE DEGRADATION TEST AND ANALYSIS OF HIG...

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13th International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering, QR2MSE 2023

作者： Li, Lu Wang, Zhihua Yang, Ning Wu, Qiong Wang, Hanyue Mao, Zelong Ren, Kunpeng Wang, Qiuyue Wang, Yifeng National Key Laboratory of Strength and Structural Integrity School of Aeronautic Science and Engineering Beihang University Beijing China Shenyang Aircraft Design and Research Institute Shenyang China Institute of Spacecraft System Engineering China Academy of Space Technology Beijing China Navigation Instrument Research Institute Tianjin China Beijing Institute of Control Engineering Beijing China

ISBN: (纸本)9781839539848

With the extension of the service time of the structure and the worse service temperature conditions, the drift problem of high-temperature strain gauges gradually becomes prominent. This research aims to address the issue of the drift of measurement results because of the performance degradation of high-temperature strain gauges, and investigate the drift law under different temperatures considering complex service environments. In this paper, a combination of experimental research and theoretical analysis is utilized to design and conduct the accelerated performance degradation test on high-temperature strain gauges. Based on the result of the test, an accelerated performance degradation model is developed using the Wiener process and Arrhenius model. Finally, estimation curves for the average value and percentile value of the performance parameters of the high-temperature strain gauges are obtained, which demonstrates that the established accelerated performance degradation model can reasonably describe the degradation law. Additionally, the established accelerated performance degradation model enables effective analysis and compensation of gauge drift at any temperature. © The Institution of Engineering & technology 2023.

关键词： Strain gages

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GeoReF: Geometric Alignment Across Shape Variation for Category-level Object Pose Refinement

arXiv

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arXiv 2024年

作者： Zheng, Linfang Tse, Tze Ho Elden Wang, Chen Sun, Yinghan Chen, Hua Leonardis, Aleš Zhang, Wei Chang, Hyung Jin Shenzhen Key Laboratory of Control Theory and Intelligent Systems School of System Design and Intelligent Manufacturing Southern University of Science and Technology China Department of Computer Science The University of Hong Kong Hong Kong School of Computer Science University of Birmingham United Kingdom

Object pose refinement is essential for robust object pose estimation. Previous work has made significant progress towards instance-level object pose refinement. Yet, category-level pose refinement is a more challenging problem due to large shape variations within a category and the discrepancies between the target object and the shape prior. To address these challenges, we introduce a novel architecture for category-level object pose refinement. Our approach integrates an HS-layer and learnable affine transformations, which aims to enhance the extraction and alignment of geometric information. Additionally, we introduce a cross-cloud transformation mechanism that efficiently merges diverse data sources. Finally, we push the limits of our model by incorporating the shape prior information for translation and size error prediction. We conducted extensive experiments to demonstrate the effectiveness of the proposed framework. Through extensive quantitative experiments, we demonstrate significant improvement over the baseline method by a large margin across all metrics. © 2024, CC BY-NC-SA.

关键词： Metadata

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Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase

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中国药理学报（英文版） 2022年第2期43卷 470-482页

作者： Wen Li Li-ping Liao Ning Song Yan-jun Liu Yi-luan Ding Yuan-yuan Zhang Xiao-ru Zhou Zhong-ya Sun Sen-hao Xiao Hong-bo Wang Jing Lu Nai-xia Zhang Hua-liang Jiang Kai-xian Chen Chuan-peng Liu Jie Zheng Ke-hao Zhao Cheng Luo School of Pharmacy Key Laboratory of Molecular Pharmacology and Drug Evaluation(Yantai University)Ministry of EducationCollaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of ShandongYantai UniversityYantai 264005China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China University of Chinese Academy of Sciences Beijing 100049China Center of Immunological Diseases Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Department of Gastroenterology Xinhua HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 201210China Department of Analytical Chemistry Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology Shanghai Tech UniversityShanghai 201210China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China School of Life Science and Technology Harbin Institute of TechnologyHarbin 200092China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchSha

Aerobic glycolysis,also known as the Warburg effect,is a hallmark of cancer cell glucose metabolism and plays a crucial role in the activation of various types of immune *** 3-phosphate dehydrogenase(GAPDH)catalyzes the conversion of D-glyceraldehyde 3-phosphate to D-glycerate 1,3-bisphosphate in the 6th critical step in *** exerts metabolic flux control during aerobic glycolysis and therefore is an attractive therapeutic target for cancer and autoimmune ***,GAPDH inhibitors were reported to function through common suicide inactivation by covalent binding to the cysteine catalytic residue of ***,by developing a high-throughput enzymatic screening assay,we discovered that the natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose(PGG)is an inhibitor of GAPDH with Ki=0.5 μ*** blocks GAPDH activity by a reversible and NAD+and Pi competitive mechanism,suggesting that it represents a novel class of GAPDH ***-depth hydrogen deuterium exchange mass spectrometry(HDX-MS)analysis revealed that PGG binds to a region that disrupts NAD+and inorganic phosphate binding,resulting in a distal conformational change at the GAPDH tetramer *** addition,structural modeling analysis indicated that PGG probably reversibly binds to the center pocket of ***,PGG inhibits LPS-stimulated macrophage activation by specific downregulation of GAPDH-dependent glucose consumption and lactate *** summary,PGG represents a novel class of GAPDH inhibitors that probably reversibly binds to the center pocket of *** study sheds new light on factors for designing a more potent and specific inhibitor of GAPDH for future therapeutic applications.

关键词： glyceraldehyde 3-phosphate dehydrogenase 1 2 3 4 6-penta-O-galloyl-β-D-glucopyranose hydrogen deuterium exchange mass spectrometry reversible inhibitor glycolysis

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Experimental Research on Uniaxial Tensile Behavior and Cyclic Deformation Behavior of TA17

Experimental Research on Uniaxial Tensile Behavior and Cycli...

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作者： Du, Juan Shao, Xuejiao Kuang, Linyuan Lu, Yuechuan Yu, Minda Lu, Jiang State Key Laboratory of Reactor System Design Technology Nuclear Power Institute of China Chengdu610213 China

Titanium alloys are widely used in various fields for its high strength, good corrosion resistance and high heat resistance. Many countries in the world have recognized the importance of titanium alloy materials, and have developed and applied them in practice. In order to accurately describe uniaxial tensile behavior and ratcheting behavior of material, a series of experiments of TA17 were conducted at room temperature and 350 ℃, including the uniaxial tensile experiments of TA17 with different processing techniques, the strain controlled cyclic experiments and the stress controlled cyclic experiments. The uniaxial tensile curves of materials with different processing techniques are discussed. The effects of different strain amplitudes of cyclic straining were analyzed. The effects of different combinations of mean stress and stress amplitude were analyzed. Finally, the uniaxial stress and strain curves with different processing techniques, cyclic stress and strain curves under different strain amplitudes and stress amplitude were obtained. The results show that the stress and strain curves of longitudinal plates and forgings are the lowest, while the stress and strain curves of transverse plates and bars are the highest. TA17 exhibited significant cyclic stability under different strain amplitudes and has obvious ratcheting behavior under asymmetric stress control. The obtained conclusions are helpful to improve the mechanical properties of TA17 and establish the cyclic constitutive model in the following work. © Springer Nature Switzerland AG 2020.

关键词： Corrosion resistance

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