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Transcranial direct current stimulation inhibits epileptic activity propagation in a large-scale brain network model

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science China(Technological sciences) 2023年第12期66卷 3628-3638页

作者： YU Ying FAN YuBo HAN Fang LUAN GuoMing WANG QingYun School of Engineering Medicine Beihang UniversityBeijing 100191China Beihang University Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringKey Laboratory Biomechanics&MechanobiologyMinistry of EducationBeijing 100191China College of Information Science and Technology Donghua UniversityShanghai 201620China Beijing Key Laboratory of Epilepsy Sanbo Brain HospitalCapital Medical UniversityBeijing 100069China Department of Dynamics and Control Beihang UniversityBeijing 100191China Beijing Institute of Brain Disorders Capital Medical UniversityBeijing 100069China

Transcranial direct current stimulation(tDCS)is a noninvasive technique that uses constant,low-intensity direct current to regulate brain *** studies have shown that cathode-tDCS(c-tDCS)is effective in reducing seizure frequency in patients with *** to the heterogeneity and patient specificity of seizures,patient-specific epilepsy networks are increasingly important in exploring the regulatory role of *** this study,we first set the left hippocampus,parahippocampus,and amygdala as the epileptogenic zone(EZ),and the left inferior temporal cortex and ventral temporal cortex as the initial propagation zone(PZ)to establish a large-scale epilepsy network *** we set tDCS cathode locations according to the maximum average energy of the simulated EEG signals and systematically study c-tDCS inhibitory effects on the propagation of epileptic *** results show that c-tDCS is effective in suppressing the propagation of epileptic ***,to consider the patient specificity,we set specific EZ and PZ according to the clinical diagnosis of 6 patients and establish patient-specific epileptic *** find that c-tDCS can suppress the propagation of abnormal activity in most patient-specific epileptic ***,when the PZ is widely distributed in both hemispheres,the treatment effect of c-tDCS is not ***,we propose dual-cathode *** epilepsy models with a wide distribution of PZ,it can inhibit the propagation of epileptiform activity in other nodes except EZ and PZ without increasing the tDCS current *** results provide theoretical support for the treatment of epilepsy with tDCS.

关键词： epilepsy large-scale brain network modeling transcranial direct current stimulation neural mass model

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Effect of microstructure on lipolysis behavior of milk fat globules during gastrointestinal digestion

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Food science and Human Wellness 2025年第5期14卷 1947-1957页

作者： Xinyun Zhou Ting Guo Chen Chen Hadiatullah Hadiatullah Yunping Yao Changmo Li Xingguo Wang State Key Laboratory of Food Nutrition and Safety Key Laboratory of Food Nutrition and SafetyMinistry of EducationCollege of Food Science and EngineeringTianjin University of Science&TechnologyTianjin 300457China Tianjin Key Laboratory for Modern Drug Delivery&High-Effi ciency Collaborative Innovation Center of Chemical Science and EngineeringSchool of Pharmaceutical Science and TechnologyTianjin UniversityTianjin 300072China Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province National Engineering Research Center for Functional FoodSchool of Food Science and TechnologyJiangnan UniversityWuxi 214122China

Milk fat globules(MFG)are the primary source of energy and functional factor in dairy-based *** evaluate the suitability of commercial MFG substitutes for infant and adult consumers,the lipolysis properties and regulatory factors in digesting bovine,caprine,and human MFG were *** lipolysis kinetic models of bovine and caprine MFG are comparable,with bovine MFG displaying the highest degree of lipolysis(50.21%)during gastric digestion in infants,resulting in the production short-chain saturated fatty *** MFG has a high rate of lipolysis due to its weak phospholipid-glycoprotein layer,which is prominent in both infants'and adults'*** effects of consuming bovine and caprine MFG for adults are comparable in terms of lipolysis properties and nutritional value of fatty *** gastrointestinal digestion,human MFG has the highest digestibility(93.98%).The advantages of human MFG include its phospholipid structure,exogenous lipase,and lipolysis-regulating *** study provides recommendation for the selection of milk fat substitutes and improvements in commercial dairy.

关键词： Milk fat globules Simulated digestion Microstructure Functional proteome

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Designing of multifunctional and flame retardant separator towards safer high-performance lithium-sulfur batteries

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Nano Research 2021年第12期14卷 4865-4877页

作者： Junling Wang Wei Cai Xiaowei Mu Longfei Han Na Wu Can Liao Yongchun Kan Yuan Hu State Key Laboratory of Fire Science CAS Key Laboratory of Soft Matter ChemistryUniversity of Science and Technology of ChinaHefei230026China Jiangsu Key Laboratory of Hazardous Chemicals Safety and Control College of Safety Science and EngineeringNanjing Tech UniversityNanjing211816China

Owing to unprecedented merits such as high theoretical capacity,superior energy density and low cost,lithium-sulfur batteries(LSBs)show a bright future both in scientific and industrial ***,the inherent issues,including highly insulating character,undesired shuttle behavior and lithium dendrites growth,are seriously impeding its practical ***,a metal-organic-frameworks(MOFs)derived N,S co-doped carbon nanotube hollow architecture confining with CoS_(2) nanoparticles(CoS_(2)/NSCNHF)modified separator is designed to surmount these *** with Celgard separator,this designed separator shows obviously enhanced flame retardancy,giving 73.1%and 53.0%reductions in peak heat release rate and total heat release,***,its hollow structure,conductive feature,electrocatalytic activity and Lewis acid-base interaction enable the efficient inhibition on shuttle behavior as well as boost in polysulfides conversion *** cell with modified separator delivers a high discharge capacity of 1,284.5 mAh·g^(−1).After running for 100 cycles,a discharge capacity of 661.3 mAh·g^(−1) is ***,the suppression on lithium dendrites growth is also observed,manifesting the enhanced battery ***,this work may shed light on the effective usage of MOFs-derived hierarchical composite in achieving LSBs with high electrochemical performance as well as safety.

关键词： metal-organic-frameworks shuttle behavior lithium dendrites flame retardancy

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Forecasting of Iron Ore Sintering Quality Index:A Latent Variable Method with Recurrent Inner Structure

Forecasting of Iron Ore Sintering Quality Index:A Latent Var...

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第33届中国过程控制会议

作者： Chong Yang Chunjie Yang State Key Laboratory of Industrial Control Technology College of Control Science and EngineeringZhejiang University

Accurate and real-time estimation of iron ore sintering quality index is essential for the stability of the production ***,the sintering process data is generally characterized by high dimensionality,collinearity,nonlinearity,and dynamic features,which seriously hinder the modeling *** cope with the complex properties mentioned above,an effective fusion of recurrent neural network with the gated recurrent unit and partial least squares(GRU-PLS) is introduced for FeO prediction of the finished *** proposed GRU-PLS model takes the advantage of conventional latent variable method but incorporates the deep inner structure between each pair of latent variables that captures the nonlinear and dynamic information *** modeling performance of the proposed model is evaluated by the actual data collected from the iron ore sintering process in a large iron and steel group in South *** results show the lowest prediction error of the GRU-PLS model in comparison with other *** specifically,the root-meansquare error of the GRU-PLS model is decreased by 35.29% in comparison with that for the recurrent neural network with the gated recurrent unit.

关键词： dynamic gated recurrent neural network partial least squares FeO prediction iron ore sintering process

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Multi-object Crowd Real-time Tracking in Dynamic Environment Based on Neural Network

Journal of Network Intelligence

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Journal of Network Intelligence 2022年第2期7卷 386-394页

作者： Zhang, Fu-Quan Ma, Lin-Juan College of Computer and Control Engineering Minjiang University Fuzhou China Digital Media Art Key Laboratory of Sichuan Province Sichuan Conservatory of Music Chengdu China School of Computer Science and Technology Beijing Institute of Technology Beijing China

In this paper, it proposes a new lightweight neural network detection model and tracking algorithm that enables us to perform multi-object crowd tracking. The technique applied in our study is known as object detection and tracking which is based on neural network and can be calculated and reproduced intelligently according to the movement and behavior of the tracked crowd. Also, a number of experiments have been carried out to test the validity of the accuracy in the algorithm. And it is indicated that the results of the experiments have better performance and can contribute to multi-object crowd real-time tracking with high accuracy, which is similar to the state-of-the-art. All our preliminary results throw light on the nature of detection and tracking and result in a solution of multi-object crowd tracking, and it proves to be fruitful and encouraging. © 2022, Taiwan Ubiquitous Information CO LTD. All rights reserved.

关键词： Object detection

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Design of B/N Co-doped micro/meso porous carbon electrodes from CNF/BNNS/ZIF-8 nanocomposites for advanced supercapacitors

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Journal of Bioresources and Bioproducts 2023年第3期8卷 292-305页

作者： Zhen Shang Xingye An Shuangxi Nie Na Li Haibing Cao Zhengbai Cheng Hongbin Liu Yonghao Ni Liqin Liu Tianjin Key Laboratory of Pulp and Paper Tianjin University of Science and TechnologyTianjin 300457China Guangxi Key Laboratory of Clean Pulp&Papermaking and Pollution Control College of Light Industry and Food EngineeringGuangxi UniversityNanning 530004China Department of Chemical Engineering University of New BrunswickFredericton NB E3B 5A3Canada Institute of Nuclear and New Energy Technology Tsinghua UniversityBeijing 100084China Zhejiang Jingxing Paper Co. Ltd.Pinghu 314214China

Boron(B)and nitrogen(N)co-doped 3D hierarchical micro/meso porous carbon(BNPC)were successfully fabricated from cellulose nanofiber(CNF)/boron nitride nanosheets(BNNS)/zinc-methylimidazolate framework-8(ZIF-8)nanocomposites prepared by 2D BNNS,ZIF-8 nanoparticles,and wheat straw based ***,CNF/ZIF-8 acts as versatile skeleton and imparts partial N dopant into porous carbon structure,while the introduced BNNS can help strengthen the hierarchical porous superstructure and endow abundant B/N co-dopants within BNPC *** obtained BNPC electrode possesses a high specific surface area of 505.4 m2/g,high B/N co-doping content,and desirable *** assembled with BNPC-2(B/N co-doped porous carbon with a CNF/BNNS mass ratio of 1꞉2)electrodes exhibited exceptional electrochemical performance,demonstrating high capacitance stability even after 5000 charge-discharge *** devices exhibited outstanding energy density and power density,as well as the highest specific capacitance of 433.4 F/g at 1.0 A/g,when compared with other similar *** study proposes a facile and sustainable strategy for efficiently fabrication of rich B/N co-doped hierarchical micro/meso porous carbon electrodes from agricultural waste biomass for advanced supercapacitor performance.

关键词： Cellulose nanofiber Zeolitic imidazolate framework Hexagonal boron nitride nanosheets B/N co-dopants Hierarchical structure Supercapacitor

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Tri-functional lanthanum-based biochar for efficient phosphorus recovery,bacterial inhibition,and soil fertility enhancement

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Biochar 2023年第1期5卷 302-318页

作者： Xiuxiu Jia Xue Zhao Yingtang Zhou Fan Li Wen Liu Yimin Huang Hucai Zhang Jinxing Ma Guangzhi Hu Institute for Ecological Research and Pollution Control of Plateau Lakes School of Ecology and Environmental ScienceYunnan UniversityKunming 650504China College of Chemistry and Engineering Yunnan Normal UniversityKunming 650092China National Engineering Research Center for Marine Aquaculture Marine Science and Technology CollegeZhejiang Ocean UniversityZhoushan 316004China Key Laboratory of Water and Sediment Sciences Ministry of EducationCollege of Environmental Sciences and EngineeringPeking UniversityBeijing 100871China Key Laboratory for City Cluster Environmental Safety and Green Development of the Ministry of Education School of EcologyEnvironment and ResourcesGuangdong University of TechnologyGuangzhou 510006China

Excess phosphorus(P)in water can lead to eutrophication and upset ecological *** this study,biochar with ultrathin two-dimensional nanosheets from the natural mesocarp of shaddock was chosen as the *** highly dispersed and small particle size of La(OH)_(3) on the surface of the nanosheets(MSBL3)was successfully achieved using chemical impregnation for the adsorption of P in aqueous solution,and the maximum adsorption capacity was 260.0 mg P g^(−1)[La].The differences in surface crystallization of La(OH)_(3) on biochar at different La loadings were analyzed using the high-precision characterization *** six adsorption-desorption cycles,MSBL3 retained 76.7%of its initial performance in terms of the P adsorption *** preparation of 1 g of MSBL3 costs about RMB 1,and it could reduce the P concentration in 2.6 ton of Laoyu River water to below the eutrophication threshold;and the inhibitory effect of MSBL3 on the eutrophication of water bodies was confirmed by the growth state of water ***,0.1 M MSBL3 could inhibit Escherichia coli and Staphylococcus aureus up to 98.7%and 85.0%,respectively,which indicates that MSBL3 can be used to recover P from water and also to improve water *** addition,the growth of the maize seedlings verified that the P-absorbed MSBL3 waste is a good soil fertilizer and can solve the problem of post-treatment of the *** conclusion,MSBL3 prepared in this study is a promising P sorbent for application.

关键词： Two-dimensional ordered biochar Lanthanum hydroxide phosphorus adsorbent Adsorption sludge re-planning Antibacterial

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Modeling and Research of Drivers' Learning Process

Modeling and Research of Drivers' Learning Process

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第34届中国控制与决策会议

作者： Yuxuan Yan Chunyue Song State Key Laboratory of Industrial Control Technology College of Control Science and EngineeringZhejiang University

Understanding the human driving process is one of the key factors in human-robot *** the real driving process,participants in driving are of varying levels and show different driving *** this paper,a driver learning model is built based on the students who are learning to drive,by observing the changes in the driving skills and styles of them in the process of *** a driver self-learning iterative process is built to characterize the learning level improvement process of the *** simulation results show that the different parameter combinations of the learner driving model can represent drivers of different levels and driving styles,and the learner model reflects the self-learning ability during the training process.

关键词： Driver Learning Model Self-Learning Driving Level Driving Style

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Direct laser writing breaking diffraction barrier based on two-focus parallel peripheralphotoinhibition lithography

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Advanced Photonics 2022年第5期4卷 56-63页

作者： Dazhao Zhu Liang Xu Chenliang Ding Zhenyao Yang Yiwei Qiu Chun Cao Hongyang He Jiawei Chen Mengbo Tang Lanxin Zhan Xiaoyi Zhang Qiuyuan Sun Chengpeng Ma Zhen Wei Wenjie Liu Xiang Fu Cuifang Kuang Haifeng Li Xu Liu Zhejiang Lab Research Center for Intelligent Chips and DevicesHangzhouChina Zhejiang University College of Optical Science and EngineeringState Key Laboratory of Modern Optical InstrumentationHangzhouChina Zhejiang University College of Control Science and EngineeringState Key Laboratory of Industrial Control TechnologyHangzhouChina Zhejiang Lab Research Center for Humanoid SensingZhejiang LabHangzhouChina

Direct laser writing(DLW)enables arbitrary three-dimensional ***,the diffraction limit poses a major obstacle for realizing nanometer-scale ***,it is challenging to improve the fabrication efficiency using the currently prevalent single-focal-spot systems,which cannot perform high-throughput *** overcome these challenges,a parallel peripheral-photoinhibition lithography system with a sub-40-nm two-dimensional feature size and a sub-20-nm suspended line width was developed in our study,based on two-photon polymerization *** lithography efficiency of the developed system is twice that of conventional systems for both uniform and complex *** proposed system facilitates the realization of portable DLW with a higher resolution and throughput.

关键词： optical fabrication parallel direct laser writing peripheral-photoinhibition diffraction barrier breaking

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Study of Switching control based on Dwell Time for Aero-Engines

Study of Switching Control based on Dwell Time for Aero-Engi...

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第43届中国控制会议

作者： Ling Xu Xian Du Yanhua Ma Honglei Wang School of Control Science and Engineering Dalian University of Technology Key Laboratory of Intelligent Control and Optimization for Industrial Equipment Dalian University of Technology School of Integrated Circuits Dalian University of Technology

ISBN: (数字)9789887581581

ISBN: (纸本)9798350366907

To address the issue of control signal chattering near the switching point for aero-engine switching system,an optimized control strategy that combines state-dependent switching law with a dwell time constraint and the tracking controller based on internal model is proposed. Firstly,internal model-based tracking controller with no static error is designed separately for the speed control and temperature protection control loop. Then,dwell time and system state are introduced into the switching law,proposing a switching law which depends on time and event. Moreover,the stability of the switching system is proved using the multiple Lyapunov function method. Finally,the validity of the proposed strategy is verified through digital simulation and hardware-in-the-loop(HIL) test. The results demonstrate that the proposed switching control strategy effectively reduces the temperature overshoot by 2.8% and the number of switching times by more than 90% compared to the conventional method. In addition,the proposed controller mitigates control signal chattering and has the feasibility of practical engineering application.

关键词： Aero-engine Switching control strategy Dwell time Internal model control Limit protection control

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