检索结果-内蒙古大学图书馆

38th International Cosmic Ray Conference, ICRC 2023

作者： Cannady, Nicholas Adriani, O. Akaike, Y. Asano, K. Asaoka, Y. Berti, E. Bigongiari, G. Binns, W.R. Bongi, M. Brogi, P. Bruno, A. Cannady, N. Castellini, G. Checchia, C. Cherry, M.L. Collazuol, G. de Nolfo, G.A. Ebisawa, K. Ficklin, A.W. Fuke, H. Gonzi, S. Guzik, T.G. Hams, T. Hibino, K. Ichimura, M. Ioka, K. Ishizaki, W. Israel, M.H. Kasahara, K. Kataoka, J. Kataoka, R. Katayose, Y. Kato, C. Kawanaka, N. Kawakubo, Y. Kobayashi, K. Kohri, K. Krawczynski, H.S. Krizmanic, J.F. Maestro, P. Marrocchesi, P.S. Messineo, A.M. Mitchell, J.W. Miyake, S. Moiseev, A.A. Mori, M. Mori, N. Motz, H.M. Munakata, K. Nakahira, S. Nishimura, J. Okuno, S. Ormes, J.F. Ozawa, S. Pacini, L. Papini, P. Rauch, B.F. Ricciarini, S.B. Sakai, K. Sakamoto, T. Sasaki, M. Shimizu, Y. Shiomi, A. Spillantini, P. Stolzi, F. Sugita, S. Sulaj, A. Takita, M. Tamura, T. Terasawa, T. Torii, S. Tsunesada, Y. Uchihori, Y. Vannuccini, E. Wefel, J.P. Yamaoka, K. Yanagita, S. Yoshida, A. Yoshida, K. Zober, W.V. Department of Physics University of Florence Via Sansone 1 Sesto Fiorentino50019 Italy INFN Sezione di Firenze Via Sansone 1 Sesto Fiorentino50019 Italy Waseda Research Institute for Science and Engineering Waseda University 17 Kikuicho Shinjuku Tokyo162-0044 Japan JEM Utilization Center Human Spaceflight Technology Directorate Japan Aerospace Exploration Agency 2-1-1 Sengen Ibaraki Tsukuba305-8505 Japan Institute for Cosmic Ray Research The University of Tokyo 5-1-5 Kashiwa-no-Ha Chiba Kashiwa277-8582 Japan Via Madonna del Piano 10 Sesto Fiorentino50019 Italy Department of Physical Sciences Earth and Environment University of Siena via Roma 56 Siena53100 Italy INFN Sezione di Pisa Polo Fibonacci Largo B. Pontecorvo 3 Pisa56127 Italy Department of Physics McDonnell Center for the Space Sciences Washington University One Brookings Drive St. LouisMO63130-4899 United States Heliospheric Physics Laboratory NASA GSFC GreenbeltMD20771 United States Center for Space Sciences and Technology University of Maryland Baltimore County 1000 Hilltop Circle BaltimoreMD21250 United States Astroparticle Physics Laboratory NASA/GSFC GreenbeltMD20771 United States Center for Research and Exploration in Space Sciences and Technology NASA GSFC GreenbeltMD20771 United States Department of Physics and Astronomy Louisiana State University 202 Nicholson Hall Baton RougeLA70803 United States Department of Physics and Astronomy University of Padova Via Marzolo 8 Padova35131 Italy INFN Sezione di Padova Via Marzolo 8 Padova35131 Italy Institute of Space and Astronautical Science Japan Aerospace Exploration Agency 3-1-1 Yoshinodai Chuo Kanagawa Sagamihara252-5210 Japan Kanagawa University 3-27-1 Rokkakubashi Kanagawa Kanagawa Yokohama221-8686 Japan Faculty of Science and Technology Graduate School of Science and Technology Hirosaki University 3 Bunkyo Hirosaki Aomori036-8561 Japan Yukawa Institute for Theoretical Physics Kyoto

The Calorimetric Electron Telescope (CALET) is a deep electromagnetic calorimeter designed for the measurement of cosmic-ray electrons on the International space Station. Deployed on the Exposed Facility of the Japanese Experiment Module since August 2015, it observes cosmic-ray electrons with energies up to above 10 TeV and hadrons up to PeV total energies. It is also sensitive to gamma rays in the energy range from 1 GeV to 1 TeV. At energies above 100 GeV, sensitivity is lost in the gamma-ray selection as previously defined. This is due in large part to the contamination of the charge measurement in the CHD (Charge Detector) and the IMC (Imaging Calorimeter) by backscattered particles from the electromagnetic shower in the TASC (Total Absorption Calorimeter). In this work, we implement a revision to the photon selection criteria using a significantly increased simulated dataset, increasing CALET’s exposure at these energies significantly. Furthermore, the allowable geometry for incident photons is expanded and the energy reconstruction revised to tighten the energy resolution for highly inclined tracks. We validate the distributions used for the selection through comparison with real data, evaluate the changes to the instrument response functions, and assess the implications for the flight data analysis of gamma rays with CALET. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Cosmology

来源：评论

学校读者我要写书评

暂无评论

Flux ratios of primary elements measured by CALET on the International space Station 38

Flux ratios of primary elements measured by CALET on the Int...

引用

38th International Cosmic Ray Conference, ICRC 2023

作者： Checchia, Caterina Stolzi, Francesco Adriani, O. Akaike, Y. Asano, K. Asaoka, Y. Berti, E. Bigongiari, G. Binns, W.R. Bongi, M. Brogi, P. Bruno, A. Cannady, N. Castellini, G. Checchia, C. Cherry, M.L. Collazuol, G. de Nolfo, G.A. Ebisawa, K. Ficklin, A.W. Fuke, H. Gonzi, S. Guzik, T.G. Hams, T. Hibino, K. Ichimura, M. Ioka, K. Ishizaki, W. Israel, M.H. Kasahara, K. Kataoka, J. Kataoka, R. Katayose, Y. Kato, C. Kawanaka, N. Kawakubo, Y. Kobayashi, K. Kohri, K. Krawczynski, H.S. Krizmanic, J.F. Maestro, P. Marrocchesi, P.S. Messineo, A.M. Mitchell, J.W. Miyake, S. Moiseev, A.A. Mori, M. Mori, N. Motz, H.M. Munakata, K. Nakahira, S. Nishimura, J. Okuno, S. Ormes, J.F. Ozawa, S. Pacini, L. Papini, P. Rauch, B.F. Ricciarini, S.B. Sakai, K. Sakamoto, T. Sasaki, M. Shimizu, Y. Shiomi, A. Spillantini, P. Stolzi, F. Sugita, S. Sulaj, A. Takita, M. Tamura, T. Terasawa, T. Torii, S. Tsunesada, Y. Uchihori, Y. Vannuccini, E. Wefel, J.P. Yamaoka, K. Yanagita, S. Yoshida, A. Yoshida, K. Zober, W.V. Department of Physical Sciences Earth and Environment University of Siena via Roma 56 Siena53100 Italy INFN Sezione di Pisa Polo Fibonacci Largo B. Pontecorvo 3 Pisa56127 Italy Department of Physics University of Florence Via Sansone 1 Sesto Fiorentino50019 Italy INFN Sezione di Firenze Via Sansone 1 Sesto Fiorentino50019 Italy Waseda Research Institute for Science and Engineering Waseda University 17 Kikuicho Shinjuku Tokyo162-0044 Japan JEM Utilization Center Human Spaceflight Technology Directorate Japan Aerospace Exploration Agency 2-1-1 Sengen Ibaraki Tsukuba305-8505 Japan Institute for Cosmic Ray Research The University of Tokyo 5-1-5 Kashiwa-no-Ha Kashiwa Chiba277-8582 Japan Via Madonna del Piano 10 Sesto Fiorentino50019 Italy Department of Physics McDonnell Center for the Space Sciences Washington University One Brookings Drive St. LouisMO63130-4899 United States Heliospheric Physics Laboratory NASA GSFC GreenbeltMD20771 United States Center for Space Sciences and Technology University of Maryland Baltimore County 1000 Hilltop Circle BaltimoreMD21250 United States Astroparticle Physics Laboratory NASA GSFC GreenbeltMD20771 United States Center for Research and Exploration in Space Sciences and Technology NASA GSFC GreenbeltMD20771 United States Department of Physics and Astronomy Louisiana State University 202 Nicholson Hall Baton RougeLA70803 United States Department of Physics and Astronomy University of Padova Via Marzolo 8 Padova35131 Italy INFN Sezione di Padova Via Marzolo 8 Padova35131 Italy Institute of Space and Astronautical Science Japan Aerospace Exploration Agency 3-1-1 Yoshinodai Chuo Kanagawa Sagamihara252-5210 Japan Kanagawa University 3-27-1 Rokkakubashi Kanagawa Kanagawa Yokohama221-8686 Japan Faculty of Science and Technology Graduate School of Science and Technology Hirosaki University 3 Bunkyo Hirosaki Aomori036-8561 Japan Yukawa Institute for Theoretical Physics Kyot

The study of flux ratios of cosmic-ray primary elements is of particular interest not only to assess the relative abundance of each element, but also to gain a deeper understanding of their propagation in the galaxy. High energy cosmic ray data are the best candidate for this purpose as convection, nuclear decay, and energy degradation can be neglected during their propagation. CALET on the International space Station has been measuring the flux of several primary elements from proton to nickel for 7 years to date. In this contribution, the flux ratios of heavy primary elements to lighter primaries will be shown, extending the energy range already investigated by previous measurements. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Cosmology

来源：评论

学校读者我要写书评

暂无评论

Anthropogenic emission is the main contributor to the rise of atmospheric methane during 1993-2017

引用

National science Review 2022年第5期9卷 154-166页

作者：张臻 Benjamin Poulter Sara Knox Ann Stavert Gavin McNicol Etienne Fluet-Chouinard Aryeh Feinberg 赵园红 Philippe Bousquet Josep G.Canadell Anita Ganesan Gustaf Hugelius George Hurtt Robert B.Jackson Prabir K.Patra Marielle Saunois Lena H?glund-Isaksson 黄春林 Abhishek Chatterjee 李新 Department of Geographical Sciences University of Maryland Biospheric Sciences Laboratory NASA Goddard Space Flight Center Department of Geography University of British Columbia Global Carbon Project CSIRO Oceans and Atmosphere Department of Earth and Environmental Sciences University of Illinois Chicago Department of Earth System Science Stanford University Institute for Data Systems and Society Massachusetts Institute of Technology College of Oceanic and Atmospheric Sciences Ocean University of China Laboratoire des Sciences du Climat et de l’Environment LSCE-IPSL (CEA-CNRS-UVSQ)Université Paris-Saclay School of Geographical Sciences University of Bristol Department of Physical Geography and Bolin Centre for Climate Research Stockholm University Woods Institute for the Environment and Precourt Institute for Energy Stanford University Research Institute for Global Change JAMSTEC International Institute for Applied Systems Analysis (IIASA) Northwest Institute of Eco-Environment and Resources Chinese Academy of Sciences Global Modeling and Assimilation Office NASA Goddard Space Flight Center Universities Space Research Association Institute of Tibetan Plateau Research Chinese Academy of Sciences

Atmospheric methane（CH4） concentrations have shown a puzzling resumption in growth since 2007 following a period of stabilization from 2000 to *** hypotheses have been proposed to explain the temporal variations in CH4growth,and attribute the rise of atmospheric CH4either to increases in emissions from fossil fuel activities,agriculture and natural wetlands,or to a decrease in the atmospheric chemical ***,we use a comprehensive ensemble of CH4source estimates and isotopic δ13C-CH4source signature data to show that the resumption of CH4growth is most likely due to increased anthropogenic *** emission scenarios that have the fewest biases with respect to isotopic composition suggest that the agriculture,landfill and waste sectors were responsible for 53±13% of the renewed growth over the period 2007-2017 compared to 2000-2006;industrial fossil fuel sources explained an additional 34 ±24%,and wetland sources contributed the least at 13 ±9%.The hypothesis that a large increase in emissions from natural wetlands drove the decrease in atmospheric δ13C-CH4values cannot be reconciled with current process-based wetland *** finding suggests the need for increased wetland measurements to better understand the contemporary and future role of wetlands in the rise of atmospheric methane and climate *** findings highlight the predominant role of anthropogenic activities in driving the growth of atmospheric CH4concentrations.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Mid-Infrared Deep Subwavelength Confinement in Graphene Plasmonic Waveguides

SSRN

引用

SSRN 2023年

作者： Qin, Yimian Ma, Cunbao Lian, Yu Huang, Lihao Yuan, Yufeng Sha, Minggong Ye, Xinli Zheng, Kai School of Civil Aviation Northwestern Polytechnical University Xi’an710072 China China Academy of Space Technology Beijing City100094 China China Aerospace Science and Technology Corporation Beijing100094 China School of Electronic Engineering and Intelligentization Dongguan University of Technology Dongguan523808 China Yangtze River Delta Research Institute of Northwestern Polytechnical University Suzhou215400 China Research & Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen518057 China The Center for Biomedical Optics and Photonics College of Physics and Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems Shenzhen University Shenzhen518060 China

Strong optical field intensity is greatly desired in mid-infrared (MIR) photonics to confine light on miniaturized compact-size chips. However, due to a fundamental trade-off between energy confinement and propagation loss, it has been a challenging task to obtain further deep subwavelength confinement. In this study, we present a simple graphene waveguide that generates image plasmons assisted by metallic cylindrical nanowires operating at a wavelength of 15 µm. Due to high-mobility graphene encapsulated by hexagonal boron nitride (hBN) and ultra-confined image plasmonic mode, the resulting waveguide has two orders of magnitude smaller mode area than the strongest confinement waveguides to date, in conjunction with comparable loss. Furthermore, by the tunable graphene locations in the gap, we implement an efficient manipulation of the mode area across an order of magnitude. Such high-performance waveguides may be exploited for deep subwavelength field-enhanced devices, which promise to be unprecedented pathways for nanoscale transmission and manipulation of MIR light. © 2023, The Authors. All rights reserved.

关键词： Graphene

来源：评论

学校读者我要写书评

暂无评论

Aquatic Ecosystems science Using an Imaging Spectrometer 26

Aquatic Ecosystems Science Using an Imaging Spectrometer

引用

Imaging Spectrometry XXVI: Applications, Sensors, and Processing 2023

作者： Lockwood, Ronald Bachmann, Charles M. Chrisp, Michael Smeaton, Corrie Pahlaven, Nima Hochberg, Eric Montes, Marcos J. Gao, Bo-Cai Frouin, Robert Vodacek, Anthony Fichot, Cedric Bell, Tom W. Armstrong, Roy A. Li, Chunyan Kennedy, Laura Gillmer, Steve Fuhrman, Linda Brouhard, Derrick Wang, Jade Thome, Kurtis MIT Lincoln Laboratory 244 Woods Street LexingtonMA United States Rochester Institute of Technology Chester F. Carlson Center for Imaging Science RochesterNY United States Science Systems and Applications NASA Goddard Space Flight Center 8800 Greenbelt Road GreenbeltMD United States Bermuda Institute of Ocean Sciences 17 Biological Station St. George'sGE01 Bermuda Remote Sensing Division Naval Research Laboratory Code 7231 4555 Overlook Avenue SW WashingtonDC United States Scripps Institution of Oceanography University of California 9500 Gilman Drive La Jolla San DiegoCA United States Department of Earth and Environment Boston University 685 Commonwealth Ave BostonMA United States Woods Hole Oceanographic Institution 266 Woods Hole Road Woods HoleMA United States Department of Marine Sciences University of Puerto Rico Mayaguez P.O. Box 9000 Mayaguez Puerto Rico Department of Oceanography and Coastal Sciences Louisiana State University 1002-Y Energy Coast & Environment Building Baton RougeLA United States NASA Goddard Space Flight Center 8800 Greenbelt Road GreenbeltMD United States

ISBN: (纸本)9781510665903

The study of aquatic ecosystems is an important research area addressing diverse problems such as carbon sequestration in coastal margins and wetlands, kelp and seagrass studies, coral reefs, harmful algal blooms and hypoxia, and carbon cycling in this dynamic environment. The application of an imaging spectrometer to aquatic ecosystem study is particularly challenging due to low water-leaving radiance levels adjacent to the shore region with its higher values. The Committee on Earth Observation Satellites (CEOS) has established more stringent performance standards for the visible/near infrared wavelengths than are typically available in imaging spectrometer designs. We have recently developed a compact form imaging spectrometer, the Chrisp Compact VNIR/SWIR Imaging Spectrometer (CCVIS), that facilitates their modular usage with a wide field telescope without sacrificing performance. The CCVIS design and the operational concept have predicted performance that approaches the CEOS standards. The envisioned satellite implementation requires a pitchback maneuver where the imaging of the slit projected onto the surface is slowly scanned while recording focal plane array readouts at a higher rate thereby avoiding saturation over the land surface while obtaining a high signal-to-noise ratio over the water. The effective frame rate is determined by the time it takes to scan the projected slit one ground sample distance (GSD). This approach has the added benefit of measuring a range of angles during a single GSD acquisition, providing insight into the bidirectional reflectance distribution function (BRDF). © 2023 SPIE.

关键词： Hyperspectral imaging

来源：评论

学校读者我要写书评

暂无评论

Multi-Domain Virtual Network Embedding Algorithm based on Horizontal Federated Learning

arXiv

引用

arXiv 2022年

作者： Zhang, Peiying Chen, Ning Li, Shibao Choo, Kim-Kwang Raymond Jiang, Chunxiao Qingdao266580 China The State Key Laboratory of Integrated Services Networks Xidian University Xi'An710071 China The Department of Information Systems and Cyber Security University of Texas at San Antonio San AntonioTX78249-0631 United States The National Research Center for Information Science and Technology Tsinghua University The Tsinghua Space Center Beijing100084 China

Network Virtualization (NV) is an emerging network dynamic planning technique to overcome network rigidity. As its necessary challenge, Virtual Network Embedding (VNE) enhances the scalability and flexibility of the network by decoupling the resources and services of the underlying physical network. For the future multi-domain physical network modeling with the characteristics of dynamics, heterogeneity, privacy, and real-time, the existing related works perform unsatisfactorily. Federated learning (FL) jointly optimizes the network by sharing parameters among multiple parties and is widely employed in disputes over data privacy and data silos. Aiming at the NV challenge of multi-domain physical networks, this work is the first to propose using FL to model VNE, and presents a VNE architecture based on Horizontal Federated Learning (HFL) (HFL-VNE). Specifically, combined with the distributed training paradigm of FL, we deploy local servers in each physical domain, which can effectively focus on local features and reduce resource fragmentation. A global server is deployed to aggregate and share training parameters, which enhances local data privacy and significantly improves learning efficiency. Furthermore, we deploy the Deep Reinforcement Learning (DRL) model in each server to dynamically adjust and optimize the resource allocation of the multi-domain physical network. In DRL-assisted FL, HFL-VNE jointly optimizes decision-making through specific local and federated reward mechanisms and loss functions. Finally, the superiority of HFL-VNE is proved by combining simulation experiments and comparing it with related works. Copyright © 2022, The Authors. All rights reserved.

关键词： Deep learning

来源：评论

学校读者我要写书评

暂无评论

νspaceSim: A Comprehensive simulation Package to Model the Optical and Radio Signals from Extensive Air Showers Induced by Cosmic Neutrinos and Measured by space-based Experiments 38

νSpaceSim: A Comprehensive Simulation Package to Model the ...

引用

38th International Cosmic Ray Conference, ICRC 2023

作者： Krizmanic, John F. Krizmanic, John Akaike, Yosui Anchordoqui, Luis Bergman, Douglas Buckland, Isaac Caraca-Valente, Jorge Cummings, Austin Eser, Johannes Garcia, Fred Angelo Batan Garg, Diksha Guépin, Claire Heibges, Tobias Ludwig, Andrew Mackovjak, Simon Mayotte, Eric Mayotte, Sonja Olinto, Angela Paul, Thomas Reustle, Alex Romero-Wolf, Andrew Reno, Mary Hall Sarazin, Fred Venters, Tonia Wiencke, Lawrence Wissel, Stephanie NASA GSFC Laboratory for Astroparticle Physics 8800 Grenbelt Rd GreenbeltMD20771 United States NASA Goddard Space Flight Center GreenbeltMD20771 United States Waseda Institute for Science and Engineering Waseda University Shinjuku Tokyo Japan Department of Physics and Astronomy Lehman College City University of New York New YorkNY10468 United States Department of Physics and Astronomy University of Utah Salt Lake CityUT84112 United States Department of Physics Colorado School of Mines GoldenCO80401 United States Department of Physics Pennsylvania State University State CollegePA16801 United States Department of Astronomy Astrophysics University of Chicago ChicagoIL60637 United States Department of Astronomy University of Maryland College Park College ParkMD20742 United States Université Montpellier Cedex 5 Montpellier France Jet Propulsion Laboratory California Institute of Technology PasadenaCA91109 United States Institute of Experimental Physics Slovak Academy of Sciences Kosice Slovakia ADNET Systems

νspaceSim is a comprehensive end-to-end simulation package created to facilitate the design of space-based and suborbital cosmic neutrino experiments that use the Earth as a neutrino converter as well as to understand the data obtained from current experiments. νspaceSim models all aspects of the processes that lead to the neutrino-induced extensive air shower (EAS) signals: the modeling of neutrino interactions inside the Earth, propagating the leptons through the Earth into the atmosphere, modeling the tau-lepton decays, forming composite EAS, generating the air optical Cherenkov and radio signals, modeling their propagation and attenuation through the atmosphere. Finally, the response of optical and radio detectors is modeled. νspaceSim uses a vectorized Python implementation to efficiently simulate neutrino-induced and background signals at a specific orbit or balloon altitude based on user xml input. The development has been focused on modeling the upward-moving EASs generated from Earth-emergent leptons sourced by neutrino interactions within the Earth, for both diffuse and transient sources accounting for the user-defined acceptance of an instrument. The tau-lepton channel is implemented using the modeling packages nuPyProp and nuLeptonSim. A MERRA-2 database driven application is used to generate cloud maps. Ionosphere dispersion of the radio signals is also modeled. In this paper, the νspaceSim software, physics modeling, and the cosmic neutrino measurement capabilities of example experimental configurations will be presented. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Cosmology

来源：评论

学校读者我要写书评

暂无评论

Rydberg electromagnetically induced transparency and absorption of strontium triplet states in a weak microwave field

arXiv

引用

arXiv 2022年

作者： Zhou, Yan-Li Yan, Dong Li, Weibin Department of Physics College of Liberal Arts and Sciences Interdisciplinary Center for Quantum Information National University of Defense Technology Changsha410073 China School of Science Key Laboratory of Materials Design and Quantum Simulation Changchun University Changchun130022 China School of Physics and Astronomy Centre for the Mathematics and Theoretical Physics of Quantum Non-Equilibrium Systems University of Nottingham NottinghamNG7 2RD United Kingdom

We study theoretically laser excitation of Rydberg triplet states of strontium atoms in the presence of weak microwave (MW) fields. Starting from the ground state 5s2 1S0, the Rydberg excitation is realized through the metastable, triplet 5s5p 3P1 state, whose decay rate γ2 is 2π × 7.5 kHz, much smaller than the one in the singlet state or alkali atoms. The influences of γ2 on the transparency and absorption spectrum in the electromagnetically induced transparency (EIT), and electromagnetically induced absorption (EIA) regime are examined. Narrow transparent windows (EIT) or absorption peaks (EIA) are found, whose distance in the spectrum depends on the Rabi frequency of the weak MW field. It is found that the spectrum exhibits higher contrast than using the singlet state or alkali atoms in typical situations. Using the metastable intermediate state, we find that resonance fluorescence of Sr gases exhibits very narrow peaks, which are modulated by the MW field. When the MW field is weaker than the probe and control light, the spectrum distance of these peaks are linearly proportional to Ωm. This allows us to propose a new way to sense very weak MW fields through resonance fluorescence. Our study shows that the Sr triplet state could be used to develop the Rydberg MW electrometry that gains unique advantages. Copyright © 2022, The Authors. All rights reserved.

关键词： Laser excitation

来源：评论

学校读者我要写书评

暂无评论

San-Huang-San reduces the effects of enteritis infection caused by Aeromonas sobria in common carp by modulating oxidative stress and the inflammatory response

引用

Aquaculture 2025年 608卷

作者： Huawei Feng Yuying Zhang Shan Zhao Yongzhen Wang Yu Hu Sai Zhang Xiang Qi Sixu Luo Jian Zhao Xiangming Ma Hui Zhang Li Zhang Zhikui Liu Hongsheng Liu School of Pharmaceutical Sciences Liaoning University Shenyang 110036 China Key Laboratory of Computational Simulation and Information Processing of Biomacromolecules of Liaoning Province Shenyang 110036 China Engineering Laboratory for Molecular Simulation and Designing of Drug Molecules of Liaoning Shenyang 110036 China Key Laboratory for Computer Simulating and Information Processing of Bio-macromolecules of Shenyang Shenyang 110036 China School of Life Science Liaoning University Shenyang 110036 China School of Mathematics and Systems Science Shenyang Normal University 110034 China Liaoning Huikang Testing and Evaluation Technology Co. Shenyang 110179 China

This study aimed to investigate the antioxidant and anti-inflammatory mechanisms of the traditional Chinese medicine compound San-Huang-San (SHS) on common carp infected with Aeromonas sobria . In this study, 22 major compounds in SHS were first detected using the UPLC–MS/MS method. Feeding experiments showed that SHS enhanced the intestinal barrier function, restoring the villus length and the number of inflammatory cells in infected fish to levels equivalent to those in the control. SHS significantly increased the abundance of the beneficial bacteria Cetobacterium , thereby improving the intestinal barrier. Compared with the INF group, the SHS group presented increased levels of catalase, lysozyme, superoxide dismutase, total antioxidant capacity, and glutathione peroxidase in the serum and intestines and decreased levels of malondialdehyde. RT–PCR revealed that SHS reduced the expression of intestinal proinflammatory factors and increased the expression of anti-inflammatory factors. SHS reduced the oxidative stress level in the head kidneys and maintained an intact tissue structure. Network pharmacology showed that quercetin, kaempferol, and emodin may be the main active compounds of SHS, while Bcl2 and Casp3 are core target proteins. SHS significantly affected the expression of bcl2 and casp3 in the fish intestine. Three compound components were quantitatively detected, and their binding to key proteins was confirmed by molecular docking and kinetic simulation. In summary, we explored the preventive effect and anti-inflammatory mechanism of SHS on common carp enteritis, providing a theoretical basis for further research on the rationality of using herbal medicines to replace feed antibiotics.

关键词： Bacterial enteritis Microbiota Molecular dynamics simulation Network pharmacology San-Huang-San

来源：评论

学校读者我要写书评

暂无评论

Corrigendum to “Strategies towards robust interpretations of in situ zircon oxygen isotopes”[***.14(2)(2023)101523]

引用

Geoscience Frontiers 2023年第6期14卷 496-496页

作者： Janne Liebmann Christopher L.Kirkland John B.Cliff Christopher J.Spencer Aaron J.Cavosie Timescales of Mineral Systems Group The Institute for Geoscience Research(TIGeR)School of Earth and Planetary SciencesCurtin UniversityPerthAustralia Pacific Northwest National Laboratory RichlandWA 99354United States Department of Geological Sciences and Geological Engineering Queen’s UniversityKingstonONCanada Space Science and Technology Centre The Institute for Geoscience Research(TIGeR)School of Earth and Planetary ScienceCurtin UniversityPerthAustralia

In the originally published version of our article(Liebmann et al.,2023),Table 2 incorrectly states that the publishedδ^(18)O value of reference zircon BR231 is 5.05‰±0.10‰.The correct value is 9.81‰±0.0... 详细信息

关键词： value zircon

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：