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International Seminar on Research of Information Technology and Intelligent Systems (ISRITI)

作者： Jason Sebastian Sulistyawan Kuncahyo Setyo Nugroho Bens Pardamean Computer Science Department BINUS Graduate Program Master of Computer Science Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331519643

ISBN: (纸本)9798331519650

Many smoking-related diseases are difficult to treat and often fatal. Rather than treating diseased smokers, preventing the diseased is more achievable, though, many of them deny to being smokers, leading to another problem. Thus, this study aims to detect important aspects that can detect that the person is a smoker or not through their bio-signals through using SHAP, along with a comprehensive analysis of the used methods, gradient-boosting algorithms XGBoost, LightGBM, and CatBoost, known for their efficiency in handling complex datasets and non-linear relationships. The study then found that triglyceride, Gtp, hemoglobins significantly affect the body's responses to smoking, based on the CatBoosts’ results, having an AUC score of up to 0.8612 and an accuracy score of up to 0.7776 with the selected features.

关键词： Seminars Measurement Accuracy Predictive models Feature extraction Boosting Physiology Classification algorithms Reliability Diseases

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A Hybrid Inference Engine to Predict Uncertain Sugar Content for Sugar Industry

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Procedia Computer science 2024年 245卷 480-489页

作者： Muhammad Asrol Napthaleni Ditdit Nugeraha Utama Suharjito Christian Harito Muhammad Syafrudin Industrial Engineering Department BINUS Graduate Program – Master of Industrial Engineering Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department BINUS Graduate Program – Master of Computer Science Bina Nusantara University Jakarta 11480 Indonesia Department of Artificial Intelligence and Data Science Sejong University Seoul 05006 South Korea

The sugar industry is facing challenges in increasing productivity to meet consumer demand. One opportunity for productivity improvement lies in ensuring sugar content. This study proposes a hybrid model to predict sugar content by considering uncertainty factors. A hybrid model combining fuzzy subtractive clustering, and a fuzzy inference system is proposed to predict sugar content. The clustering results using silhouette and fuzzy subtractive clustering successfully identified 6 cluster centres from 2225 datasets collected in a sugar industry in East Java Province. The hybrid inference engine model is designed with fuzzy rules derived from the clustered data. Two inference models are developed: triangular and Gaussian fuzzy numbers. The testing results indicate that the hybrid model with triangular fuzzy numbers shows the smallest error with an R2 value of 0.95. This model is possible to applied in the sugar industry for decision makers in improving productivity with taking attention into uncertain factors influencing sugar content.

关键词： Clustering Fuzzy Hybrid model Inference System Prediction Sugarcane

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Implementation of Fine-Tuned BERT for Enzyme Classification Based on Gene Ontology

Implementation of Fine-Tuned BERT for Enzyme Classification ...

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International Conference of Advanced Informatics: Concept, Theory and Application (ICAICTA)

作者： Matthew Martianus Henry Christian Kenneth Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331520311

ISBN: (纸本)9798331520328

Enzymes are biocatalysts with vital roles in biological functions and many industrial applications. Diverse enzymes are classified using Enzyme Commission (EC) nomenclature, making differentiation challenging. On the other hand, another biological information, gene ontology (GO), can describe the biological aspects of enzymes, covering related biological processes (BP), molecular functions (MF), and their locations within cells (CC). This study proposes a novel EC class and subclass classification of enzymes within the ontology subclass based on their GO semantics using a Bidirectional Encoder Representation of Transformer (BERT). The BERT model is first fine-tuned using the preprocessed GO term name and definition, with the enzymes in each ontology class (BP, MF, or CC) are also divided based on how the GO assigned, either through manual annotation (NONIEA) or electronically inferred (IEA). BERT successfully obtained 0.93, 0.60, 0.99, 0.90, 0.40, and 0.35 F1 scores during fine-tuning for BP IEA, BP NONIEA, MF IEA, MF NONIEA, CC IEA, and CC NONIEA, respectively. On the test set, the fine-tuned BERT significantly outperformed GOntoSim, a framework to calculate semantic similarity based on classical information theory, in EC class classification across all metrics with less inference time in all ontology subclass. Expanded further to the EC subclass, BERT can classify the enzyme on the EC subclass level in BP IEA and MF IEA ontology subclass. However, longer epochs are needed in fine-tuning. This result shows that the names and definitions of GO terms are distinguishable features in classifying enzymes as an alternative to the information content approach.

关键词： Measurement Enzymes Semantics Bidirectional control Manuals Ontologies Transformers Encoding Biological information theory Informatics

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Mitigating Berkson's Paradox with Neural Propensity Score Matching in E-Commerce Deals 6

Mitigating Berkson's Paradox with Neural Propensity Score Ma...

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6th International Conference on Cybernetics and Intelligent System, ICORIS 2024

作者： Dominic, Nicholas Pardamean, Bens Bina Nusantara University Bioinformatics and Data Science Research Center Jakarta Indonesia BINUS Graduate Program - Master of Computer Science Bina Nusantara University Computer Science Department Jakarta Indonesia

ISBN: (纸本)9798331539603

Within observational data science workloads, Berkson's paradox can lead to false causal inferences. One of the prominent quasi-experimental methods to mitigate this selection bias is Propensity Score Matching (PSM). An approach called Neural PSM (NPSM) was developed to overcome the drawbacks of conventional regression-based PSM, including its limited flexibility to model high-dimensional data and non-linear relationships that could cause imperfect covariate balance. In this study, a three-layer depth of Deep Neural Networks was designed to estimate propensity scores and finally balance both control and treatment groups of the Groupon dataset. An unsupervised k-Nearest Neighbor algorithm then helped the model to efficiently detect and cluster similar matching points. From the five salient features presented, NPSM successfully achieved lower differences in Cohen's d effect size, i.e., 0.313 for coupon duration, 0.017 for promotion length, 0.425 for quantity sold, -0.199 for limited supply, and 0.395 for Facebook likes. While these results mostly outperformed Linear Regression (LR) and Random Forest (RF) models, further evaluation is needed to verify the true effectiveness of NPSM in mitigating Berkson's paradox in broader e-commerce contexts. © 2024 IEEE.

关键词： Marketplaces

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Leveraging ChemBERTa Robustness in Drug-Drug Interaction Classification via Molecular Decomposition

Leveraging ChemBERTa Robustness in Drug-Drug Interaction Cla...

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International Seminar on Research of Information Technology and Intelligent Systems (ISRITI)

作者： Christian Kenneth Alyssa Imani Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program – Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331519643

ISBN: (纸本)9798331519650

Understanding drug-drug interactions (DDIs) can benefit us by enhancing drug effectiveness and preventing side effects that arise from consuming multiple drugs administered together. However, as the number of novel drugs increases, predicting potential DDIs becomes more challenging. Previous studies have used the molecular language model ChemBERTa to predict potential DDIs, but the predictions were only tested on unseen drugs and not dissimilar drugs, while also performing poorly. In this study, we demonstrate that a simple molecular preprocessing method using BRICS decomposition can enhance ChemBERTa robustness in predicting potential DDIs for unseen-dissimilar drugs. Specifically, we employ fragmentation with a minimum fragment size of 5 (BRICS-5), which balances the number of fragments and decomposition speed. Using this method, we were able to improve ChemBERTa robustness, reflected by an approximate increase of 1.5% in recall and 2.2% in the f1-score compared to non-decomposed molecules. Our findings suggest that this preprocessing method could be useful in the development of future AI-based approaches for solving challenging molecular tasks across different settings and various model architectures.

关键词： Drugs Seminars Accuracy data preprocessing Predictive models Robustness data models Intelligent systems Information technology

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A Hybrid CNN-SVM Approach for Malaria in Blood Cell Detection

A Hybrid CNN-SVM Approach for Malaria in Blood Cell Detectio...

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Software Engineering and Information Technology (ICoSEIT), International Conference on

作者： Andrea Stevens Karnyoto Mahmud Isnan Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia

There is still a severe malaria problem worldwide, particularly in regions with limited access to diagnostic tools. It is crucial to develop a system for detecting malaria in blood cells. This paper presents a hybrid Convolutional Neural Network (CNN), and as a classifier, we use a Support Vector Machine (SVM) framework for the automated detection of malaria parasites in blood cell images. The proposed system leverages the strengths of CNNs in feature extraction and representation learning from images, combined with the discriminative power of SVMs for classification. Initially, CNN extracts intricate features from blood cell images, capturing essential patterns indicative of malaria infection. Subsequently, the extracted features are used to train an SVM classifier, enabling accurate discrimination between parasitized and uninfected blood cells. Experimental dataset evaluations were obtained from the Lister Hill National Center for Biomedical Communications website of the National Library of Medicine. The proposed model achieves a better f1-score, outperforming individual CNN or SVM models, around 0.015 compared to individual CNN models and 0.27 compared to individual SVM models. This hybrid CNN-SVM methodology offers a promising solution for accurately and efficiently detecting malaria parasites in blood cell images.

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Ensuring Ethical, Transparent, and Auditable Use of Education data and Algorithms on AutoML 23

Ensuring Ethical, Transparent, and Auditable Use of Educatio...

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Proceedings of the 2023 6th International Conference on Machine Learning and Natural Language Processing

作者： Kylie Griep Leah Stone Stephen Edwards Malik Hill Jialin Cui Chengyuan Liu Qinjin Jia Yang Song Department of Computer Science University of North Carolina Wilmington USA Master of Data Science Program University of North Carolina Wilmington USA Department of Computer Science NC State University USA

ISBN: (纸本)9798400709241

Automated machine learning (AutoML) creates additional opportunities for less advanced users to build and test their own data mining models. Even though AutoML creates the models for the user, there is still technical knowledge and tools needed to evaluate those models, and due to the black-box nature of the machine learning models, problems can arise with regard to algorithmic biases and fairness. Such biases can escalate in future applications, necessitating a structured approach for fairness evaluation in AutoML. This involves defining fairness criteria, selecting appropriate metrics, assessing fairness across groups, and addressing biases. In the realm of educational data mining, where AutoML is prevalent, biases related to attributes like gender or race can lead to unethical outcomes. Since fairness metrics vary in definition and strength, and some may even contradict others, making fairness evaluation more complex. In this paper, ten fairness metrics were chosen, explored, and implemented on four AutoML tools, Vertex AI, AutoSklearn, AutoKeras, and PyCaret. We identified two open educational datasets and built both prediction and classification models on those AutoML frameworks. We report our work in evaluating different machine learning models created by AutoML and provide discussions about the challenges in evaluating fairness in those models and our effort to mitigate and resolve the problems of algorithmic bias in educational data mining.

关键词： AutoML Automated machine learning algorithmic bias educational data mining fairness

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Mitigating Berkson's Paradox with Neural Propensity Score Matching in E-Commerce Deals

Mitigating Berkson's Paradox with Neural Propensity Score Ma...

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International Conference on Cybernetics and Intelligent System (ICORIS)

作者： Nicholas Dominic Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program – Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331539603

ISBN: (纸本)9798331539610

关键词： Radio frequency Social networking (online) High dimensional data Linear regression Nearest neighbor methods data science Electronic commerce Intelligent systems Cybernetics Context modeling

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Systematic Literature Review on Metaheuristic Algorithms in SNP Analysis for Diseases

Systematic Literature Review on Metaheuristic Algorithms in ...

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International Conference on Cybernetics and Intelligent System (ICORIS)

作者： Jason Sebastian Sulistyawan Kuncahyo Setyo Nugroho Bens Pardamean Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331539603

ISBN: (纸本)9798331539610

Single-nucleotide polymorphism (SNP) analysis has become a pivotal strategy for drug discovery within bioinformatics, especially for incurable diseases like cancer. With the increasing number of researchers starting to embrace metaheuristic methods, a review was done by gathering papers from the Google Scholar database from 2018 to 2023, which resulted in 20 papers after title, abstract, and content filtering. The findings show that the Genetic Algorithm and the Harmony Search Algorithm have become popular approaches in SNP analysis, particularly in studies on breast cancer, age-related macular degeneration, and colorectal cancer. However, the review shows that while researchers have proven most methods effective in finding disease-related SNPs, a more measurable study in SNP analysis is needed, due to the lack of elaboration on measurement metrics in the found studies.

关键词： Macular degeneration Filtering databases Metaheuristics Time measurement Internet Drug discovery Intelligent systems Genetic algorithms Systematic literature review

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Knowledge Graph-Enhanced Semantic Cache for Low-Latency and Cost-Effective Inference in Large Language Models

Knowledge Graph-Enhanced Semantic Cache for Low-Latency and ...

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International Conference on Information Management and Technology (ICIMTech)

作者： Nicholas Dominic Bens Pardamean Bioinformatics & Data Science Research Center Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798350390025

ISBN: (纸本)9798350390032

In organizational knowledge management, Large Language Model (LLM) caches act as a semantic repository gathered from previous LLM responses. Due to intensive calls from multiple users, LLM may suffer from high inference latency. While there are many prior available approaches to solve this problem, most of them are inherently complex. This paper introduced a Knowledge Graph-enhanced Semantic Cache mechanism as an alternative, lightweight technique to boost retrieval for similar prompts. The latest state-of-the-art open-source LLM, named Google's Gemma-2B-it, was used to generate sample prompts and responses as a draft, while a knowledge graph (KG) was built from Wikipedia sentences. To create embeddings of prompts and KG, all-MiniLM-L6-v2 from SentenceTransformer was used. This new cache system resulted in up to 28% improvement over a standard model. In particular, reinforcement with KG cache embeddings yielded more than 85% semantic cache accuracy. To map the next trajectory of this pilot study, an overview of the extended framework for LLM knowledge management was also presented in this paper. The framework includes the new KG- enhanced cache system equipped with scalable security and fallback mechanisms that can promote green technology through substantial improvements in latency, throughput, and overall LLM costs.

关键词： Large language models Semantics Throughput Knowledge management Internet Trajectory Security Online services Low latency communication Standards

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