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arXiv 2025年

作者： Li, Bo Zhang, Bob Zhang, Chengyang Zhou, Minghao Huang, Weiliang Wang, Shihang Wang, Qing Li, Mengran Zhang, Yong Song, Qianqian PAMI Research Group Department of Computer and Information Science University of Macau Taipa China Beijing Key Laboratory of Multimedia and Intelligent Software Technology Beijing Institute of Artificial Intelligence Beijing University of Technology Beijing China Department of Health Outcomes and Biomedical Informatics College of Medicine University of Florida Florida United States Faculty of Applied Sciences Macao Polytechnic University Taipa China School of Intelligent Systems Engineering Sun Yat-sen University Guangdong China Department of Cancer Biology Wake Forest School of Medicine Winston SalemNC United States

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. This process involves transforming high-throughput cellular images into quantitative representations for downstream analysis. However, existing methods require computationally extensive and complex multi-step procedures, which can introduce inefficiencies, limit generalizability, and increase potential errors. To address these challenges, we present PhenoProfiler, an innovative model designed to efficiently and effectively extract morphological representations, enabling the elucidation of phenotypic changes induced by treatments. PhenoProfiler is designed as an end-to-end tool that processes whole-slide multi-channel images directly into low-dimensional quantitative representations, eliminating the extensive computational steps required by existing methods. It also includes a multi-objective learning module to enhance robustness, accuracy, and generalization in morphological representation learning. PhenoProfiler is rigorously evaluated on large-scale publicly available datasets, including over 230,000 whole-slide multi-channel images in end-to-end scenarios and more than 8.42 million single-cell images in non-end-to-end settings. Across these benchmarks, PhenoProfiler consistently outperforms state-of-the-art methods by up to 20%, demonstrating substantial improvements in both accuracy and robustness. Furthermore, PhenoProfiler uses a tailored phenotype correction strategy to emphasize relative phenotypic changes under treatments, facilitating the detection of biologically meaningful signals. UMAP visualizations of treatment profiles demonstrate PhenoProfiler’s ability to effectively cluster treatments with similar biological annotations, thereby enhancing interpretability. These findings establish PhenoProfiler as a scalable, generalizable, and robust tool for phenotypic learning, offering transformative advancement

关键词： Benchmarking

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A deep reinforcement learning approach for wind speed forecasting

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engineering Applications of Computational Fluid Mechanics 2025年第1期19卷

作者： Band, Shahab S. Lin, Ting Jia Qasem, Sultan Noman Ameri, Rasoul Shahmirzadi, Danyal Aslam, Muhammad Shamrooz Pai, Hao-Ting Salwana, Ely Mousavi, Amir International Graduate School of AI National Yunlin University of Science and Technology Douliu Taiwan Department of Information Management International Graduate School of Artificial Intelligence National Yunlin University of Science and Technology Douliu Taiwan Computer Science Department College of Computer and Information Sciences Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh Saudi Arabia Computer Science Department Faculty of Applied Science Taiz University Taiz Yemen Department of Information Management National Yunlin University of Science and Technology Douliu Taiwan Graduate School of Engineering Science and Technology National Yunlin University of Science and Technology Douliu Taiwan Artificial Intelligence Research Institute China University of Mining and Technology Xuzhou China Department of Big Data Business Analytics National Pingtung University Pingtung Taiwan Institute of Visual Informatics Universiti Kebangsaan Malaysia Selangor Bangi Malaysia Institute of the Information Society Ludovika University of Public Service Budapest Hungary John Von Neumann Faculty of Informatics Obuda University Budapest Hungary Department of Information and Computing Systems Abylkas Saginov Karaganda Technical University Karaganda Kazakhstan

The conventional wind forecasting methods often struggle to handle the non-stationary and inconsistent wind patterns. This paper presents a hybrid method of Empirical Wavelet Transf... 详细信息

The conventional wind forecasting methods often struggle to handle the non-stationary and inconsistent wind patterns. This paper presents a hybrid method of Empirical Wavelet Transform (EWT) and Deep Reinforcement Learning (DRL) for wind speed modeling to overcome the forecasting challenges. The EWT method transforms the original wind speed series into several independent modes and a residual series. In addition, the DRL method is utilised to optimise the weights associated with three distinct supervised deep learning models, i.e., Long Short-Term Memory (LSTM), Convolutional Neural Networks with LSTM (CNN-LSTM), and CNN with Gated Recurrent Units (CNN-GRU). The performance of the proposed EWT-DRL is evaluated against deep learning models, including LSTM, CNN-LSTM, CNN-GRU, and their coupling with EWT. The combination of EWT and the DRL (EWT-DRL) method achieves a Mean Absolute Error (MAE) of 0.151, a Mean Squared Error (MSE) of 0.060, a Root Mean Squared Error (RMSE) of 0.192, and a correlation coefficient (R) of 0.9913. These results indicate the effectiveness of EWT-DRL in improving accuracy for wind speed modeling. © 2025 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

关键词： artificial intelligence deep reinforcement learning empirical wavelet transform long short-term memory machine learning Renewable energy wind speed forecasting

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Application Aspects of Active-set Quadratic Programming in Real-time Embedded Model Predictive Vibration Control

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IFAC-PapersOnLine 2017年第1期50卷 11625-11631页

作者： Batista G. Takács G. Rohal’-Ilkiv B. Institute of Automation Measurement and Applied Informatics Faculty of Mechanical Engineering Slovak University of Technology in Bratislava Slovakia

This paper presents a study on the practical utilization of various microcontroller units (MCU) for model predictive vibration control, using an online active-set quadratic programming solver. The implementation properties of various 32bit MCUs are assessed in experiment. An analysis of memory requirements is made on all investigated MCUs, along with evaluating timing requirements for a simple vibration control problem. These tests show execution time limits, memory footprint, and convergence under different circumstances. The experiments investigate the effects of hot-starting, numerical precision and the use of the floating-point unit (FPU) of the MCU. The results presented in this paper show that the hot-starting technique used with double precision data format is preferable, since computation using single precision numeric format fails to converge on many instances. Although it is tempting to reduce numerical precision to extend the maximal horizon stored in the volatile and nonvolatile memories and to cut execution times, the numerical stability of the investigated online active-set quadratic programming solver is heavily affected. Moreover, it has been found that a built-in FPU does not have significant impact on performance; the presence of this hardware feature does not significantly aid the implementation of model predictive control for the case study presented here. © 2017

关键词： embedded systems microcontroller unit model predictive control online active-set strategy quadratic programming vibration control

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Blockchain-Assisted Secure Fine-Grained Searchable Encryption for a Cloud-Based Healthcare Cyber-Physical System

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IEEE/CAA Journal of Automatica Sinica 2021年第12期8卷 1877-1890页

作者： Mamta Brij B.Gupta Kuan-Ching Li Victor C.M.Leun Kostas E.Psannis Shingo Yamaguchi IEEE the Department of Computer Engineering National Institute of Technology the Asia University the Macquarie University the Department of Computer Science and Information Engineering Providence University the Computer Science and Software Engineering Shenzhen University the University of British Columbia the Department of Applied Informatics University of Macedonia the Graduate School of Sciences and Technology for Innovation Yamaguchi University

The concept of sharing of personal health data over cloud storage in a healthcare-cyber physical system has become popular in recent times as it improves access *** privacy of health data can only be preserved by keeping it in an encrypted form,but it affects usability and flexibility in terms of effective ***-based searchable encryption(ABSE)has proven its worth by providing fine-grained searching capabilities in the shared cloud ***,it is not practical to apply this scheme to the devices with limited resources and storage capacity because a typical ABSE involves serious *** a healthcare cloud-based cyber-physical system(CCPS),the data is often collected by resource-constraint devices;therefore,here also,we cannot directly apply ABSE *** the proposed work,the inherent computational cost of the ABSE scheme is managed by executing the computationally intensive tasks of a typical ABSE scheme on the blockchain ***,it makes the proposed scheme suitable for online storage and retrieval of personal health data in a typical *** the assistance of blockchain technology,the proposed scheme offers two main ***,it is free from a trusted authority,which makes it genuinely decentralized and free from a single point of ***,it is computationally efficient because the computational load is now distributed among the consensus nodes in the blockchain ***,the task of initializing the system,which is considered the most computationally intensive,and the task of partial search token generation,which is considered as the most frequent operation,is now the responsibility of the consensus *** eliminates the need of the trusted authority and reduces the burden of data users,***,in comparison to existing decentralized fine-grained searchable encryption schemes,the proposed scheme has achieved a significant reduction in storage and computational cost for the secret

关键词： Cloud-based cyber-physical systems(CCPS) data encryption healthcare information search and retrieval keyword search public-key cryptosystems searchable encryption

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Roadmap on Neuromorphic Photonics

arXiv

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arXiv 2025年

作者： Brunner, Daniel Shastri, Bhavin J. Al-Qadasi, Mohammed A. Ballani, H. Barbay, Sylvain Biasi, Stefano Bienstman, Peter Bilodeau, Simon Bogaerts, Wim Böhm, Fabian Brennan, G. Buckley, Sonia Cai, Xinlun Strinati, Marcello Calvanese Canakci, B. Charbonnier, Benoit Chemnitz, Mario Chen, Yitong Cheung, Stanley Chiles, Jeff Choi, Suyeon Christodoulides, Demetrios N. Chrostowski, Lukas Chu, J. Clegg, J.H. Cletheroe, D. Conti, Claudio Dai, Qionghai Di Lauro, Luigi Diamantopoulos, Nikolaos-Panteleimon Dinc, Niyazi Ulas Ewaniuk, Jacob Fan, Shanhui Fang, Lu Franchi, Riccardo Freire, Pedro Gentilini, Silvia Gigan, Sylvain Giorgi, Gian Luca Gkantsidis, C. Gladrow, J. Goi, Elena Goldmann, M. Grabulosa, A. Gu, Min Guo, Xianxin Hejda, Matěj Horst, F. Hsieh, Jih-Liang Hu, Jianqi Hu, Juejun Huang, Chaoran Hurtado, Antonio Jaurigue, Lina Kalinin, K.P. Kamalian-Kopae, Morteza Kelly, D.J. Khajavikhan, Mercedeh Kremer, H. Laydevant, Jeremie Lederman, Joshua C. Lee, Jongheon Lenstra, Daan Li, Gordon H.Y. Li, Mo Li, Yuhang Lin, Xing Lin, Zhongjin Lis, Mieszko Lüdge, Kathy Lugnan, Alessio Lupo, Alessandro Lvovsky, A.I. Manuylovich, Egor Marandi, Alireza Marchesin, Federico Massar, Serge McCaughan, Adam N. McMahon, Peter L. Moralis-Pegios, Miltiadis Morandotti, Roberto Moser, Christophe Moss, David J. Mukherjee, Avilash Nikdast, Mahdi Offrein, B.J. Oguz, Ilker Oripov, Bakhrom O'Shea, G. Ozcan, Aydogan Parmigiani, F. Pasricha, Sudeep Pavanello, Fabio Pavesi, Lorenzo Peserico, Nicola Pickup, L. Pierangeli, Davide Pleros, Nikos Porte, Xavier Primavera, Bryce A. Prucnal, Paul Psaltis, Demetri Puts, Lukas Qiao, Fei Rahmani, B. Raineri, Fabrice Ríos Ocampo, Carlos A. Robertson, Joshua Romeira, Bruno Roques-Carmes, Charles Rotenberg, Nir Rowstron, A. Schoenhardt, Steffen Schwartz, Russell L.T. Shainline, Jeffrey M. Shekhar, Sudip Skalli, A. Sohoni, Mandar M. Sorger, Volker J. Soriano, Miguel C. Spall, James Stabile, Ripalta Stiller, Birgit Sunada, Satoshi Tefas, Anastasios Tossoun, Bassem Tsakyridis, Apostolos Turitsyn, Sergei K. Van der Sande, G Université Marie et Louis Pasteur CNRS UMR 6174 Institut FEMTO-ST Besançon25000 France Centre for Nanophotonics Department of Physics Engineering Physics & Astronomy Queen's University Canada Department of Electrical and Computer Engineering The University of British Columbia Vancouver Canada Microsoft Research Cambridge United Kingdom Université Paris-Saclay CNRS Centre de Nanosciences et de Nanotechnologies France Nanoscience Laboratory Department of Physics University of Trento Italy Photonics Research Group Department of Information Technology Ghent University imec Belgium Princeton University NJ United States Hewlett Packard Labs Hewlett Packard Enterprise Böblingen Germany National Institute of Standards and Technology BoulderCO United States State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information Technology Sun Yat-sen University China Enrico Fermi Research Center Rome Italy Université Grenoble-Alpes CEA Leti Grenoble France Leibniz-Institute of Photonic Technology Jena Germany Institute of Applied Optics and Biophysics Jena Germany Department of Automation Tsinghua University Beijing China Department of Electrical and Computer Engineering North Carolina State University NC United States Department of Electrical Engineering Stanford University CA United States University of Southern California Los AngelesCA United States Department of Physics Sapienza University Rome Italy Institute for Complex Systems National Research Council Rome Italy Varennes Canada NTT Device Technology Labs NTT Corporation Kanagawa Atsugi Japan Institute of Electrical and Microengineering School of Engineering École Polytechnique Fédérale de Lausanne Switzerland Edward L. Ginzton Laboratory Stanford University StanfordCA United States Department of Electronic Engineering Tsinghua University China Beijing National Research Center for Information Science and Technology Tsinghua University China Aston Univ

Neuromorphic photonics are processors inspired by the human brain and enabled by light (photons) instead of traditional electronics. Neuromorphic photonics and its associated concepts are experiencing a significant resurgence, building on foundational research from the 1980s and 1990s. This renewed momentum is driven by breakthroughs in photonic integration, nonlinear optics, and advanced materials, alongside the growing necessity of neuro-inspired computing in numerous applications of economic and societal relevance. The increasing demand for energy-efficient artificial intelligence (AI) solutions underscores the need for innovation and a cohesive vision to address key challenges, including scalability, energy efficiency, precision, and standardized performance benchmarks. Together, these efforts present an opportunity to establish a unique photonic advantage with practical, real-world applications. This roadmap consolidates recent advances while exploring emerging applications, reflecting the remarkable diversity of hardware platforms, neuromorphic concepts, and implementation philosophies reported in the field. It emphasizes the critical role of cross-disciplinary collaboration in this rapidly evolving field. The roadmap introduces various approaches to embedding the high-complexity transformations central to neuromorphic computing, focusing on frequency, delay, and spectral embeddings. This is followed by a discussion of architectures of photonic neural networks (PNNs) and an in-depth analysis of methods for implementing these architectures in photonic hardware. Dedicated sections delve into integrated photonic hardware, the realization of photonic weights and memories, and the optimization of training processes for photonic neuromorphic architectures. The roadmap concludes by exploring numerous potential applications, highlighting the challenges and advances necessary to transition neuromorphic photonic computing from a primarily academic pursuit to a technolog

关键词： Philosophical aspects

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DieT Transformer model with PCA-ADE integration for advanced multi-class brain tumor classification

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Intelligence-Based Medicine 2025年 11卷 100192-100192页

作者： Amin, Mohammad Nahar, Khalid M.O. Gharaibeh, Hasan Nasayreh, Ahmad Alsalmanc, Neda'a Alomar, Alaa Malkawi, Majd Alqasem, Noor Smerat, Aseel Zitar, Raed Abu Nusier, Shawd Ezugwu, Absalom E. Abualigah, Laith Department of Information Technology and Computer Sciences Yarmouk University Irbid 211633 Jordan Faculty of Computer Studies Arab Open University P.O.Box 84901 Riyadh 11681 Saudi Arabia Department of Computer Science Faculty of Information Technology Jordan University of Science and Technology Irbid 22110 Jordan Department of Medicine Faculty of Medicine Jordan University of Science and Technology Irbid 22110 Jordan Department of Biomedical Systems and Informatics Engineering Hijjawi Faculty for Engineering Technology Yarmouk University Irbid 21163 Jordan Centre for Research Impact & Outcome Chitkara University Institute of Engineering and Technology Chitkara University Punjab Rajpura 140401 India Department of Biosciences Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences Chennai 602105 India Artificial Intelligence and Sensing Technologies (AIST) Research Center University of Tabuk Tabuk 71491 Saudi Arabia Faculty of Engineering and Computing Liwa College Abu Dhabi United Arab Emirates Department of Health and Clinical Outcomes Research Saint Louis University St. Louis MO United States Unit for Data Science and Computing North-West University 11 Hofman Street Potchefstroom 2520 South Africa Computer Science Department Al al-Bayt University Mafraq 25113 Jordan Hourani Center for Applied Scientific Research Al-Ahliyya Amman University Amman 19328 Jordan

Early and accurate diagnosis of brain tumors is crucial to improving patient outcomes and optimizing treatment strategies. Long-term brain injury results from aberrant proliferation of either malignant or nonmalignant tissues in the brain. MRIs, or magnetic resonance imaging, are one of the most used approaches for detecting brain tumors. Professionals physically evaluate people after they have had MRI filtering, the process of enhancing MRI scans for radiologist interpretation, to establish if they have a brain tumor. Because different specialists use different frames to make judgments on the same MRI image, their analyses may yield contradictory results. Furthermore, simply detecting a tumor is insufficient. Inconsistent diagnoses can lead to delays in treatment, impacting survival rates and quality of care. It is also crucial to diagnose the patient's tumor so that treatment can begin as soon as possible. In this research, we investigate the multi-class classification of brain tumors utilizing a cutting-edge methodology that includes feature extraction from pictures using the DieT Transformer model, dimensionality reduction with PCA, and feature selection using the ADE algorithm. The proposed model, known in the publication as ADE_DieT, obtained an accuracy of 96.09 %. In addition, this article analyzes the performance of various pre-trained models, including MobileNetV3, NasNet, ResNet50, VGG16, VGG19, and DeiT. The proposed approach shortens the time required for manual diagnosis by clinicians by assisting in the rapid and accurate identification of brain tumors using MRI data. In oncology, this is important since it allows for early treatment. Integrating ADE_DieT into clinical workflows can support radiologists by reducing diagnosis time and enhancing diagnostic consistency. © 2024 The Authors

关键词： Brain tumor Medical image analysis MRI Vision Transformer

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Chaos and proportional integral derivative (PID) control on cancer dynamics with fractal fractional operator

Results in Engineering

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Results in engineering 2025年 26卷

作者： Farman, Muhammad Nisar, Kottakkaran Sooppy Jamil, Khadija Akgül, Ali Sambas, Aceng Bayram, Mustafa Habib, Mustafa Hassani, Murad Khan Faculty of Arts and Science Department of Mathematics Near East University Nicosia99138 Cyprus Faculty of Informatics and Computing Universiti Sultan Zainal Abidin Campus Besut Terengganu 22200 Malaysia Research Center of Applied Mathematics Khazar University Baku1096 Azerbaijan Department of Mathematics College of Science and Humanities in Alkharj Prince Sattam Bin Abdulaziz University Alkharj11942 Saudi Arabia Institute of Mathematics Khwaja Fareed University of Engineering and Information Technology Rahim Yar Khan Pakistan Department of Electronics and Communication Engineering Saveetha School of Engineering SIMATS Tamilnadu Chennai India Siirt University Art and Science Faculty Department of Mathematics Siirt56100 Turkey Department of Computer Engineering Biruni University Topkapi Istanbul34010 Turkey Near East University Mathematics Research Center Department of Mathematics Near East Boulevard Nicosia/Mersin 10 PC: 99138 Turkey Department of Mechanical Engineering Universitas Muhammadiyah Tasikmalaya Tamansari Gobras Tasikmalaya46196 Indonesia Department of Mathematics University of Engineering and Technology Lahore Pakistan Ghazni University Department of Mathematics Afghanistan Applied Science Research Center Applied Science Private University Amman11937 Jordan

This study presents a cancer dynamics model incorporating a fractal-fractional operator with a Mittag-Leffler kernel to capture complex interactions among cancer cells, tumor suppressor cells, immune cells, and oncolytic viruses. The model aims to enhance understanding of tumor-immune dynamics and improve treatment strategies. The existence and uniqueness of the solution are established using fixed point theory under the Lipschitz condition. Lyapunov stability of the system is also analyzed in the context of the fractal-fractional operator. To address chaotic behavior in cancer progression, chaos and Proportional-Integral-Derivative (PID) control techniques are implemented. These control methods effectively stabilize the system and regulate treatment administration. Numerical simulations illustrate the influence of fractional-order derivatives on tumor suppression and immune response, confirming the model's effectiveness in reflecting real-world cancer dynamics. © 2025 The Author(s)

关键词： Fractals

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Simulation and Control of a Continuously Cast Steel Billet in an Induction Furnace∗ 9

Simulation and Control of a Continuously Cast Steel Billet i...

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9th International Conference on Control, Decision and Information Technologies, CoDIT 2023

作者： Zarghoon, Sohaibullah Bartalsky, Lukas Belavy, Cyril Institute of Automation Measurement and Applied Informatics Slovak University of Technology Faculty of Mechanical Engineering Bratislava Slovakia

ISBN: (纸本)9798350311402

This paper presents a solution to a problem that Khan Steel Company in Afghanistan encountered in their induction furnace. The motivation for deploying induction heating technology in the industry is outlined, including a description of the current situation. Basic approaches for managing this technology, critical to the industry's success, are also provided. The process of creating an induction heating model using the COMSOL Multiphysics environment is described, with emphasis placed on the importance of starting the machine and determining the system's dynamics once it is in production mode. Finally, an identification and control proposal based on the distributed parameter system is presented, followed by a demonstration of the proposed control system using simulation results. © 2023 IEEE.

关键词： Induction heating

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Tracking of non-stationary biological signals with utilizing of adaptive filtering method 20

Tracking of non-stationary biological signals with utilizing...

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20th International Conference on Process Control, PC 2015

作者： Honek, Marek Malinovský, Ľudovít Ondrejkovič, Karol Rohaľ-Ilkiv, Boris Institute of Automation Measurement and Applied Informatics Faculty of Mechanical Engineering Slovak University of Technology Bratislava Slovakia

ISBN: (纸本)9781467366274

This paper presents an approach intended for tracking of biological non-stationary signals. The proposed approach utilizes a Kalman filter autoregressive model together with a method for estimation of covariance matrices of the uncorrelated process noise and measurement noise. The method was tested in simulations, where the ability of tracking of a class of time varying autoregressive processes was the subject of our interest. The obtained results are promising in the meaning that the suggested algorithm is suitable to track the time varying autoregressive processes with sufficient accuracy. © 2015 IEEE.

关键词： Adaptive filtering

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Moving Horizon Estimation for Integrated Navigation Filtering

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IFAC-PapersOnLine 2015年第23期48卷 519-526页

作者： Polóni, Tomá Rohal-Ilkiv, Boris Arne Johansen, Tor Department of Aerospace Engineering University of Michigan Ann Arbor United States Institute of Automation Measurement and Applied Informatics Faculty of Mechanical Engineering Slovak University of Technology Bratislava Slovakia Department of Engineering Cybernetics Norwegian University of Science and Technology Trondheim Norway

This paper presents a nonlinear numerical observer for accurate position, velocity and attitude (PVA) estimation including the accelerometer bias and gyro bias estimation. The Moving Horizon Observer (MHO) processes the accelerometer, gyroscope and magnetometer measurements from the Inertial Measurement Unit (IMU) and the position and velocity measurements from the Global Navigation Satellite System (GNSS). The nonlinear measurement equations with the rotation matrix, expressed through the quaternion parametrization, in combination with the state-space rigid body kinematic model of translational and rotational motion is the subject of optimization defined on a receding data window. The gradient-based trust-region method is applied to solve the MHO's nonlinear least-squares criterion. The MHO is tesed off-line in the numerical experiment involving the experimental flight data from a light fixed-wing aircraft. This study demonstrates the quality of the MHO computations with the comparison of the reference filter, the multiplicative Extended Kalman Filter (EKF). © 2015, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.

关键词： Nonlinear analysis Accelerometers Extended Kalman filters Fixed wings Global positioning system Gyroscopes Inertial navigation systems Kinematics Least squares approximations Nonlinear equations State estimation Attitude estimation Global Navigation Satellite Systems Inertial Measurement Unit (IMU) Moving horizon estimation Moving horizon observers Multiplicative extended kalman filters Non linear least squares Position estimation

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