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Isoform Function Prediction Based on Heterogeneous Graph Attention Networks

Isoform Function Prediction Based on Heterogeneous Graph Att...

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2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Guo, Kuo Li, Yifan Chen, Hao Shen, Hong-Bin Yang, Yang Shanghai Jiao Tong University Key Lab. of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Department of Computer Science and Engineering Shanghai200240 China Shanghai Jiao Tong University Key Laboratory of System Control and Information Processing Ministry of Education of China Institute of Image Processing and Pattern Recognition Shanghai200240 China Carnegie Mellon University School of Computer Science Computational Biology Department PittsburghPA15213 United States

ISBN: (纸本)9798350337488

Isoforms refer to different mRNA molecules transcribed from the same gene, which can be translated into proteins with varying structures and functions. Predicting the functions of isoforms is an essential topic in bioinformatics as it can provide valuable insights into the intricate mechanisms of gene regulation and biological processes. Conventionally, gene function labels are standardized in Gene Ontology (GO) terms. However, traditional methods for predicting isoform function are largely limited by the absence of isoform-specific labels, sparse annotations, and the vast number of GO terms. To address these issues, we propose HANIso, a deep learning-based method for isoform function prediction. HANIso leverages a pretrained protein language model to extract features from protein sequences. It also integrates heterogeneous information, such as isoform sequence features, GO annotations, and isoform interaction data, using a Heterogeneous Graph Attention Network (HAN). This allows the model to learn the importance of different sources of information and their semantic relationships through the attention mechanism. Our method can predict function labels at both the gene level and isoform level. We conduct experiments on two species datasets, and the results demonstrate that our method outperforms existing methods on both AUROC and AUPRC. HANIso has the potential to overcome the limitations of traditional methods and provide a more accurate and comprehensive understanding of isoform function. © 2023 IEEE.

关键词： alternative splicing gene ontology heterogeneous graph attention network isoform function prediction protein language model

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Multifeature distance map based detection of small infrared targets with low contrast in image sequences

Multifeature distance map based detection of small infrared ...

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International Conference on Space Information Technology

作者： Wang, Zhicheng Gao, Chenqiang Tian, Jinwen Liu, Jian Chen, Xiangping State Education Commission Key Lab for Image Processing and Intelligent Control Huazhong University of Science and Technology Wuhan Hubei 430074 China Inst. for Pattern Recognition and Artificial Intelligence Huazhong University of Science and Technology Wuhan Hubei 430074 China Electronic and Engineering Department Huazhong University of Science and Technology Wuhan Hubei 430074 China

Target detection techniques play an important role in automatic target recognition (ATR) systems because overall ATR performance depends closely on detection results. In this paper, a novel method for fusion detection of infrared weak targets based on multifeature distance map (MFDM) in image sequences is proposed. As for small weak targets, there are many features, such as local entropy, average gradient strength. These features depict the characteristics of small infrared targets and can be extracted. Multifeature-based fusion techniques are applied to detect such weak targets. The problem of detecting small targets is converted to search peak values in specified feature space where multifeature vectors space (MFVS) is considered. Distance map (DM) can be derived according to feature vectors and target detection is performed in DM. In order to accumulate energy of targets deeply and suppress background and clutters to a great extent, five distance maps obtained by corresponding five consecutive frames are utilized to fuse with average weight, which results in the fact that the contrast between targets and background including clutters are enlarged and that the feature peaks of targets are obvious different from background and clutters. After these steps, a contrast segmentation method is used to extract targets from complicated background on the fused DM. Actual infrared image sequences in background of sea and sky are applied to validate the proposed approach. Experimental results demonstrate the robustness of the proposed method with high performance.

关键词： Automatic target recognition

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3-D temperature field reconstruction of lithium-ion battery pack using real-time distributed moving horizon estimation

3-D temperature field reconstruction of lithium-ion battery ...

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第35届中国控制与决策会议

作者： Jiayu Yan Yiming Wan School of Artificial Intelligence and Automation Huazhong University of Science and Technologyand Key Laboratory of Image Processing and Intelligent ControlMinistry of Education

As lithium-ion batteries are widely used in different fields,the thermal effect is of serious *** to achieve accurate temperature estimation in real time is the main challenge of current *** address this problem,we propose a realtime distributed moving horizon estimation(RT-DMHE) based on partial differential equations describing thermal dynamics of a lithium-ion battery *** decomposes the real-time centralized moving horizon estimation(RT-CMHE) into multiple local estimators that run in parallel with information exchange from adjacent *** validation shows that the root mean square error of temperature estimates from the proposed RT-DMHE is smaller than that of an existing distributed Kalman filter in ***,compared to the RT-CMHE,the proposed RT-DMHE achieves comparable estimation accuracy while vastly reducing the average computation time per sample.

关键词： lithium-ion battery pack distributed moving horizon estimation real-time computation state-of-temperature estimation

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Decoupling guaranteed cost control of BTT vehicle based on LMI

Decoupling guaranteed cost control of BTT vehicle based on L...

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IEEE International Conference on intelligent Computing and intelligent Systems (ICIS)

作者： Zhixiang Deng Yongji Wang Lei Liu Chuanfeng Li Key Laboratory of Ministry of Education for Image Processing and Intelligent Control Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan China

ISBN: (纸本)9781424447374;9781424447541

This paper presents a new approach for coupling control problems for norm bounded continuous-time uncertain systems. Firstly, a design of the state feedback decoupling controller is presented. The nominal model could be decoupled completely and the coupling of the actual system would be reduced. Secondly, based on the linear matrix inequality (LMI), combining the guaranteed cost control law with the decoupling control, the state feedback tracking guaranteed cost control law is proposed. Finally, taking BTT vehicle as the research objective, the design procedure of the decoupling guaranteed cost controllers is shown and the final results of the simulation are proved with effectiveness for the proposed design approach.

关键词： Costs Vehicles control systems Uncertain systems Robust control state feedback Linear matrix inequalities Linear feedback control systems Uncertainty Missiles

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High-Precision Discrete Convolution Algorithm Based on Moments

High-Precision Discrete Convolution Algorithm Based on Momen...

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WRI International Conference on Communications and Mobile Computing, CMC

作者： Jianguo Liu Zhenbing Liu Guoyou Wang Key Laboratory of Education Ministry for Image Processing and Intelligent Control State Key Laboratory of Multispectral Information Processing Technologies Institute of Pattern Recognition and Artificial Intelligence Huazhong University of Science and Technology Wuhan China

Convolution is an important and useful operation in the fields of digital signal processing. In this paper, based on the previous work of performing discrete Fourier transform (DFT) via linear sums of discrete moments, we have made development to eliminate multiplications in discrete Fourier transforms by performing appropriate bit operations and shift operations in binary system, which can be implemented by integer additions of fixed points; then using the convolution theorem with the DFT, we compute the convolution with two DFTs, a point-by-point product, and an inverse DFT. Our algorithm involves fewer multiplications and can deal with arbitrary length signals.

关键词： Convolution Signal processing algorithms Discrete Fourier transforms Very large scale integration Algorithm design and analysis Laboratories educational technology Digital signal processing Mobile communication Mobile computing

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Extended state observer based non-iteration predicted entry guidance

Extended state observer based non-iteration predicted entry ...

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International Conference on Modelling, Identification and control (ICMIC)

作者： Songtao Chang Mao Su Da Zhang Yongji Wang Department of Control Science and Engineering Key Laboratory of Ministry of Education for Image Processing and Intelligent Control Huazhong University of Science and Technology Wuhan China

It is difficult to guide the entry vehicle to prescribed area due to the disperse of environment and kinematics. Through predicted residual range at the current state based on drag acceleration, we developed a predictor-corrector guidance law which doesn't need iteration to figure out the reference trajectory. Then using extended state observer based controller to track the reference trajectory. We use several missions(under various disperse conditions) to test the guidance law. Simulation results demonstrated that the guidance law is able to achieve the prescribed terminal conditions under various perturbations in the aerodynamic coefficients, the density of the atmosphere and the mass of the vehicle.

关键词： Acceleration Trajectory Vehicles Observers Vehicle dynamics Planning Earth

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Active Disturbance Rejection Guidance for Ascent Using Quadratic Transition

Active Disturbance Rejection Guidance for Ascent Using Quadr...

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International Symposium on Computer, Consumer and control (IS3C)

作者： Xuefang Lu Yongji Wang Key Laboratory of Ministry of Education for Image Processing and Intelligent Control Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan China

This paper presents an active disturbance rejection guidance method using quadratic transition for the atmospheric ascent guidance problem. The quadratic transition is designed from the current flight states with a reference trajectory planned off-board. For any states error, the solution of the designed quadratic transition converges to the reference trajectory. The guidance command is obtained from the derivative of the designed quadratic transition. For the unknown modeling error, the guidance command is compensated using the estimated disturbances from the extended state observer. Computer simulation for GHV (Generic Hypersonic Air Vehicle) model, which includes initial states error and modeling error, shows great accuracy and effectiveness of this guidance method.

关键词： Trajectory Atmospheric modeling Computational modeling Aerodynamics Vehicles Observers Accuracy

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Channel and Trials Selection for Reducing Covariate Shift in EEG-based Brain-Computer Interfaces

Channel and Trials Selection for Reducing Covariate Shift in...

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IEEE International Conference on Systems, Man, and Cybernetics

作者： He He Dongrui Wu Key Laboratory for Image Processing and Intelligent Control Ministry of Education and the School of Artificial Intelligence and Automation Huazhong University of Science and Technology

ISBN: (纸本)9781728145709

This paper aims at reducing the calibration effort of EEG-based brain-computer interfaces (BCIs). More specifically, in the context of cross-subject classification, we correct covariate shift of EEG data from different subjects, so that a classifier trained on auxiliary subjects can also be applied to a new subject, without any labeled trials from the new subject. Methods: We propose two approaches to enhance the performance of a state-of-the-art Riemannian space transfer learning (TL) algorithm: 1) trials selection, which resamples trials from the auxiliary subjects so that they become more consistent with those of the new subject;and, 2) channel selection, which reduces the number of channels and hence makes the Riemannian space computations more accurate and efficient. Results: We tested the proposed approaches on two motor imagery datasets. The results verified that they can enhance the performance of the state-of-the-art TL algorithm. Conclusion and significance: Our proposed approaches make the state-of-the-art TL algorithm more effective and efficient.

关键词： Brain-Computer Interfaces experimentation Trials Computer interfaces Thallium Shift Classifiers biological control 2-channel

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keypoint-Based Feature Matching For Partial Person Re-Identification

Keypoint-Based Feature Matching For Partial Person Re-Identi...

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IEEE International Conference on image processing

作者： Chuchu Han Changxin Gao Nong Sang Key Laboratory of Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology

ISBN: (数字)9781728163956

ISBN: (纸本)9781728163963

As a derivative of person re-identification (re-ID), partial re- ID aims to retrieve a partial pedestrian across holistic person images captured by non-overlapping cameras. This task is more challenging and closer to real-world applications. Since we cannot locate the part of the partial image, the misaligned region compromises the performance greatly when directly (a) compare a partial pedestrian with a holistic one. To alleviate this issue, we propose a keypoint-Based Feature Matching (KBFM) network, which constructs a simple and effective framework for partial re-ID. Specifically, our architecture explicitly leverages the keypoints generated by pose estimation. Based on the visible keypoints, coordinates of the corresponding visible region can be computed. And the keypoint-based feature embeddings can be generated by bilinear sampling. When matching two images, we extract their features on the basis of shared visible keypoints, avoiding the misalignment and disturbance. Moreover, considering the triplet loss cannot be flexibly built in the partial re-ID pipeline, we improve the original sampling method and achieve significant performance. Extensive experimental results on two widely used benchmarks demonstrate significant performance improvements of our method over most state-of-the-art methods.

关键词： Feature extraction Cameras Task analysis Pose estimation Training Pipelines Generative adversarial networks

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High-Precision and Arbitrary-length Fixed-Point Fast Hartley Transform without Multiplications

High-Precision and Arbitrary-length Fixed-Point Fast Hartley...

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WRI International Conference on Communications and Mobile Computing, CMC

作者： Zhenbing Liu Jianguo Liu Guoyou Wang Key Laboratory of Education Ministry for Image Processing and Intelligent Control State Key Laboratory of Multispectral Information Processing Technologies Institute of Pattern Recognition and Artificial Intelligence Huazhong University of Science and Technology Wuhan China

Discrete Hartley transform (DHT) is an important tool in digital signal processing. In this paper, based on our previous work of performing DHT via linear sums of discrete moments, we have made development to eliminate multiplications in discrete Hartley transforms by performing appropriate bit operations and shift in binary system, which can be implemented by integer additions of fixed points. An efficient and regular systolic array is designed to implement it, and the complexity analysis is also given. Different to other fast Hartley transforms, our algorithm can deal with arbitrary length signals and get high precision. The approach is also applicable to multi-dimensional DHT and DHT inverses.

关键词： Discrete transforms Signal processing algorithms Digital signal processing Systolic arrays Laboratories educational technology Very large scale integration Hardware Mobile communication Mobile computing

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