Learning causal structures from observational data is critical for causal discovery and many machine learning tasks. Traditional constraint-based methods first adopt conditional independence (CI) tests to learn a glob...
详细信息
Global Navigation Satellite System(GNSS)-based passive radar(GBPR)has been widely used in remote sensing ***,for moving target detection(MTD),the quadratic phase error(QPE)introduced by the non-cooperative target moti...
详细信息
Global Navigation Satellite System(GNSS)-based passive radar(GBPR)has been widely used in remote sensing ***,for moving target detection(MTD),the quadratic phase error(QPE)introduced by the non-cooperative target motion is usually difficult to be compensated,as the low power level of the GBPR echo signal renders the estimation of the Doppler rate less ***,the moving target in GBPR image is usually defocused,which aggravates the difficulty of target detection even *** this paper,a spawning particle filter(SPF)is proposed for defocused ***,the measurement model and the likelihood ratio function(LRF)of the defocused point-like target image are ***,a spawning particle set is generated for subsequent target detection,with reference to traditional particles in particle filter(PF)as their *** that,based on the PF estimator,the SPF algorithm and its sequential Monte Carlo(SMC)implementation are proposed with a novel amplitude estimation method to decrease the target state ***,the effectiveness of the proposed SPF is demonstrated by numerical simulations and pre-liminary experimental results,showing that the target range and Doppler can be estimated accurately.
High-temperature electronic ceramics are indispensable in applications such as the automotive sector, aerospace, oil exploration and other fields. Potassium sodium niobate-based (KNN-based) ceramics have emerged as cr...
详细信息
Ground-state cooling of the mechanical degree of freedom is a fundamental requirement for quantum state transfer between relevant optical and mechanical ***,we fabricate optomechanical crystal cavities with co-localiz...
详细信息
Ground-state cooling of the mechanical degree of freedom is a fundamental requirement for quantum state transfer between relevant optical and mechanical ***,we fabricate optomechanical crystal cavities with co-localized mechanical and optical modes on a monolithic *** typical linewidth of the optical modes at telecom wavelength is as low as 0.95 GHz,and the mechanical resonant frequency is around 5 GHz,which means the optomechanical system can be operated in the resolved sideband *** the statistics of the asymmetry in the scattering rates of red and blue detuning driving processes,we initialize and characterize the mechanical system in its quantum ground-state of motion,with a mean thermal phonon occupancy nth=0.018±0.0034,corresponding to a mode temperature of 57.3 m *** is a general platform for quantum state transfer between relevant optical and mechanical systems,as well as the quantum entanglement between these systems.
The quality of the exposed avionics solder joints has a significant impact on the stable operation of the inorbit ***,the previously reported inspection methods for multi-scale solder joint defects generally suffer lo...
详细信息
The quality of the exposed avionics solder joints has a significant impact on the stable operation of the inorbit ***,the previously reported inspection methods for multi-scale solder joint defects generally suffer low accuracy and slow detection ***,a novel real-time detector VMMAO-YOLO is demonstrated based on variable multi-scale concurrency and multi-depth aggregation network(VMMANet)backbone and“one-stop”global information gather-distribute(OS-GD)*** with infrared thermography technology,it can achieve fast and high-precision detection of both internal and external solder joint ***,VMMANet is designed for efficient multi-scale feature extraction,which mainly comprises variable multi-scale feature concurrency(VMC)and multi-depth feature aggregation-alignment(MAA)*** can extract multi-scale features via multiple fix-sized and deformable convolutions,while MAA can aggregate and align multi-depth features on the same order for feature *** allows the low-level features with more spatial details to be transmitted in depth-wise,enabling the deeper network to selectively utilize the preceding inference *** VMMANet replaces inefficient highdensity deep convolution by increasing the width of intermediate feature levels,leading to a salient decline in *** OS-GD is developed for efficacious feature extraction,aggregation and distribution,further enhancing the global information gather and deployment capability of the *** a self-made solder joint image data set,the VMMAOYOLO achieves a mean average precision mAP@0.5 of 91.6%,surpassing all the mainstream YOLO-series ***,the VMMAO-YOLO has a body size of merely 19.3 MB and a detection speed up to 119 frame per second,far superior to the prevalent YOLO-series detectors.
In clinical practice, technologies for automatically segmenting polyps might greatly improve the speed and accuracy of medical diagnosis, significantly reducing the chances of patients developing colorectal cancer. Ne...
详细信息
Oriented immobilization of enzymes helps to maintain their native structure and proper orientation for high-performance engineering to meet extensive biocatalysis ***,the supporting materials used for orientated immob...
详细信息
Oriented immobilization of enzymes helps to maintain their native structure and proper orientation for high-performance engineering to meet extensive biocatalysis ***,the supporting materials used for orientated immobilization are usually costly or complicated in preparation,affecting their practical *** this work,a facile purification and immobilization method was proposed for enzyme immobilization based on organic-inorganic hybrid calcium phosphate nanocrystal(Ca Ps)induced by Cu^(2+) modified bovine serum albumin(BSA-Cu).Then,the as-prepared hybrid calcium phosphate nanosheet,BSA-Cu@Ca Ps,was utilized for one-pot purification and immobilization of His-tagged organophosphorus hydrolase(OPH)by metal-affinity binding to the incorporated ***-Cu@Ca PsOPH exhibited enhanced p H stability and thermal stability compared to the free ***,BSA-Cu@Ca Ps-OPH could retain more than 75%and 56%of initial activity after reuse 5 and 10 times,*** results demonstrated that this facile strategy was promising for the effective biodegradation of organophosphorus pesticides with the immobilized enzyme.
In this study, we design a smart mask based on an ultrathin retractable flexible fiber optic sensor with high sensitivity(0.56 V/m-1), ultra-light mass(0.24 g), and excellent tensile properties. The sensor was integ...
详细信息
In this study, we design a smart mask based on an ultrathin retractable flexible fiber optic sensor with high sensitivity(0.56 V/m-1), ultra-light mass(0.24 g), and excellent tensile properties. The sensor was integrated with a medical mask to recognize multiple breathing patterns(standard, fast, slow, shallow, deep, breath-holding), coughing, and speaking,as well as to study gender characteristics and physiological differences in the respiratory system. By comparing the nasal-oral respiratory waveforms and frequencies, guidance for respiratory correction was provided. In addition, affixing flexible fiber optic sensors to the outside of the mask reduces the risk of cross-infection and significantly reduces temperature and humidity disturbances. Studies have shown that nine sensor locations placed on the outside of the mask responded significantly to respiratory waveforms. For personalized health management, the system is also equipped with a communication module,web and mobile apps to support data downloads, real-time monitoring, and exception alerts.
A microwave-induced thermoacoustic imaging(MITAT)system is a non-destructive physical medical imaging method that combines the advantages of the high contrast of microwave imaging and the high resolution of ultrasound...
详细信息
A microwave-induced thermoacoustic imaging(MITAT)system is a non-destructive physical medical imaging method that combines the advantages of the high contrast of microwave imaging and the high resolution of ultrasound *** uses the microwave as the excitation source and ultrasound as the information *** different kinds of biological tissue absorb electromagnetic energy,it results in localized temperature *** thermal expansion will induce ultrasonic signals(i.e.,thermoacoustic signals),known as the thermoacoustic *** microwave absorption image of the sample can be reconstructed by algorithm *** MITAT contrast depends on different dielectric parameters of different kinds of *** introduce the developed system and its *** addition,the challenges and prospects of MITAT for further development are discussed.
Deposition of β-amyloid protein(Aβ) is the main hallmark of Alzheimer's disease(AD), and it has been well recognized that Cu^(2+)-mediated Aβ aggregation plays a crucial role in AD pathological ***^(2+)binding ...
详细信息
Deposition of β-amyloid protein(Aβ) is the main hallmark of Alzheimer's disease(AD), and it has been well recognized that Cu^(2+)-mediated Aβ aggregation plays a crucial role in AD pathological ***^(2+)binding to Aβ can promote the production of reactive oxygen species(ROS) through Fenton-like reactions and produce more toxic Aβ-Cu^(2+)species under Cu^(2+)stimulation. Thus, the development of nanomaterials that can inhibit Cu^(2+)-mediated Aβ aggregation and degrade Aβ-Cu^(2+)complexes is considered an effective strategy for the prevention and treatment of AD. In this study, polydopamine nanoparticles(PDA NPs) were prepared and the results reveal that PDA NPs potently inhibit Cu^(2+)-mediated Aβaggregation and effectively reduce the formation of Aβ-Cu^(2+)complexes. In vitro experiments show that PDA NPs efficiently eliminate ROS generation catalyzed by Cu^(2+)or Aβ-Cu^(2+)complexes, thus rescuing cultured cells by reducing intracellular ROS levels. More importantly, PDA NPs can depolymerize Aβ-Cu^(2+)complexes, and the degradation of Aβ-Cu^(2+)complexes is promoted by near-infrared light irradiation due to their high photothermal conversion ability. In vivo studies reveal that PDA NPs significantly reduce the deposition of Aβ plaques in the presence of Cu^(2+)and extend the lifespan of AD nematodes from 11 to 14 d. Thus, the PDA NPs developed herein are multifunctional against Cu^(2+)-mediated Aβ aggregation for the potential prevention and treatment of AD.
暂无评论