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2020 International Conference on Nuclear Engineering, ICONE 2020, collocated with the ASME 2020 Power Conference

作者： Sun, Jianchuang Ding, Ming Mi, Zhengpeng Zhang, Zhuohua Fundamental Science on Nuclear Safety and Simulation Technology Laboratory Harbin Engineering University Harbin China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China Chengdu China

ISBN: (纸本)9780791883785

Direct contact condensation (DCC) is a common physical phenomenon appearing in the nuclear power plants and other industrial applications. The current research on DCC focuses on steam-water counterflow or jet flow under forced flow conditions. For some natural-circulation passive safety systems in floating nuclear power plants, the heated section is connected with the heat sink by the horizontal pipes. The heat sink is usually the ocean. In such natural circulation systems (NCSs), the steam produced in the heated section will inevitably contact the subcooled water in the ocean and result in DCC event. In this paper, the fundamental characteristics of two-phase flow were described in detail. In addition, the influences of the subcooled water temperature on the flow rate, outlet temperature, steam bubble behaviors, and pressure surge were emphatically discussed. The experimental results revealed that the subcooled water in the water tank could reversely flow into the pipe, which was able to cause condensation induced water hammer (CIWH) event and flow oscillation. Further research showed that the subcooled water was evidently prevented from reversely flowing into the pipe with the increase in the subcooled water temperature. The position where the DCC event occurs transferred from the pipe to the water tank, and the pressure peak obviously reduced, even disappear when the subcooled water temperature is larger than 61 oC. © 2020 American Society of Mechanical Engineers (ASME). All rights reserved.

关键词： Water temperature

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Enhanced optical imaging and fluorescent labeling for visualizing drug molecules within living organisms

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2428-2446页

作者： Ting Sun Huanxin Zhao Luyao Hu Xintian Shao Zhiyuan Lu Yuli Wang Peixue Ling Yubo Li Kewu Zeng Qixin Chen School of Pharmaceutical Sciences National Key Laboratory of Advanced Drug Delivery SystemMedical Science and Technology Innovation CenterShandong First Medical University&Shandong Academy of Medical SciencesJinan 250062China Departments of Diagnostic Radiology SurgeryChemical and Biomolecular Engineeringand Biomedical EngineeringYong Loo Lin School of Medicine and College of Design and EngineeringNational University of SingaporeSingapore 119074Singapore Institute of Biochemical and Biotechnological Drugs School of Pharmaceutical SciencesCheeloo College of MedicineShandong UniversityJinan 250012China Key Laboratory of Biopharmaceuticals Postdoctoral Scientific Research WorkstationShandong Academy of Pharmaceutical ScienceJinan 250098China State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China School of Life Sciences Science and Technology Innovation CenterShandong First Medical University&Shandong Academy of Medical SciencesJinan 250062China School of Chinese Materia Medica Tianjin University of Traditional Chinese MedicineTianjin 301617China Tianjin Pharmaceutical DA REN TANG Group Corporation Limited Traditional Chinese Pharmacy Research Institute Tianjin 300457China Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemistry Engineering and TechnologyTianjin UniversityTianjin 300072China

The visualization of drugs in living systems has become key techniques in modern *** advancements in optical imaging technologies and molecular design strategies have revolutionized drug *** the subcellular level,super-resolution microscopy has allowed exploration of the molecular landscape within individual cells and the cellular response to *** beyond subcellular imaging,researchers have integrated multiple modes,like optical near-infrared II imaging,to study the complex spatiotemporal interactions between drugs and their *** combining these visualization approaches,researchers gain supplementary information on physiological parameters,metabolic activity,and tissue composition,leading to a comprehensive understanding of drug *** review focuses on cutting-edge technologies in drug visualization,particularly fluorescence imaging,and the main types of fluorescent molecules ***,we discuss current challenges and prospects in targeted drug research,emphasizing the importance of multidisciplinary cooperation in advancing drug *** the integration of advanced imaging technology and molecular design,drug visualization has the potential to redefine our understanding of pharmacology,enabling the analysis of drug micro-dynamics in subcellular environments from new perspectives and deepening pharmacological research to the levels of the cell and organelles.

关键词： Optical imaging Drug visualization Fluorophore labeling Therapeutics

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GNN-Assisted BiG-AMP: Joint Channel Estimation and Data Detection for Massive MIMO Receiver

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IEEE Transactions on Wireless Communications 2025年

作者： Liu, Zishen Wu, Nan He, Dongxuan Yuan, Weijie Li, Yonghui Quek, Tony Q. S. School of Information and Electronics Beijing Institute of Technology Beijing100081 China School of System Design and Intelligent Manufacturing Shenzhen Key Laboratory of Robotics and Computer Vision Southern University of Science and Technology Shenzhen518055 China School of Electrical and Information Engineering The University of Sydney SydneyNSW2008 Australia Singapore University of Technology and Design 487372 Singapore Department of Electronic Engineering Kyung Hee University Yongin17104 Korea Republic of

In this paper, we develop a graph neural network (GNN)-assisted bilinear inference approach to enhance the receiver performance of the MIMO system through message passing-based joint channel estimation and data detection (JCD). Specifically, based on the bilinear generalized approximate message passing (BiG-AMP) framework and conditional correlation of signal, we propose a GNN-assisted BiG-AMP (GNN-BiGAMP) approach, which integrates a GNN module into the data-detection-loop to compensate the inaccurate marginal likelihood approximation. By leveraging the coupling between the channel and received symbols, a bilinear GNN-assisted BiG-AMP (BiGNN-BiGAMP) JCD receiver is further proposed. This method incorporates two GNNs with similar graph representation into the bilinear posterior estimation loops, which not only compensates for approximation errors but also alleviates performance loss due to premature variance convergence, thereby enhancing the receiver performance significantly. To fully exploit the supervised information from channel estimation and data detection, we propose a multitask learning based training scheme, which coordinates GNNs with different tasks in two loops. Simulation results show that our proposed GNN-assisted JCD receivers significantly outperform other JCD counterparts in terms of both channel estimation and data detection. © 2025 IEEE. All rights reserved.

关键词： Graph neural networks

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Preliminary experimental validation of multi-loop natural circulation model based on RELAP5/SCDAPSIM/MOD 4.0

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International Journal of Advanced Nuclear reactor design and technology 2020年 2卷 25-33页

作者： Zahraddeen, Abbati Chen, Jiarui Cheng, Kun Zhao, Fulong Tan, Sichao Fundamental Science on Nuclear Safety and Simulation Technology Laboratory Harbin Engineering University Harbin 150001 China Abuja Nigeria Science and Technology on Reactor Design Technology Nuclear Power Institute of China Chengdu610213 China

Passive safety systems mostly working on the principles of natural circulation are given much priority in increasing the reliability of reactors’ inherent safety features. In view of this, many researchers carry out numerical and experimental studies in single-loop natural circulation model to study the natural circulation behaviors. In the present study, the experimental loop consists of three loops;two of which operate on natural circulation while the third on forced circulation. The experimental loop has successfully established natural circulation under different pressure conditions and the experimental results obtained are compared with those of the RELAP5 code simulation for validating the multi-loop natural circulation RELAP5 model. Single-phase natural circulation flow rates and temperatures at various locations give reasonable agreements between the code and the experiment. The results show that height difference between the heat source and the heat sink is more influential than system pressure in increasing natural circulation flow rate. The system pressure maintains the stability of the system, thus keeping it within single-phase region with increase in heat. In addition, temperature difference in the first loop being higher than that of the second loop at all pressures, did not influence the first loop flow rate to be higher due to the advantage of height difference in the second loop. However, extending the conditions beyond those of the experiment, that is higher power and system pressure, the first loop flow rate increased more than that of the second loop as predicted by the RELAP5 code. © 2020

关键词： Flow rate

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From laboratory to on-site operation:Reevaluation of empirically based electric water chiller models

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Building Simulation 2022年第2期15卷 213-232页

作者： Bin Zhang Shijun You Sheng Wang Xiaoxiao Ding Chuang Wang Yan Gao School of Environmental Science and Engineering Tianjin UniversityTianjin 300072China State Key Laboratory of Air-Conditioning Equipment and System Energy Conservation Zhuhai 519070China Guangdong Key Laboratory of Refrigeration Equipment and Energy Conservation Technology Zhuhai 519070China Beijing Key Laboratory of Heating Gas SupplyVentilating and Air Conditioning EngineeringBeijing University of Civil Engineering and ArchitectureBeijing 100044China Beijing Advanced Innovation Center for Future Urban Design Beijing University of Civil Engineering and ArchitectureBeijing 100044China

Chiller model is a key factor to building energy simulation and chiller performance *** spread of new types of electric water chillers that have higher performance and wider operating range,new challenges have been faced by building energy simulation tools and their chiller *** work takes a new type of electric water chiller as a case study and reevaluates eight typical empirically based models for predicting the energy performance of electric water chiller to verify whether they are suitable for the new type of chiller,using both laboratory test data from chiller manufacturer and online monitoring data from on-site operation of a central cooling plant with chillers of the same *** prediction ability of the chiller models(including model prediction accuracy and generation ability)in laboratory test and on-site operation situations are *** results show that the existing models can well describe the chiller performance in the laboratory test situation but perform poorly in the on-site operation *** the best two models in the laboratory dataset,the overall prediction errors of DOE-2 and GN model increase more than 250%and 75%respectively in the field *** big discrepancy of model prediction accuracy in the two situations is mainly due to the differences of evaporator and condenser water flow rates between the laboratory and on-site operation datasets,which indicates the limitations of the empirical chiller models and implies further research in future in order to improve the suitability and reliability of chiller model.

关键词： electric water chiller performance model model validation model prediction ability variable water flow rates

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Study on irradiation damage of rpv steels based on coupling cluster dynamics and crystal plasticity finite element method

Study on irradiation damage of rpv steels based on coupling ...

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2020 International Conference on Nuclear Engineering, ICONE 2020, collocated with the ASME 2020 Power Conference

作者： Wang, Xiaotong Luo, Ying Dong, Yuanyuan Yao, Weihua Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China Chengdu China Nuclear Power Institute of China Chengdu China

ISBN: (纸本)9780791883785

Irradiation hardening is one of the most important aging effects of reactor pressure vessel (RPV) steel in long-term service. A number of studies have indicated that irradiation hardening is mainly caused by irradiation induced defects, such as dislocation loops and precipitates. In this paper, we have simulated the irradiation damage of low-copper reactor pressure vessel (RPV) steel. The generation of Mn-Ni-Si precipitates is simulated by the cluster dynamics model based on rate theory. On this basis, the crystal plasticity finite element method based on modified crystal plasticity model is used to simulate the effect of Mn-Ni-Si precipitates on the mechanical properties of RPV steels. The simulated results has been compared with the experimental results from the literature. By coupling the cluster dynamics and the crystal plastic finite element method, we suggest a multi-scale simulation method to simulate and predict irradiation damage of RPV steel. © 2020 American Society of Mechanical Engineers (ASME). All rights reserved.

关键词： Finite element method

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An Ontology-based Knowledge Modeling towards Eco-design for Additive Manufacturing 31

An Ontology-based Knowledge Modeling towards Eco-Design for ...

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31st CIRP Conference on Life Cycle Engineering, LCE 2024

作者： Wang, Yanan Peng, Tao Kim, Samyeon Xiong, Yi Tang, Yunlong Tang, Renzhong State Laboratory of Fluid Power Components and Mechatronic Systems School of Mechanical Engineering Zhejiang University Hangzhou310058 China Department of Mechanical Engineering Jeonju University Jeonju-si Jeollabuk-do55069 Korea Republic of School of System Design and Intelligent Manufacturing Southern University of Science and Technology Shenzhen518055 China Mechanical and Aerospace Engineering Department Monash University Melbourne3800 Australia Materials Science and Engineering Department Monash University Melbourne3800 Australia Zhejiang Province Key Laboratory of Advanced Manufacturing Technology School of Mechanical Engineering Zhejiang University Hangzhou310058 China

Owing to the unique technological merits of additive manufacturing (AM), design for AM, particularly eco-design for AM, has been gaining attention in improving the sustainable performance of AM-fabricated (AMed) parts. The main challenge in harvesting potential sustainability benefits is how to capture the impact of design on sustainable performance. Though several existing studies adopted quantitative evaluation on AM sustainability and investigated the relationships between design information and sustainability information of AMed part, the sustainability information is still unavailable in the design phase. This hardly guides eco-design for AM in practice. To support the increasing industrial applications of AM, this paper illustrates related knowledge, that is, material-process-structure-ecoProperty (MPSeP) relationships to connect design and sustainability information in eco-design for AM. An ontology-based method is proposed to model the MPSeP relationships of the AMed part in a structured way. An example of an AMed hydraulic valve body was used to demonstrate the MPSeP modeling process. It is discussed that how the constructed model effectively assists AM designers through providing eco-design recommendation, and enables design software tools to perform sustainability analysis towards eco-design for AM. © 2024 The Author(s).

关键词： 3D printing

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Burnup performance analysis for candidate materials of the LWR accident tolerant control rod 14

Burnup performance analysis for candidate materials of the L...

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14th International Nuclear Fuel Cycle Conference, GLOBAL 2019 and Light Water reactor Fuel Performance Conference, TOP FUEL 2019

作者： Liu, Yong Li, Mancang Yu, Yingrui Xiao, Peng Wang, Xingbo Zhang, Bin Wang, Dongyong Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China 328# Section 1 Changshun Avenue Chengdu China

The accident tolerant fuel (ATF) is considered to be one of the most advanced concepts to improve the safety of light water reactors (LWRs). The accident tolerant control rod (ATCR) is a significant aspect in the ATF concept. The melting temperature of traditional LWR control rod (CR) materials, such as silver-indium-cadmium (AIC) alloy, is too low to endure the high temperature under several accident conditions. Consequently, varieties of candidate materials for control rod have been proposed in the previous researches because of the outstanding characters of high-temperature behavior, as well as reactivity worth, stability in coolant water and so on. In this paper, the burnup performance of the sesquioxides of the rare-earth elements (RE2O3) and the hafnia (Hf) are analyzed and compared to the traditional AIC control rod. Two parameters are chosen to reveal the burnup performance of the candidate control rod materials, the initial control rod reactivity worth and the stability of the control rod reactivity worth along with the assembly burnup. The candidate-material control rods and the AIC control rod are placed in the ATF assembly with the same conditions, and the assembly is depleted to sufficient burnup. Numerical results indicate that Eu2O3, Dy2O3, Sm2O3 and Hf are excellent ATCR materials compared to AIC. The initial control rod reactivity worth of these materials is not less than that of AIC, and the burnup stability is outstanding, especially Eu2O3 and Dy2O3 Copyright © GLOBAL 2019 - International Nuclear Fuel Cycle Conference and TOP FUEL 2019 - Light Water reactor Fuel Performance *** rights reserved.

关键词： Hafnium oxides

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Super-Twisting Control for Re-entry Rigid-Elastic Coupled Hypersonic Vehicles

Super-Twisting Control for Re-entry Rigid-Elastic Coupled Hy...

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Chinese Automation Congress (CAC)

作者： Wentao Tang Junfang Fan Yi Ji Yafeng Li Xiaobin Xu Luyao Zang Beijing Key Laboratory of High Dynamic Navigation Technology Beijing Information Science and Technology University Beijing China School of Automation Beijing Information Science and Technology University Beijing China The System Design Institute of Mechan-ical-Electrical Engineering Beijing China

A super-twisting control strategy is proposed to tackle the complex problem of attitude stabilization control for rigid-elastic coupled hypersonic vehicles experiencing significant aerodynamic perturbations. Initially, the elastic modes are treated as uncertain factors, leading to the construction of a control-oriented dynamic model. To design the attitude subsystem, a combination of a super-twisting algorithm and a non-singular terminal sliding mode is proposed. A first-order differentiator is introduced to address the “derivative explosion” issue commonly found in traditional control methods, thus eliminating the need for intricate differential computations. Moreover, a switching control strategy is integrated into the nonlinear feedback control law design, ensuring robust velocity tracking. Simulation results validate that the proposed control method surpasses conventional methods in both tracking performance and robustness.

关键词：

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DC-Side Decoupling Method of DC-link Capacitor Reduction for Single Phase PWM Rectifier

DC-Side Decoupling Method of DC-link Capacitor Reduction for...

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2020 IEEE Sustainable Power and Energy Conference, iSPEC 2020

作者： Wang, Jinxin Renyong, Peng Dai, Kailei Zhang, Zhiqiang Zhang, Ting Zhao, Junjie Chen, Qian Zhang, Jianjian Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of China Chengdu China Nuclear Power Institute of China Chengdu China

ISBN: (纸本)9781728191645

The integrated charging system of Electric vehicle consists of a single-phase PWM rectifier and a Buck converter. When the single-phase PWM rectifier works with unit power factor, the dc-link voltage contains a large voltage harmonic of twice the grid frequency. Although the output voltage ripple can be controlled within the required range using the proper control of the Buck converter, the second-order harmonic on the dc-link capacitor is inevitable. This paper proposes a de-side decoupling method for the second-order harmonic problem of the dc-link voltage of the integrated charging system. A de-side decoupling half bridge is connected in parallel to absorb the ripple power of twice the grid frequency. This paper analyzes the operating principle of the de-side decoupling half bridge. Based on a theoretical analysis of the topology and the design procedure for controlling system, the proposed converter is designed and simulated. Finally, simulation results are given to verify the method. © 2020 IEEE.

关键词： Pulse width modulation

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