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Understanding metric-related pitfalls in image analysis validation

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arXiv 2023年

作者： Reinke, Annika Tizabi, Minu D. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Kavur, A. Emre Rädsch, Tim Sudre, Carole H. Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Buettner, Florian Cardoso, M. Jorge Cheplygina, Veronika Chen, Jianxu Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kleesiek, Jens Kofler, Florian Kooi, Thijs Kopp-Schneider, Annette Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Riegler, Michael A. Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. van Calster, Ben Varoquaux, Gaël Yaniv, Ziv R. Jäger, Paul F. Maier-Hein, Lena Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany NCT Heidelberg A Partnership Between DKFZ University Medical Center Heidelberg Germany Heidelberg Division of Medical Image Computing Germany Heidelberg Division of Intelligent Medical Systems Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montreal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Leuven Belgium partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany and Frankfurt Cancer Insititute Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for Statistics in Medicine University of Oxford Oxford United Kingdom Center for Biomedical In

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately. While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. While focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation. © 2023, CC BY.

关键词： Computer vision

Accurate Retinal Vessel Segmentation via Octave Convolution Neural Network

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arXiv 2019年

作者： Fan, Zhun Mo, Jiajie Qiu, Benzhang Li, Wenji Zhu, Guijie Li, Chong Hu, Jianye Rong, Yibiao Chen, Xinjian Department of Electrical and Information Engineering Shantou University Shantou515063 China Guangdong Provincial Key Laboratory of Digital Signal and Image Processing College of Engineering Shantou University Shantou515063 China School of Electrical and Information Engineering Soochow University Suzhou215006 China State Key Laboratory of Radiation Medicine and Protection Soochow University Suzhou215123 China

Retinal vessel segmentation is a crucial step in diagnosing and screening various diseases, including diabetes, ophthalmologic diseases, and cardiovascular diseases. In this paper, we propose an effective and efficient method for vessel segmentation in color fundus images using encoder-decoder based octave convolution network. Compared with other convolution networks utilizing vanilla convolution for feature extraction, the proposed method adopts octave convolution for learning multiplespatial-frequency features, thus can better capture retinal vasculatures with varying sizes and shapes. It is demonstrated that the feature maps of low-frequency kernels respond mainly to the major vascular tree, whereas the high-frequency feature maps can better capture the fine details of thin vessels. To provide the network the capability of learning how to decode multifrequency features, we extend octave convolution and propose a new operation named octave transposed convolution. A novel architecture of convolutional neural network is proposed based on the encoder-decoder architecture of UNet, which can generate high resolution vessel segmentation in one single forward feeding. The proposed method is evaluated on four publicly available datasets, including DRIVE, STARE, CHASE DB1, and HRF. Extensive experimental results demonstrate that the proposed approach achieves better or comparable performance to the stateof-the-art methods with fast processing speed. Copyright © 2019, The Authors. All rights reserved.

关键词： Convolution

Why is the Winner the Best?

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Why is the Winner the Best?

Conference on Computer Vision and Pattern Recognition (CVPR)

作者： M. Eisenmann A. Reinke V. Weru M. D. Tizabi F. Isensee T. J. Adler S. Ali V. Andrearczyk M. Aubreville U. Baid S. Bakas N. Balu S. Bano J. Bernal S. Bodenstedt A. Casella V. Cheplygina M. Daum M. De Bruijne A. Depeursinge R. Dorent J. Egger D. G. Ellis S. Engelhardt M. Ganz N. Ghatwary G. Girard P. Godau A. Gupta L. Hansen K. Harada M. Heinrich N. Heller A. Hering A. Huaulmé P. Jannin A. E. Kavur O. Kodym M. Kozubek J. Li H. Li J. Ma C. Martín-Isla B. Menze A. Noble V. Oreiller N. Padoy S. Pati K. Payette T. Rädsch J. Rafael-Patiño V. Singh Bawa S. Speidel C. H. Sudre K. Van Wijnen M. Wagner D. Wei A. Yamlahi M. H. Yap C. Yuan M. Zenk A. Zia D. Zimmerer D. Aydogan B. Bhattarai L. Bloch R. Brüngel J. Cho C. Choi Q. Dou I. Ezhov C. M. Friedrich C. Fuller R. R. Gaire A. Galdran Á. García Faura M. Grammatikopoulou S. Hong M. Jahanifar I. Jang A. Kadkhodamohammadi I. Kang F. Kofler S. Kondo H. Kuijf M. Li M. Luu T. Martinčič P. Morais M. A. Naser B. Oliveira D. Owen S. Pang J. Park S. Park S. Płotka E. Puybareau N. Rajpoot K. Ryu N. Saeed A. Shephard P. Shi D. Štepec R. Subedi G. Tochon H. R. Torres H. Urien J. L. Vilaça K. A. Wahid H. Wang J. Wang L. Wang X. Wang B. Wiestler M. Wodzinski F. Xia J. Xie Z. Xiong S. Yang Y. Yang Z. Zhao K. Maier-Hein P. F. Jäger A. Kopp-Schneider L. Maier-Hein Division of Intelligent Medical Systems German Cancer Research Center (DKFZ) Heidelberg Germany Helmholtz Imaging German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Engineering and Physical Sciences School of Computing University of Leeds Leeds UK Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA) University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology University of Washington Seattle WA USA Department of Computer Science Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) University College London London UK Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Division of Translational Surgical Oncology National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Department of Radiology and Nuc

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and post-processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

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Experimental observation of real spectra in Parity-Time symmetric ZRC dimers with positive and negative frequencies

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arXiv 2020年

作者： Tabeu, Stéphane Boris Fotsa-Ngaffo, Fernande Tagouegni, Senghor Shouno, Kazuhiro Kenfack-Jiotsa, Aurélien Laboratory of Mechanics Materials and Structures Department of Physics Faculty of Science University of Yaounde I P.O. Box 812 Yaounde Cameroon Nonlinear Physics and Complex Systems Group Department of Physics Higher Teacher’s Training College University of Yaounde I P.O. Box 47 Yaounde Cameroon Laboratory of Electronics and Signal Processing Department of Electrical and Telecommunication Engineering National Advanced School of Engineering University of Yaounde I P.O. Box 8390 Yaounde Cameroon Institute of Wood technologies University of Yaounde I P.O. Box 306 Mbalmayo Cameroon Graduate School of Systems and Information Engineering University of Tsukuba Ibaraki305-8573 Japan P.O. Box 105 Yaounde Cameroon

We present in this work the first experimental observation of oscillations in Parity-Time symmetric ZRC dimers. The system obtained is of first order ordinary differential equation due to the use of imaginary resistors. The coupled cells must share the same type of frequency: positive or negative. We observed the real and imaginary parts of the voltage across the components of a ZRC cell. Exceptional points are well identified. This work may be very useful in the generation of new type of oscillators. It can also be used in the design of new optoelectronic devices for major applications in the transport of information and the mimics of two-level systems for quantum computing. Copyright © 2020, The Authors. All rights reserved.

关键词： Resistors

Granular Computing: An Augmented Scheme of Degranulation Through a Modified Partition Matrix

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arXiv 2020年

作者： Xu, Kaijie Pedrycz, Witold Li, Zhiwu Xing, Mengdao School of Electro-Mechanical Engineering Xidian University Xi’an710071 China Department of remote sensing science and technology School of Electronic Engineering Xidian University Xi’an710071 China Department of Electrical and Computer Engineering University of Alberta EdmontonABT6R 2V4 Canada Systems Research Institute Polish Academy of Sciences Warsaw Poland Faculty of Engineering King Abdulaziz University Jeddah21589 Saudi Arabia Institute of Systems Engineering Macau University of Science and Technology Macau999078 China National Laboratory of Radar Signal Processing Xidian University Xi’an710071 China Collaborative Innovation Center of Information Sensing and Understanding Xidian University Xi’an710071 China National Key Laboratory of Microwave Imaging Technology Institute of Electronics Chinese Academy of Sciences Beijing100190 China

As an important technology in artificial intelligence Granular Computing (GrC) has emerged as a new multi-disciplinary paradigm and received much attention in recent years. Information granules forming an abstract and efficient characterization of large volumes of numeric data have been considered as the fundamental constructs of GrC. By generating centroids (prototypes) and partition matrix, fuzzy clustering is a commonly encountered way of information granulation. As a reverse process of granulation, degranulation involves data reconstruction completed on a basis of the granular representatives (decoding information granules into numeric data). Previous studies have shown that there is a relationship between the reconstruction error and the performance of the granulation process. Typically, the lower the degranulation error is, the better performance of granulation process becomes. However, the existing methods of degranulation usually cannot restore the original numeric data, which is one of the important reasons behind the occurrence of the reconstruction error. To enhance the quality of reconstruction (degranulation), in this study, we develop an augmented scheme through modifying the partition matrix. By proposing the augmented scheme, we dwell on a novel collection of granulation-degranulation mechanisms. In the constructed approach, the prototypes can be expressed as the product of the dataset matrix and the partition matrix. Then, in the degranulation process, the reconstructed numeric data can be decomposed into the product of the partition matrix and the matrix of prototypes. Both the granulation and degranulation are regarded as generalized rotation between the data subspace and the prototype subspace with the partition matrix and the fuzzification factor. By modifying the partition matrix, the new partition matrix is constructed through a series of matrix operations. We offer a thorough analysis of the developed scheme. Copyright © 2020, The Authors. Al

关键词： Granulation

Tunable superconducting josephson dielectric metamaterial

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arXiv 2019年

作者： Trepanier, M. Zhang, Daimeng Filippenko, L.V. Koshelets, V.P. Anlage, Steven M. Center for Nanophysics and Advanced Materials Department of Physics University of Maryland College ParkMD20742-4111 United States Department of Electrical and Computer Engineering University of Maryland College ParkMD20742-3285 United States Laboratory of Superconducting Devices for Signal Detection and Processing Kotelnikov Institute of Radio Engineering and Electronics Moscow125009 Russia

We demonstrate a low-dissipation dielectric metamaterial with tunable properties based on the Josephson effect. Superconducting wires loaded with regularly spaced Josephson junctions (critical current Ic ≈ 0.25 µA) spanning a K-band waveguide and aligned with the microwave electric fields create a superconducting dielectric metamaterial. Applied dc current tunes the cutoff frequency and effective permittivity of this unique electric metamaterial. The results are in agreement with an analytical model for microwave transmission through the artificial dielectric medium. Copyright © 2019, The Authors. All rights reserved.

关键词： Metamaterials

Metrics Reloaded: Recommendations for image analysis validation

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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

Quality Inspection of Phalaenopsis Hybrids Using Hyperspectral Band Selection Techniques

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Quality Inspection of Phalaenopsis Hybrids Using Hyperspectr...

IEEE International Symposium on Geoscience and Remote Sensing (IGARSS)

作者： Yen-Chieh Ouyang Bo-Han Chen Meng-Chueh Lee Tsang-Sen Liu Mang Ou-Yang Hsian-Min Chen Chao-Cheng Wu Chia-Hsien Wen Min-Shao Shih Chein-I Chang Yung-Jhe Yan Department of Electrical Engineering National Chung Hsing University Taiwan Institute of communication Engineering National Chung Hsing University Taiwan Taiwan Agriculture Research Institute Nantou Taiwan Department of Electrical and Computer Engineering National Chiao-Tung University Hsinchu City Taiwan Center for Quantitative Imaging in Medicine Taichung Veterans General Hospital Taiwan Department of Electrical Engineering National Taipei University of Technology Taipei Taiwan Department of Computer Science and Information Management Providence University Taiwan Remote Sensing Signal and Image Processing Laboratory University of Maryland Baltimore MD USA

Fusarium wilt on Phalaenopsis is a disease that makes farmers suffer seriously. Although Phalaenopsis does not die immediately with Fusarium wilt, it seriously decreases the quality that buyers cannot accept. In this paper, we introduce an emerging method to detect Fusarium wilt at the base of Phalaenopsis stems. The detection model divides Phalaenopsis samples into two categories, healthy and infection. The band selection (BS) processing technique based on band prioritization (BP) is applied to extract significant bands and eliminate redundant bands. Subsequently, some algorithms which are constrained energy minimization (CEM), spectral information divergence(SID) and SeQuential N-FINDER to detect the Fusarium wilt, and we hope the research would help farmers decrease their losses.

关键词： Hyperspectral imaging Support vector machines Diseases signal to noise ratio Hybrid fiber coaxial cables Correlation

AIM 2019 challenge on real-world image super-resolution: Methods and results

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arXiv 2019年

作者： Lugmayr, Andreas Danelljan, Martin Timofte, Radu Fritsche, Manuel Gu, Shuhang Purohit, Kuldeep Kandula, Praveen Suin, Maitreya Rajagopalan, A.N. Joon, Nam Hyung Won, Yu Seung Kim, Guisik Kwon, Dokyeong Hsu, Chih-Chung Lin, Chia-Hsiang Huang, Yuanfei Sun, Xiaopeng Lu, Wen Li, Jie Gao, Xinbo Bell-Kligler, Sefi Computer Vision Lab ETH Zurich Indian Institute Of Technology Madras India Image Communication & Signal Processing Laboratory Hanyang University Seoul Korea Republic of CVML Chung-Ang University Department Management Information Systems National Pingtung University of Science and Technology Department of Electrical Engineering National Cheng-Kung University Xidian University Weizmann Institute of Science Israel

This paper reviews the AIM 2019 challenge on real world super-resolution. It focuses on the participating methods and final results. The challenge addresses the real world setting, where paired true high and low-resolution images are unavailable. For training, only one set of source input images is therefore provided in the challenge. In Track 1: Source Domain the aim is to super-resolve such images while preserving the low level image characteristics of the source input domain. In Track 2: Target Domain a set of high-quality images is also provided for training, that defines the output domain and desired quality of the superresolved images. To allow for quantitative evaluation, the source input images in both tracks are constructed using artificial, but realistic, image degradations. The challenge is the first of its kind, aiming to advance the state-of-the-art and provide a standard benchmark for this newly emerging task. In total 7 teams competed in the final testing phase, demonstrating new and innovative solutions to the problem. Copyright © 2019, The Authors. All rights reserved.

关键词： Optical resolving power