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AMHF-TP: Multifunctional therapeutic peptides prediction based on multi-granularity hierarchical features

Quantitative Biology 2025年第01期 44-58页

作者： Shouheng Tuo YanLing Zhu Jiangkun Lin Jiewei Jiang School of Computer Science and Technology Xi'an University of Posts and Telecommunications Shaanxi Key Laboratory of Network Data Analysis and Intelligent Processing Xi'an Key Laboratory of Big Data and Intelligent Computing School of Electronic Engineering Xi'an University of Posts and Telecommunications

Multifunctional therapeutic peptides(MFTP) hold immense potential in diverse therapeutic contexts, yet their prediction and identification remain challenging due to the limitations of traditional methodologies, such as extensive training durations, limited sample sizes, and inadequate generalization capabilities. To address these issues, we present AMHF-TP, an advanced method for MFTP recognition that utilizes attention mechanisms and multi-granularity hierarchical features to enhance performance. The AMHF-TP is composed of four key components: a migration learning module that leverages pretrained models to extract atomic compositional features of MFTP sequences; a convolutional neural network and selfattention module that refine feature extraction from amino acid sequences and their secondary structures; a hypergraph module that constructs a hypergraph for complex similarity representation between MFTP sequences; and a hierarchical feature extraction module that integrates multimodal peptide sequence features. Compared with leading methods,the proposed AMHF-TP demonstrates superior precision, accuracy, and coverage, underscoring its effectiveness and robustness in MFTP recognition. The comparative analysis of separate hierarchical models and the combined model, as well as with five contemporary models, reveals AMHF-TP's exceptional performance and stability in recognition tasks.

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Source-free Domain Adaptation with Multiple Alignment for Efficient Image Retrieval

Source-free Domain Adaptation with Multiple Alignment for Ef...

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2025 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2025

作者： Ni, Jinghui Cui, Hui Zhao, Lihai Li, Fengling Han, Xiaohui Xu, Lijuan Key Laboratory of Computing Power Network and Information Security Ministry of Education Shandong Computer Science Center Qilu University of Technology Shandong Academy of Sciences China Shandong Provincial Key Laboratory of Industrial Network and Information System Security Shandong Fundamental Research Center for Computer Science China Quan Cheng Laboratory China Shandong Open University China University of Technology Sydney Australia

ISBN: (纸本)9798350368741

Domain adaptation techniques help models generalize to target domains by addressing domain discrepancies between the source and target domain data distributions. These techniques are particularly valuable for cross-domain hashing retrieval, as they reduce training costs while maintaining high retrieval efficiency. However, existing unsupervised domain adaptative hashing methods often require access to both source and target domain data, which may raise privacy concerns regarding source domain data. To address these concerns, restricting access to source domain data is crucial, but this restriction also makes the alignment process between domains more challenging. In this paper, we propose a Source-free Domain Adaptive Hashing with Multiple Alignment (SFDAH-MA) approach for image retrieval. SFDAH-MA integrates model structure alignment, class moment alignment, and semantic relationship alignment to maximize inter-domain knowledge transfer. This comprehensive alignment strategy not only enhances retrieval performance across domains but also minimizes reliance on source domain data, thereby supporting data privacy protection. Extensive experiments show that SFDAH-MA achieves state-of-the-art performance in source-free settings and achieves comparable results to existing unsupervised domain adaptive hashing methods under conventional settings. The source codes of our method are available at: https://***/Nikphyc/SFDAH-MA. © 2025 IEEE.

关键词： Deep hashing image retrieval source-free domain adaptation

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Riemannian Complex Hermit Positive Definite Convolution network for Polarimetric SAR Image Classification

arXiv

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arXiv 2025年

作者： Shi, Junfei Nie, Mengmeng Li, Yuke Jin, Haiyan Lin, Weisi Department of Computer Science and Technology Shaanxi Key Laboratory for Network Computing and Security Technology Xi’an University of Technology Xi’an China College of Computing and Data Science Nanyang Technological University 639798 Singapore

Deep learning can learn high-level semantic features in Euclidean space effectively for PolSAR images, while they need to covert the complex covariance matrix into a feature vector or complex-valued vector as the network input. However, the complex covariance matrices are essentially a complex Hermit positive definite (HPD) matrix endowed in Riemannian manifold rather than Euclidean space. The matrix’s real and imagery parts are with the same significance, as the imagery part represents the phase information. The matrix vectorization will destroy the geometric structure and manifold characteristics of complex covariance matrices. To learn complex HPD matrices directly, we propose a Riemannian complex HPD convolution network(HPD CNN) for PolSAR images. This method consists of a complex HPD unfolding network(HPDnet) and a CV-3DCNN enhanced network. The proposed complex HPDnet defines the HPD mapping, rectifying and the logEig layers to learn geometric features of complex matrices. In addition, a fast eigenvalue decomposition method is designed to reduce computation burden. Finally, a Riemannian-to-Euclidean enhanced network is defined to enhance contextual information for classification. Experimental results on two real PolSSAR datasets demonstrate the proposed method can achieve superior performance than the state-of-the-art methods especially in heterogeneous regions. Copyright © 2025, The Authors. All rights reserved.

关键词： Convolution

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A Byzantine Client Detection Method for Federated Learning Based on Encrypted Repeated Median Linear Regression 24

A Byzantine Client Detection Method for Federated Learning B...

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5th International Conference on Computer Science and Management technology, ICCSMT 2024

作者： Guo, Jinlong Yang, Ming Li, Huijuan Wu, Xiaoming He, Yunpeng Wang, Xin Key Laboratory of Computing Power Network and Information Security Ministry of Education Shandong Computer Science Center Qilu University of Technology Shandong Academy of Sciences Shandong Jinan China Shandong Evayinfo Technology Co. Ltd. Shandong Jinan China

ISBN: (纸本)9798400709999

Federated learning is an emerging distributed machine learning technology that allows participants to jointly train machine learning models locally without the need for large-scale data transmission and sharing, thereby greatly improving data security. However, some Byzantine clients may intentionally tamper with local model parameter updates with the intention of manipulating the global model's update direction, which can lead to a decline in the overall performance of federated learning. Besides, existing Byzantine client detection research is conducted in plain text, which will lead to the leakage of private information. To solve the above issues, we propose a Byzantine client detection method for federated learning based on encrypted repeated median linear regression. Specifically, it combines the repeated median linear regression algorithm with homomorphic encryption, which can detect and eliminate clients with Byzantine behavior in the ciphertext state, ensuring the security and reliability of the parameters in the entire federated learning process. Additionally, we also designed an adaptive gradient clipping method based on historical iteration to clip the gradient to a reasonable range, which can not only reduce communication and computing overhead, but also improve the convergence speed and stability of the model. Experiments show that the proposed method can maintain high accuracy under the influence of malicious behavior of Byzantine clients. © 2024 Copyright held by the owner/author(s). Publication rights licensed to ACM.

关键词： Federated learning

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CroPrompt: Cross-task Interactive Prompting for Zero-shot Spoken Language Understanding

CroPrompt: Cross-task Interactive Prompting for Zero-shot Sp...

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2025 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2025

作者： Qin, Libo Wei, Fuxuan Chen, Qiguang Zhou, Jingxuan Huang, Shijue Si, Jiasheng Lu, Wenpeng Che, Wanxiang School of Computer Science and Engineering Central South University China Key Laboratory of Data Intelligence and Advanced Computing in Provincial Universities Soochow University China Research Center for Social Computing and Information Retrieval Harbin Institute of Technology China Harbin Institute of Technology Shenzhen China Key Laboratory of Computing Power Network and Information Security Ministry of Education Qilu University of Technology Shandong Academy of Sciences China

ISBN: (纸本)9798350368741

Slot filling and intent detection are two highly correlated tasks in spoken language understanding (SLU). Recent SLU research attempts to explore zero-shot prompting techniques in large language models to alleviate the data scarcity problem. Nevertheless, the existing prompting work ignores the cross-task interaction information for SLU, which leads to sub-optimal performance. To solve this problem, we present the pioneering work of Cross-task Interactive Prompting (CroPrompt) for SLU, which enables the model to interactively leverage the information exchange across the correlated tasks in SLU. Additionally, we further introduce a multi-task self-consistency mechanism to mitigate the error propagation caused by the intent information injection. We conduct extensive experiments on the standard SLU benchmark and the results reveal that CroPrompt consistently outperforms the existing prompting approaches. In addition, the multi-task self-consistency mechanism can effectively ease the error propagation issue, thereby enhancing the performance. We hope this work can inspire more research on cross-task prompting for SLU. © 2025 IEEE.

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A Novel Riemannian Sparse Representation Learning network for Polarimetric SAR Image Classification

arXiv

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arXiv 2025年

作者： Shi, Junfei Nie, Mengmeng Lin, Weisi Jin, Haiyan Li, Junhuai Wang, Rui The Department of Computer Science and Technology Shaanxi Key Laboratory for Network Computing and Security Technology Xi’an University of Technology Xi’an China The Department of Computer Science and Technology Shaanxi Key Laboratory for Network Computing and Security Technology Xi’an University of Technology Xi’an710048 China the School of Computer Science and Engineering Nanyang Technological University 639798 Singapore The School of Artificial Intelligence and Computer Science Jiangnan University Wuxi214122 China

Deep learning is an effective end-to-end method for Polarimetric Synthetic Aperture Radar(PolSAR) image classification, but it lacks the guidance of related mathematical principle and is essentially a black-box model. In addition, existing deep models learn features in Euclidean space, where PolSAR complex matrix is commonly converted into a complex-valued vector as the network input, distorting matrix structure and channel relationship. However, the complex covariance matrix is Hermitian positive definite (HPD), and resides on a Riemannian manifold instead of a Euclidean one. Existing methods cannot measure the geometric distance of HPD matrices and easily cause some misclassifications due to inappropriate Euclidean measures. To address these issues, we propose a novel Riemannian Sparse Representation Learning network (SRSR_CNN) for PolSAR images. Firstly, a superpixel-based Riemannian Sparse Representation (SRSR) model is designed to learn the sparse features with Riemannian metric. Then, the optimization procedure of the SRSR model is inferred and further unfolded into an SRSRnet, which can automatically learn the sparse coefficients and dictionary atoms. Furthermore, to learn contextual high-level features, a CNN-enhanced module is added to improve classification performance. The proposed network is a Sparse Representation (SR) guided deep learning model, which can directly utilize the covariance matrix as the network input, and utilize Riemannian metric to learn geometric structure and sparse features of complex matrices in Riemannian space. Experiments on three real PolSAR datasets demonstrate that the proposed method surpasses state-of-the-art techniques in ensuring accurate edge details and correct region homogeneity for classification. Copyright © 2025, The Authors. All rights reserved.

关键词： Covariance matrix

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CurMIM: Curriculum Masked Image Modeling

CurMIM: Curriculum Masked Image Modeling

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2025 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2025

作者： Liu, Hao Wang, Kun Han, Yudong Wang, Haocong Hu, Yupeng Wang, Chunxiao Nie, Liqiang School of Software Shandong University Jinan China Key Laboratory of Computing Power Network and Information Security Ministry of Education Qilu University of Technology Shandong Academy of Sciences Jinan China School of Computer Science and Technology Harbin Institute of Technology Shenzhen China

ISBN: (纸本)9798350368741

Masked Image Modeling (MIM), following "mask-and-reconstruct" scheme, is a promising self-supervised method to learn scalable visual representation. Studies indicate that selecting an effective mask strategy is vital for MIM. However, existing approaches often rely on static pre-defined priors, which limit their ability to adapt mask strategies dynamically for network optimization. In this paper, we focus on the learning process of the network and introduce human-like curriculum into MIM for dynamic representation refinement, and propose an end-to-end framework Curriculum Masked Image Modeling (CurMIM). CurMIM consists of two components: Mask Priority Measurer, which acts as a curriculum learner to determine mask priority values using the network's intrinsic state information, and Dual Adaptive Selector, which serves as a curriculum scheduler to create effective masks based on these values. With negligible extra parameters, our curriculum-based method consistently establishes noticeable improvements across varying model sizes and benchmarks, showing effectiveness and generalization. © 2025 IEEE.

关键词： Curriculum Learning Image Representation Masked Image Modeling Visual Pre-training

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HiRes: Hierarchical Feature Optimization and Rescorer for Automatic ICD Coding

HiRes: Hierarchical Feature Optimization and Rescorer for Au...

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2025 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2025

作者： Liang, Zhenpeng Guan, Hongjiao Lu, Wenpeng Peng, Xueping Xu, Bing Yang, Muyun Key Laboratory of Computing Power Network and Information Security Ministry of Education Shandong Computer Science Center National Supercomputer Center in Jinan Qilu University of Technology Shandong Academy of Sciences Jinan China Shandong Provincial Key Laboratory of Computing Power Internet and Service Computing Shandong Fundamental Research Center for Computer Science Jinan China Australian Artificial Intelligence Institute University of Technology Sydney Sydney Australia Faculty of Computing Harbin Institute of Technology Harbin China

ISBN: (纸本)9798350368741

The International Classification of Diseases (ICD) coding assigns standardized codes to diseases. Automating this process enhances the efficiency and accuracy of clinical records processing. However, current methods struggle with noisy and lengthy clinical texts, making it difficult to ensure the reliability of feature extraction. Furthermore, they typically make separate binary predictions for each code, overlooking the dependencies between them. To address these issues, we propose a novel model called Hierarchical Feature Optimization and Rescorer (HiRes). We employ a cascaded convolution architecture to mitigate noise and enhance feature representation. Additionally, a masked autoencoder-based rescorer is introduced to capture ICD code interdependencies, refining initial predictions for improved accuracy. The model also considers the inconsistencies in code representations. Experiments on the MIMIC datasets demonstrate the effectiveness of our model. © 2025 IEEE.

关键词： automatic ICD coding cascaded convolutional network multi-label classification

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Mirror Contrastive Loss Based Sliding Window Transformer for Subject-Independent Motor Imagery Based EEG Signal Recognition

Mirror Contrastive Loss Based Sliding Window Transformer for...

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4th International Workshop on Human Brain and Artificial Intelligence, HBAI 2024

作者： Luo, Jing Mao, Qi Shi, Weiwei Shi, Zhenghao Wang, Xiaofan Lu, Xiaofeng Hei, Xinhong Shaanxi Key Laboratory for Network Computing and Security Technology and Human–Machine Integration Intelligent Robot Shaanxi University Engineering Research Center School of Computer Science and Engineering Xi’an University of Technology Shaanxi Xi’an China

ISBN: (纸本)9789819640003

While deep learning models have been extensively utilized in motor imagery based EEG signal recognition, they often operate as black boxes. Motivated by neurological findings indicating that the mental imagery of left or right-hand movement induces event-related desynchronization (ERD) in the contralateral sensorimotor area of the brain, we propose a Mirror Contrastive Loss based Sliding Window Transformer (MCL-SWT) to enhance subject-independent motor imagery-based EEG signal recognition. Specifically, our proposed mirror contrastive loss enhances sensitivity to the spatial location of ERD by contrasting the original EEG signals with their mirror counterparts—mirror EEG signals generated by interchanging the channels of the left and right hemispheres of the EEG signals. Moreover, we introduce a temporal sliding window transformer that computes self-attention scores from high temporal resolution features, thereby improving model performance with manageable computational complexity. We evaluate the performance of MCL-SWT on subject-independent motor imagery EEG signal recognition tasks, and our experimental results demonstrate that MCL-SWT achieved accuracies of 66.48% and 75.62%, surpassing the state-of-the-art (SOTA) model by 2.82% and 2.17%, respectively. Furthermore, ablation experiments confirm the effectiveness of the proposed mirror contrastive loss. A code demo of MCL-SWT is available at https://***/roniusLuo/MCL_SWT. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Image enhancement

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Multi-label pathology editing of chest X-rays with a Controlled Diffusion Model

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Medical Image Analysis 2025年 103卷

作者： Chu, Huan Qi, Xiaolong Wang, Huiling Liang, Yi School of Network Security and Information Technology Yili Normal University Yining835000 China State Key Laboratory for Novel Software Technology Nanjing University Nanjing210023 China Key Laboratory of Intelligent Computing Research and Application Yining835399 China

Large-scale generative models have garnered significant attention in the field of medical imaging, particularly for image editing utilizing diffusion models. However, current research has predominantly concentrated on pathological editing involving single or a limited number of labels, making it challenging to achieve precise modifications. Inaccurate alterations may lead to substantial discrepancies between the generated and original images, thereby impacting the clinical applicability of these models. This paper presents a diffusion model with untangling capabilities applied to chest X-ray image editing, incorporating a mask-based mechanism for bone and organ information. We successfully perform multi-label pathological editing of chest X-ray images without compromising the integrity of the original thoracic structure. The proposed technology comprises a chest X-ray image classifier and an intricate organ mask;the classifier supplies essential feature labels that require untangling for the stabilized diffusion model, while the complex organ mask facilitates directed and controllable edits to chest X-rays. We assessed the outcomes of our proposed algorithm, named Chest X-rays_Mpe, using MS-SSIM and CLIP scores alongside qualitative evaluations conducted by radiology experts. The results indicate that our approach surpasses existing algorithms across both quantitative and qualitative metrics. © 2025

关键词： Medical imaging

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