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arXiv 2020年

作者： Hiramatsu, Daichi Howell, D. Andrew van Dyk, Schuyler D. Goldberg, Jared A. Maeda, Keiichi Moriya, Takashi J. Tominaga, Nozomu Nomoto, Ken'ichi Hosseinzadeh, Griffin Arcavi, Iair McCully, Curtis Burke, Jamison Bostroem, K. Azalee Valenti, Stefano Dong, Yize Brown, Peter J. Andrews, Jennifer E. Bilinski, Christopher Williams, G. Grant Smith, Paul S. Smith, Nathan Sand, David J. Anand, Gagandeep S. Xu, Chengyuan Filippenko, Alexei V. Bersten, Melina C. Folatelli, Gastón Kelly, Patrick L. Noguchi, Toshihide Itagaki, Koichi Las Cumbres Observatory 6740 Cortona Drive Suite 102 GoletaCA93117-5575 United States Department of Physics University of California Santa BarbaraCA93106-9530 United States Caltech/Spitzer Science Center Caltech IPAC Mailcode 100-22 PasadenaCA91125 United States Department of Astronomy Kyoto University Kitashirakawa-Oiwake-cho Sakyo-ku Kyoto606-8502 Japan University of Tokyo Institutes for Advanced Study University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba277-8583 Japan National Astronomical Observatory of Japan National Institutes of Natural Sciences 2-21-1 Osawa Mitaka Tokyo181-8588 Japan School of Physics and Astronomy Faculty of Science Monash University ClaytonVIC3800 Australia Department of Physics Faculty of Science and Engineering Konan University 8-9-1 Okamoto Hyogo Kobe658-8501 Japan Center for Astrophysics Harvard & Smithsonian 60 Garden Street CambridgeMA02138-1516 United States School of Physics and Astronomy Tel Aviv University Tel Aviv69978 Israel CIFAR Azrieli Global Scholars Program CIFAR Toronto Canada Department of Physics University of California 1 Shields Ave DavisCA95616-5270 United States Mitchell Institute for Fundamental Physics and Astronomy Texas A&M University College StationTX77843 United States Steward Observatory University of Arizona 933 North Cherry Avenue TucsonAZ85721-0065 United States MMT Observatory P.O. Box 210065 TucsonAZ85721-0065 United States Infrared Processing and Analysis Center California Institute of Technology PasadenaCA91125 United States Institute for Astronomy University of Hawai'i 2680 Woodlawn Drive HonoluluHI96822 United States Media Arts and Technology University of California Santa BarbaraCA93106-6065 United States Department of Astronomy University of California BerkeleyCA94720-3411 United States Miller Institute for Basic Research in Science University of California BerkeleyCA94720 United States CONICET Argentina Facultad de Ciencias Astronómi

In the transitional mass range (∼ 8-10 solar masses) between white dwarf formation and iron core-collapse supernovae, stars are expected to produce an electron-capture supernova. Theoretically, these progenitors are thought to be super-asymptotic giant branch stars with a degenerate O+Ne+Mg core, and electron capture onto Ne and Mg nuclei should initiate core collapse1,2,3,4. However, no supernovae have unequivocally been identified from an electron-capture origin, partly because of uncertainty in theoretical predictions. Here we present six indicators of electron-capture supernovae and show that supernova 2018zd is the only known supernova having strong evidence for or consistent with all six: progenitor identification, circumstellar material, chemical composition5,6,7, explosion energy, light curve, and nucleosynthesis8,9,10,11,12. For supernova 2018zd, we infer a super-asymptotic giant branch progenitor based on the faint candidate in the pre-explosion images and the chemically-enriched circumstellar material revealed by the early ultraviolet colours and flash spectroscopy. The light-curve morphology and nebular emission lines can be explained by the low explosion energy and neutron-rich nucleosynthesis produced in an electron-capture supernova. This identification provides insights into the complex stellar evolution, supernova physics, cosmic nucleosynthesis, and remnant populations in the transitional mass range. Copyright © 2020, The Authors. All rights reserved.

关键词： Supernovae

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Promoting global education in science and engineering: An experience in Indonesian high schools

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Journal of Physics: Conference Series 2019年第1期1175卷

作者： F Triawan M K Biddinika S Hanaoka F Takahashi M Aziz Mechanical Engineering Study Program Sampoerna University Jl. Raya Pasar Minggu Kav 16 Jakarta Selatan 12780 Indonesia Department of Transdisciplinary Science and Engineering Tokyo Institute of Technology 2-12-1 Ookayama Meguro Tokyo 152-8550 Japan School of Environment and Society Tokyo Institute of Technology 4259 Nagatsuta Midori Yokohama 226-8503 Japan Center for Waste Management and Bioenergy Universitas Janabadra Jl. Tentara Rakyat Mataram 58 Bumijo Jetis Yogyakarta 55231 Indonesia Institute of Innovative Research Tokyo Institute of Technology 2-12-1 Ookayama Meguro Tokyo 152-8550 Japan

Japan has initiated higher education reform in which internationalization is one of the challenges as a way to improve excellence in research and competitiveness within Asia and the world. In becoming the 'Asian Gateway' to the rest of the world, Japan also invites students from Asian countries to pursue higher education in Japan. However, language problem is often considered as one of the barriers faced by international students – not only from Asian countries – in Japan, especially for undergraduate program since the program is mostly held in Japanese language. The Global Scientists and Engineers program (GSEP) is the international bachelor of engineering degree program in Tokyo Institute of Technology (Tokyo Tech). It does not require any Japanese language ability since the whole program would be taught in English. This paper presents the experience of promotional activities of the program in Indonesia in order to identify the challenges, to document the method, and to outline some recommendations for improvement. The promotion was held by presentation in front of 13 (thirteen) high schools in Jakarta and nearby. After the promotional presentation, participants were also requested to express their interest in applying the program as well as their perceived usefulness of the presentation.

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

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Nature 2024年第8003期627卷 347-357页

作者： Ken Suzuki Konstantinos Hatzikotoulas Lorraine Southam Henry J Taylor Xianyong Yin Kim M Lorenz Ravi Mandla Alicia Huerta-Chagoya Giorgio E M Melloni Stavroula Kanoni Nigel W Rayner Ozvan Bocher Ana Luiza Arruda Kyuto Sonehara Shinichi Namba Simon S K Lee Michael H Preuss Lauren E Petty Philip Schroeder Brett Vanderwerff Mart Kals Fiona Bragg Kuang Lin Xiuqing Guo Weihua Zhang Jie Yao Young Jin Kim Mariaelisa Graff Fumihiko Takeuchi Jana Nano Amel Lamri Masahiro Nakatochi Sanghoon Moon Robert A Scott James P Cook Jung-Jin Lee Ian Pan Daniel Taliun Esteban J Parra Jin-Fang Chai Lawrence F Bielak Yasuharu Tabara Yang Hai Gudmar Thorleifsson Niels Grarup Tamar Sofer Matthias Wuttke Chloé Sarnowski Christian Gieger Darryl Nousome Stella Trompet Soo-Heon Kwak Jirong Long Meng Sun Lin Tong Wei-Min Chen Suraj S Nongmaithem Raymond Noordam Victor J Y Lim Claudia H T Tam Yoonjung Yoonie Joo Chien-Hsiun Chen Laura M Raffield Bram Peter Prins Aude Nicolas Lisa R Yanek Guanjie Chen Jennifer A Brody Edmond Kabagambe Ping An Anny H Xiang Hyeok Sun Choi Brian E Cade Jingyi Tan K Alaine Broadaway Alice Williamson Zoha Kamali Jinrui Cui Manonanthini Thangam Linda S Adair Adebowale Adeyemo Carlos A Aguilar-Salinas Tarunveer S Ahluwalia Sonia S Anand Alain Bertoni Jette Bork-Jensen Ivan Brandslund Thomas A Buchanan Charles F Burant Adam S Butterworth Mickaël Canouil Juliana C N Chan Li-Ching Chang Miao-Li Chee Ji Chen Shyh-Huei Chen Yuan-Tsong Chen Zhengming Chen Lee-Ming Chuang Mary Cushman John Danesh Swapan K Das H Janaka de Silva George Dedoussis Latchezar Dimitrov Ayo P Doumatey Shufa Du Qing Duan Kai-Uwe Eckardt Leslie S Emery Daniel S Evans Michele K Evans Krista Fischer James S Floyd Ian Ford Oscar H Franco Timothy M Frayling Barry I Freedman Pauline Genter Hertzel C Gerstein Vilmantas Giedraitis Clicerio González-Villalpando Maria Elena González-Villalpando Penny Gordon-Larsen Myron Gross Lindsay A Guare Sophie Hackinger Liisa Hakaste Sohee Han Andrew T Hattersley Christian Herder Momoko Horikoshi Annie-Green Howard Willa Centre for Genetics and Genomics Versus Arthritis Centre for Musculoskeletal Research Division of Musculoskeletal and Dermatological Sciences University of Manchester Manchester UK. Department of Diabetes and Metabolic Diseases Graduate School of Medicine University of Tokyo Tokyo Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. konstantinos.hatzikotoulas@helmholtz-munich.de. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. Center for Precision Health Research National Human Genome Research Institute National Institutes of Health Bethesda MD USA. British Heart Foundation Cardiovascular Epidemiology Unit Department of Public Health and Primary Care University of Cambridge Cambridge UK. Heart and Lung Research Institute University of Cambridge Cambridge UK. Department of Epidemiology School of Public Health Nanjing Medical University Nanjing China. Department of Biostatistics and Center for Statistical Genetics University of Michigan Ann Arbor MI USA. Corporal Michael J. Crescenz VA Medical Center Philadelphia PA USA. Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Department of Genetics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Programs in Metabolism and Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA. Diabetes Unit and Center for Genomic Medicine Massachusetts General Hospital Boston MA USA. TIMI Study Group Division of Cardiovascular Medicine Brigham and Women's Hospital Harvard Medical School Boston MA USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London L

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (P < 5 × 10) that map to 611 loci, of which 145 loci are, to our knowledge, previously unreported. We define eight non-overlapping clusters of T2D signals that are characterized by distinct profiles of cardiometabolic trait associations. These clusters are differentially enriched for cell-type-specific regions of open chromatin, including pancreatic islets, adipocytes, endothelial cells and enteroendocrine cells. We build cluster-specific partitioned polygenic scores in a further 279,552 individuals of diverse ancestry, including 30,288 cases of T2D, and test their association with T2D-related vascular outcomes. Cluster-specific partitioned polygenic scores are associated with coronary artery disease, peripheral artery disease and end-stage diabetic nephropathy across ancestry groups, highlighting the importance of obesity-related processes in the development of vascular outcomes. Our findings show the value of integrating multi-ancestry genome-wide association study data with single-cell epigenomics to disentangle the aetiological heterogeneity that drives the development and progression of T2D. This might offer a route to optimize global access to genetically informed diabetes care.

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Web Application to Monitor Logistics Distribution of Disaster Relief Using the CodeIgniter Framework

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IOP Conference Series: Materials science and engineering 2018年第1期325卷

作者： Mohamad Jamil Mohamad Ridwan Lessy Departement Informatics Engineering Faculty of Engineering Universitas Khairun .Jl. Pertamina Kampus II Unkhair Gambesi Kota Ternate Maluku Utara Indonesia 97719 Departement Marine Science Study Program Faculty of Fisheries Universitas Khairun Jl. Pertamina Kampus II Unkhair Gambesi Kota Ternate Maluku Utara Indonesia 97719

Disaster management is the responsibility of the central government and local governments. The principles of disaster management, among others, are quick and precise, priorities, coordination and cohesion, efficient and effective manner. Help that is needed by most societies are logistical assistance, such as the assistance covers people's everyday needs, such as food, instant noodles, fast food, blankets, mattresses etc. Logistical assistance is needed for disaster management, especially in times of disasters. The support of logistical assistance must be timely, to the right location, target, quality, quantity, and needs. The purpose of this study is to make a web application to monitorlogistics distribution of disaster relefusing CodeIgniter framework. Through this application, the mechanisms of aid delivery will be easily controlled from and heading to the disaster site.

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Computation of resistance and potential of grounding grids in any geometry 16

Computation of resistance and potential of grounding grids i...

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16th International Conference on Environment and Electrical engineering, EEEIC 2016

作者： Pires, Thyago G. Nerys, Jose W. L. Silva, Carlos L. B. Oliveira, Diogo N. Filho, Antonio M. Silva Calixto, Wesley P. Alves, Aylton J. School of Electric and Computing Engineering Federal University of Goias Goiania Brazil Graduate Program in Electronic and Automation Systems Engineering University of Brasilia Brasilia Brazil Experimental and Technologic Research and Study Group Federal Institute of Education Science and Technology Goiania Brazil

ISBN: (纸本)9781509023196

This paper deals with the computation of ground resistance, surface voltage, touch voltage and step voltage, to mesh with horizontal wires arranged in different angles. The computer program implemented used in the mathematical modeling is based on the method proposed by Heppe, which allows obtaining the grounding parameters for homogeneous soil and soil stratified in two layers. The results obtained with the proposed method will be compared with other methods in literature. Also will be presented the results of a grounding grid using wires at various angles. © 2016 IEEE.

关键词： Mesh generation

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Optimization of grounding grid's multidesign geometry 16

Optimization of grounding grid's multidesign geometry

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16th International Conference on Environment and Electrical engineering, EEEIC 2016

作者： Silva, Carlos L. B. Oliveira, Diogo N. Pires, Thyago G. Nerys, Jose W. L. Barbosa, Paulo H. S. Calixto, Wesley P. Alves, Aylton J. Graduate Program in Electronic and Automation Systems Engineering University of Brasilia Brasilia Brazil School of Electric and Computing Engineering Federal University of Goias Goiania Brazil Experimental Technologic Research and Study Group Federal Institute of Education Science and Technology Goiania Brazil

ISBN: (纸本)9781509023196

This paper deals with the optimization of grounding grids geometry. The goal is to reduce the amount of material to deploy a grounding grid, while keeping the system security. The touch voltages, step voltages, GPR and ground resistance are parameters of grounding grids and are related to safety aspect. Also discussed is a genetic algorithm used for optimizing ground grids, which can assume any form in a limited space of the project. The simulation is based in images method. The results are presented and discussed. © 2016 IEEE.

关键词： Ground penetrating radar systems

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Search for Gravitational Waves Emitted from SN2023ixf

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Astrophysical Journal 2025年第2期985卷 183-183页

作者： Abac, A.G. Abbott, R. Abouelfettouh, I. Acernese, F. Ackley, K. Adhicary, S. Adhikari, N. Adhikari, R.X. Adkins, V.K. Agarwal, D. Agathos, M. Aghaei Abchouyeh, M. Aguiar, O.D. Aguilar, I. Aiello, L. Ain, A. Akutsu, T. Albanesi, S. Alfaidi, R.A. Al-Jodah, A. Alléné, C. Allocca, A. Al-Shammari, S. Altin, P.A. Alvarez-Lopez, S. Amato, A. Amez-Droz, L. Amorosi, A. Amra, C. Ananyeva, A. Anderson, S.B. Anderson, W.G. Andia, M. Ando, M. Andrade, T. Andres, N. Andrés-Carcasona, M. Andrić, T. Anglin, J. Ansoldi, S. Antelis, J.M. Antier, S. Aoumi, M. Appavuravther, E.Z. Appert, S. Apple, S.K. Arai, K. Araya, A. Araya, M.C. Areeda, J.S. Argianas, L. Aritomi, N. Armato, F. Arnaud, N. Arogeti, M. Aronson, S.M. Ashton, G. Aso, Y. Assiduo, M. Assis de Souza Melo, S. Aston, S.M. Astone, P. Attadio, F. Aubin, F. AultONeal, K. Avallone, G. Babak, S. Badaracco, F. Badger, C. Bae, S. Bagnasco, S. Bagui, E. Baier, J.G. Baiotti, L. Bajpai, R. Baka, T. Ball, M. Ballardin, G. Ballmer, S.W. Banagiri, S. Banerjee, B. Bankar, D. Baral, P. Barayoga, J.C. Barish, B.C. Barker, D. Barneo, P. Barone, F. Barr, B. Barsotti, L. Barsuglia, M. Barta, D. Bartoletti, A.M. Barton, M.A. Bartos, I. Basak, S. Basalaev, A. Bassiri, R. Basti, A. Bates, D.E. Bawaj, M. Baxi, P. Bayley, J.C. Baylor, A.C. Baynard, P.A. Bazzan, M. Bedakihale, V.M. Beirnaert, F. Bejger, M. Belardinelli, D. Bell, A.S. Benedetto, V. Benoit, W. Bentley, J.D. Ben Yaala, M. Bera, S. Berbel, M. Bergamin, F. Berger, B.K. Bernuzzi, S. Beroiz, M. Bersanetti, D. Bertolini, A. Betzwieser, J. Beveridge, D. Bevins, N. Bhandare, R. Bhardwaj, U. Bhatt, R. Bhattacharjee, D. Bhaumik, S. Bhowmick, S. Bianchi, A. Bilenko, I.A. Billingsley, G. Binetti, A. Bini, S. Birnholtz, O. Biscoveanu, S. Bisht, A. Bitossi, M. Bizouard, M.-A. Blackburn, J.K. Blagg, L.A. Blair, C.D. Blair, D.G. Bobba, F. Bode, N. Boileau, G. Boldrini, M. Bolingbroke, G.N. Bolliand, A. Bonavena, L.D. Bondarescu, R. Bondu, F. Bonilla, E. Bonilla, M.S. Bonino, A. Bonnand, R. Booker, P. Borchers, A. Boschi, V. Bose, S. Bossilkov, V. Max Planck Institute for Gravitational Physics (Albert Einstein Institute) Potsdam D-14476 Germany LIGO Laboratory California Institute of Technology Pasadena 91125 CA United States LIGO Hanford Observatory Richland 99352 WA United States Dipartimento di Farmacia Università di Salerno Fisciano Salerno I-84084 Italy INFN Sezione di Napoli Napoli I-80126 Italy University of Warwick Coventry CV4 7AL United Kingdom The Pennsylvania State University University Park 16802 PA United States University of Wisconsin-Milwaukee Milwaukee 53201 WI United States Louisiana State University Baton Rouge 70803 LA United States Université catholique de Louvain Louvain-la-Neuve B-1348 Belgium Inter-University Centre for Astronomy and Astrophysics Pune 411007 India Queen Mary University of London London E1 4NS United Kingdom Department of Physics and Astronomy Sejong University 209 Neungdongro Gwangjin-gu Seoul 143-747 South Korea Instituto Nacional de Pesquisas Espaciais São José dos Campos São Paulo 12227-010 Brazil Stanford University Stanford 94305 CA United States Università di Roma Tor Vergata Roma I-00133 Italy INFN Sezione di Roma Tor Vergata Roma I-00133 Italy Cardiff University Cardiff CF24 3AA United Kingdom Universiteit Antwerpen Antwerpen 2000 Belgium Gravitational Wave Science Project National Astronomical Observatory of Japan Mitaka City 2-21-1 Osawa Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan Mitaka City 2-21-1 Osawa Tokyo 181-8588 Japan INFN Sezione di Torino Torino I-10125 Italy Theoretisch-Physikalisches Institut Friedrich-Schiller-Universität Jena Jena D-07743 Germany Dipartimento di Fisica Università degli Studi di Torino Torino I-10125 Italy SUPA University of Glasgow Glasgow G12 8QQ United Kingdom OzGrav University of Western Australia Crawley 6009 WA Australia University Savoie Mont Blanc CNRS Laboratoire d’Annecy de Physique des Particules IN2P3 Annecy F-7

We present the results of a search for gravitational-wave transients associated with core-collapse supernova SN 2023ixf, which was observed in the galaxy Messier 101 via optical emission on 2023 May 19, during the LIGO–Virgo–KAGRA 15th engineering Run. We define a five-day on-source window during which an accompanying gravitational-wave signal may have occurred. No gravitational waves have been identified in data when at least two gravitational-wave observatories were operating, which covered ∼14% of this five-day window. We report the search detection efficiency for various possible gravitational-wave emission models. Considering the distance to M101 (6.7 Mpc), we derive constraints on the gravitational-wave emission mechanism of core-collapse supernovae across a broad frequency spectrum, ranging from 50 Hz to 2 kHz, where we assume the gravitational-wave emission occurred when coincident data are available in the on-source window. Considering an ellipsoid model for a rotating proto-neutron star, our search is sensitive to gravitational-wave energy 1 × 10⁻⁴ M_⊙c² and luminosity 2.6 × 10⁻⁴ M_⊙c² s⁻¹ for a source emitting at 82 Hz. These constraints are around an order of magnitude more stringent than those obtained so far with gravitational-wave data. The constraint on the ellipticity of the proto-neutron star that is formed is as low as 1.08, at frequencies above 1200 Hz, surpassing past results. © 2025. The Author(s).

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Open Data from the Third Observing Run of LIGO, Virgo, KAGRA, and GEO

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Astrophysical Journal, Supplement Series 2023年第2期267卷 29-29页

作者： Abbott, R. Abe, H. Acernese, F. Ackley, K. Adhicary, S. Adhikari, N. Adhikari, R.X. Adkins, V.K. Adya, V.B. Affeldt, C. Agarwal, D. Agathos, M. Aguiar, O.D. Aiello, L. Ain, A. Ajith, P. Akutsu, T. Albanesi, S. Alfaidi, R.A. Al-Jodah, A. Alléné, C. Allocca, A. Almualla, M. Altin, P.A. Amato, A. Amez-Droz, L. Amorosi, A. Anand, S. Ananyeva, A. Andersen, R. Anderson, S.B. Anderson, W.G. Andia, M. Ando, M. Andrade, T. Andres, N. Andrés-Carcasona, M. Andrić, T. Ansoldi, S. Antelis, J.M. Antier, S. Aoumi, M. Apostolatos, T. Appavuravther, E.Z. Appert, S. Apple, S.K. Arai, K. Araya, A. Araya, M.C. Areeda, J.S. Arène, M. Aritomi, N. Arnaud, N. Arogeti, M. Aronson, S.M. Arun, K.G. Asada, H. Ashton, G. Aso, Y. Assiduo, M. Assis de Souza Melo, S. Aston, S.M. Astone, P. Aubin, F. AultONeal, K. Babak, S. Badalyan, A. Badaracco, F. Badger, C. Bae, S. Bagnasco, S. Bai, Y. Baier, J.G. Baiotti, L. Baird, J. Bajpai, R. Baka, T. Ball, M. Ballardin, G. Ballmer, S.W. Baltus, G. Banagiri, S. Banerjee, B. Bankar, D. Baral, P. Barayoga, J.C. Barber, J. Barish, B.C. Barker, D. Barneo, P. Barone, F. Barr, B. Barsotti, L. Barsuglia, M. Barta, D. Barthelmy, S.D. Barton, M.A. Bartos, I. Basak, S. Basalaev, A. Bassiri, R. Basti, A. Bawaj, M. Bayley, J.C. Baylor, A.C. Bazzan, M. Bécsy, B. Bedakihale, V.M. Beirnaert, F. Bejger, M. Bell, A.S. Benedetto, V. Beniwal, D. Benoit, W. Bentley, J.D. Ben Yaala, M. Bera, S. Berbel, M. Bergamin, F. Berger, B.K. Bernuzzi, S. Beroiz, M. Berry, C.P.L. Bersanetti, D. Bertolini, A. Betzwieser, J. Beveridge, D. Bevins, N. Bhandare, R. Bhandari, A.V. Bhardwaj, U. Bhatt, R. Bhattacharjee, D. Bhaumik, S. Bianchi, A. Bilenko, I.A. Bilicki, M. Billingsley, G. Bini, S. Birnholtz, O. Biscans, S. Bischi, M. Biscoveanu, S. Bisht, A. Biswas, B. Bitossi, M. Bizouard, M.-A. Blackburn, J.K. Blair, C.D. Blair, D.G. Blair, R.M. Bobba, F. Bode, N. Boër, M. Bogaert, G. Boileau, G. Boldrini, M. Bolingbroke, G.N. Bonavena, L.D. Bondarescu, R. Bondu, F. Bonilla, E. Bonilla, G.S. Bonnand, R. Booker, P. Bork, R. Boschi, V. Bose, N. LIGO Laboratory California Institute of Technology Pasadena 91125 CA United States Graduate School of Science Tokyo Institute of Technology 2-12-1 Ookayama Meguro-ku Tokyo 152-8551 Japan Dipartimento di Farmacia Università di Salerno Salerno Fisciano I-84084 Italy INFN Sezione di Napoli Napoli I-80126 Italy OzGrav School of Physics & Astronomy Monash University Clayton 3800 VIC Australia The Pennsylvania State University University Park 16802 PA United States University of Wisconsin-Milwaukee Milwaukee 53201 WI United States Louisiana State University Baton Rouge 70803 LA United States OzGrav Australian National University Canberra 0200 ACT Australia Max Planck Institute for Gravitational Physics (Albert Einstein Institute) Hannover D-30167 Germany Leibniz Universität Hannover Hannover D-30167 Germany Inter-University Centre for Astronomy and Astrophysics Pune 411007 India University of Cambridge Cambridge CB2 1TN United Kingdom Instituto Nacional de Pesquisas Espaciais São Paulo São José dos Campos 12227-010 Brazil Cardiff University Cardiff CF24 3AA United Kingdom INFN Sezione di Pisa Pisa I-56127 Italy International Centre for Theoretical Sciences Tata Institute of Fundamental Research Bengaluru 560089 India Gravitational Wave Science Project National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Dipartimento di Fisica Università degli Studi di Torino Torino I-10125 Italy INFN Sezione di Torino Torino I-10125 Italy SUPA University of Glasgow Glasgow G12 8QQ United Kingdom OzGrav University of Western Australia Crawley 6009 WA Australia Univ. Savoie Mont Blanc CNRS Laboratoire d'Annecy de Physique des Particules - IN2P3 Annecy F-74000 France Università di Napoli “Federico II” Napoli I-80126 Italy University of Minnesota Minneapolis 55455 MN United States M

The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open science Center at https://***. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages. © 2023. The Author(s). Published by the American Astronomical Society.

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Formation of Mount Loyang: Easternmost scoria cone of Slamet stratovolcano, Central Java, Indonesia

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AIP Conference Proceedings 2018年第1期1987卷

作者： A. Harijoko R. M. P. P. Gunawan H. E. Wibowo N. I. Setiawan E. Handini W. Suryanto E. T. W. Mei 1Geological Engineering Department Engineering Faculty Universitas Gadjah Mada Indonesia 2Volcanology Research Group LPPT Universitas Gadjah Mada Indonesia 3GAMA-InaTEK Universitas Gadjah Mada Indonesia 4Study Program of Geophysic Faculty of Science and Mathematic Universitas Gadjah Mada Indonesia 5Faculty of Geography Universitas Gadjah Mada Indonesia

Scoria cones commonly occur in the lower flank of stratovolcano close to the populated area. This close spatial relationship increases hazardous risk of direct impact of volcanic activities to the people. Therefore, it is necessary to gain more understanding to the formation of scoria cone to better assess the volcanic hazards. We studied Mount Loyang, the furthest scoria cone of Slamet volcano, approximately 14 km from the recent active crater. Quarrying to this scoria cone enables us to observe the interior structure towards the surface as represented by its volcanic rocks sequence. The sequences include 61 layers of voluminous ash and lapilli deposits resembling simultaneous scoria cone formation which attributed with lava effusion on the lower part of the cone. Chemical compositions were gained through ICP-MS-AES analysis including major and 13 trace elements for 17 representative samples yields typical basaltic compositions of SiO2 46.1 to 50.7 wt.% and MgO 5.9 to 7.5 wt.%. Median grain size (MdΦ) and sortation coefficient (δΦ) of −0.4 to −1.85 and 1.025 to 2.35, respectively, suggested for Hawaiian to Strombolian eruption type. In detailed, initial stage composed of bomb rich (size range 10 to 30 cm) embedded in ash materials (Φ scale −2) typical of opening vent stage. Average grain size shows general coarsening upward trend (Φ scale −3 to −5) and suggest for increasing explosive eruptive style. In the late stage, pyroclastic surge deposit typical of phreatomagmatic eruptive style started occur implying for the transition from dry to wet environment. The external water influence might triggered more explosive eruptive style once there is new magma ascend to the surface. We suggest that such eruptive style through a scoria cone need to be integrated into the hazard assessment of a potentially active volcanic area such as that in Slamet volcano.

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Pathway-based genome analysis of cognitive impairment in a forager-horticulturalist South American population

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Alzheimer's & Dementia 2022年第S4期18卷

作者： Angela R Garcia Yih-Kuang Lu Margaret Gatz Daniel Eid Rodriguez Raul Quispe Gutierrez Juan J Copajira Adrian Jesus Bani Cuata M Linda Sutherland James D Sutherland Daniel K Cummings Thomas Kraft Wendy J Mack Helena C Chui Meng Law Giuseppe Barisano Amy R Borenstein Andrei Irimia Ellen E Walters Gregory S Thomas Randall C Thompson Michael I Miyamoto David E Michalik L Samuel Wann Adel H Allam Christopher J Rowan Heather M Highland Kari E North Caleb E Finch Jonathan Stieglitz Michael D Gurven Benjamin C Trumble Hillard Kaplan Kenneth Buetow Arizona State University Tempe AZ USA Phoenix Children’s Hospital Phoenix AZ USA Center for Economic and Social Research University of Southern California Los Angeles CA USA San Simon University (Plurinational State of) Cochabamba Bolivia Tsimane Health and Life History Project (Plurinational State of) Beni Bolivia Tsimane Health and Life History Project (Plurinational State of) San Borja Bolivia Memorial Care Heart Systems Fountain Valley CA USA Memorial Care Health Systems Fountain Valley CA USA Chapman University Orange CA USA University of Utah Salt Lake City UT USA Department of Population and Public Health Sciences Keck School of Medicine University of Southern California Los Angeles CA USA University of Southern California Los Angeles CA USA Monash University Melbourne Australia Neuroscience Graduate Program University of Southern California Los Angeles CA USA University of California San Diego San Diego CA USA Viterbi School of Engineering University of Southern California Los Angeles CA USA Leonard Davis School of Gerontology University of Southern California Los Angeles CA USA Memorial Care Heart & Vascular Institute Fountain Valley CA USA University of Missouri City Kansas Kansas City MO USA Mission Heritage Medical Group Health Providence Mission Viejo CA USA MemorialCare Miller Women’s and Children’s Hospital Long Beach CA USA University of California at Irvine Orange CA USA University of New Mexico Albuquerque NM USA Al Azhar University Cairo Egypt Renown Institute for Heart and Vascular Health Reno NV USA University of North Carolina Chapel Hill NC USA USC Dornsife College of Letters Arts and Sciences Los Angeles CA USA Institute for Advanced Study in Toulouse Toulouse France University of California Santa Barbara Santa Barbara CA USA Economic Science Institute Argyros School of Business and Economics Chapman University Orange CA USA

Background The genetic etiology of Cognitive Impairment (CI) is poorly understood. This is due, in part, to the complexity of diverse genetic and environmental risk factors in large, heterogeneous study populations. To overcome this obstacle, we examined a population with low genetic heterogeneity and fewer risk factors commonly found in industrialized populations - the Tsimane of Bolivia (N = 353; mean age = 69 years [60–93 years]). The Tsimane are a geographically isolated forager-horticulturalist population with high levels of physical activity and low prevalence of coronary artery disease, hypertension, and diabetes, even at advanced ages. The absence of these typical Alzheimer’s Disease (AD)-related comorbidities provides a novel opportunity to isolate aspects of CI that are often intertwined with cardiometabolic and other non-communicable chronic diseases. Method CI was determined from field evaluations using a locally translated and adapted cognitive battery, mental status examination, informant interview, and neurological evaluation (CI = 31, AD = 1). Genome-wide variation was characterized using the Infinum Multi-Ethnic Global Array (1,754,170 SNPs) and evaluated with a novel analytic tool that uses biologic processes as the unit of analysis — Pathways of Distinction Analysis (PoDA). PoDA captures interactions across the multiple genes within a network and assesses significance via empiric resampling. A catalog of 1167 curated networks representing the diversity of biologic function was evaluated. Result The pathway that most significantly distinguishes individuals with CI from those without impairment is the KEGG Alzheimer’s Disease Pathway (Distance Score [DS] = 3.23; FDR-adjusted pDS<0.001). This pathway is composed of 169 genes that capture the major processes associated with AD. Refined analysis identified a subset of 35 genes that is associated with a 6-fold difference (OR = 6.26; pOR = 1.21×10 −12 ) in relative risk for prevalent CI vs. no impairment

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