Acoustic loudspeaker measurements are an essential aspect in loudspeaker development and design. Established setups usually require acoustic measurement rooms or chambers where the speaker under test has to be install...
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Aims/Purpose: Alzheimer's disease (AD), the leading cause of dementia, affects millions, underscoring the need for early diagnostic methods. The retina, which can exhibit AD-related pathological processes, offers ...
Aims/Purpose: Alzheimer's disease (AD), the leading cause of dementia, affects millions, underscoring the need for early diagnostic methods. The retina, which can exhibit AD-related pathological processes, offers a promising diagnostic site. This study aims to utilize Hyperspectral Retinal Imaging (HSRI) to differentiate between positive (+) and negative (-) PET-amyloid beta (Aβ) status. Within this cohort, a subset is Aβ+ while remaining cognitively healthy, indicating preclinical amyloid accumulation. Unlike most research targeting later symptomatic stages, our approach could facilitate interventions before clinically apparent neurodegeneration occurs. Methods: Data was used from 37 Aβ- and 25 Aβ+ individuals of which 8 with mild cognitive impairment (MCI). HSRI were captured using an easy-to-use hyperspectral snapshot camera, covering a spectral range of 460–630 nm. Images were taken from primary, inferior, and superior views of the retina, with further regions of interest (ROI) defined in the primary view. After preprocessing, these spectra were used to train machine learning classifiers [1]. Results: The best classifier performance was observed using XGBoost with the superior spectra (AUC = 0.72), and using a Linear Discriminant Analysis classifier in superior quadrants (S1 AUC = 0.74, S2 AUC = 0.68). Lower performance in other ROI underscored the variability in amyloid deposition across the retina, correlating with previous findings that retinal Aβ deposits in AD patients are frequently concentrated in the superior quadrants. Conclusions: We were able to achieve similar performance of previous research in AD patients [1], but in a preclinical cohort of cognitively normal participants up to MCI patients. Consistent with the literature, the superior retinal regions seem most discriminative for Aβ status. Further exploration of the specificity of the HSRI signal will pave the way for early AD detection, potentially improving outcomes through earlier therapeutic i
Autonomous mobile robots (AMRs) face challenges in navigating complex environments efficiently. To manoeuvre through both narrow and wide spaces, AMRs require two essential design features: a compact form for tight ar...
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This paper addresses the classical problem of one-bit compressed sensing using a deep learning-based reconstruction algorithm that leverages a trained generative model to enhance the signal reconstruction performance....
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Complete coverage path planning (CCPP) is essential for autonomous cleaning robots, particularly in complex and variable environments where traditional, fixed-footprint designs may fall short. This paper presents adap...
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Radiotelescopes are typically composed of large reflector antennas located outdoors. These antennas are designed to achieve high levels of gain, which is possible due to their large size and RF systems designed for wo...
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In this paper we derive the a posteriori probability for the location of bursts of noise additively superimposed on a Gaussian AR process. The theory is developed to give a sequentially based restoration algorithm sui...
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In this paper we derive the a posteriori probability for the location of bursts of noise additively superimposed on a Gaussian AR process. The theory is developed to give a sequentially based restoration algorithm suitable for real-time applications. The algorithm is particularly appropriate for digital audio restoration, where clicks and scratches may be modelled as additive bursts of noise. Experiments are carried out on both real audio data and synthetic AR processes and significant improvements are demonstrated over existing restoration techniques.
When the FFT (or DCT or DST) is used for fast interpolation, errors arise due to the assumed periodicity in the data, and the resulting implied discontinuities of the function and its derivatives at the block edges. B...
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When the FFT (or DCT or DST) is used for fast interpolation, errors arise due to the assumed periodicity in the data, and the resulting implied discontinuities of the function and its derivatives at the block edges. By adding simple functions before interpolation and subtracting them again afterwards, these interpolation errors can be removed.
Nonlinear recursive (NLR) digital smoothing filters are introduced and their use for spectrum noise floor estimation described. NLR filters outperform linear filters, achieving comparable results to median filters. an...
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Nonlinear recursive (NLR) digital smoothing filters are introduced and their use for spectrum noise floor estimation described. NLR filters outperform linear filters, achieving comparable results to median filters. and are very simple to implement.
The purpose of this paper is to describe a noncoherent correlation technique for the formation of 3-D acoustic images, mainly for underwater applications. This technique is applied to the envelope of signals received ...
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The purpose of this paper is to describe a noncoherent correlation technique for the formation of 3-D acoustic images, mainly for underwater applications. This technique is applied to the envelope of signals received by a 2-D array. The performances of the technique are compared with those of the coherent technique of focused beamforming in terms of angular resolution, depth of field, beam pattern, and accuracy in range determination. Moreover, special attention is given to the modalities for an efficient implementation on a digital computer. The complete absence of grating lobes, for whatever arrangement of the transducers, and the much higher speed of the imaging process, as compared with that of beamforming in the time domain, are the two major advantages of this technique. A reduction in the speckle effect, the possibility of creating a virtual depth of field, the feasibility of using square-law transducers, and the implementation simplicity are additional interesting characteristics. The results of some simulations are reported and compared with those obtained by the beamforming process.
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