Understanding the regulatory mechanisms of intestinal organoid morphogenesis remains a fundamental challenge in organoid biology. Emerging evidence highlights mechanical bistability as a critical regulator, mediated b...
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Understanding the regulatory mechanisms of intestinal organoid morphogenesis remains a fundamental challenge in organoid biology. Emerging evidence highlights mechanical bistability as a critical regulator, mediated by dynamic lumen-actomyosin feedback. The recently developed 3D vertex model demonstrates that crypt curvature modulates actomyosin localization via mechanosensitive pathways, creating two stable morphological states—bulged or budded—depending on mechanical history. This model advances beyond static vertex models by incorporating epithelial thickness variations and lumen pressure effects, explaining previously unresolved phenomena like irreversible crypt budding and snap-through transitions. The findings establish a new framework for understanding mechanical decision-making in epithelial tissues, with implications for organoid engineering and developmental biology.
Dear editor,In recent years, vertical and/or short take-off and landing(V/STOL) aircraft have attracted much attention because they combine the efficiency of fixed-wing vehicles with the flexibility of traditional ver...
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Dear editor,In recent years, vertical and/or short take-off and landing(V/STOL) aircraft have attracted much attention because they combine the efficiency of fixed-wing vehicles with the flexibility of traditional vertical take-off and landing aircraft,
Given a maneuvering control strategy for air-breathing hypersonic vehicle, which adopt the compound integrated flight/propulsion guidance and control method, further excavation the capability of scramjet to run stable...
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With the continuous improvement of radar intelligence, it is difficult for traditional countermeasures to achieve ideal results. In order to deal with complex, changeable, and unknown threat signals in the complex ele...
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With the continuous improvement of radar intelligence, it is difficult for traditional countermeasures to achieve ideal results. In order to deal with complex, changeable, and unknown threat signals in the complex electromagnetic environment, a waveform intelligent optimization model based on intelligent optimization algorithm is proposed. By virtue of the universality and fast running speed of the intelligent optimization algorithm, the model can optimize the parameters used to synthesize the countermeasure waveform according to different external signals, so as to improve the countermeasure *** algorithm(GA) and particle swarm optimization(PSO)are used to simulate the intelligent optimization of interruptedsampling and phase-modulation repeater waveform. The experimental results under different radar signal conditions show that the scheme is feasible. The performance comparison between the algorithms and some problems in the experimental results also provide a certain reference for the follow-up work.
This paper presents an approach for mitigating the cross-eye jamming using a dual-polarization array. By transmitting a sum beam and a difference beam in two orthogonal polarimetric channels, a synthesized transmitted...
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This paper presents an approach for mitigating the cross-eye jamming using a dual-polarization array. By transmitting a sum beam and a difference beam in two orthogonal polarimetric channels, a synthesized transmitted beam with spatially varying polarization is produced, such that the polarization of the transmitted radar wave varies in azimuth or elevation. Thus, the phases of the signals received on the two antennas of a cross-eye jammer become unequal, and an additional phase difference is introduced to disrupt the 180? phase shifting in the retrodirective loop of the jammer. By means of beam scanning in a small angular range,the optimal beam steering configuration can be found to maximize the phase error for the mitigation of cross-eye jamming. As a result, the jamming performance of the cross-eye jammer degrades largely. Theoretical analysis and simulation results indicate that the proposed method is valid and feasible.
In this paper, the model of a novel liquid-circular angular accelerometer is studied. Due to the absence of theoretical model of liquid-circular angular accelerometer, a subspace identification method(SIM) based on Ak...
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ISBN:
(纸本)9781509009107
In this paper, the model of a novel liquid-circular angular accelerometer is studied. Due to the absence of theoretical model of liquid-circular angular accelerometer, a subspace identification method(SIM) based on Akaike Information Criterion(AIC) is chosen for model identification of angular accelerometer. The proposed identification method is tested on a liquid-circular angular accelerometer prototype. The experimental results indicate that SIM could obtain a more accurate model than least square method, with a degree of fitting above 90%. In addition, SIM possesses good repeatability and stability. The experimental model identified by SIM in this paper can be applied in engineering practice.
Malicious code is characterized by a large number of types, rapid increase in number, continuous update of transmission routes, and continuous enhancement of back analysis and back detection methods. Therefore, how to...
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The flourish of deep learning frameworks and hardware platforms has been demanding an efficient compiler that can shield the diversity in both software and hardware in order to provide application *** the existing dee...
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The flourish of deep learning frameworks and hardware platforms has been demanding an efficient compiler that can shield the diversity in both software and hardware in order to provide application *** the existing deep learning compilers,TVM is well known for its efficiency in code generation and optimization across diverse hardware *** the meanwhile,the Sunway many-core processor renders itself as a competitive candidate for its attractive computational power in both scientific computing and deep learning *** paper combines the trends in these two ***,we propose swTVM that extends the original TVM to support ahead-of-time compilation for architecture requiring cross-compilation such as *** addition,we leverage the architecture features during the compilation such as core group for massive parallelism,DMA for high bandwidth memory transfer and local device memory for data locality,in order to generate efficient codes for deep learning workloads on *** experiment results show that the codes generated by swTVM achieve 1.79x improvement of inference latency on average compared to the state-of-the-art deep learning framework on Sunway,across eight representative *** work is the first attempt from the compiler perspective to bridge the gap of deep learning and Sunway processor particularly with productivity and efficiency in *** believe this work will encourage more people to embrace the power of deep learning and Sunwaymany-coreprocessor.
This paper investigates the consensus disturbance rejection problem among multiple high-order agents with directed *** on disturbance observers,distributed consensus disturbance rejection protocols are constructed in ...
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This paper investigates the consensus disturbance rejection problem among multiple high-order agents with directed *** on disturbance observers,distributed consensus disturbance rejection protocols are constructed in leaderless and leader-follower consensus *** from the previous related papers,the consensus protocols in this paper are developed in a fully distributed fashion,relying on only the state information of each agent and its *** conditions are provided to guarantee that the asymptotic stability of high-order multi-agent systems can be reached with matched disturbances.
Mass transport through the nanoporous medium is ubiquitous in nature and *** the macroscale transport phenomena which have been well understood by the theory of continuum mechanics,the relevant physics and mechanics o...
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Mass transport through the nanoporous medium is ubiquitous in nature and *** the macroscale transport phenomena which have been well understood by the theory of continuum mechanics,the relevant physics and mechanics on the nanoscale transport still remain *** developments in fabrication of slit-like nanocapillaries with precise dimensions and atomically smooth surfaces have promoted the fundamental research on the molecular transport under extreme *** this review,we summarized the contemporary progress in the study of confined molecular transport of water,ions and gases,based on both experiments and molecular dynamics *** liquid exhibits a pronounced layered structure that extends over several intermolecular distances from the solid surface,which has a substantial influence on static properties and transport behaviors under *** studies have also shown that those molecular details could provide some new understanding on the century-old classical theory in this field.
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