Disrupting the circadian rhythms will cause health problems such as sleep disorders, memory disorders and obesity. Finding the suitable external stimulation to synchronize a model with a desired phase is a biologicall...
详细信息
ISBN:
(纸本)9781467374439
Disrupting the circadian rhythms will cause health problems such as sleep disorders, memory disorders and obesity. Finding the suitable external stimulation to synchronize a model with a desired phase is a biologically significant issue. The phase control of circadian rhythms for Drosophila is considered from control engineering viewpoint in this paper. If all parameters of the model are known, we can use the feedback linearization to design a tracking controller for the phase ***, in practice, parameters uncertainties always exist. To deal with this problem, a slide-mode controller is proposed for the phase tracking control of circadian rhythms. The simulation results show the effectiveness of the proposed method.
Architectural distortion is the third most common sign of breast cancer in mammograms. The accurate recognition is important for computer aided diagnosis of breast cancer. However, due to the subtle symptom and comple...
详细信息
ISBN:
(纸本)9781509037117
Architectural distortion is the third most common sign of breast cancer in mammograms. The accurate recognition is important for computer aided diagnosis of breast cancer. However, due to the subtle symptom and complex structures in the mammogram images, it is difficult to recognize whether a region of interest (ROI) is truly an architectural distortion. In this paper, we proposed a new method for architectural distortion recognition. In the proposed method, several texture features are extracted for each region of interest, including features from GLCM matrix, spiculated related features, entropy features, etc. Feature selection is obtained by a sub-classes clustering based multi-task learning method (SMTL), which can utilize the discriminative label information and reflect the multi-clustering characteristic of the data samples. Finally, the powerful sparse representation based classifier is used for the classification of AD or non-AD. The proposed method has been tested on DDSM dataset and compared with several other methods, the experimental results showed the effectiveness of the proposed method.
Mass localization is a crucial problem in computer-aided detection (CAD) system for the diagnosis of suspicious regions in mammograms. In this paper, a new automatic mass detection method for breast cancer in mammogra...
详细信息
Mass localization is a crucial problem in computer-aided detection (CAD) system for the diagnosis of suspicious regions in mammograms. In this paper, a new automatic mass detection method for breast cancer in mammographic images is proposed. Firstly, suspicious regions are located with an adaptive region growing method, named multiple concentric layers (MCL) approach. Prior knowledge is utilized by tuning parameters with training data set during the MCL step. Then, the initial regions are further refined with narrow band based active contour (NBAC), which can improve the segmentation accuracy of masses. Texture features and geometry features are extracted from the regions of interest (ROI) containing the segmented suspicious regions and the boundaries of the segmentation. The texture features are computed from gray level co-occurrence matrix (GLCM) and completed local binary pattern (CLBP). Finally, the ROIs are classified by means of support vector machine (SVM), with supervision provided by the radiologist׳s diagnosis. To deal with the imbalance problem regarding the number of non-masses and masses, supersampling and downsampling are incorporated. The method was evaluated on a dataset with 429 craniocaudal (CC) view images, containing 504 masses. Among them, 219 images containing 260 masses are used to optimize the parameters during MCL step, and are used to train SVM. The remaining 210 images (with 244 masses) are used to test the performance. Masses are detected with 82.4% sensitivity with 5.3 false positives per image (FPsI) with MCL, and after active contour refinement, feature analysis and classification, it obtained 1.48 FPsI at the sensitivity 78.2%. Testing on 164 normal mammographic images showed 5.18 FPsI with MCL and 1.51 FPsI after classification. Experiments on mediolateral oblique (MLO) images have also been performed, the proposed method achieved a sensitivity 75.6% at 1.38 FPsI. The method is also analyzed with free response operating characteristi
暂无评论